365 Kinds of Difficult Living Methods

In the conference room, Fang Datuo didn't say anything. He pushed the MRI image and various substance level data in front of Chu Yu, turned on the computer, and some dynamic images needed to be projected on the screen.

Chu Yu went through the examination data similar to the physical examination report, and then scanned the brain images, and found that it was the same as the examination result at Jinshui Hospital. According to this result, Xia Yihan is a complete physical and mental health. Normal person.

If you spend time watching it slowly and it takes too much time, Chu Yu directly asks the consignment to dry the goods: "If you have any discoveries or doubts, let me tell you the truth, I can resist it!"

For Xia Yihan’s condition, Chu Yu was mainly responsible for the psychological factors, and Fang Datuo, this time mainly started from neurobiology, to find out the cause of Xia Yihan, including hereditary basis, neurotransmitter, hormone system, autonomic nervous system and Research on the functional structure of the brain.

He took the brain map, flipped a few, and arranged it in front of Chu Yu’s eyes. “First, start with the functional structure of the brain. Her PFC (prefrontal cortex), OFC (orbital frontal cortex), VMPEC (ventromedial prefrontal cortex) ), DLPFC (the dorsolateral prefrontal lobe) and ACC (anterior spine gyrus) are all developed normally, and there is no insufficient cortical thickness."

The prefrontal cortex is closely related to self-control, impulsivity, and executive function, and affects emotional response and moral decision-making, as well as the processing and evaluation of emotional stimuli in life. If the structure of the prefrontal cortex is abnormal, people will be impulsive and have executive dysfunction. , Lack of responsibility and remorse-these are the characteristics of patients with antisocial personality disorder.

Chu Yu stared at the image, and the normal brain map had been engraved into her brain. Comparing the two, she knew that everything was normal, the structure was normal, and the development was sound.

However, she is not surprised that there are obvious differences between Xiaohuahua and ordinary patients. For example, she is not impulsive, meticulous in thinking, does not leak anything, can recognize emotions and imitate, which shows that at least her cerebral cortex is well-developed and there is no obvious dysfunction.

Pointing to the location of the amygdala in the finger picture, Fang Datuo continued: "Generally speaking, ASPD (Antisocial Personality Disorder) amygdala is small in size and has local abnormalities, such as deformation of the base of the amygdala, basolateral and central nucleus. , But Xiaohuahua does not have this problem. Her amygdala is perfect from volume to structure."

Looking at the diffusion tensor imaging, Chu Yu nodded: "The right hook bundle (the white matter bundle connecting the prefrontal lobe and the amygdala) is also normal."

The amygdala is closely related to emotional processing and participates in moral decision-making. If there is a problem with it, the patient will lack sympathy and regret. At the same time, the connection between the amygdala and other brain regions is also particularly important. The amygdala can generally be divided into the basolateral amygdala and the central medial amygdala.

The outside of the base is responsible for receiving information, which is related to the perception and memory of emotional information.

The central medial amygdala is the output nucleus, which transmits physiological and behavioral signals related to emotions to the brainstem, cerebellum, and hypothalamus.

If the prefrontal cortex over-controls the lateral amygdala of the base, the patient will not be able to pay attention to, perceive and learn emotional information. If the cortex does not control the central medial amygdala too much, the amygdala will be overactive and move to the brainstem, hypothalamus, etc. The autonomic nervous system outputs more negative emotions, and patients will be impulsive and attack others.

Regarding these two items, Fang Datuo explained: "The control of PEC (prefrontal cortex) on the amygdala cannot be concluded yet, and it must be combined with later experimental results."

Chu Yu nodded: "Are you going to give Xiao Sophora a certain amount of stimulation and check her brain activity under specific conditions?"

Fang Datuo nodded, "Yes, this is also particularly important for the striatum. Although the picture shows that the size of the striatum of the small Sophora japonica is no different from that of ordinary people, it depends on her left side when facing the rewarding stimulus. The degree of activation of the striatum."

Chu Yu nodded, agreeing with his method.

The striatum, especially the nucleus accumbens in the ventral striatum, can affect people’s reward preferences. For example, under the action of monetary stimulation and drugs, the release of dopamine from the nucleus accumbens will increase, which makes antisocial personality People with disabilities get more excitement and pleasure.

Chu Yu finished the axial slice, supporting his chin, "Tell me about the hippocampus."

"In terms of volume and structure, the hippocampus is not abnormal. I also compared the hippocampus of Xiaohuahua with mine. Hers is healthier than mine."

Chu Yu laughed, "This is abnormal. You are a super-IQ researcher. If her hippocampus is better than yours, isn't it just super-normal performance, frantic testing on the edge of crime?"

Fang Datuo was a little embarrassed for such high-profile praise. On weekdays, he has always been proud of his hippocampus, and he painted it, hung it on the wall, and marked it specifically to show off.

But Chu could understand better. Muyu and Song Qingyang asked their souls when they passed by: "Is this a sausage painted by Datuo? Which variety can be bent into this way, so tough!"

Fang Datuo angrily tore off his hippocampus jade, and there is a long-term wearing of luxury goods worth more than 10,000, but he is considered to be too poor to change clothes.

Chu understands his sadness better, because the hippocampus is the spokesperson of learning ability.

As an important part of the limbic system, the hippocampus has memory and learning functions. If the hippocampus is asymmetry, psychopathic behavior may occur-psychopathy is an extreme antisocial personality disorder with obvious aggressive tendency.

In addition, the hippocampus is also an important memory function area. In the human brain, the parts related to memory are the temporal lobe, hippocampus and diencephalon. The temporal lobe belongs to the neocortex of the brain, and the temporal lobe memory is located in the superficial layer of the memory hierarchy, which is easier to forget.

The hippocampus belongs to the old cortex of the brain, and its memory is located in the deep layer of the memory hierarchy, and the memory is relatively strong; the diencephalon belongs to the brainstem, and the diencephalon memory is a deeper memory.

The hippocampus controls the core part of memory.

When the brain is particularly interested in certain types of information, or the information is constantly repeated, the brain thinks that the information is extraordinary, and it not only stores it in the temporal lobe, but also transmits it to the hippocampus through the nervous system.

It is difficult for people to control or change the deep memory circuits in the hippocampus through willpower.

The memory content in the hippocampus unknowingly affects people. If people can remember things about five or six years old, it is because they have entered the deep memory of the hippocampus.

Chu Yu remembered Xia Yihan’s dream. It was probably a real scene, which stimulated Xia Yihan too much, so he dreamed it repeatedly, but because of repeated dreams, the memory was deeper and stored in the deep hippocampus. Form, and at the same time affect her behavior.

She is now carving acacia flowers everywhere, which is affected by that dream. This dream is reflected in the psychological and spiritual level and is the heart knot for the treatment of Xia Yihan, and reflected on the real criminal investigation level is to solve the crux of the unsettled case. A dream connects the mind and reality. The ends are connected and interlocked. As long as one end is opened, the other end can be solved easily.

But Chu Yu worked hard for so long, still feeling ignorant. He moved forward in the thick fog, touching his hands forward, trying to find the iconic landmark building, only to find that he had only reached the periphery of the mystery and did not formally step into it.

After talking about the structure of the brain, Fang Datuo turned to signal transduction substances, "Next is the level of neurotransmitters and hormones. Through PET (positron emission tomography) and fMRI (functional magnetic resonance imaging), you can see the small locust flower. Her dopamine system is normal, and I found that the concentration of serotonin in the orbital frontal cortex on both sides of her is the same as that of normal people. However, based on later experiments, using the amount of dopamine secretion as an indicator, look at her when she is facing stimulation. Dopamine system activity level."

Dopamine and serotonin are neurotransmitters. The former plays an important role in the brain's reward process. The release of dopamine will make people happy. On the other hand, aggressive behavior can also make people feel happy. When the dopamine system is too active or not active enough, it can trigger aggressive behavior.

Serotonin is related to emotion and behavior control. Xia Yihan's serotonin concentration is normal, indicating that she can better control her emotions and behaviors compared to the general anti-social personality disorder.

But this did not make Chu even more pleased, because the normal serotonin can only show that people are not easy to initiate impulsive attacks, and it has no obvious meaning to premeditated attacks. And Xia Yihan's "Sophora japonica" is a model of premeditated crime!

While listening to Fang Datuo, Chu Yu looked at various indicators and quickly scanned the hormones column. "Testosterone and cortisol concentrations are normal, but there are no daily rhythms and changes in cortisol concentration under stressful situations. 【1】"

"Yes, this requires all-day follow-up of Xiaohuaca in the future to detect the level of its various substances."

Chu Yu put the data sheet in his hand and asked, "So, is there anything abnormal in this inspection?"

Fang Datuo shrugged: "No, the brain function structure, neurotransmitters, and hormone levels in front. I also checked her autonomic nervous system, and the resting heart rate is not lower than that of ordinary people. [2]"

Although he expected this result, after hearing it with his own ears, Chu Yu still felt that the five flavors were mixed and the test results were not abnormal. This is a good thing. It shows that Xia Yihan has various normal functions and there is no organic problem, but On the other hand, the reason cannot be found, the right medicine cannot be prescribed, and the targeted biological assistance cannot be carried out.

Although Chu Yu’s current psychological interventions have been very effective and convinced Xia Yihan to be willing to receive treatment, it is far from enough. At least in terms of Xia Yihan’s emotional dysfunction, it must be understood from a deeper level of causes and factors. The mechanism starts to assist psychotherapy.

The next content no longer needs a projector. Fang Datuo put down the infrared pen and turned to Chu Yu, "Boss, I can check and analyze these neurobiological indicators, but the early environment has a negative impact on ASPD (anti-social personality disorder). Formation is also closely related. I don’t know much about Xiaohuahua’s childhood experience. Can you contribute a little?"

When Chu Yu heard this, she was encouraged. The information she had picked up from Xia Yihan for so many days finally became useful. "Little Sophora has a bad childhood. Her mother is suspected of having depression. Or schizophrenic personality disorder. This shows that Xiaohuahua has genetic genes and is susceptible to mental illness [3]. On the other hand, the mother’s indifference to her has also caused emotional deprivation, which is in the emotional attachment. Loss of security, emotional damage, and indifferent response to external stimuli."

Fang Datuo nodded: "Does her mother have a habit of smoking and drinking?"

Chu Yu shook her head. She asked Xia Yihan about this and was denied. Huang Nan doesn't have any bad habits except for not caring about people. He doesn't even scold Mu Shangqing and Xia Yihan, and treats them as air.

"Have she suffered any abuse or severe blows in her childhood?"

Chu Yu shook his head first, and then fell into deep thought: "As far as I know, no. But not necessarily. Sometimes, for memories that are too painful, especially those that occur in childhood, the human brain will choose to forget and protect itself. If I don’t think about it, I won’t hurt myself again, but sometimes it will be shown in the form of dreams, such as Xiaohuaihua’s dream, I suspect it is a serious trauma!"

Fang Datuo nodded thoughtfully, "Have you tried to solve her dream before?"

Chu Yu glanced at him: "I have been trying. The first time I came here, I directly forced hypnotism. As a result, she overstressed and almost screwed my hand off."

Fang Datuo smiled gleefully. Although he can't analyze the cause of Xia Yihan himself, it does not prevent him from laughing at Zhuhei. ...Ahahahaha!"

Chu Yu narrowed his eyes and stared at him motionlessly. The needle seemed to fly out of his eyes, and the needle was still stained with poison.

Fang Datuo laughed for a while, and Chu Yu's eyes pierced a few times. The rules came to an end. The laughter stopped abruptly, and he packed up the information on the table.

"Chu, do you want Xiao Huaihua to meet us? It's okay, take her down. According to the current analysis results, her brain functions are normal, and there is no tendency to impulsive aggression, which can be controlled. Our own actions, and with you, we should not be in danger."

Chu Yu nodded, solemnly: "Well, if the follow-up experimental research shows that her data is normal, I will take her on the knife-such a large ‘clue library’ is placed in front of us, and it cannot be wasted!"