godfather of surgery

Chapter 1036 System Vacation
Huang Jiacai reported a lot, but Yang Ping didn't really listen. His mind was not on these things, but on thinking about his own project.

Anyway, Yang Ping trusted Huang Jiacai to do the job. After he finished his report, Yang Ping just nodded symbolically.

After Huang Jiacai left, Yang Ping began to think about his own research topic again. Brian has made great achievements in immunology. In the field of immunology, some of Brian's laboratory methods are absolutely the most advanced in the world. Yang Ping has communicated with him intentionally or unintentionally during this period, and has learned a lot of knowledge in immunology. This knowledge is very meaningful to his scientific research, and some of it can even directly replace the original laboratory methods and improve experimental efficiency.

Yang Ping's current research on tumors will definitely apply knowledge from immunology, because after the M13 phage is modified, it must not provoke the immune system, otherwise all previous efforts will be wasted, and when marking tumor cells, a lot of immunology knowledge is also involved, such as knowledge about antigens. Research on tumor treatment cannot avoid immunology, and now that there is such a great man here, Yang Ping will definitely squeeze out his knowledge.

The modification of M13 phage includes several parts. The K factor is transplanted onto the M13 phage, and then a molecule that can be paired with a certain marker substance on the surface of tumor cells is found, and this pair of molecules is used for positioning, identification and coupling. Equivalent to the navigation of a missile, the modified M13 phage must also have its own navigation system to be able to identify and connect to the tumor system.

The whole process is very complicated and involves knowledge of targeted therapy, but these difficulties are not difficult for Yang Ping. Even if there is no system, Yang Ping will face the challenges head-on.

Yang Ping took this time to enter the system and began to prepare for the experiment, but after entering, he found that the system space was empty, instead of everything. What was going on? Why was there only a pure space? The previous system panels, equipment, and experimental subjects were all gone.

When Yang Ping was wondering, a series of words appeared in the air: The system entered a dormant period with an unlimited dormant time in order to test the host's real knowledge and skills.

What's happening here?
Yang Ping had read a lot of online novels before. Although he was not very knowledgeable, he knew a thing or two. He had never heard of the system going on strike, and even called it a test to see whether the host had learned real knowledge and skills by using the system.

Is this a test of the time I have been implanted in the system? Is this a test of whether I have made good use of the system?
"The countdown for system space contraction begins, 10-9-8-"

Before Yang Ping could react, the system space began to shrink, getting smaller and smaller, until it completely shrunk into a point. Yang Ping was forced to come out of the system space.

Damn, the system has done this to me. Now I have no use for the system, and I don’t know how long this will last. Fortunately, I am quite diligent. Since I got the system, I have been immersed in it almost day and night. I have read all the books in it many times, and I have made use of all the functions of the system. I am almost squeezing the value of the system all the time. I don’t know if it is due to over-development that the system is overwhelmed. Now I need to take a break.

Although the system's dormancy was somewhat unexpected, Yang Ping was not too sad because he had made plans for the system's departure since the first day he got the system. So the system's temporary vacation did not have much impact on him, at least not psychologically. He had always regarded the system as a tool and did not rely on it absolutely.

Although there is no system available at the moment, Yang Ping's work is still proceeding as normal.

He first started to study the transformation plan of M13 phage with paper and pen in his office. He drew an image of M13 phage, and then expressed its structure clearly, marking all the parts that can be disassembled and assembled. Then facing this picture, Yang Ping thought about where to assemble the K factor and the navigation factor.

Yang Ping found that the training in the system during this period of time has helped him to improve his thinking, memory and concentration, and become very strong. In fact, the system space not only allows him to learn knowledge, but also allows him to hone his abilities. He tried several solutions to assemble the K factor and the navigation factor on the M13 bacteriophage.

This step was not difficult for Yang Ping, as the K factor, or tumor-killing factor, was already available, and the results of in vitro experiments were very good. However, there was no suitable substance for the navigation factor, which was the difficulty this time.

In order to make this missile attack tumor cells accurately, Yang Ping needs to obtain a large amount of information about the target of tumor cells. Lu Xiaolu has been studying this topic in the laboratory and has collected some information in this regard. After finding out the target of tumor cells, we can then connect the target to study the navigation factor, because they are a pair that must interact. The navigation factor must rely on the target to identify tumor cells. Once the recognition is completed, the M13 phage combines with the tumor cell and injects the K factor into the tumor cell, starting the apoptosis program of the tumor cell and completing the hunting of the tumor cell.

Without the opportunity for trial and error in the system space, Yang Ping could only start in-depth research on the target on his own, hoping to summarize a set of theories to screen the targets, which would save a lot of time and reduce the number of trial and error.

Yang Ping was used to closing his eyes and resting. He leaned back in his chair with his eyes closed, immersed in his own thoughts and giving full play to his wild imagination.

How to make the modified M13 phage find tumor cells? Different tumor cells have both similarities and obvious differences, so in the future, M13 phages must be personalized for different tumor cells to make them have affinity for one or a type of tumor cells.

Just as the hepatitis B virus has strong selectivity for stem cells, how can the modified M13 phage recognize the current experimental tumor cells - Sisi's tumor cells.

Someone knocked on the door, and Yang Ping came back to his senses from his thoughts: "Come in!"

The one who came in was Song Zimo: "I heard that Mr. Zhang has severe body aches. Do you want to go see him?"

"Are the symptoms serious?" Yang Ping was quite worried.

Song Zimo said, "It should be quite serious. I heard that he couldn't hold on any longer. Just now, Fatty Liang, Zhang Lin, Xiao Wu and several others went to Mr. Zhang's house. They were all in a hurry when they went there."

"How come these guys went to see Mr. Zhang alone without telling us?" Song Zimo felt strange.

"Yeah, how come I don't have any news at all?" Yang Ping checked his cell phone, which still had power.

A graduate student was walking hurriedly outside the door with a bag on his back. Song Zimo stopped him and asked, "Where are you going?"

"I'm going to Mr. Zhang's house?" said the graduate student.

"What happened to Mr. Zhang? I heard Zhang Lin on the phone say he couldn't hold on any longer. What's going on?" Song Zimo asked.

The graduate student immediately said, "Oh, he hasn't played the game for several days, and he couldn't stand it anymore, so he asked a few friends to go to his house to play a game together today--"

Yang Ping and Song Zimo were immediately confused.