godfather of surgery

Chapter 355 Old Irons

Yang Ping chose stem cells to cultivate muscle as a subject, not on a whim, but after careful consideration.

If successful, it will be easier later to transition to growing other organs, such as skin, tendons, ligaments, cartilage, bones, and even joints.

In the long run, it can also develop towards the cultivation of hearts, livers, kidneys, etc.

The organization technology and equipment of this project will be relatively more convenient, such as nano-micro-stents, which are relatively easy to obtain through Takahashi.

Nano-micro-scaffolds have very high requirements for 3D printing technology. Its three-dimensional structure arrangement is at the level of cell clusters, and it must be able to guide muscle fibers in spatial configuration.

This level of 3D printing technology is currently not available in China, and the core technology is monopolized by German and Japanese companies.

This is also the reason why Yang Ping seeks international cooperation. It is impossible for one person to break through all industrial technologies, and he can only work hard in medical technology.

The obstacle that the United States and Japan cannot overcome now is the collapse of cells. The collapse stems from the instability of certain cell structures. There are many factors of instability, such as cell membrane instability or organelle instability.

Many papers now assume that there are all kinds of collapse factors. Any one of these collapse factors can be used as an initiating factor to cause cell collapse and lead to the collapse of other structures.It is not surprising that researchers focus on one side when observing for various reasons.

This is the inevitable result of artificially inducing stem cell differentiation. In the case of immature induction technology, it will inevitably cause some structural instability, which is the potential cause of the collapse.

In fact, the development of stem cells in organ cultivation has been in full swing.

The University of Tokyo also cultivated the world's first heart with a diameter of 1 mm and a complete structure of ventricles and atria, which is about the size of a mouse fetal heart.

Also Japan's National Center for Reproductive Medicine cultivated livers; the University of Edinburgh in the United Kingdom cultivated kidneys; Harvard University in the United States cultivated skin.

These technologies all face a common problem - maturity and stability.

If this problem is solved, these technologies can move from the laboratory to the clinic.

Muscle cultures are currently the most mature, and can be transplanted into animals for several weeks of survival.

Those internal organs, such as the heart, a small heart with a diameter of only one millimeter, will face the problem of collapse if it is further cultivated, and the small heart cannot grow smoothly.

Yang Ping wants to start with the muscles to solve the problem of maturity and stability.

Then it extends to skin, tendon, cartilage, etc., which are widely used in orthopedics.

With the skin, there is no need for skin grafting or skin flaps.

With the tendon, those patients who underwent ligament reconstruction would do better with surgery.

With cartilage, cartilage degenerative diseases, such as senile knee osteoarthritis, can be solved.

A joint was even grown for joint replacement.

Stem cells are the most promising field of future surgery, which will change the history of surgery.

Perhaps one day, a patient like Yu Shuilian can use her own cells to grow a complete lower body, and then undergo a transplant operation to connect the upper and lower body to restore a complete body.

After get off work in the afternoon, the young doctors of general orthopedics, whenever they are free, will go to Mr. Guo's dinner.

Mr. Guo was so generous that he set up several tables in the Hakka restaurant next to the hospital. He was so happy that he was willing to bleed so much.

After eating and resting for a while, Xiao Su said that Miyuki Fujiwara asked her to play ball together and asked Yang Ping to go with her.

They seem to have made an appointment a long time ago. The tennis clothes are inside the jacket, and the backpack for the racket is also brought.

Xiao Su usually works in the comprehensive orthopedic operating room, and only interacts with Mei Xue when she is performing surgery. Unexpectedly, they chat well, and Tang Fei, the three of them are like old friends.

Everyone rests for half an hour, and then goes to the court, etc., and can almost do strenuous exercise.

Song Zimo, Tang Fei and Xu Zhiliang went back to the department, Fatty went for a run, Xiao Wu was going home to accompany his wife, and Zhang Lin's wife was on duty. He packed a few bags, all of which were his wife's favorite food, and he had to deliver them in time.

Yang Ping, Takahashi, Xiaosu and Miyuki went to play tennis, but Yang Ping and Takahashi didn't change their clothes.

Xiao Su pulled Yang Ping: "Mei Xue and I have a good game, you can just be the audience."

Miyuki held Xiaosu's hand again: "China-Japan Women's Tennis Friendship Match."

Takahashi felt that he was superfluous, and followed behind, keeping a certain distance.

However, watching two tall beauties playing tennis is actually quite eye-catching.

The two of them even booked the venue of the hospital gymnasium in advance, so Yang Ping and Gao Qiao simply sat down beside them to discuss cooperation on the project.

The two stunning beauties were playing tennis, attracting a lot of attention from the side, and people looked over from time to time.

Both of them were very good, very fierce, and the game was evenly contested, and the score was very tight. It seemed that Xiao Su had met an evenly matched opponent.

Takahashi volunteered: "Dr. Yang, premature cell collapse is the problem facing all stem cell cultured organs. If it can be solved, this is an epoch-making progress. If Dr. Yang decides to set up this project, Takahashi requests cooperation. For the research group, I am the main person in charge and have enough right to speak."

"Cooperation can save us a lot of time. I don't want to reinvent the wheel, I just want to tackle the most critical difficulties." Yang Ping expressed his intention.

"If Dr. Yang is willing to cooperate with us, we can share all the early-stage technology, which will save Dr. Yang's time, and we will win together." Takahashi also thinks so.

At present, the University of Tokyo is at the forefront of this technology, but has encountered difficulties. Yang Ping analyzed all the current papers.

It is found that the recent papers of the University of Tokyo are all focused on the survival period of cells implanted in animals, and the extension time, one day, two days of increase, is very slow.

It shows that they have no technological breakthroughs for the time being, but continue to improve the original technology.

Cooperating with them will achieve twice the result with half the effort.

Scientific research is similar to navigation. The opening of a new route requires countless trials and errors, continuous corrections, and accumulation of data.

If you get the artifact of the system space laboratory in the future, you will also need a real laboratory to complete the experiment.

The data obtained in the system space laboratory can make you avoid detours in reality, and even complete it in one step, but you still need the real laboratory to repeat the whole experiment.

Therefore, it is beneficial and harmless to cooperate with these top international universities or hospitals.

The key is how to use and control these resources and be the leader in them. While scientific research insists on self-renewal, it must also be open and cooperative, Yang Ping thought.

Takahashi has seen Yang Ping's surgical skills and thinking ability with his own eyes, and he is convinced of Yang Ping's ability.

Now because Jinxue has established a friendship with Yang Ping, he has the advantage of being close to the water and is honored to cooperate with him.

In the future, when Yang Ping's scientific research becomes successful, it is estimated that the team that cooperates with Yang Ping will have to queue up, and it will be even more difficult for Takahashi to squeeze in.

Yang Ping watched the beauties play and thought: "Gaoqiao, let's cooperate and share the results."

"No problem, I will send an official email to the University of Tokyo in the evening to obtain the authorization to negotiate and sign a contract. We must be no worse than Duke University. Although we used stem cells to grow muscles later than them, we also completed it independently. , but the paper was published a little later, compared with them, we are more advanced in induction technology and micro-scaffolds, their animal survival time is three weeks, ours is six weeks."

Ever since he got to know Yang Ping, Takahashi has seen Yang Ping create miracles constantly. He firmly believes that if Yang Ping focuses on the field of stem cells, he will definitely be able to create miracles.

From a selfish point of view, Takahashi wants to get on this boat with the wind. As for the conditions of the laboratory, the existing technology may be very precious to others, but for people like Yang Ping, even if you don’t get along with him With cooperation, he can catch up by himself, it just takes a little longer.

At that time, if cooperation was proposed, Yang Ping probably had no interest at all. Now that cooperation is proposed, at least the existing technology can be used to help him save time.

The two beauties were drinking water after playing a few rounds, talking and laughing across the net, both of them were sweating profusely, the girls in motion are really cute.

After five rounds, Xiao Su was better and won three rounds.

Everyone packed up, Xiaosu and Miyuki went back to the dormitory to take a shower and change clothes, Yang Ping and Gaoqiao went to occupy a seat, and the few of them wanted to find a barbecue stand for supper.

Yang Ping also called out Song Zimo, Xu Zhiliang, Zhang Lin, Xiao Wu, and Fatty.

Zhang Lin is still in the pediatrics department, and works the night shift with his wife. Xiao Wu's home is near the hospital, and the two can arrive soon.

Song Zimo and Xu Zhiliang were practicing peeling grapes under a microscope, and they came out without hesitation when they heard that there was a midnight snack.

Everyone gathered together, Zhang Lin ordered a few cases of beer, except for Yang Ping and Song Zimo, all the men drank.

Several big men kept their majors in their mouths and continued the topic of the topic just now. Song Zimo and Xu Zhiliang also joined.

The three girls chatted together, and Miyuki Fujiwara was very good at Chinese. From time to time, she broke out funny Internet expressions, which made everyone laugh, and even took selfies with Xiaosu and Tang Fei and posted them on Moments.

Takahashi drank very frankly, as soon as he touched the cup, he would kill it immediately, and strictly followed Teacher Tang's instructions, no matter who he clinked with, the cup must be lowered by one centimeter.

"Go to Japan, I invite you to drink Wakayama Marina Beer!"

Takahashi thinks these Chinese friends are really kind. He wants to learn from Abe Nakamaro, and write an article, preferably a book, so that the Japanese can learn more about it.

Those girls chatted happily without knowing what to do. They seemed to be talking about interesting places in China. Miyuki found a good sister in China.

They don't care what the men here are talking about, they are clinking glasses of juice, and they meet to go horseback riding on the grasslands of Inner Mongolia, go to Tibet to see snow-capped mountains, and go to Hangzhou West Lake to wear Hanfu for photos.

Skewers with beer, so fucking cool!

Gao Qiao, Xu Zhiliang, Zhang Lin, Xiao Wu, Fatty, you have a cup, I have a cup, plus two jealous people, the atmosphere is very lively.

"Xiao Gao, okay, do it!" Zhang Lin immediately gave Gao Qiao a hand.

"Do it first and respect!" Takahashi didn't hesitate, turned over the cup, and did it, and he didn't refuse anyone who came.

After drinking, Takahashi got up and pointed to the direction of the bathroom: "Old irons! Wait for me, relax, come back and continue fighting."

Who taught him this, the old iron is called?

Zhang Lin, Xiao Wu and Fatty were stunned for a moment, this kid.

(End of this chapter)