godfather of surgery

Chapter 357

The regional competition of the Golden Knife Award is proceeding in an orderly manner, the competition is becoming more and more fierce, and the harsh scoring makes it more and more difficult to get a perfect score.

Yan Jiejun from Attachment [-] and Su Fengyu from Attachment [-] fell out of the full-score camp in the third batch of surgeries. They made the same mistake.

In a comminuted fracture of the lower end of the humerus, a young female patient was deducted points for the incorrect selection of sutures for cosmetic incision sutures.

In fact, joints used to be a contraindication for cosmetic sutures. The advantage of cosmetic sutures is that there are fewer scars, but the disadvantage is that they are not as firm as conventional intermittent sutures.

Joint surgery requires early rehabilitation training after surgery. Generally, rehabilitation training should start on the second day after surgery, so as to obtain satisfactory joint function.

The firmness of cosmetic sutures is poor, which cannot meet the needs of early rehabilitation training, and it is easy to cause incision dehiscence during activities.

Nowadays, cosmetic suturing techniques are getting better and better. If enough dermal tissue can be hooked with each stitch, early firmness can be achieved, and the original contraindications will become indications.

Yan Jiejun and Su Fengyu's cosmetic suture techniques are fine, but unfortunately they still don't have a comprehensive grasp of surgical suture techniques, they don't know enough about various sutures, and they made mistakes when choosing sutures.

For cosmetic sutures, they chose absorbable sutures, which is actually a mistake most surgeons make.

Many doctors even call absorbable thread cosmetic thread, which is completely wrong.

At present, the choice of sutures for cosmetic sutures must be non-absorbable slippery sutures, such as thin nylon sutures with needles, which need to be removed after surgery.

Absorbable sutures do not need to be removed, but they are used for skin sutures. During the absorption process, foreign body reactions and inflammatory reactions will occur, resulting in more obvious scars, which is contrary to the purpose of beauty treatment. Thin nylon sutures do not have this problem. After a few days , or demolished after ten days.

This is not a problem if it is performed in normal times, but in competition, we must strive for excellence.

After the third batch of operations, Song Zimo, Su Nanchen, Lin Hao, Chen Ge, and Cao Qian still maintained full marks.

The strength of the teams from other provinces in South China is still far behind that of Nandu Province, and there are no teams with perfect scores.

Lin Hao felt a sense of urgency now. After three rounds of surgery, Yang Ping's team did not get rid of them. They still tied with him for the first place in the South China Division.

Yang Ping is very clear about Song Zimo's level. With this first aid, he will have no opponents in the regional competition, and he will be able to sweep him for a while in the national competition.

Unfortunately, more than half of the surgeries in the national competition must be performed by the chief surgeon, and the final surgery must be performed by the chief surgeon himself.

So Yang Ping is not in a hurry now, as long as the points are not behind, he doesn't plan to show up for the time being, he hurry up to do more important things.

The project proposal for the research on cultivating human muscle in the stem cell laboratory has been written.

I spent all my time here these days, and the more than 100-page project proposal was placed on the desk, which made people's heads swell.

But there is no way, this big topic involves too many aspects.

Just like building a car, many factories need to cooperate, and it is impossible for one factory to make all the parts.

Yang Ping wants to focus on core technology. Although he intends to cooperate with Takahashi, he has no hope for the Japanese, which is just a branch line alternative.

Yang Ping's main line plan has been formed, and he needs to find several domestic partners.

The genetic laboratory of Nandu Medical University is the object of his planned cooperation to obtain or synthesize induced proteins.

In the topic of using stem cells to cultivate muscle cells, there are several core technologies, two of which have emerged, induced differentiation technology and micro-scaffold technology, and the third core technology in the future is cell structure stabilization technology.

Yang Ping searched for micro-stent technology for a long time, and finally found a new startup company in Pengcheng called Rubik's Cube New Material Company. Its 3D printing technology can achieve 15 micron printing. Although it is not enough, it is very promising.

This is a company founded by a group of overseas returnees. I don’t know if this team has the ability to complete the research and development of micro-stents. This is the only hope for domestic companies.

Only by finding these two partners can the project be completed. Yang Ping plans to find time to negotiate one by one.

If the University of Tokyo can cooperate with us and share technology, we can digest and absorb their technology and improve it, which will shorten a lot of time.

But this kind of hope is not great, Yang Ping is not a person with illusions.

Therefore, in the main line plan, we can only gnaw this bone from the beginning.

Overtaking on curves has never happened. Technology can only be done one step at a time. To overtake others, you can only rely on speed.

Scientific research funding is also a big problem, and the first phase of funding needs about 3000 million.

This investment is huge, depending on the scientific research fund applied for, even if it can be successful, it can be up to 100 million.

A fund of 100 million is a drop in the bucket. If the follow-up investment is included in this project, it will be in the billions.

If there is not enough funds, it will be difficult to run the project. These are very realistic problems, and now he feels that Xiao Su's words are very correct.

If one day, I can take out tens of billions of funds at will, I won't worry about this little money.

Someone knocked on the door, it should be that Song Zimo had finished the operation.

"You were supposed to write it, but you're going to have competition surgery. I've already finished it. This is my project proposal." Yang Ping pointed to a thick stack of documents on his desk.

Song Zimo browsed the overview: "Why didn't you write about the research funding?"

"It's not that I don't want to write. I can't write for the time being. The first phase needs 3000 million." Yang Ping laughed.

Song Zimo took a deep breath: "The first phase will cost tens of millions. This is a big project at the level of [-] million yuan. Are we a little—"

Yang Ping waved his hand: "Let's just do this project. I'll raise money for it."

Yang Ping felt that it was time to start, and he couldn't postpone it any longer.

Start now, and wait until you win the Golden Knife Award and get the reward from the System Space Laboratory. At that time, the project has already started work, and you can work hard yourself.

Now Yang Ping feels that if he really wants to do something, it will not work without money.

Huawei invests tens of billions in research and development funds every year, and it lasts for more than ten years before Kirin chips come out.

How can other companies have such courage and foresight, and this is an investment that cannot be seen.

Compared with this kind of arduous technology research and development, building a few houses can make a lot of money. Everyone likes the latter, and making money is fast and refreshing.

Duke University and the University of Tokyo have invested millions of dollars in this project, and this is all in the early stage.They plan to continue to invest hundreds of millions of dollars in research and development in this project.

"All kinds of scientific research funds, if you can get 100 million, you will be at the top. The money from the hospital, the Overseas Chinese Foundation, even if Director Han and Dean Xia agree, it is useless. The money belongs to the hospital, not to individuals. Take out tens of millions. It's impossible to come to do scientific research for you." Song Zimo was very worried.

Tens of millions is not a small amount. If it is a business, it may also attract venture capital. Who wants to do this kind of scientific research and lose money.

"I'll figure out how to deal with money." When Yang Ping had an idea, he had already thought of difficulties.

"3000 million. Some great professors may not even receive 3000 million in scientific research funding in their lifetime." Song Zimo felt that the money was too much.

"You can do the competition surgery with peace of mind. I'll take care of it. The subject must be done." Yang Ping could not doubt it.

"Okay, no matter what, I support you. No matter how much money you have, you can count. Let's find a way together." Song Zimo fully supported Yang Ping.

He was going to organize everyone to review today's operation, and explain to Yang Ping how to raise money together when he was free.

In the mobile WeChat group, Wei Danian's gene sequencing finally had results.

Some congenital diseases were all excluded, glucose 6-phosphatase deficiency, pyruvate dehydrogenase and carboxylase deficiency, fructose 1-bisphosphatase deficiency, oxidative phosphorylation deficiency, these known congenital causes of lactic acidosis Diseases did not exist in Wei Danian's body.

The most advanced genetic testing technology in the country was used, but it was still in vain.

Dr. Wen Yulin's gene sequencing report wrote dozens of pages, including detailed reports on the sequencing method, equipment used, and sequencing results.

Dr. Wen asked whether to continue to expand the sequencing, analyze some precursor molecules and metabolites, and even re-sequence the gene, which is a huge project.

Even gene sequencing has not found the problem, is there any need to continue?
Such a rare case is the most precious resource, and it would be a pity to give it up like this.

However, it is impossible for the genetic experiment of Nandu Medical University to concentrate all its energy on the genetic testing of Wei Danian, and there are still many subjects to be done.

If it wasn't for Su Nanchen's face, how could he accept such a favor.

Yang Ping suddenly remembered that his system recently had a case push function, and comprehensive medical activities can be carried out on the pushed cases.

He entered the system space, used the function of case push, constantly changed the keywords, and narrowed the scope of push. Finally, through precise push, he obtained a case that was very similar to Wei Danian.

Yang Ping conducted the most extensive inspection on this experimental body, including inspections of various laboratories and equipment.

But no clues were found, so they tried to perfect the patient's genetic sequencing.

The actual inspection methods are available in the system space, and there is no need to queue up for inspections in the system space, and the resources are all around the cases.

A miraculous thing happened. A few hours later, the fourth-generation gene sequencing technology was completed, and dozens of pages of gene sequencing reports came out.

After reading the genetic test report, the cause was still not found.

Yang Ping did gene sequencing a few more times, and this huge inspection cost him tens of thousands of points.

However, compared to simulated surgery, the consumption of these points can still be tolerated.

Finally, a report showed that there was a mutation in the ATP5F1D gene, and this gene was involved in the function of mitochondria. It was the mutation of this gene that caused problems in the metabolism of pyruvate and caused the accumulation of lactic acid.

"Can you continue to test, use the fourth-generation gene sequencing technology to focus on the ATP5F1D gene, and do it a few more times, there may be a mutation in the gene."

Yang Ping left a message in the group.

"I'm very sorry, the fourth-generation sequencing instrument is currently unavailable." Dr. Wen expressed regret that the project is also very busy recently.

Ten minutes later, Dr. Wen made an OK gesture.

"If we re-sequence comprehensively, we will not be able to free up resources at all. Only accurate detection of the ATP5F1D gene can be arranged."

If you rummaged through every household in the entire city to find a lost treasure, the difficulty can be imagined.

It's much easier to search only one house now.

Yang Ping used this case push function for the first time, and he wondered whether the inspection conducted in the system space was instructive in reality.

"We use the fourth-generation gene sequencing technology, and the results can be obtained in a few hours. We will start tomorrow." Dr. Wen added.

In fact, Su Nanchen saw the conversation in the group and called Lin Lan, who was willing to continue to help with testing.

Lin Lan is the director of the genetic laboratory of Nandu Medical University, a doctoral supervisor, and has another identity: Su Nanchen's future wife.

Lin Lan arranged it personally, and Wen Yulin will definitely do it. Lin Lan is her doctoral supervisor.

(End of this chapter)