godfather of surgery

Chapter 630 I Treat You

The study of the old academician Xiang of Nandu Medical University.

Old bookshelves circled the room, and the shelves were full of medical monographs.

On the old academician's desk, on the right is Yang Ping's project plan and experimental guidance on muscle cultivation with stem cells, and on the left is a pile of thick monographs, and he keeps pulling out new monographs from the bookshelf to read.

After reading a bunch of monographs, the old academician started to use the computer to look up papers again. Today, he has been in the study for almost eight hours. Even breakfast and Chinese food are brought in by his wife. This has been like this for the past few days, and his wife can't help but feel a little worried.

"It's time to move around, otherwise it is easy to get blood clots in the lower extremities." My wife couldn't help it, and reminded me gently at the door.

Usually, when the old man reads, the wife will not bother him at all. People in their 90s who sit still for several days in a row are really worried about some kind of venous thrombosis.

But the old academician didn't hear his wife's reminder at all, and continued to look up the papers, taking notes from time to time.

He was in the excitement period, completely forgetting how long he had been sitting.

"Whose project proposal is this? How many days have you been reading it? It's been sitting for eight or nine hours in a row today, no, I have to move around."

For the sake of the old man's health, my wife had no choice but to be violent, took away the pencil from Academician Xiang's hand, and then reached out to turn off the computer.

"Oh, it's eight hours again? Forgot, yes, walk around." The old academician looked at the furious wife, accompanied by a smiling face, and under the force of the lady, he finally stopped the work in hand, got up and ran around the room for a while.

"Whose project proposal is this, how many days have you been reading it?"

My wife is very curious.

When Academician Xiang heard his wife mentioning the project proposal, he stopped trotting, and suddenly became full of energy: "A young man's project proposal in Sanbo Hospital, this young man is very young. I have studied his project proposal for a few days, which is really rare. genius."

"It's that young surgeon that Xiao He often tells you about?" The old academician's wife also knew about this, and every time Professor He came to visit his tutor at home, he would mention this person.

It has been mentioned many times, so the old lady will naturally remember Yang Ping.

It's okay to be surprised by one achievement, but now this Yang Ping has many achievements that surprised the old academician.

The data that Yang Ping gave to Professor He were incomparably precious anatomical data. At that time, the old academician did not pay attention to them. Later, he studied them carefully one by one, and each of them could be called a heavyweight scientific research achievement. , also gave a lot of methods, these methods are brand new and state-of-the-art.

In particular, the recent subject of stem cell cultivation of muscle has made Academician Xiang acclaimed.

As for the field of stem cells, Academician Xiang is not very familiar with it, but in terms of anatomy, he is an academician, and he has devoted his whole life to researching this.

At that time, when he saw the micro-anatomy of muscles mentioned in the plan, the old academician's heart jumped. He had always wanted to propose this concept, but he felt immature, so he didn't say it out yet. Unexpectedly, this young man not only proposed this new concept, but also Also put into action.

Seeing the concept of microanatomy at that time, Academician Xiang was very curious about how young people came to realize this goal. It usually takes a few years to put forward a new concept and then realize it.

After reading the project proposal, Academician Xiang was so happy that he slapped the table. As soon as the new concept was proposed, the supporting theory immediately caught up. What a rapid pace of scientific research.

Academician Xiang studied for a few days and came to the conclusion that these experimental theories and methods are very mature, and they are not a hot-headed thing behind closed doors.

It takes a lot of courage and patience to start from the cellular level to build a micro-anatomy.

For single-layer cell slices, there are many unqualified cells in each slice, that is, cells that have been cut off. These cells must be judged by combining several slices before they can be restored.

For qualified cells, it is necessary to judge what kind of cells they are and how they are distributed.

Although artificial intelligence can be used to replicate recognition, it is very difficult to develop a recognition engine.

So, what a complex project.

But the young people not only started the project, but also came up with effective methods, and they have already taken the first step and are moving forward step by step.

"I won't come back for dinner tonight." The old academician reported to his wife after answering the phone call.

The madam was surprised again, the old man rarely ate out for decades, why did he eat out today, and he actually had a social event?
"Xiao Yang is coming to the Digital Medicine Laboratory of Southern Metropolis Medical University today. I greeted Xiao He. When Xiao Yang arrives, he will notify me. Let's have dinner and meet each other in the evening. I have always wanted to meet this young man." The old academician It turned out that I was going to have dinner with Professor He and Yang Ping in the evening.

"This little Yang, you haven't met him yet? Then you recommended him to Principal Rao? At that time, you made an exception to promote him as an associate professor?" The old lady thought they knew each other very well, but they had never even met in person.

The old academician was a little unhappy about his wife's questioning: "He made an exception for the promotion of an associate professor. I not only strongly recommended it in front of President Rao, but also personally lobbied the review committee members. It was because his academic performance qualified him to become an associate professor. It didn't matter whether I met him or not. .”

"Okay, let's see that you are so anxious, may I just say casually, you have a better vision, come back early after dinner."

The old lady reminded with a smile.

At this time, the old academician's phone rang, and it was from Professor He. When the old academician heard it, Xiao Yang was almost here.

"I have to wait in advance. Young people are short on time, unlike us old men."

The old academician looked excited, and hurriedly prepared to go out.
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Nandu Medical University Digital Medicine Laboratory, Professor He's office.

Academician Xiang and Professor He are drinking tea and chatting.

In order not to interfere with the work of young people, Academician Xiang only occasionally comes to the laboratory to ask about the progress of the research.

I came to the laboratory today entirely to meet Yang Ping.

"Teacher, you——Xiao Yang wanted to visit you a long time ago, but he was afraid of disturbing your quietness. If you want to see him, just tell me a word, and I will take him to visit you." Professor He did not expect the teacher to personally Come to the lab to wait for Yang Ping, I feel so embarrassed.

Academician Xiang chuckled and waved his hand: "It doesn't matter, my old man has free time, and you young people are all busy. Anyway, I also want to come over to see your progress in micromuscular anatomy."

"We have already begun to try to slice the muscles of the cadaver specimens, and then check whether the slices are qualified. If the pass rate reaches the standard, we will start large-scale slices. The artificial intelligence cooperation with BD company has already begun. We will introduce artificial intelligence to the sliced ​​species. Cells make judgments, and the digital engine is still under development, so that in the future, we will not rely on manpower for similar projects, but use artificial intelligence to make judgments." Professor He reported the progress of the project, which is just beginning.

Academician Xiang gave some suggestions: "Due to the irregular arrangement of cells, it is impossible to achieve a true monolayer cell slice, but it is possible to have many complete monolayer cells in each layer. Those damaged cells, Relying on the integration of multiple slices to restore them is a technical difficulty, but a solution has been proposed in the experimental guidance."

"Yes, Professor Yang has already proposed a solution to superimpose these slices individually to restore the shape of the damaged cells."

Professor He has read the experimental guide countless times, and every time he reads it, he is unbelievable. It seems that Yang Ping has considered all the difficulties he can think of and proposed solutions.

There are only a handful of digital human teams in the country. In terms of experience, my own team is definitely the most abundant.

No one can surpass Professor He in terms of micron-level human tissue slices, how to achieve single-layer cell level, and the digital humans they made at that time were at the forefront of the world.

However, the method in the experimental guidance in front of me is obviously much more advanced than my own method, and it is easier to obtain qualified slices, and the method of using slices to build three-dimensional digital muscles is still more advanced than my own method in the experimental guidance.

Where are these methods obtained from?
If it is borrowed from others, it is impossible for Professor He not to know that there is such an advanced method.

There is only one possibility, Professor Yang came up with it himself?
If you can figure it out yourself, this kind of talent is a bit scary.

While Professor He was contemplating, Academician Xiang said slowly:
"He can extract theories from limited experience and then apply the theories. This is a very remarkable inductive and deductive ability, so it is a kind of luck for you to cooperate with him. No matter whether the project can be successful or not, you will be able to Learning the method of constructing the microanatomy of the whole human body will push the digital human to a new realm."

Ever since Professor He talked about Yang Ping, Mr. Xiang was very curious, so he carefully studied the data and methods provided by Yang Ping, and found that it was not simple, and the data and methods given were extremely advanced.

And it is impossible for Yang Ping to have so much time for anatomical research, so Academician Xiang believes that this young man's ability to summarize is astonishing.

So Academician Xiang began to pay attention to this young man, and then read his spinal external fixator project, the latest stem cell project book, the old academician was very excited, and discovered with his keen academic vision that this young man is a scientific research genius.

Not only has strong surgical ability, but also such a strong scientific research, this is really a rare talent.

So eager to see Yang Ping, when he received a call from Professor He, he hurried over.

"Why did he put the research on the repair of peripheral nerve injury into this topic, which should have little to do with this topic?" Since the teacher liked to discuss this topic, Professor He followed up.

"I also pondered for a long time before I figured it out. He looks at this issue from a combination of several majors, so he has a higher vision than us. His thinking is very clear. To clone an organ, whether it is directional cultivation or 3D printing, the prerequisite is Find out the microanatomy of the organ, otherwise no matter which method will be successful, secondly, if the organ is really cloned, he also knows where the biggest obstacle is in the application? He will study this issue together in advance, so this The subject is huge."

Academician Xiang sees problems better than others. He can see many deep-seated things in this project proposal and experimental guidance.

"You mean that he listed nerves as a separate research project for future transplantation preparations?" The teacher reminded that Professor He probably knew the purpose.

"That's right, no matter which method is used, if the muscles are copied by us, then the biggest problem facing the transplantation to the human body is the problem of nerve connection. The problem of blood vessels is easy to solve. Once the anastomosis is completed, blood can flow through. The nerves are different. , it connects, it does not anastomose at the fracture, but grows from the proximal end to the distal end, so the nerve must be studied more thoroughly, if you can’t get your muscles innervated, it’s meaningless.” Academician Xiang said to Yang Ping’s project The layout has been thoroughly studied.

"So that's it. He's going to get through all the steps at once. From this point of view, this subject is indeed a bit grand." Professor He felt a sense of awe towards this subject.

"He proposed two solutions. First, when cloning muscles in the future, instead of copying the complete nerve at the position of the original nerve, the nerve sheath is copied, and a layer of substances that induce nerve growth is arranged on the inner surface of the sheath. In this way, after the muscle is transplanted, the nerve sheath is connected to the nerve of the human body, and under the guidance of the inducing substance, the nerve grows along the sheath until it reaches the end."

Professor He finally kept up with the teacher's rhythm: "He bypassed the difficulty of nerve repair and found another way?"

"Not only opened up another way, he opened up a second way!" The old academician took it easy.

He has to teach himself this doctor well today.

"There is another way of thinking?" Professor He was puzzled, and there was nothing to say.

The old academician was quite proud: "That's because you are not in charge of this project, so your plan here did not mention it. If I am not wrong, the person in charge of the research and development of bio-3D printing technology must have research on tissue damage bio-connection technology. "

"Biological connection technology?"

Professor He was even more confused.

"This is the second, which is to use stem cells to cultivate the cells of each layer of the nerve, and then use the micro-3D printing technology to connect the original cells of the nerve, but this requires the micro-printing of the 3D printing technology to be very good. If you don't believe me, you can ask me later. , he will definitely have this project.” The old academician became more and more excited as he talked, and he was proud of his guess.

The nerve cannot be repaired after rupture because it does not heal. If it can be repaired at the cellular level to restore it, this is naturally a better method, but it is much more difficult than the previous idea.

Professor He was very ashamed: "Why didn't I see so many things?"

Academician Xiang sighed and said: "That's because you are limited by your major and focus on anatomical research, but I have time over the years and have read many books in other majors, so my thinking is broader."

"Why hasn't Xiao Yang arrived yet?" The old academician was a little anxious.

Professor He said: "It's a bit of a traffic jam."

"Have you already decided where to eat?"

"It's settled!"

"I'm here today for a treat."

"How about that?"

"It's okay, it's settled, I'll treat you."

(End of this chapter)