godfather of surgery

Chapter 765 The rice-barrel maker

The expert review of the "Science" journal generally has two to three peer experts. According to the regulations, the editor-in-chief Lewis will also recommend the article to another expert-Professor Fukunaga Junzan of the University of Tokyo, Japan. He is one of the world's three leading experts in the field of stem cells. One of the top experts, these three papers involving skin expansion technology are essentially research in the field of stem cells or cloning.

According to the normal review process, Professor Fukunaga would not read these three papers so quickly, because there are still many manuscripts ranked ahead of Yang Ping's manuscript.

Reviewing manuscripts is a brain-consuming task. Professor Fukunaga is always meticulous and reviews each article slowly and in order.

After Yang Ping's three papers were strongly recommended by Maninstein, in order to strictly complete the process, Lewis had to re-send an urgent email to urge Professor Fukunaga to review the manuscript as soon as possible, and he also included Maninstein's review comments. Attached to the urgent email.

Professor Fukunaga Junshan's life is very regular. He never participates in any social activities after get off work. Instead, he stays at home and reads books or journal articles.

His house in Tokyo is not very big, only about 90 square meters. Of these 90 square meters, his study room occupies nearly [-] square meters. This shows how much Professor Fukunaga is a person who loves reading. Reading occupies the main part of his life. part.

After dinner, he habitually opened his email to see if there were any new emails in it, because Professor Fukunaga maintained close communication with several major stem cell laboratories in the world. The main way of communication was through email, and processing emails was his daily job. Indispensable content.

Suddenly an eye-catching urgent email mark appeared in front of him, and he immediately opened the email. It was an urgent review manuscript for the journal "Science".

Professor Fukunaga opened the email and initially browsed the article to grasp the general meaning of the article.

It seems that the author chose a single-blind review. Professor Fukunaga could see the signatures of the authors of the three papers, and there was a familiar Chinese name in them that caught Professor Fukunaga's attention - Tang Shun.

This name is very high and belongs to the main researcher. Professor Fukunaga has a proud Chinese doctoral student also named Tang Shun. There are many people with the same name. Could this be just the same name?

Professor Fukunaga’s eyes moved to the author’s institution—Sanbo Hospital Affiliated to Nandu Medical University in China.

Combining the name with the unit, yes, it is this hospital, and my own doctor, Tang Shun, works in this hospital.

So this Tang Shun is his student. This is the first project he participated in after returning to China, and it is also the first paper he published as the main author.

When Tang Shun graduated, Professor Fukunaga repeatedly asked Tang Shun to stay and work in the Stem Cell Laboratory of the University of Tokyo. However, Tang Shun refused the tutor's good intentions and insisted on returning to China.

After returning to China, Tang Shun told his supervisor about his workplace. Professor Fukunaga was furious. An outstanding doctorate in stem cells could go to the United States even if he did not stay at the University of Tokyo. If he did not go to the United States, he must return to China. The Chinese Academy of Sciences was the best. Good choice.

But this guy actually chose a hospital, a hospital whose name Professor Fukunaga had never heard of. Professor Fukunaga didn't understand Tang Shun's behavior very much. It was impossible for a researcher in basic medicine to achieve anything in the hospital. Professor Fukunaga thought Tang Shun was in the hospital. Give up your future.

Tang Shun didn't know how to explain it, because no matter how he explained it, Fuyong would not change his opinion.

But Tang Shun was very determined in his choice. He said goodbye to his teacher and returned to China. He called Professor Fukunaga. Professor Fukunaga was furious and did not want to answer his call at all. In this way, the teacher and student temporarily lost contact because of this incident.

When Yang Ping submitted his paper this time, it was Tang Shun's idea to conduct a single-blind review. He knew that these three papers would definitely be transferred to Professor Fukunaga.

This was a student's paper. Professor Fukunaga was very interested. He carefully studied the three papers. Of course, like Maninstein, he spent an entire night.

In order to understand the many new concepts and theories mentioned in the paper, Professor Fukunaga needs to read it repeatedly, and some passages need to be carefully considered for accurate understanding.

After reading, Professor Fukunaga leaned back in his chair and could not calm down for a long time.

The academic achievements of these three papers are far beyond my own. They have accomplished the goal that I have always wanted to complete but have not yet achieved - cloning organs using somatic cells or cloning organs using mature somatic cells.

Although this organ is just skin, and skin is the simplest organ in structure, with only two layers of different thicknesses: dermis and epidermis, no matter what, they did use somatic cells to clone skin.

This is a great start, which will open a new era of cloning, which is as significant in the history of science as cloning sheep.

After Professor Fukunaga calmed down, he excitedly grabbed his cell phone and dialed Tang Shun's cell phone, regardless of some of the regulations regarding manuscript review.

"Tang Shunjun——"

The Japanese professor was a little excited and added the character "君" at the end.

"Mr. Fukunaga!"

Tang Shun was very happy to receive a call from his mentor. He did not expect that his mentor would take the initiative to call. This showed that his mentor was relieved about his job choice.

Professor Fukunaga took another calm breath and said: "Congratulations on your breakthrough in cloning technology, it's amazing! You can actually use skin directly as the amplification source, and then perform clonal amplification. This is a true local cloning technology. At the beginning, this is true human single organ cloning technology. You can clone skin without resorting to embryonic technology. This is a great start."

"Thank you Mr. Fukunaga, I'm just an assistant."

Tang Shun was not humble. Indeed, he was just an assistant and only conducted experiments according to Yang Ping's A4 paper. He did not expect that the experiment would be a success.

"No, it's amazing to be able to participate in this experiment, not to mention being the main researcher. You make me proud." Professor Fukunaga said with enthusiasm.

Even the assistant is very impressive. This must be the reason why Tang Shun went to Sanbo Hospital in China. He has only been back to China for a short time, less than three months, and he has actually made such an amazing achievement.

Professor Fukunaga asked curiously: "I'm very surprised. I've never heard Professor Yang Ping's name before?"

Because the number one signature is Yang Ping.

"He is my current professor, a genius doctor. His talent is beyond anyone's imagination. He is not a researcher in the field of stem cells, but his project requires the use of stem cell technology, so I returned to China to follow him."

Tang Shun wanted Professor Fuyong to briefly introduce Yang Ping's situation.

"Not a researcher in the field of stem cells?" Professor Fukunaga was very surprised that a doctor who was not an expert in this field could actually achieve such remarkable results.

"Is he a clinician? Or a basic medical researcher?" Professor Fukunaga was very interested in learning more about Yang Ping's situation.

Tang Shun said: "He is a clinician and a surgeon, not a basic researcher."

Professor Fukunaga took a deep breath, a surgeon?Regardless of his educational background or knowledge, it should not have much to do with stem cells, but judging from the paper, he is obviously a top researcher in this field.

"How long have you been conducting research on your project?" Professor Fukunaga asked.

"It officially started after I returned to China."

After hearing this, Professor Fukunaga couldn't believe how it was possible to achieve such results in less than three months.

Almost all the world's top laboratories have encountered bottlenecks on this kind of subject. According to Professor Fukunaga's estimation, it will take at least ten years for top teams in Japan and the United States, right?

And things like scientific research are uncertain. Sometimes it is difficult to make breakthroughs in decades, let alone ten years. It is estimated that it will take ten years for everything to go smoothly.

Now Tang Shun says it will take less than three months. How is that possible?
Is it only open for three months, but the preliminary experiments have been going on for a long time?Tang Shun played a key role in the breakthrough after returning to China?

If so, Tang Shun must be the world's tallest being in the field of stem cells in the future.

No matter how long the experiment lasted, the results were already in front of him. Professor Fukunaga couldn't wait to replicate Yang Ping's experiment: "If I want to replicate this experiment, do I need you to provide induction factors?"

The paper does not mention the genetic code for this amplification technology. Why can skin be amplified?The key is that the induction factors work, but how the induction factors work is not specifically mentioned in the paper. What is the principle of the added induction factors, their formula, what is the specific ratio, and what is the function of each factor? , how to obtain these factors, etc., are not mentioned in the paper.

Whether the experimenter only knew the results and had not yet figured out the principle, or they deliberately kept it secret, the latter is obviously more reasonable. The experimenter did not want to leak the key information of the induction factor. If you want to replicate this experiment, you can only obtain the induction factor from the original author for the time being. .

It was not convenient for Professor Fukunaga to continue asking Tang Shun, so he directly asked Tang Shun for the induction factor.

"Yes, that's right, because for some reasons, we cannot disclose the acquisition method and specific formula of the induction factor for the time being. We can provide the induction biological agent for free to any team that needs to replicate the experiment."

Tang Shun also knows that only experiments that can be copied by others will be recognized. Experiments that cannot be copied are meaningless and will be regarded as fraud. This is the basic principle of scientific research.

However, the specific information of the induction factor is very critical and involves the next step of the experiment. For the safety of the next step of the experiment, it must be kept confidential.

"Tang Shunjun, I'm so excited, okay, how can I get your induction factor, or I should come to China." Professor Fukunong can't wait to start the experiment now.

Tang Shun asked the Japanese professor to calm down on the phone: "Professor Fukunaga, you don't have to come in person, I will send it to you, or you can ask Miss Fukunaga Masako to come."

"Okay, I'll let Masako go for a run, please, Tang Shunjun." Professor Fukunaga was very happy.

Fukunaga Masako, Tang Shun's senior sister, a young professor at the University of Tokyo, Professor Fukunaga's daughter, Tang Shun's number one girlfriend on WeChat, of course, she is in her early thirties, but she has always been single.
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The famous "Science" journal was founded in 1880 by inventor King Edison with an investment of US$1. 14 years later, in 1894, it became the official publication of the American Association for the Advancement of Science, the largest scientific group in the United States. 51 issues, with a global circulation of more than 150 million copies.

The British journal "Nature" is a commercial journal, while the American "Science" is an academic journal. Of course, this difference is not important because they are both top journals.

In Washington, D.C., the headquarters of the journal Science is brightly lit.

Editor-in-Chief Lewis adopted Maninstein's suggestion. He is working overtime to rearrange the next issue of the journal, which means that all work must be overturned and restarted, and the workload is huge.

Colleagues in the editorial department complained. Some of them had been working for only a few years, and some had been working for more than [-] years. They had never experienced this kind of thing. They published three articles for the same person at once, and they also had to give a cover article. What is even more outrageous is the rush to publish, which involves re-arranging journals that have already been typed out overtime.

"Boss, what happened? I have applied for leave. You are trampling on labor rights." Someone was typing on the keyboard reluctantly.

Then, many people began to protest against this inhumane overtime behavior.

Lewis walked between the rows. He knew that he could not shut up these guys, so he said coldly: "This is the masterpiece of that nasty German guy - Maninstein. If necessary, I can give him his phone number." His email address is posted on the glass door, and you are welcome to ask him questions at any time.”

When he heard that everything was Maninstein's idea, the guy who shouted the loudest gave up the fight: "Okay, we admit defeat."

Those followers actually all shut up and worked overtime on the keyboard to rearrange the content of the journal.

Because Maninstein is like a god in their hearts, and this guy doesn't play by common sense, and his thoughts and behaviors are extremely weird. They can only stay away from such a person.

Even if these people do file a labor complaint or sue, they believe that Maninstein has a hundred legal ways to dishearten the protesters and not only get nothing, but also lose their jobs.

Of course they were just joking and didn't really mean to protest Lewis.

Because of the ethical issues of experiments, Maninstein was bombarded by various "righteous people" in Europe and the United States. Whether in Europe or the United States, Maninstein did not need a lawyer or an assistant. He dealt with all doubts by himself. After many rounds of article debates and on-site debates.

In the end, these "righteous people" were not only defeated, but also gave people all over the world the impression that these guys were all uneducated, ignorant, and ignorant bastards.

Therefore, there is a famous saying in academic circles - "If you don't want to become a well-known loser, don't mess with Maninstein."

Maninstein also received a domineering nickname - the rice-barrel maker.

(End of this chapter)