It's not that hard to open a hospital in another world, right?

Chapter 470 The biggest difficulty in the development of smallpox vaccine

With the hospital in place and manpower in place, Gretel rolled up his sleeves and started working.

The front yard, that is, the outpatient department, is still sluggish and empty.There are only a dozen patients who come to the clinic every day, and the five healers who sit in the clinic are so idle that one Buddha is born and two Buddhas ascend to heaven. I wish everyone could have a cat:

It’s not about petting the cat to relieve irritability, the main thing is that you can throw a ball of wool to the cat, let it mess up and then pick it up and tidy it up. You can find something to do for yourself...

In the backyard, that is, the research department, work is proceeding in an orderly manner.The things that troubled Leon Carlos for half a year are almost no problem for Gretel:
"You try freezing, drying, and freeze-drying. The three methods are applied alternately. The freezing temperature is from -20 degrees to -10 degrees, and 2 degrees to 10 degrees. Each degree is regarded as a grid."

Without changing his face, he reported a long list without even thinking about it.Well, how should vaccines be stored?I don't know, I haven't learned it, and it's not in the textbook.This is not the scope of applied medicine. Making vaccines is the job of bioengineering next door...

Fortunately, during the epidemic before crossing over, Gretel had heard about it, as if there were several preservation temperatures.Relying on this scrap of knowledge, Gretel talked eloquently, and seemed quite capable of bluffing people.

Well, left and right he is the big boss, just give directions.To do experiments or something, someone will naturally run errands to do it!
Leon Carlos scribbled his notes, barely keeping up with his speed.As for how to achieve Gretel's request, adjusting the magic circle can naturally be done, but it is a bit of a waste of budget...

"For drying, don't use heat. You can use natural drying, dehumidifiers, or use magic to drain the water." Gretel's instructions continued:
"I remember... there is a magic called [Touch of Thirst]?"

"That's right, first-order necromancer magic." Carlos came alive.This magic, through touch, can make living things lose water quickly and in large quantities, and fall into a state of dehydration.Although there are quite a lot of restrictions and the price/performance ratio is not high, it seems to be just right for vaccine dehydration?
"However, I don't know how to do this magic..."

He was a little ashamed.Although he is a necromancer and has advanced to a full-time mage, he is only a college student—in other words, he has no direct mentor to guide him, and his grandma doesn't love his uncle or uncle.

Some of the most common necromancy magics, such as fighting the undead (yes, the introductory trick of the necromancy system is fighting the undead, which can be described as a model of [I kill myself]), fatigue touch, cold touch, weakening ray, You can still learn in college. [Touch of Thirst] This niche magic...

"Oh, I'll give you the information later."

Gretel responded nonchalantly.The Horn of Thunder is rich in storage. The Archmage Carlisle threw him countless spell models before, and there was [Touch of Thirst] in it.

A mere first-order magic, taught to the magician in the mage tower, I guess the school would not care...

As for freeze-drying, they have done it before when they made penicillin, and they have ready-made experience, and now they just copy it.

Carlos led the way.Gretel sat alone at the desk, resting his chin and thinking:
How to verify the effectiveness of the vaccine made?

If it is replaced by cholera vaccine or plague vaccine, it is very simple, and a large number of animals can be used for experiments.But the smallpox vaccine is not good. Smallpox is notoriously only infects humans.What kind of mouse, rabbit, dog, pig, nothing can be used...

Gretel began to scratch his scalp.After grabbing for a while, the oak stick rolled up the [Endless Ink Pen] and jumped out of his pocket, and began to write:
Technical route 1: Use cattle as verification objects. 20 freezing temperatures, 10 vaccines per group, storage time 2 days, 3 days, 4 days, 15 days, 30 days.A total of... 1000 cattle? !
Are there so many cattle around Nevis?How much budget do you need to get so many cows?
Technical route 2: Use primates as verification objects.The same grouping method, need... 1000 monkeys?
The oak stick shook.Press down on the [Endless Ink Pen] to draw a deep and long mark on this technical route.

Technical route 3: Use human beings as verification objects...

Dr. Jenner did the same thing back then, directly vaccinating people with the vaccinia vaccine, and then vaccinating people with the human pox vaccine a few months later.If the vaccination against human pox is successful, it means that vaccinia has not produced protection; if the vaccination against human pox fails, it means that the vaccinia vaccine is successful.

The advantage of this route is that there is no shortage of people in Nevis City. If you want to find 1000 people as experimental subjects, you are absolutely not afraid of not being able to find them; the disadvantage is that...

Gretel found sadly that he still had a little social fear.It is easy for him to sit in a hospital and treat 1000 patients, but it is easy for him to go to the street to arrest 1000 normal people and persuade them to be the experimental subjects for vaccinia vaccination...

Just thinking about it, I thought, forget it, it's better to kill him.

As a doctor, a doctor in a public tertiary hospital and an emergency doctor in a tertiary hospital, I have never worried about too many patients, not too few patients.How to attract patients, he has no experience!
Woo, how did Dr. Jenner find so many test items back then?

Gretel struggled to recall, and sadly found that Dr. Jenner seemed to have done only a dozen people back then.So why do I need 1000 people?Is there something wrong with my experimental design, or my requirements are too high?
Hey, I was too anxious before, I vaccinated all the apprentices and nurses, and there are no experimental subjects...

Gretel hugged his head, groaned, and slammed his forehead on the desk.With a bang, Aniviya who pushed the door and came in was startled:
"Sir, what's the matter with you?"

"Who shall I inoculate with cowpox..." Gretel rested his forehead on the edge of the table, moaning.Aniviya stepped forward holding the tray, glanced at the manuscript on the table, and laughed:
"1000 people? Sir, it's very easy to get 1000 people. In which month can we get less than [-] patients in our treatment center at the port?"

Gretel scrambled to his feet.

Yup!

Get the reputation of the clinic out!

Let the surrounding people feel that this is a reliable place!
Gretel snatched the pen from the root of the oak stick and began to write.Once the idea is opened, the ways to find people become rich and colorful:

1. Build the reputation of the clinic and attract more patients.This is the right way, if you manage well, you will have unlimited potential;

2. Go to the surrounding area to send the doctor to the countryside, and vaccinate people by the way.It must be said that wearing a linen robe, holding an oak staff, and riding Apa, he is still full of momentum, which is easy to believe.Find 20 subjects in a village, walk 50 villages, and the task is completed;

3. Talk to the city hall and ask some prisoners for experiments.The city hall may not necessarily buy it, it may first communicate with the public health department, or play the banner of teachers;
4. Ask the surrounding lords for help, they will lead the people, and they will produce vaccines...

Although 1000 people are needed for the verification of the vaccinia vaccine, these people do not have to come at the same time: considering that the later vaccination with variola needs to be isolated and observed, in fact, only 20 to 40 people are needed for each batch.If there are more, the hospital's capacity to receive patients will not be able to handle it.

In this way, the pressure is actually not much.

"Annivea! Let's go to the front for a consultation!"

The addition of Gretel, however, did not initially make things better.For the door-to-door of the poor, experienced healers will give some medicine for mild cases, and throw a healing technique for severe cases, and usually solve the problem within 10 minutes.Only Gretel, 10 minutes is not enough for him to check:

"What's your name, sir?"

"age?"

"Where are you uncomfortable?"

"Stand up and let me see... Hey, you took off your coat and all those metal ornaments!"

"Okay, lie down, lift up your clothes, and let me take a look..."

Inspection, interrogation, auscultation, palpation. X-ray, B-ultrasound, electrocardiogram.The time to collect the patient's condition is three times longer than the treatment time.In this way, the final answer is mostly:
"Sir, take this pack of medicine..."

"Sir, I will give you a healing technique..."

Just, what a waste of time.

And rob patients!

The priests who worked with him looked sideways.Mr. Gretel Nordmark, although you are our employer, can you stop stealing our jobs?
We also need to accumulate treatment experience to advance!
Because the amount of treatment here is too small, we have already divided the work, and everyone only came for half a day!
Mark Saren, the third-level priest of the God of War Temple, rolled up his sleeves, carried the treatment table on his shoulders, and silently moved it to the gate.

Hannah, the second-level pastor of the God of Nature Church, immediately followed up.She didn't even have to ask for help, she urged the animals and plants to roll up the two table legs, and then lifted one edge of the table by herself, moving the treatment table to the other side of the door.

Gretel: "..."

As for?As for this to me?Didn't I just spend a little more time checking?I didn't leave you guys to work overtime!

snort!If you have the ability, you can continue to grab it!If you have the ability, don't run into intractable diseases that can't be solved!
Gretel made circles in his heart angrily.However, intractable diseases came soon——Mark came to him with a face full of embarrassment and called him:

"Master Nordmark, come over and take a look? I have treated this patient more than once, and it keeps recurring!"

Gretel got up and went out.When the visitor saw him, he piled up a smiling face, his chubby face overflowed to both sides, and his eyes were narrowed:

"Reverend Nordmark!—do you remember me?"

... To be honest, the face is a bit familiar, but I can't remember the name.Gretel swiped from top to bottom, from bottom to top, and stopped at his obviously swollen finger joints, suddenly realizing:

"Oh... you're the one... I cured you of gout! How are you doing now? Do your fingers and toes still hurt? Do you still eat sea fish and wine?"

"Don't dare to eat, don't dare to eat." The businessman nodded and bowed, with a smile on his face.He helped the white-haired old man into Gretel's consulting room, and sat down across his desk:
"My father coughed up blood again...I found more than one pastor, all of them were cured at the time, and then relapsed after two months...Pastor Nordmark, can you show me?"

****
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　I checked the relevant papers on vaccine storage and transportation temperature, basically all of them are veterinary vaccines... despair...

　　Thanks to @暮然先头^O^ for the reward of 100 starting coins

　　
　
(End of this chapter)