Hand rubbing nuclear fusion live in the wilderness

Chapter 555 Studying Cell Telomere Modifiers

After the second year, the outer space exploration mission is almost completed.

On the whole, the branch chain tasks have basically been completed, and there is still one main task and one branch chain task in progress, but he doesn't need to worry about that anymore.

Whether it is establishing a base on an alien planet or collecting data and information from an alien system, there is no need for other people to take care of it. The two artificial intelligences Xiao Qi and Xiao Ling will handle it well.

In the last year, Won did not idle, and he began to study life on Mars and cell telomere modifiers.

The former is pure curiosity about what life on Mars is like.

The latter is the extension of lifespan. It has been more than eight years since he got this system. He is no longer the green boy who just graduated, but now he has become a salted fish uncle in his early thirties.

One life is only a hundred years, but who doesn't want to live for a while?
From ancient times to the present, longevity has been an eternal dream.

Don't you see what those emperors and rich people did to prolong their lifespan. In ancient times, Qin Shihuang went overseas to search for elixir, and now there are various capital rich people investing in life research.

Is everything you do just to live a few more days?
In the biological research room in the center of the base, Han Yuan flipped through the industrial equipment application knowledge information in his mind, and then imported some equipment knowledge for biological research through the virtual helmet, and then handed it over to the CNC center for processing.

With complete manufacturing information, it is not difficult and it does not take long for an intelligent CNC center to cooperate with a large 3D printing factory to process these devices.

The remaining cell telomere modifiers were taken out by Won, and began to be analyzed and researched through various equipment.

A telomere modifying agent can be used by three people, the first third of which was injected into an elderly bonobo by Won for biological experiments.

The changes were visible to the naked eye. The bonobo who was on the verge of death not only did not die, but survived rejuvenated.

Han Won has been observing this bonobo for several years, and as of now, this bonobo is still alive and well, and its physical condition is quite young.

If there's a downside, it's that the bonobo has yet to have offspring.

This is Won's more worrying point, worrying that this may be a side effect of cell telomere modifiers.

Of course, it is also possible that the bonobo had lost its ability to reproduce before the injection of the telomere modifier.

After all, no matter how powerful the cell telomere modifying agent is, its main function is only to repair cell telomeres and prolong life. What has been missing may not necessarily be restored.

It's like injecting this thing into a person with a broken hand, and the missing hand may not grow back.

As for the second third, Won gave a part of the special operations team. At that time, he didn't have time to study this thing, so he could only ask the above to study it.

But so far, the research on cell telomere modifiers has not made much progress.

It may be the reason of the equipment, or it may be that there are not enough talents in this field. Anyway, the research is not progressing smoothly.

...

Part of the components in the cell telomere modifying agent has been analyzed, but only a part, and there are still some mysterious substances that cannot be analyzed.

This also led to the abort of the research and development and replication plan for cell telomere modifiers.

In the biological laboratory, Won accurately divides one-third of the cell telomere modifier, and the remaining small part is divided into several parts and sent to different equipment for analysis.

Spectral data analyzers, chemiluminescent technology detectors, chromatographic analyzers, electrophoresis devices, and various equipment that can assist in the analysis of materials and drugs are in operation, and various information such as components, structures, and material forms in cell telomere modifiers are collected. Analyze it.

"Master, the component analysis data of cell telomere modifiers are out."

Xiao Ling's voice sounded in the biological laboratory, and a virtual projection screen was unfolded in front of Han Yuan's eyes simultaneously, and various data and ingredients were listed on it.

Won slid the virtual projection. Some of the analyzed data are existing materials and substances, and the existing names are used for naming.

For example, one of the key substances is called 'ribonucleotide long-chain molecule via phosphodiester bond'.

This name sounds very long, and most people may be a little confused after seeing it, and don't know what it is, but if you put it another way, most people will know what it is.

In biology, ribonucleotides have another name for long-chain molecules via phosphodiester bonds: "RNA!"

That's right, ribonucleic acid, the most common noun in junior high school biology, is a genetic information carrier that exists in biological cells and some viruses and viroids. It is composed of phosphate, ribose and bases. The key point is bases.

There are mainly 4 kinds of bases in RNA, namely A (adenine), G (guanine), C (cytidine), U (uridine), but their combination will produce many different types of RNA, The functions and distributions of these RNAs also vary.

There are many types of RNA, but in general, there are three types of RNA in most organisms.

The first is mRNA, which contains four nucleotides of A, U, G, and C, which is responsible for transmitting genetic information and directly directing the synthesis of amino acid proteins.

The second type is tRNA, each tRNA has an "anticode" composed of three nucleotides; this anticode can be paired with the corresponding code on the mRNA according to the principle of base pairing.

Therefore, it is a transport tool, responsible for transporting amino acids, interpreting mRNA genetic codes, etc. during protein synthesis.

The third type is rRNA, which is the most abundant of the three types of RNA, accounting for 80% to 85% of the total RNA in the cell, and together with a variety of protein molecules, it forms the ribosome.

The functions and distributions of these RNAs also vary.

For example, messenger RNA (mRNA), which is a translation template, exists in all organisms and is one of the basis for biological cell division and reproduction.

In addition to these three common types, there are also some special forms of RNA.

Such as XistRNA.

This is a type of nA, which exists only in the body of female mammals, and its function is to promote the transformation of an X chromosome in mammals into highly condensed Barrett bodies.

Reading at zero
XistRNA is a very interesting thing, we all know that when mammals develop, maternal mammals provide early embryonic cells.

But there are two X chromosomes in each early embryonic cell, but only one is left in the end, and it is this XistRNA that decides which one to keep.

...

In fact, it is reasonable to say that the two X chromosomes in early maternal embryonic cells should be the same, but there are no two identical chromosomes in biology.

Even from the same early embryonic cell, the two X chromosomes are slightly different.

Maybe a certain X chromosome carries a certain genetic disease gene, and when XistRNA acts on it, it can turn off one of them.

If the mechanism of XistRNA can be controlled, combined with genetic engineering, it is completely possible to avoid the occurrence of genetic diseases or chromosome-related diseases in early embryonic cells.

For example, Rett syndrome, a congenital disease, seriously affects the psychomotor development of children. It belongs to the category of neurodevelopmental disorders, and most of the onsets are women.

If the DNA fragment of Rett Syndrome is determined and it can be determined which RNA it is on, then using XistRNA can completely eliminate this genetic disease.

The ribonucleic acid found in cellular telomere modifiers is this special form of RNA.

In fact, strictly speaking, this special form of RNA is not simply RNA, but a ribonucleoprotein.

Because it not only has ribosomal RNA, but also a small amount of ribosomal protein, which together make up its structure.

However, the amount of ribosomal protein on it is very small, so small that it can be almost negligible, so it can also be called RNA.

Won is interested in the presence of RNA in the presence of cellular telomere modifiers.

This thing is one of the key substances to repair cell telomeres.

Just as XistRNA silences one of the X chromosomes in early embryonic cells, the ribonucleic acid present in cells' telomere modifiers can also work on cells' telomeres.

However, it works in a different way. It can act in the nucleus of the cell in a way that is still undetermined, and then synthesize a macromolecular riboprotein. This macromolecular riboprotein can act on the telomere of the cell to promote regrow.

This is the biggest achievement in Huaguo's research on cell telomere modifiers.

But it is a pity that every microorganism and small animal that was injected with ribonucleic acid did not burp within 48 hours.

That is to say, this ribonucleic acid is defective.

It can repair cell telomeres, but it can also cause cell death.

However, scientists in Huaguo speculated that there must be some kind of substance in the cell telomere modifying agent that can make up for this defect, otherwise this agent would be useless and useless at all.

The speculation is very reasonable, but it is a pity that until now, Huaguo has not been able to analyze from the medicine what kind of substance is playing a complementary role.

So even if it is confirmed that the cell telomere modifying agent ribonucleic acid can repair cell telomeres to a certain extent, Huaguo dare not apply its clinical trials to humans.

No one dared to start an experiment where 48% of the people would die within 100 hours after being injected with the test drug.

.

Hand rubbing nuclear fusion live in the wilderness

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