Doctor: start with the heart

Chapter 132 The direction and plan for the next step

The next day.

nine in the morning.

Research center meeting room.

Although it was an internal meeting of the research center, the dean and Wang Ming also attended it.

The theme of today's meeting is to have an open discussion on the development of the research center in the next step.

"Director, you can start now."

Tian Jinzhong, who was sitting next to Zhao Xu, said to Zhao Xu.

He has been in a very good mood recently. The funds that had been cut off have now been resumed, and the financial support for the research center is even greater than before. As the director of the research center, he has been very happy recently.

Moreover, he also heard a message from the ministry that when Zhao Xu's qualifications were sufficient, the dean, the nominal director, would retire to the second line. Zhao Xu became the director, and he would naturally become the deputy director.

This can be said to be his dream.

If he was still a cold bench in the ministry, I'm afraid he would never have such an opportunity in his life.

"Ah."

Zhao Xu nodded to Tian Jinzhong, then looked at the dean.

"Dean, would you like to say a few words first?"

When Tian Jinzhong saw Zhao Xu looking at the dean, he immediately knew what he meant, so he said to the dean respectfully.

"Okay, then I'll say a few words first."

The dean has been in charge of a hospital like the First Affiliated Hospital for so many years, so it can be said that he is very familiar with holding meetings.

Although Zhao Xu was very capable and talented, his experience in all aspects was still somewhat lacking.

So, from time to time, he and Wang Ming would come to support Zhao Xu.

"First of all, congratulations to everyone for overcoming the worldwide problem of advanced glioma."

The dean looked at the doctors present, especially at Zhao Xu, and said with satisfaction.

The research center was approved by the ministry and established under his hands. He is proud to have achieved such results in such a short period of time.

"Just last week, I went to the ministry to attend the national annual meeting of deans. The minister spoke highly of the research center. It can be said that the center has already gained popularity across the country. Of course, the center can have such The achievements made are inseparable from everyone's hard work. In the future, everyone will also work hard to make greater achievements. The support for the center will be further strengthened in the courtyard. Believe me, the treatment that everyone can enjoy in the future, It will get better and better."

After a pause, the dean encouraged everyone in the research center.

He didn't mean to make a big deal when he said this. Regarding the preferential treatment of the personnel of the research center, this was approved by the academy committee.

Moreover, other departments have nothing to say about improving the remuneration of the research center's personnel. Let's just say that these two recent cases, one is the recovery of high paraplegia, and the other is the cure of advanced glioblastoma. No department can achieve this kind of achievement. out.

What kind of achievements are there, what kind of treatment is given, this is what the dean has always insisted on, otherwise, the attached hospital would not have developed so big under his hands.

Hearing the dean's words, the team members of the research center were excited. Coming to the research center was the most correct choice in their lives!
"Thank you for your support from the academy. Next, let's discuss the future development and focus of the research center."

Zhao Xu looked at the dean, then at the crowd and said.

He also came from an intern doctor step by step, so he knew that for a doctor, treatment is still very important.

As far as he knows, many doctors are very hardworking.

Zhao Xu still remembered that when he was still an intern, a senior once told him that as a doctor, he is not afraid of hardship or tiredness, but he is afraid that his efforts are not worth it.

He has always kept these words in his heart, and it is still fresh in his memory when he thinks about it now.

"Everyone here knows that global regenerative therapy is a very cutting-edge medical field, and in regenerative therapy, stem cell therapy is the most promising regenerative medical field. Stem cells can generate all cells in the human body and have the potential to be used to repair tissues Injury and treatment of diseases. Furthermore, stem cells can self-replicate and differentiate into various tissues and organs. Mesenchymal stem cells also have immune regulation and anti-inflammatory properties. Therefore, the prospects for stem cell therapy are very broad. So far Say, I think we have to be trailblazers."

Zhao Xu said loudly.

"pioneer?"

Lu Chen asked with some doubts.

"Yes, it is a pioneer. For example, the two cases we have treated recently, one is high paraplegia caused by spinal cord injury, and the other is the treatment of glioblastoma. Both of them have one thing in common, that is All of them have carried out targeted cultivation of cell therapy. Therefore, our future work can focus on developing various directions of stem cell therapy, and provide other medical institutions with brand-new treatment ideas."

Zhao Xu said word by word, in an orderly manner.

This is the direction of the research center that he has been thinking about recently.

Stem cells can generate, cultivate and differentiate all cells in the human body, which determines that the application fields of stem cell therapy will be very extensive.

In the cutting-edge medical field, in fact, the way to make money is not by actually treating patients with medical expenses, but by developing new technologies and new treatment methods. Once a new patent or treatment method is developed, there will naturally be many medical biological companies to invest.

This is a very good way, and almost all high-end biomedical research centers do this.

Now, apart from the stem cell inducer developed by Zhao Xu, the research center has no other patents or treatment methods to follow.

"This idea is very good. The most important thing now is to innovate and make breakthroughs."

Hearing Zhao Xu's words, Wang Ming nodded and said.

His ability is extraordinary, but it is because he is in the emergency department that it actually limits his performance.

Therefore, he put a lot of hope in Zhao Xu.

Of course, Zhao Xu's current development and achievements have far exceeded his expectations.

"Yes, as long as the research center is always at the forefront, it will play a leading role, and there will be no shortage of policy support."

The dean also nodded.

His vision is more long-term. Now the country's support for high-tech is very strong.

The same is true in the medical field. In the past, whenever there were brand-new treatment methods or new drugs, they were basically developed by foreign pharmaceutical companies and hospitals.

Over the years, in this regard, it has suffered a lot from the import of drugs alone.

If you think about it, you will know that once the drugs developed by foreign pharmaceutical companies are exported, they will be sold at several times or even dozens of times the price.

Such a high price is a great burden for both hospitals and patients.

Now, in the overall technology strategy, the most important thing is to break this technology blockade.

Therefore, both the stem cell treatment center and Zhao Xu, who developed a stem cell inducer, have received high attention from the upper echelons.

"So is there any specific direction?"

Sun Chang thought for a while and said.

"The next step, I plan to focus on tissue and organ repair. Everyone knows that stem cells can differentiate into all normal cells, so all diseases caused by cell damage can actually be treated with stem cell cultivation. Stem cells have The potential of multi-directional differentiation, under specific conditions, through induction, it can differentiate and regenerate into neural stem cells, liver cells, islet cells and cardiomyocytes. Therefore, this characteristic provides a new idea for tissue engineering."

After a pause, Zhao Xu continued: "The next step, our work is to use stem cell therapy to break through uremia!"

As soon as Zhao Xu said this, everyone present felt shocked for a moment. This was a declaration of war against uremia!
Uremia is the terminal stage of all kidney diseases. Once uremia is diagnosed, there is no other way but life-long dialysis and kidney replacement. Due to the extremely high cost of treatment, uremia is also known as the most expensive chronic disease in the world. To the patient’s family and society, has brought a very heavy burden.

Moreover, as the incidence of kidney disease continues to increase, the number of patients with uremia has also been increasing. However, the treatment of uremia is single and expensive. It can be said that in all hospitals, except for patients with advanced cancer, the most hopeless Yes, it is a patient suffering from uremia.

Having uremia will not cause the patient to die immediately. During the developing stage of uremia, dialysis can still be used to maintain life. Slowly towards death.

The most painful thing is that in this process, not only the quality of life of the patient is very poor, but also a very heavy financial burden is brought to the family.

People and wealth are empty, which is the final outcome of most patients with uremia.

"Will this step be too big?"

While the dean was happy about Zhao Xu's ambition, he was also a little doubtful. A problem as big as uremia was definitely not something that could be easily solved.

"Dean, what I said is not aimless. I plan to use mesenchymal stem cells to slow down the damage of kidney cells, and gradually overcome uremia. We all know that diabetic nephropathy is the main complication of diabetes, and it is also The main cause of uremia. The main manifestation of diabetic nephropathy is the damage of kidney cells. Therefore, the injection of mesenchymal stem cells can be used to slow down or even repair cell damage.”

Zhao Xu said slowly.

Hearing Zhao Xu's words, everyone nodded. It was a good idea to start with one aspect, or the precursor symptoms of uremia, instead of conquering it as soon as it came up.

"In addition to using mesenchymal stem cells to slow down and repair kidney damage, we can also gradually adopt two methods for kidney transplantation for the treatment of uremia."

After a pause, Zhao Xu said again.

"Which two are they?"

Sun Chang asked.

It can be said that Zhao Xu's remarks were well-organized and well-founded, and he proceeded bit by bit from the place where he could start, which made people feel very feasible after hearing it.

"Let me talk about the first one first. We all know that at present, kidney transplantation is the ultimate method to treat uremia, but the biggest problem is that kidney transplant patients will experience rejection, which seriously reduces the quality of life of patients. Therefore, For kidney transplant patients, immunosuppressants are routinely used to prevent transplant rejection."

"It's a three-point drug, and immunosuppressants also have their limitations. Although they can effectively prevent rejection in a short period of time, long-term use will reduce the body's immunity and induce infection. This is the most important problem for kidney transplant patients. One of the causes of death is also a decisive factor in determining the survival time of kidney transplant patients. Therefore, I think that autologous mesenchymal stem cell infusion can be used to induce immune tolerance in patients, and improve kidney transplantation without immunosuppressants patients' prognosis and prolong their lifespan."

Zhao Xu spoke out the plan he had planned before in an orderly manner.

"This is very good. The cumulative number of kidney transplant patients in my country has exceeded 8. If mesenchymal stem cells can be used to induce immune tolerance in patients, then the quality of life of these kidney transplant patients will be greatly improved. It will also be extended."

The dean nodded affirmatively. Zhao Xu's thinking was very broad, and he did not limit his sight to a certain aspect, and his vision was more long-term.

"Then there is another one?"

Lu Chen asked curiously.

The others also looked at Zhao Xu curiously. After Zhao Xu said that he injected stem cells to repair damaged kidney cells and induce immune tolerance, everyone admired him very much.

There is another method, which means that the method left at the end is beyond the previous two methods.

This made everyone feel a little curious.

"If the first two treatments are indicators, then the last one is the root cause."

Zhao Xu said briefly.

"Cure the root cause? Are you talking about making an artificial kidney?"

Lu Chen's thinking was very quick, and she quickly thought of what Zhao Xu was going to say.

"Yes, we can use stem cell technology in living organisms to cultivate kidney tissue that can filter the host's blood and have normal functions. In this way, rejection can be avoided, and there is no need to wait for a kidney source. This is the root cause Methods."

Zhao Xu said slowly.

"Did you develop stem cell inducers because of this consideration?"

Sun Chang asked suddenly.

She had been curious before, why Zhao Xu wanted to develop a stem cell inducer, but now it seems that he has a series of plans.

"Well, in fact, normal human tissues and organs are cultivated through stem cell technology. This technology is also used by many hospitals and biomedical institutions, but the biggest problem is that the cycle is too long and the success rate is too low. Stem cell inducers can solve it The cultivation cycle is too long and the success rate is too low."

Zhao Xu explained.

Call ~
After Zhao Xu finished speaking, everyone present was shocked by Zhao Xu.

It turned out that he had a series of plans. In his mind, he had already drawn a blueprint, and he was waiting to realize it step by step.

What grand plans and dreams does this man have in his heart?

Lu Chen and Sun Chang both looked at Zhao Xu and thought at the same time.

(End of this chapter)