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Chapter 192 This will be a news that affects the world (please subscribe)

The news of the Naya Group spread across the country in an instant, causing heated discussions.

At this moment, everyone talked about this move of the Naya Group.

"I'm going? Is it true or not, Naya Group has launched a new type of SHR? No, it can no longer be called SHR, it should be called a new type of essential hypertensive mouse!"

"Haha, is it true or not? It would be great if it was true, so you don't have to be angry, those capitalists of the dog, let you be embarrassed." Even the well-educated scientists in the past happily swear.

"Support Naya, support domestic production!"

Whether it's true or not, Naya's announcement really boosted everyone's morale!
………………

But when everyone was discussing it, Macalite, an expert from the European Gene Bank, was sitting in the office.Holding a cup of coffee in his hand, he said with a smile: "Ponte, don't worry, if the new SHR is really that easy, the group of Chinese people won't book so many."

Poente looked at the computer silently, not knowing what he was thinking, he always felt that things were a little strange.

Tang Han understands that Naya Group and Longka are rivals for not a day or two. If the person who knows you best is not necessarily your friend, it is likely to be your opponent. Poente agrees with this sentence .

He feels that Tang Han is not the kind of bluffing person at all. That man is very courageous. If he doesn't do it, he must go all out to do it.

This announcement was officially launched by Naya, so it must have been authorized by Tang Han.

If this is the case, this matter needs further research.

Thinking of this, he called the person in charge of the Asian region: "You pay close attention to Naya's development, please let me know if you have any news."

Macalite sniffed the fragrant coffee, and scoffed at Pointe's cautiousness.

If the new model of essential hypertension is so simple, it will not be that they have been working hard for so many years and are still making slow progress.

"Poynter, I think what you should do now is not to be cautious about Naya, but to defeat this lie! I think this is just a delaying tactic by the Naya Group."

Point smiled: "I naturally believe in Mr. Wright's ability. In the field of genetic engineering, you may be the most professional. I will release new news now. One month later, the sales volume of SHR in Asia will be limited."

………………

After Zhang Hanlin saw Naya's announcement, he quickly dialed Tang Han's phone number, and now the two communicate frequently.

"Mr. Tang, has your company really developed a new type of mouse with essential hypertension?" Zhang Hanlin was still a little unsure.

Tang Han smiled: "Well, if there is no big problem, it may be true!"

Hearing Tang Han's confirmation, Zhang Hanlin also seemed to be encouraged in his heart!
"Beautiful! Give our countrymen a sigh of relief!"

Tang Han suddenly asked: "Aren't you surprised who did this?"

Zhang Hanlin was taken aback for a moment: "Who is doing something different? The Naya Group is full of talents, I believe there are always geniuses!"

Tang Han laughed: "Bai Ye did the research."

After hearing this, Zhang Hanlin let out a faint oh, and asked, "Did Bai Ye go to your place?"

Tang Han was a little confused: "Aren't you surprised?"

Zhang Hanlin: "Surprised? If someone else did it, maybe I should be surprised, but... Bai Ye, I should have gotten used to it, otherwise I would have a heart attack. Now you are telling me that Bai Ye was nominated for the Nobel Prize, I There will be no fluctuations in my heart. How do you say that? Steady as a dog!"

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Just as everyone was paying attention to the news of the essential hypertensive mice, Bai Ye finally finished writing his thesis on the unstable gene of KM mice.

The name is: "Apologizing for those experiments in the past, the real culprit of death in clinical trials is actually - unstable guanine"

He restored and wrote all the experimental data, and for the sake of insurance, he also backed up several copies of the data.

The gene of this stable KM mouse does not change much after removing that guanine. During this time, Bai Ye tried to remove which guanine base in the embryonic cell nucleic acid.

But this kind of operation is no longer possible for him, because it is difficult for the base contained in the mouse embryo to undergo further changes when it does not react.

Just like a defense mechanism, this base will only play its role when a series of reactions occurs.

Bai Ye communicated the news to Dong Cunguang, but he also frowned, unable to do anything.

What should I do?
Experts in the field of genetic engineering don't know much about themselves, right!Zhang Shulan.

This is a celebrity who graduated from a world-class prestigious school, maybe she will have a way?

After Bai Ye called Zhang Shulan, he told her about his discovery. Zhang Shulan was silent for a while, and then suddenly said, "Come to the Institute of Bioengineering, Chinese Academy of Sciences. I'll wait for you in the office."

After Zhang Shulan hung up the phone, although her words were calm, her heart was like a volcano erupting under the sea!
The news that Bai Ye brought him was too shocking. KM mice are recognized by the world as being extremely stable and most suitable for human research and experiments.

But can it be proved that this view is wrong?

if true...

The consequences are unimaginable. This is not just a mouse problem. If it is proved that the instability of KM mice does exist, then many previous experiments failed...and so many marketed drugs have problems...all can be explained.

So after understanding this problem, Zhang Shulan asked Bai Ye to come to the office directly. Bai Ye was not in a hurry, but she was fidgeting agitatedly.

After Bai Ye arrived, the two closed the door directly. Bai Ye had already opened the notebook he had prepared, and all the data was recorded in it.

Zhang Shulan carefully looked at the data and the analysis results of the experiment, holding a piece of paper in her hand, and kept writing and drawing, hoping that Bai Ye had a problem in that link.

To be honest, she didn't want Bai Ye's conclusion to be true.

Because if this is true, it is very likely that the medical market will face a huge turbulence for a long time in the future. This is not a good thing, and people's emotional panic is also a disaster.

But after reading most of them, Zhang Shulan sighed, fortunately... This kind of genetic instability only happens in a few cases, and it is not easy to trigger.

Zhang Shulan looked at Bai Ye, a little curious: "How did you think of studying this?"

Bai Ye said: "This involves the research of a new drug in the past. Back then, I published a paper in "Cell" magazine..."

After Bai Ye told about Ke Ao, Zhang Shulan's eyes widened and she suddenly said:

"You mean the Mikasu-Trangli incident?"

Bai Ye was taken aback: "Mr. Zhang, do you know?"

Zhang Shulan sighed: "Mikasu is the one nominated for the Nobel Prize. If he didn't have that, it is very likely that he will be the next Nobel Prize winner. It's a pity, as the world's top professor in the field of microbiology Coffee, his research on microbes is definitely not comparable to others."

"I was still doing research at Johns Hopkins. I heard that Dr. Mikasu invented a drug that can inhibit the expansion of tumor cells through the study of a single microbial cell. There is a lot of uproar, if the drug is invented, it will definitely be a blessing for the tumor industry."

"At that time, the experiment attracted the attention of countless people. As a foreign star experiment at that time, the scientific research funding reached 12 billion U.S. dollars. All the experimental data, experimental equipment, and participants were top-level existences in various industries. The first phase After the animal experiments were successful, major institutions and pharmaceutical companies made sky-high promises one after another, and even prepared a reserve fund of nearly 20 billion for follow-up clinical trials."

"Even "Nature", "Science" and even Time magazine were ready to put Dr. Mikasu Tranley on the cover at that time, just waiting for the results of his clinical trials!"

"Unfortunately... in the first phase of the clinical trial, all the experimenters who participated in it died at an accelerated rate. Instead of curbing the growth of tumor cells, it inhibited the growth and development of normal human cells..."

Speaking of this, Zhang Shulan sighed: "In the following years, they have been searching for the reason, but unfortunately they did not find any reason, and Dr. Mikasu suffered from severe anxiety and depression under the pressure of public opinion and self-condemnation. committed suicide in the laboratory."

The room fell into silence, and Bai Ye finally understood the whole story. It turned out that this incident was so famous.

Zhang Shulan said with regret: "I also participated in the speech of Dr. Mikasu, who was really the most remarkable figure in the field of microbial engineering. His death is a great loss for the entire field of human bioengineering."

Speaking of this, Zhang Shulan suddenly looked at Bai Ye with a complicated expression: "It would be great if you could have been born a few years earlier, maybe... he doesn't have to die. He is only 59 years old, and he has achieved such a great achievement..."

In the next few days, Bai Ye and Zhang Shulan restored the experiment about the unstable gene from the beginning to the end, and still got this unstable base.

Zhang Shulan looked at Bai Ye and said, "Where are you going to post this article?"

Bai Ye shook his head: "I haven't figured it out yet, maybe it's MIO, because this is also an article in the field of experimental animals. But "cell" is also fine, after all, Ke Ao is the editor-in-chief there, let him publish this article, Perhaps it would be more appropriate, at least it would allow him to..."

Zhang Shulan was stunned for a moment and asked, "Why don't you post it to the Journal of the Chinese Academy of Sciences?"

Bai Ye: "Huh?"

Zhang Shulan blushed suddenly: "You are also a graduate student of an academician of our Chinese Academy of Sciences, what's wrong with publishing it in our academic journal..."

""Journal of the Chinese Academy of Sciences" is also at the SCI level, but the impact factor is relatively low. In fact, our level is good, mainly because of the poor international influence. If your article is published on it, maybe it can improve its international reputation. status……"

Bai Ye was taken aback, and asked awkwardly, "Is this okay?"

Zhang Shulan also smiled awkwardly: "Actually, it's the same everywhere. The point is to spread the news. That's the most important thing, isn't it?"

"Besides...you now have an impact factor of 258 points, which is better than many mentors, and you don't lack this article, right?"

..............................

Bai Ye called Ke Ao that day.

"Hello? Bai Ye, can you consider the time difference when you call next time? It's 3 o'clock in the morning." Ke Ao said helplessly.

How could Bai Ye still think about this question at this time: "Keo, if I tell you now that I found out the reason for your teacher's failure, would you think I disturbed your sleep?"

Suddenly, there was a moment of silence on the phone: "This joke is not funny..."

Bai Ye smiled: "What I said is true, I really calculated it, the failure of the whole experiment has nothing to do with your teacher."

Ke Ao was stunned: "Is what you said true?"

Bai Ye nodded: "Maybe you can come to the Chinese Academy of Sciences in Kyoto. I have a detailed experiment process here."

The next afternoon, Ke Ao arrived. As soon as we met, Ke Ao walked towards Bai Ye with red eyes: "Are you sure what you said on the phone is true?"

Bai Ye nodded: "Come with me, I'll take you to prove it yourself."

Bai Ye took Ke Ao and Zhang Shulan, and the three restored the experiment again. After seeing the results of the experiment, Ke Ao burst into tears.

A 1.8-meter tall man cried like a child, and Zhang Shulan couldn't bear it.

Three days later, the "Proceedings of the Chinese Academy of Sciences" published a special issue. The cover was not Bai Ye, but the KM mouse and Dr. Mikasu Tranley's head.

On the cover there is a title:
"Redressing those past experiments, the real culprit of death in clinical trials is actually - unstable guanine"

"Journal of the Chinese Academy of Sciences" still has some influence, especially in Asia, after all, the technical content is still very high.

Therefore, the special issue has just been published, which has aroused heated discussions among many people.

"Impossible? We have been using KM mice for so many years, but there is a problem?"

"Generally there will be no problem. Didn't you see the above? Only under special conditions will there be a slight mutation."

"But... this is also terrifying!"

"It turns out that Dr. Mikasu died because of a mouse!"

"Oh! My God, is this true? It's unbelievable."

For a time, in the entire scientific research field, many people who are concerned about bioengineering information saw the information in this weekly magazine and immediately started discussing it.

This news was so shocking that everyone had to doubt his reliability.

The KM mouse that people have used for so many years turned out to be an unstable mouse, and it may even change differently from the human body, which is terrible.

Moreover, not only these bystanders, but many cases of scientific research failures began to reflect on whether they used KM mice at the beginning, and how much influence the mice had on their experiments.

(End of this chapter)