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Chapter 346 A Cross-Era Nail

【Ding!Obtained absorbable bone nails, product properties: the initial bending strength of the material is 375Mpa, the shear strength is 320Mpa, the strength maintenance time is 12-18 weeks, and it can be completely absorbed by the body within 3 years.Compared with traditional materials, the degradation speed and bone healing speed are matched, and the conductivity is excellent, which is conducive to bone healing. 】

【Ding!Congratulations, you have obtained an absorbable bone screw. Tip: This is an absorbable bone screw produced by BUIS. This bone screw is the fourth generation bone screw. The material is a new type of synthetic biodegradable material. There are many advantages. 】

【Reminder, the material is a high molecular polymer material, poly-KL-lactic acid is the main raw material, which can be decomposed into carbon dioxide and water in the human body, which is harmless to the human body. Compared with traditional bone nails, it combines the traditional titanium metal Advantages and the absorbable advantages of polymerized lactic acid products...the advantages are obvious, researching this item requires: material science lv6, orthopedic technology ability lv6, biomedicine lv5. 】

The moment Bai Ye saw the nail, he naturally understood what it was!

After all, my own system is different from others, it is a good system for the conscience to serve the host, eh!

The things that came out naturally couldn't be waste.

At present, the main material of absorbable bone nails is PLA material. As an orthopedic internal fixation material, PLA material has even revolutionized traditional materials. It can be said that it is the most advanced orthopedic internal fixation material in the world.

As we all know, traditional internal fixation materials for fractures are generally made of stainless steel, titanium and their alloys, but long-term implantation will cause corrosion, allergies, osteoporosis due to stress shielding, and fractures after surgery, and most of them require two times out.

In recent years, many fracture fixators made of absorbable materials have been used clinically and have achieved good internal fixation effects.

Compared with metal internal fixation, its most clinically attractive advantage is that in cases of fracture internal fixation with polymer biodegradable material devices, there is no need for another removal operation after the fracture has healed.

Absorbable boards and nails are generally made of absorbable biodegradable material polylactic acid.Polylactic acid is non-toxic to the human body, has good biocompatibility, and does not cause inflammatory reactions and foreign body rejection reactions in surrounding tissues.Its degradation products are glycolic acid and lactic acid, which can participate in the carbohydrate metabolism cycle in the body, undergo a series of biochemical reactions, and finally degrade into carbon dioxide and water to be excreted from the body.

No residue, no stimulation to tissues, no toxic side effects.In addition, polylactic acid has good mechanical strength and elastic modulus. By adjusting the molecular weight, choosing different polymerization methods and molding methods, the mechanical properties and degradation speed of polylactic acid can be adjusted and controlled to meet different clinical needs.

Moreover, what surprised Bai Ye the most were several properties of this new material, such as the initial bending strength and shear strength of the material.

Because the main functions of bone nails and fixation plates are the broken ends of bone nails, these fixing materials are required to withstand strong strength and tensile strength.

Although this PLA material is absorbable, its strength is very insufficient, which is a very important drawback.

In the past, it was precisely because of the weak mechanical properties of this kind of absorbable biodegradable internal fixation that it limited its wide application.

In clinical practice, polymer biodegradable materials must have physical properties such as considerable hardness, sufficient stability, and complete degradation in the human body, without any complications.

Over the years, foreign researchers have continuously innovated and tackled key problems, and the polymer biodegradable implant device has met the above requirements and reached the predetermined goal.

However, even so, the initial bending strength of the material is only 175Mpa, and the shear strength is 120Mpa, but the strength of the nail in my hand has more than doubled!

This more than twice the capacity is enough to match most of the current alloy materials.

As for the degradation rate, in fact, the faster the better, the degradation rate of 12-18 weeks and the absorption period of three years are perfectly in line with the fracture recovery of human beings.

When the fractured bone segment is fully healed, it begins to disintegrate and absorb in the body.

This degradation speed not only ensures the good in-situ healing of the bone segment, but also avoids the stress shielding effect in the later stage of bone healing, which is beneficial to the reconstruction of the later stage of bone healing.

It can not only promote the healing and reconstruction of bone, but also decompose and excrete from the body after healing, avoiding the possible adverse reactions of implants stored in the body for a long time.

At present, the raw material used in absorbable bone fixation products is mainly PLA (polylactic acid). PLA has been widely used in clinical treatment because it has been certified by the US FDA.

Although it is a little embarrassing, I have to admit that all the materials used in our country, such as bone needles, bone nails, orthopedic fixation plates, are imported!

That's right, all of them!

Because there is a big lag in the development of our domestic PLA synthesis technology, the synthesis technology has not been broken through, especially the lack of preparation technology for high-purity chiral monomers, resulting in the PLA-type orthopedic products being unable to be industrialized.

Of course, it does not mean that the PLA material is perfect, it can only be said that compared with the previous materials, it has a lot of progress.

At present, the shortcomings of PLA materials as orthopedic internal fixation materials have the following aspects:
1: It does not have osteoconductivity, and the speed of repairing bone defects is very slow. For large bone defects, it is difficult to achieve complete bone repair.

2: The mechanical strength of the material is not enough to be used as an internal fixation material for fractures in bearing parts:.

3: Its early biodegradation speed is so fast that it cannot guarantee to meet the mechanical performance requirements before the new bone tissue grows out, and the mid-term degradation speed is too slow, so that there are still residues left after the new bone tissue grows out. Complications in the body.

Therefore, the nail that Bai Ye obtained is completely an evolution of modern orthopedic internal fixation materials!

Moreover, although the PLA material is leading, there is still a potential risk factor. Bai Ye remembers that when reading the paper, many leading experts in Japan discovered that the PLA material is actually carcinogenic, and its experimental incidence rate is as high as 44%. However, some scholars have questioned its experimental design, so this issue needs long-term observation.

However, this just shows his shortcomings!

So, when Bai Ye saw this nail, his heart jumped for no reason.

This is not only a nail, but also not just a product, this is a new era!
Bai Ye feels that if this kind of absorbable bone nail can be developed and the material can be researched, it can be used as an orthopedic internal fixation material.

Moreover, if this material is used well, it can be used in too many aspects and fields.

Once this is done, it will be a future, an unlimited future!

Thinking of this, Bai Ye was a little excited.

After all, we can research and produce world-leading orthopedic materials ourselves.

Bai Ye is confident that what he can do is to usher in a new era.

Carefully putting away the bone nail, Bai Ye's imagination wandered.

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To be honest, Bai Ye found a problem, that is, more and more, with the improvement of his subject skills, he found that the surrounding supporting facilities were more and more unable to keep up.

He even feels that medical materials, medical equipment, medical medicine, etc. are all very important and critical things if he wants to further improve the level of subject skills.

Think about it, a very intuitive question.

For example, what is the difference between an orthopedic doctor 30 years ago and an orthopedic doctor of the same level today?
The difference is a lot, because with the development of science and technology, ideas and so on are constantly updated.

In the past, there were not many CTs and MRIs in China, but now with the help of these auxiliary tools, many intractable diseases have been discovered and treated.

This is progress!
Therefore, medicine, whether it is traditional Chinese medicine or Western medicine, is actually a discipline that cures diseases and saves lives.

Their ultimate purpose will be to serve humanity.

Thinking of this, Bai Ye smiled gratefully at the virtual screen.

Without him, maybe I'm just an ordinary person!
When he returned to China, the first thing Bai Ye had to do was to improve the talent allocation of the scientific research institute.

Do not!
I have to start researching now, maybe I can hold a job fair in Los Angeles tomorrow!

Thinking of this, Bai Ye felt that this matter was very feasible.

After all, I just cured your Los Angeles hero. In Lao Bai's words, I am now a popular figure, a figure standing at the forefront of public opinion.

Moreover, Los Angeles is also a good place!

The location of Caltech University, as a world-renowned private research university, although small in scale, has a long-standing reputation in the world of science and technology.

Its dominant disciplines are in physics and chemistry, astronomy and space science, and it is also an international leader in materials science.

Although the scale of this school is small, and the total number of students in the school is only more than 2000, but in history, this school has gone out to 36 Nobel Prize winners!
What a terrifying number!

Moreover, it is the university with the highest density of Nobel Prize winners in the world.

So if Bai Ye returns empty-handed, he will not forgive himself.

Thinking of this, Bai Ye felt that it was necessary to have a chat with Mr. Wynn about this matter tomorrow.

Maybe tomorrow I can bring back a top-level talented material science student, but now I am very hungry for talents.

The Institute of Orthopedics Bai Ye does not plan to treat it as an ordinary hospital, he wants to treat it as a world authoritative base of orthopedics.

This is not just for research and treatment, but for any products in the field of orthopedics, I have the final say!
This is authority!
In terms of academics, medical level, medical drugs, medical equipment, medical talents and other fields, all of them are at the highest level in the world!
As a distinguished life member, Bai Ye felt that his courage should be amplified.

Ps: The veteran feels that he can grow a little longer...I decided to write more big chapters in the future, so that it will be more comfortable to read. How do you feel?

(End of this chapter)