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Chapter 548 Found You!Chase the culprit thing!

[Deep Scan] is a very buggy support.

In the past year, Bai Ye has never been willing to use it, but today, Bai Ye decided to take it out.

Select [Zoom in], and the bacteria on the glass slide in front of him began to be magnified crazily. The bacteria No. NBOD-31, which could not be seen clearly even under an electron microscope, seemed very large at this time. Immediately, Bai Ye seemed to be in a huge of strange biospheres.

These wriggling flora in front of us are the mainstream organisms in this world. They are constantly moving and moving crazily in the petri dish.

Bai Ye first observed the cell wall of the NBOD colony, which is a magical cell wall composed of glycogen, which can even block the high temperature of more than 80 degrees Celsius, keeping him safe and sound.

It's his way of living.

After Bai Ye made the comparison, he found that there was no difference in the cell walls.

Afterwards, Bai Ye transparentized the entire cell wall.

The cell membrane began to appear, and the cell membrane was no different, as beautiful as ever, or like a hive, engraved with a large number of carrier proteins, allowing those cells to selectively secrete some substances to the outside of the bacteria.

As time passed by, Bai Ye suddenly felt that all this looked very charming.

Of course, the premise is that you don't have intensive phobia.

Cell membrane, continue to be transparent!

Every step, Bai Ye carefully took screenshots. He was reluctant to let this one [deep scan] go to waste. If there is nothing to gain, he can stay to study this bacterium.

Plasmid research, there are more than 130 genes in the plasmid that can transcribe bacterial genetic factors in the cell.

There was nothing to hide in front of Bai Ye.

Plasmid comparison... Consistent!
Plasmid gene sequence... Consistent!
Quasi-nucleus comparison... Consistent!
The comparison of the genetic genes in the quasi-nucleus...consistent!
What is the problem?
Is there any difference between them before and after?

At this moment, Bai Ye used [a brainstorm]!
At the moment when the idea came into being, the countless pictures that just appeared in Bai Ye's mind began to be reorganized. These large numbers of pictures and photos were even quickly connected, looking for a breakthrough!

The brain of Bai Ye who is so busy is like a super computer!

Immediately, Bai Ye's eyes lit up. He found the difference. Although it was very subtle, he finally found it!
Unexpectedly, really unexpected, there is a very hidden ribosome on the cell membrane of this bacterial group!
Unexpectedly, this bacterium has two ribosomes!
This was beyond Bai Ye's imagination.

There is only one ribosome in the normal NBOD-31 bacterial population, but the mutated bacterial population actually has a special characteristic hidden under the cell membrane, even hidden in the "hive" substance on the cell membrane. Ribosome!

This is where the variation comes in!

What is the difference?

Bai Ye had a vague feeling that this should be where the mutation lies, and this should have a lot to do with the occurrence of bowel cancer.

What the hell is it!
The structure of the ribosome is significantly different from other organelles. It has no membrane coating and consists of two subunits. Because of functional requirements, it can be attached to the endoplasmic reticulum or free in the cytoplasm. The ribosome is sometimes not considered a type of organelle, but are intracellular macromolecules.

So at the beginning, Bai Ye easily thought it was a substance on the cell membrane.

Ribosomes are responsible for completing the process from RNA to protein in the "central dogma" in the cell, which is called "translation" in biology.

Before translation, the small ribosomal subunit will first combine with the messenger RNA transcribed from the nucleus, and then combine with the large ribosomal subunit to form a complete ribosome, which can use the transfer RNA in the cytoplasmic matrix to transport amino acid molecules Synthetic peptides.

After the ribosome has finished translating a single strand of mRNA, the large and small subunits separate again.

Therefore, its only function is to synthesize amino acids into protein polypeptide chains according to the instructions of mRNA, so ribosomes are molecular machines for protein synthesis in cells.

Anyone who has attended high school biology knows that this is the so-called protein processing factory.

Because there are no mitochondria in bacteria, there is only such a ribosome as a secondary processing plant.

With transparent ribosomes, Bai Ye finally saw the mutation.

At this time, Bai Ye happened to see this "false ribosome" processing factory forming a polypeptide chain, forming a protein... This is a new substance.

What is this substance?
What is the effect?
This has faintly become a major factor and breakthrough point to break through bowel cancer.

However, this substance was not secreted, but attached to the cell wall, as if adding a new weapon to the cell wall, which seemed to be defensive and offensive.

Although it looks the same as the original NBOD-31, it is almost the same, but if you study carefully, you can still find the difference.

The main difference is the chemical structure!

The functions of the bacterial cell wall include: maintaining cell shape, improving mechanical strength; inhibiting mechanical and osmotic damage (the cell wall of Gram-positive bacteria can withstand a pressure of 20kg/cm2), mediating intercellular interactions (invading the host); preventing large Molecular invasion; assists cell motility and growth, division and flagellar motility.

The cell wall thickness varies with different bacteria, generally 15-30nm.

The main component is peptidoglycan, a disaccharide unit composed of N-acetylglucosamine and N-acetylmuramic acid, connected by -1 glycosidic bonds to form a macromolecule. N-acetylmuramic acid molecules have tetrapeptide side chains, and short peptides between adjacent glycan fibers are bridged by peptide bridges (Gram-positive bacteria) or peptide bonds (Gram-negative bacteria) to form peptides The polysaccharide sheets, like plywood, are bonded in multiple layers.

A combination of such layers can make the cell wall more functional.

And this new substance forms a new layer on the surface of the cell wall. This layer is very unusual!
Although it is only this layer, but because of this simple layer, major mutations have occurred in this flora.

Turned into two different substances!

[Deep scan - end! 】

Bai Ye closed his eyes, this time, he gained a lot!

The next time is to extract these cell walls, and then experiment in animals to study whether there is a gap.

The separated cell walls are ready-made, and Bai Ye directly arranges the experimental group to carry out the experiment. This time, Bai Ye is not acting alone.

Unexpectedly, a week later, a report came from the experimental group!
This cell wall can act directly on intestinal epithelial cells to form cancer cells.

Bai Ye's eyes lit up immediately!
The answer has been found!
I finally found you, the culprit who has been confused for a long time, it turns out that you are hiding here.

(End of this chapter)