I really don't want to be a doctor

Chapter 341 Hong Sheng's Change

"Hi, Teacher Zhu."

Wearing a white coat, Hong Sheng stepped forward and said with a bow.

"Well, not bad." Zhu Xianqing smiled slightly, "I just heard that you have solved a problem that has plagued the myocardial mesenchymal stem cell project team for a long time?"

Hong Sheng chuckled, touched the back of his head embarrassingly, and said, "It's just luck."

"Don't be so modest, scientific research often requires such luck." Zhu Xianqing said.

Although divided into two different project groups, Zhu Xianqing also has some understanding of "cardiac mesenchymal stem cells", and the two projects often discuss and consult with each other.

He is well aware of the current problem of "myocardial mesenchymal stem cells", but the relationship between long-term colonization of myocardial mesenchymal stem cells at the injury site and its therapeutic effect on diseases has not yet been clarified.

The mechanism of this pathophysiology is extremely complex and requires rich knowledge and practice. With Hong Sheng's current ability, how could he come up with a solution?

Hong Sheng is currently positioned as an "experimental dog". Although his experimental operations are more proficient than when he first arrived in the laboratory, he can only be regarded as an "experimental old dog" at best.

"Hong Sheng, tell me your thoughts on this experimental project." Zhu Xianqing said.

Shenzhou Laboratory, in a conference room dedicated to holding experimental group meetings.

Zhu Xianqing presided over it personally and called all the personnel in the laboratory to discuss Hong Sheng's experiment.

It has been more than half a year since the establishment of Shenzhou Laboratory. From the beginning of a "small workshop" with less than ten employees, it has gradually become a "big factory" with nearly 40 employees and has begun to take shape.

In addition, according to the cooperation between Jing Xiaoran and Ning'an Hospital, the first batch of Ning'an Medical College students have come to Shenzhou Laboratory as free labor.

Hong Sheng stood on the stage with a nervous expression. He didn't know whether to put his hands in his pockets or behind his back.

All the experimenters present here basically have a master's degree or above, and his "experimental dog" who has not yet graduated from a bachelor's degree is really a rare animal.

In short, he felt that everyone's eyes were on him, and he felt a little uncomfortable.

He suddenly missed the time when he followed Jing Xiaoran. At that time, other people's eyes were on Jing Xiaoran, no one would notice him, and he would not feel any pressure.

Fortunately, everyone's eyes, including those young and beautiful experimenters, looked at him "affectionately".

After this speech, maybe try to confess?

Old Hong Sheng blushed, and suddenly stammered: "Zhu, Mr. Zhu, it's actually nothing. It's your immune checkpoint inhibitor project that gave me some inspiration."

"Immune checkpoint inhibitor project? Gave you inspiration?" Zhu Xianqing became interested, and immediately excitedly said: "Tell me your thoughts."

The way Zhu Xianqing looked at Hong Sheng was like seeing a coolly dressed beauty, his eyes were shining.

Hong Sheng swallowed, took a few steps back, and said, "It's like this, Mr. Jeffrey has been thinking about the relationship between the long-term colonization of MSCs (cardiac mesenchymal stem cells) at the injury site and its therapeutic effect on the disease. There has never been a particularly good way to prove the relationship.”

"I know that." Zhu Xianqing nodded, "The mechanism of action of MSCs in vivo and in vitro is different."

Hong Sheng said: "Well, all I want is the relationship between MSCs and immunity. I did a preliminary experiment and found that the therapeutic effect of MSCs is mainly through the secretion and expression of a series of immunosuppressive factors, cytokines, growth factors, etc. to regulate inflammation and tissue stability. These factors mainly include interleukin-6, transforming growth factor-β, prostaglandin E2, etc.

Zhu Xianqing frowned slightly. These should be very simple experiments, and generally those involved in the field of MSCs should know, "But these can't prove the relationship between MSCs and immunity, right?"

Hong Sheng talked about the field he was familiar with, and he spoke fluently, and then continued: "So I used marker molecules such as nestin, leptin receptor, Gli1, and fibroblast activation protein to track and study specific MSCs in vivo. We found that MSCs and their subsets can broadly inhibit the activation and function of a variety of immune cells, including macrophages, granulocytes, natural killer cells, dendritic cells, T cells and B cells.”

What Hong Sheng said was already very professional, and many people off the court could no longer understand it.

Especially the group of "free labor" from Ning'an Medical College, everyone's eyes were full of doubts, and they didn't understand what the two people on the stage were talking about.

Perhaps picking out each word individually, knowing its meaning, and combining them together is completely a "scripture from heaven".

"MSCs can not only inhibit the proliferation of T lymphocytes, but also inhibit the differentiation of initial T cells into Th1 and Th2 cell subsets, and promote the production of regulatory T cells. Inhibiting the immune response can promote the healing of wounds at customized sites!"

"What about your specific experimental steps? What is the difference between the mouse in vivo model and the in vitro model?"

"For example, the adjacent endosteal nestin+ cells have the characteristics and functions of MSCs, which can form new colonies in the bone marrow, have three-way differentiation potential, and participate in the maintenance of hematopoietic stem cell niche function..."

On stage, Hong Sheng answered every question Zhu Xianqing asked fluently.

In the audience, everyone watched the performance of these two people.

Among the "audience" under the stage, there is a special existence, she is Luo Xin, a classmate of Jing Xiaoran and Hong Sheng, and the deputy monitor of the second class.

In her junior year, she did not choose to come to Fancheng Central Hospital for an internship. Instead, she stayed in the headquarters of Ning'an Medical College and continued to study in the laboratory of Ning'an Medical College.

This time, she got the opportunity to study in the Shenzhou laboratory through untold hardships.

Looking at Hong Sheng, who was in high spirits on the stage, chatting with big names in the medical circle like Zhu Xianqing, Luo Xin felt dazed for a while.

As the deputy monitor of the class, she knows every student in the class very well.

Hong Sheng, isn't he the guy who secretly swipes his phone at work, blushes when he meets girls, and walks behind Jing Xiaoran every time?
However, where he is standing now, what he is talking about, and the people he gets along with are all completely out of her reach!
Luo Xin looked at the admiration in the eyes of the students around her, and felt extremely unwilling.

She stayed up late every day to do various experiments in the laboratory of Ning'an Medical College, but in the end she could only fight for a place in the Shenzhou laboratory.

And her old classmate, whom she once looked down upon at all, has already stood in a position out of her reach.

Are these Hong Sheng's own efforts?

Luo Xin didn't believe it, a figure appeared in her mind.

Perhaps, it is because of him that Hong Sheng has achieved what he is today.

(End of this chapter)