The Tang Dynasty started from saving Empress Changsun

Chapter 256 Smallpox Vaccine
Chen Jingke continued to explain the reasoning in his own words: "The elders in my family guessed that genes secrete a special substance."

"When a person eats another person, his genes sense the substance and know he's eating his own kind."

"Then produce prions to kill him, so as to prevent him from eating other people of the same kind, and ensure that human beings can pass on."

Fearing that Sun Simiao would continue to question, he simply said: "Actually, these are inferred by the elders based on the reality, and the genes are also hypotheticals derived from the inverse. I don't know if it is true."

"The reason why this hypothesis is recognized by the elders is because of reasoning based on this hypothesis, it is found that many phenomena can make sense."

Sun Simiao agreed: "Using your words, our methods of observing the world are still too backward, and many things can only be hypothesized based on appearances... Do you want to make bold assumptions and be careful to verify them?"

"Genes and cannibalism produce prions. It is indeed a very interesting hypothesis, not to mention that experiments have been done with cattle...Any other speculations?"

In fact, Chen Jingke didn't know that there were major mistakes in his understanding of prions.

However, he himself didn't know this. Seeing that Sun Simiao accepted this hypothesis, he was relieved and said, "Yes, they also discovered many interesting things during the research, which can be explained by genes."

"When a person only eats [-]% of their meals, and when the seasons change, don't change clothes immediately, but cover them in spring and freeze in autumn... This person's body will be particularly strong and not easy to get sick."

"When a person eats full every meal and changes clothes early when the seasons change...the person's physical condition is average instead."

"Extend this observation timeline to 20 years, 50 years, or even longer."

"It was found that the physical fitness of the latter and their descendants is getting worse from generation to generation, and it is becoming more and more difficult to give birth to healthy offspring, and in the end it will even become difficult for offspring."

"The elders speculate that this is the function of genes. When a person's living conditions are relatively poor, genes will explode with more potential in order to pass on..."

"When a group of people live in a very favorable environment for hundreds of years and generations, the genes will become 'lazy'..."

"Of course, reasonable living and eating habits and proper exercise are the most important factors. Hungry every day, hungry and full, and exhausting your physical strength to exercise is courting death."

"If this conjecture is true, the health preservation plan we have formulated will get twice the result with half the effort. For example, eating only [-]% of the full meal, such as spring covering and autumn freezing... all have a certain reason."

Sun Simiao was noncommittal, but said: "Is there any more? Let's continue."

Chen Jingke took a breath and said, "One of them is related to asthma."

"The family once built a large number of workshops on an island, which produced too much smoke and caused poor air quality."

"People who breathe this polluted air for a long time will get various diseases, especially various respiratory diseases."

"When the elders learned of this situation, they moved some of the workshops to places far away from human habitation. The air quality has improved, and everyone is very happy."

"But no one expected that in the next few years, the chances of people living on the islands to be infected with asthma increased several times."

"They searched for all kinds of suspicious points, but found no problems. In the end, they could only make assumptions from the genetic aspect."

"Genes perceive that local people live in polluted air and are prone to respiratory diseases, so they strengthen their resistance to respiratory diseases."

"When the air quality becomes better and the gene detects that the danger is relieved, it stops strengthening this aspect, which instead leads to a concentrated outbreak of asthma."

Sun Simiao nodded slowly, and said, "This is an interesting guess, but it's not enough to prove that genes are at work."

Chen Jingke did not refute, but mentioned another example: "There is also smallpox. As we all know, people who have been infected with smallpox will not be infected a second time."

"In fact, cows can also be infected with smallpox, that is, cowpox. Then the elders discovered that some milking servants were infected with cowpox, and after recovering, they would not be infected with smallpox."

"After research, they were surprised to find that the toxicity of cow smallpox is very low. People infected with cowpox will not only develop large areas of pox, let alone kill people."

"So they took the initiative to vaccinate against smallpox, and then discovered that after successful vaccination, they could actually be immune to smallpox."

"Wow." Sun Simiao stood up from the chair suddenly, stared at him closely and said, "What you said is true?"

Chen Jingke knew why he was so excited, and said affirmatively: "Of course it is true. Many people in the family have been inoculated with cowpox, and then they will not be infected if they take the initiative to contact smallpox patients."

Sun Simiao was trembling with excitement, and said, "Have you been inoculated with cowpox?"

Chen Jingke shook his head and said, "No, but I have been vaccinated against tuberculosis, and I am resistant to tuberculosis until I am 24 years old."

As he spoke, he rolled up his sleeves, revealing the scar on his left arm, and said, "This is the scar left by the tuberculosis vaccination."

In fact, it is the BCG vaccine. In 1980, the United Nations announced the eradication of smallpox. Since then, it has not been vaccinated against smallpox.

In China, the smallpox vaccine was changed to the BCG vaccine to prevent tuberculosis.

It's just that the BCG vaccine is not effective for life. It is close to 100% immune under the age of four, and has a probability of immunity of more than 15% between the ages of four and 90.00.

十五到24岁免疫概率60.00%五左右，25到35只剩20.00%，年龄再大就没用了。

Sun Simiao became even more excited, and said, "Can you also be immune to tuberculosis? How do you do it?"

Chen Jingke shook his head and said: "The tuberculosis vaccine is very complicated. It seems that tuberculosis bacteria are extracted from cattle for cultivation."

"It takes more than ten years to make the bovine tuberculosis virus lose its toxicity, and then inoculate people. Only an elder understands the method of cultivation, and no one knows about it after his death."

Sun Simiao's face was full of disappointment, and he was in a trance. He said, "Is that so? That...that's a pity."

Chen Jingke was afraid that he would not be able to bear the blow, so he said quickly: "However, cowpox is relatively simple. Just make a small cut on your arm and apply the cowpox liquid on the wound."

"Under normal circumstances, it can fully return to normal in about half a month, and the body will develop resistance to the smallpox virus, and will be immune to smallpox for life."

Sun Simiao's anti-strike ability is very strong. Although it is a pity that he missed a new medical skill, it is also a great surprise to get the method of cowpox.

However, he still said cautiously: "Are you sure the method of cowpox is feasible?"

Chen Jingke said with certainty: "It's feasible. I have seen many people who have been vaccinated with vaccinia. I wanted to get vaccinated too, but unfortunately, there was a major change in my family and I didn't get it."

"Later, I was sent to Datang, where I met you, Master."

Although Sun Simiao was willing to believe his disciples' words, he still said out of caution: "The matter is very important. I have to test it myself before I can confirm whether it is true or not."

(End of this chapter)