i have a wasteland world

92 Octopus
Hu Mingming doesn't drink, so he doesn't know the news about the liquor industry.

I don't know about Chen Xiao's achievements.
It can be seen from this point that his entrepreneurial failure is inevitable.

Hu Mingming: "Mr. Chen, if you have anything to do, just ask. If you can help, you will never refuse."

Chen Xiao talked about his Yangshengtang business, his cooperation with Liu Qiming, a master of traditional Chinese medicine, and the cooperation with several hospitals to carry out experimental treatments.
"...By cooperating with Mr. Liu, we found a drug that has a good effect on depression. How can we quickly market it?"

Hu Mingming was very surprised when he heard this.

Looking at Chen Xiao's age, he is no more than 30 years old,
Starting from scratch, he has successfully started many businesses.

Now it is crazy to extend its tentacles into the pharmaceutical industry.

As for the new drug he said, it has a good effect on depression...

Just listen to it.

Before which new drug is launched, it is not a hype.

The final product depends on the curative effect.

"If you want to go public quickly, you can take the road of accelerating the listing application."

Chen Xiao asked, "What are your requirements?"

Hu Mingming: "Generally speaking, there are four types, the breakthrough therapy drug procedure, the conditional approval procedure, the priority review and approval procedure, and the special review and approval procedure. Mr. Chen can take a look, which category does it fit?"

Chen Xiao thought to himself that there was a reason why the business surnamed Hu was unsuccessful.

Emotional intelligence is too low, and from the tone of voice, he obviously looks down on Chen Xiao's "antidepressant that works very well".

"It's all difficult, isn't it?"

Hu Mingming nodded: "Generally, it is suitable for breakthrough, emergency, rare, and sudden situations."

Chen Xiao asked: "Is there anything else?"

Hu Mingming curled his lips: "Pharmacy is a long-term project, and there are no shortcuts."

Chen Xiao: "That is to say, there is no way?"

The development and marketing of new drugs can be roughly divided into six steps:

1. Discovery of new drugs (find targets, synthesize compounds),
2. Preclinical research (toxicology research, formulation development, etc.),
3. Clinical research (Phase [-], [-], and [-] clinical trials),

4. New drug application,

5. Approval for listing,

6. Post-market surveillance (Phase IV clinical research),
For Chen Xiao, there are several hurdles to overcome when serotonin types I and II want to be marketed.
Although steps 1, 2, and 3 are not used, there must be experimental data.

Otherwise, if the material application is submitted out of thin air, they will not accept it at all.

Chen Xiao knows to go through the process again. Although it is repetitive work and does not need to spend a lot of manpower and material resources, it must take time.

It can range from a few years to as many as ten years.

Moreover, it is also a troublesome thing to apply for a new drug to be marketed.

注册检验（60-90个工作日）——受理（5个工作日）——补正（30个工作日）——初审（40个工作日）——技术审评——综合审评…………制证送达。

Everything goes well, and it will take seven or eight months at the earliest.

On the other hand, the approval of Chinese medicine is stricter than that of Western medicine!

When Hu Mingming heard this, he looked at him with a half-smile, "Yes, but it's very difficult."

Chen Xiao poured him a glass of water, "Please advise."

Hu Mingming: "You can buy a drug (subsequent patented drug) that is about to be launched, and make some adjustments in the disease, which can save a lot of effort..."

Chen Xiao nodded,

This is a way,
Go back and ask someone to search for similar antidepressants (which have already obtained priority approval qualifications),
Spend the money and save time.

Seeing that Chen Xiao was thinking, Hu Mingming couldn't help pouring cold water on him, "Mr. Chen, the method is good, but it costs a lot. You must know that a lot of money and time have been invested in all new drugs that have reached the clinical stage. The transaction units are based on billions of calculations."

The implication is, you little arms and legs, you should go through the process honestly.

Chen Xiao smiled slightly when he heard this, "Dr. Hu really surprised me. I read the news before, what GlaxoSmithKline (GSK) acquired a new hemangioma drug (Sierra Oncology) for US$19 billion, and Gilead acquired a new liver disease drug for US$17 billion. (bulebirtide)... I thought they were all so expensive, but the domestic ones are cheaper."

Hu Mingming was dumbfounded,
The other party's tone is so loud?
Bragging or real?

When I met him a year ago, wasn't he still looking for a direction to start a business?

Dare to buy new drugs so soon?

Seeing that he didn't seem to believe it, Chen Xiao continued: "Thank you, Dr. Hu, for your guidance. You have a better understanding of the domestic market. Can you tell me about the new antidepressant drugs? It's fine if it's less than [-] million."

This tone completely suppressed Hu Mingming, and he smiled dryly, "Mr. Chen is so courageous, [-] million is not a small number."

Chen Xiao: "I forgot to introduce to Dr. Hu just now. The new factory I invested [-] million in Zhangjiang is under construction and will be completed by the end of the year."

Hu Mingming completely changed his attitude and smiled more, "Haha, Mr. Chen really doesn't show his face..."

Wanting him to start a business, he begged his grandma to sue his grandpa, so he brought in 2000 million investment.

The hardships in it are not enough for outsiders.

As a non-drinker, he drank 10 cups for what the investor said was "a cup for [-] yuan".

directly fell unconscious,
The next day, he still regretted that he hadn't practiced his drinking capacity well in advance, and he could drink forty glasses.

I knew there was such a local tyrant by my side,
What are you doing pretending to be the grandson?
Just hug your thighs.

Chen Xiao shook his head: "Business is inherently high-risk and high-return. When you see an opportunity, you have to go all out...Let's not talk about this, new drugs..."

Hu Mingming cheered up, "Yes, new drugs, almost all antidepressants in our domestic market are developed by multinational pharmaceutical companies, and the products of local pharmaceutical companies are mainly generic drugs."

Chen Xiao nodded.

Mingming Hu: "According to incomplete statistics from the health client of Renren Daily, there are already 17 Class 1 innovative drugs in the field of depression research and development in China that are in the approved clinical stage or above, and there are even more applications. Counting over a thousand."

Chen Xiao understands that the focus should be on the clinical stage and above, "Which companies are developing these 17 drugs, and is there any possibility of selling them?"

Hu Mingming: "You can rest assured about this, because the research and development of drugs in the neurological field is costly, time-consuming, and difficult, and the first-generation and second-generation antidepressants have serious side effects. What a problem."

Chen Xiao understood, and glanced at Hu Mingming, "What has Dr. Hu been up to lately?"

Hu Mingming hesitated for a moment. He guessed that the other party should want him to handle this matter.
"Well, no one invested in the company, and it is going to close. The next step is to find a job and pay back the money."

Chen Xiao sighed.

Apparently, the venture signed a guarantee contract at the time.

If you are bankrupt, you have to pay back the money.

Investors are smart now.

Don't do business at a loss.

"In this case, Dr. Hu, I will say this..."

Since the other party is familiar, let me help you as a reference.
Choose an experimental drug with a similar molecular formula and a reasonable price, buy it, modify it, and go through the following process.

Hu Mingming agreed, "Okay, Mr. Chen, I will teach you more in the future."

Chen Xiao got up and shook hands with him, "Learn from each other."

After Hu Mingming left, Chen Xiao looked at his watch,

There was still a little time before the second game, so I asked the waiter to clean up the table and order drinks again.

Picking up a book in the coffee shop, he flipped through it casually.

"Journey of Science"

Judging from the reviews, it seems to be pretty good. It has won a lot of awards, both domestic and foreign, and it is a global bestseller.

See the content belongs to popular science books,
I was going to flip through it casually to pass the time,
I didn't expect it to be very interesting to write,
It tells the story of the ups and downs of the scientific world in a colloquial way.

……

It wasn't until Han Chunlei arrived that Chen Xiao woke up.

The book is halfway through.

"President Chen, I'm sorry, I'm late."

Chen Xiao closed the book, "It's okay, I just arrived too."

When Han Chunlei saw the title of the book, his heart moved, and he said, "The Journey of Science, this book is very good. After reading this book, we can understand how scientists work and what drives them to desire knowledge? "

Chen Xiao: "I'm a layman in science, and I can only read some popular science books and articles."

Han Chunlei complimented: "I admire Mr. Chen for taking time out of his busy schedule to study."

After chatting for a while, and returning to the business, Chen Xiao asked, "Did Manager Ye tell you my request?"

Han Chunlei is Ye Mian's senior brother and works in a pharmaceutical factory.

Quit your job now!

Han Chunlei nodded, "I said so."

"Is it difficult?"

Han Chunlei pondered for a while, "It's not very difficult, but the effect is probably not satisfactory."

Chen Xiao: "First of all, we must ensure safety. As for the effect, there is no need to force it."

The antidepressant effects of type I serotonin are striking enough.

Type II serotonin may cause a world sensation,

In this case, it must be disguised.

Fortunately, most of the raw materials of type II serotonin are tonics, so Chen Xiao asked Ye Mian to find an industry insider and commission him to develop a health product.

The requirements are very simple. First of all, all the materials are used. The materials needed for type II serotonin must be included in the health care products.

Even if it's only 0.1 grams.

Second, health products must have no side effects.

As for the effect, it depends on fate.

Han Chunlei smiled knowingly, "In that case, no problem."

I secretly scolded the profiteers in my heart,

He felt that he had seen through Chen Xiao's purpose,
The huge interests in the hot eye health care products market, want to make a fortune.

The reason why all these messy ingredients are required to be used must be for the later publicity effect.

Take a look at our products, Polygonum multiflorum, Red deer antler, Scrophulariaceae, Angelica... which one is not a great tonic?
Not to mention the addition of so many things together, the effect is definitely leveraged.

Chen Xiao: "Okay, is one month enough?"

Han Chunlei: "If there is no requirement for the effect, one month is enough."

Chen Xiao: "Okay, first pay 10 yuan as a deposit, after passing the approval of the Food and Drug Administration, the rest will be paid in one lump sum."

Han Chunlei smiled wryly: "Mr. Chen, this food and drug approval...is not a simple matter. Sometimes, it is not even a technical problem."

Chen Xiao: "In this case, 30% will be deducted as a guarantee. Once the Food and Drug Administration approves it, it will be issued immediately, and an additional 30% bonus will be issued. If it is a non-technical problem, Party B will not be blamed. )."

Han Chunlei suddenly laughed, "No problem, Mr. Chen, leave it to us. You can rest assured that the quality will be fine. Let me confirm again. Are you really not asking for curative effect?"

Chen Xiao pretended not to care, "Health care products, everyone knows that their main function is psychological comfort. As long as we have no side effects, they are good health care products."

Han Chunlei took advantage of the situation and asked, "Can this be written in the contract?"

Chen Xiao looked at him with a mentally handicapped look.

Han Chunlei came to his senses and immediately apologized, "I'm sorry, Mr. Chen, I was the one to be abrupt."

Didn't Chen Xiao look at Ye Mian's face, so he rushed to this sentence and left the picker directly.
So fucking unprofessional,
"Old Han, we just met each other, so we can't talk about trust or distrust, but Ye Mian is recognized by everyone. As a middleman, I think there is no problem."

Han Chunlei apologized again, "President Chen, I'm sorry, professional habits, I'm really sorry."

Chen Xiao: "Old Han, let me say it again. It's a gentleman's agreement between you and me not to have curative effects. To the outside world, not only can't you say it, but you have to talk about the effect of this health care product."

"understand."

Chen Xiao: "Okay, you should also raise your own requirements. Don't let me say that you don't require results, so you should have very low requirements. Let's do this. In the end, according to the actual results, if the results are good, I will give you extra rewards."

Han Chunlei promised: "Don't worry, we put in 200% effort, and you will definitely get your money's worth."

"Hopefully."

……

After Han Chunlei left, Chen Xiao made some calculations.

There are substitutes for type II serotonin,

Next comes the production stage.
With the current level of development, fully automated production is not difficult.

The whole process is controlled by computer, avoiding the mistakes of manual operation.

All he needs to do is to customize two sets of systems. On the surface, the No. [-] health care product (Han Chunlei's model) is produced, and the type II serotonin is actually produced.

This is not difficult for manufacturers.

After all, the control systems are all ready-made, how much to add, the order to add, the way to add...all can be set by yourself.

He got up and went out from the cafe, and received a call from Ye Mian on the way,
"Mr. Chen, did Lao Han make you angry?"

Chen Xiao shook his head: "No, just a little thing."

Ye Mian: "He's a bit of a bookworm. He just started his own business and doesn't understand anything. Don't argue with him."

Chen Xiao: "Not at all."

Ye Mian reported to work: "Gao Yiming is here. After reading the drawings you gave, he found that there is nothing to change."

"That's good, can it meet the requirements of the plan?" Chen Xiao thought that what "Wasteland World" provided must be correct.
It is only possible that the requirements are too high, and the actual technology cannot meet them.

Ye Mian: "Gao Yiming said there is no problem, the feasibility study report has been compiled."

Chen Xiao: "That's good, he is an expert, since he is sure, then do it with confidence, what are we going to do next?"

Ye Mian: "We are going to invite experts to conduct environmental impact assessment and write an assessment report. At the same time, we will also invite the geological department to conduct geological exploration and issue a geological report for detailed survey. Gaogong is preparing to write a GMP report."

"Is it troublesome?"

Ye Mian: "It's not troublesome, it's just complicated. Recently, I have to go to the construction management department (including water, electricity, communication, etc.), the land department, the drug supervision department, the environmental protection department, the engineering quality inspection station, the planning department, the fire department, etc. ..."

Chen Xiao: "It's hard for you alone. If you can't do it, let Gao Yiming bring a team over. He has rich network resources."

Ye Mian thought for a while: "It's okay, there are more people, and we can speed up the progress."

(End of this chapter)