Chapter 322 I don’t burn incense on weekdays, and I hug Buddha’s feet temporarily——

In the Jingzhou Second Official Medical Office, in the deepest part of the medical office, there is a courtyard, which is guarded by heavy soldiers outside, and inside is a secret silkworm house.

Normally, only Zhang Zhongjing and his direct disciples Wang Shuhe, Du Du, Wei Xun, and Diao Chan are allowed to enter here...

It is also because of this that neither doctors nor patients are allowed to enter the entire official medical office.

For this reason, this place has also become the most "mysterious" place mentioned by those young doctors in the medical department.

At this moment, Diaochan was alone in the garden, in front of her, dozens of oranges had thick moss growing on their skins due to drying in the sun for more than ten days.

Diao Chan carefully put the moss into the container, and then filled it with salt water, in order to separate the mycelia on the moss.

Sieve out the soaked sundries through salt water, and filter out mycelium.

Next comes the most important step...

Diao Chan poured a bottle of red tar-like liquid into the container, and quickly stirred it with the moss.

This process is extremely tedious...

She stirred for a whole stick of incense, and the speed was neither fast nor slow, and it was always consistent.

And that red tar-like liquid is none other than the liquid extracted from wood in another process.

According to the "step diagram" left by Guan Lin, the liquid is called wood tar!

Specific steps...

It is to put the wood in a closed environment, and then bake it with a big fire. This is called "wood distillation" in the step diagram, and at the end of the dry distillation, you can see red tar-like substances, and charcoal, this red The substance is called - wood tar!

Diaochan didn't know that the main component of this "wood tar" was "wood creosote", and the dense smoke in a closed environment was wood gas, whether it was liquid or gas, it contained this "step chart" provided by Guan Lin The most critical substance in the water-methanol!
Diaochan drops into the moss, and then the substance that is stirred rapidly is this methanol.

As for the stirring of moss and methanol, it is to extract "penicillin"!
Needless to say the importance of penicillin.

Especially in ancient times, in case of bacterial infection, it was only resigned to fate.

If you can carry it down, you will escape the catastrophe, but the result of most people is often wound infection, bacterial outbreak, and death!

The emergence of penicillin solved the big problem of "bacterial infection"!
After completing the previous steps, Diao Chan has come to the last step. Thanks to her following Zhang Zhongjing for so many years, she has a deep understanding of medical and pharmacological...

But even so, she still didn't dare to be careless about every step.

At this moment, Diao Chan was gnashing her teeth. She had already prepared a filter made of black carbon and sand net, and thoroughly filtered the last liquid in the moss with a layer of black carbon to remove mycelium and other solid substances, leaving The purest liquid.

It was not until this step was completed that she freed her hand to wipe the sweat from her forehead...

Of course, this is not the complete process of penicillin extraction.

One final step is to pour the penicillin extract into a shallow dish and let it air dry.

The whole process lasted for several weeks, until at the end a dry penicillin was left.

However, this time takes too long, so according to the guidance on the "step chart", Diao Chan first tried to use the liquid on small animals...

See if infected sores in small animals improve.

Outside the door, Big Joe had been waiting here for a long time.

Speaking of which, since Da Qiao settled down in Jiangling, he met Diao Chan, a close friend who "has a similar experience", met his daughter whom he had missed for many years, and even heard that his son Sun Shao had defected to Prince Guan Si and escaped. Soochow is a land of right and wrong.

Wishes come true...

So, it was quite boring to do nothing all day long, so I simply... studied medicine with Diao Chan, but medicine and pharmacology are profound and profound, and it can be learned in a short time.

It just so happened that Guan Lin left Diaochan a volume of step-by-step diagrams and gave her a task of refining "penicillin". Diaochan was short of manpower and asked Da Qiao to help.

Of course, Da Qiao doesn't understand medical principles, and she can't help much by extracting "penicillin", but...it's relatively simple for her to use the extracted "penicillin" to try small animals.

It's just that, in this way, it's only been a month, and Da Qiao's hands are covered with the blood of "little animals".

You must know that even if Guan Lin left behind the specific steps of "extracting penicillin by local methods", theory is theory and practice is practice, which cannot be generalized at all.

For example, along with penicillin, there is also a substance called "patulin". Like penicillin, patulin is produced in molds that parasitize on the surface of fruits.

Penicillin is antibacterial, and patulin is more antibacterial than it;
Penicillin is soluble in water, and patulin is also soluble in water.

But the biggest difference between the two is that penicillin is an antibiotic, while patulin is a toxin, and the final refined results cannot be distinguished by the naked eye.

Of course, according to Guan Lin's memory, it has been mentioned in the step diagram to use "orange and trifoliate fruit", which are not preferred by patulin. When selecting strains, try to choose green strains.

Actually, there is one more...

The safest thing is to train two generations...

But this was completely unrealistic in ancient times, and there was no condition for two generations of incubation.

The difference between "penicillin" and "patulin" is actually just one of the many pitfalls in the process of refining penicillin...

Otherwise, there would not be a large number of big animals that died in Diao Chan's hands.

"The previous three white rabbits are all dead...the potion that was applied yesterday, just now...all died...they look miserable."

Da Qiao took the latest vessel containing "penicillin" and reminded Diao Chan softly.

"So fast?" Diao Chan bit her lip slightly...

After trying lots of rabbits, she discovered a serious problem.

If the penicillin is not used correctly, it will die instantly.

This is because "penicillin" was never pure enough or mixed with impurities in the process of mentioning it...

In case of infection, hard resistance is better than trying crude penicillin...

After all, there is still a chance to survive hard resistance, and trying crude penicillin is undoubtedly a race against death!
"Have you failed again?" Diao Chan sighed helplessly.

In fact, she not only tried this method of refining "penicillin", such as mixing moss with rapeseed oil, mixing it with black charcoal powder, wrapping it in gauze, and washing it with spring water.

Another example is to grind rice into juice and mix it with taro juice as a culture medium, implant Penicillium and culture it for seven days, then filter it with filter cotton, add rapeseed oil, use the water under the oil to dissolve penicillin, and filter again...

But no matter which method she used, it seemed that she had failed.

Even, not only is it impossible to save people, it can even be fatal!
"Alas..." Thinking of this, Diao Chan felt that the past month or so had been wasted.

"There was a red rabbit whose wound healed, and there was no more abscess..."

Well…

Following Da Qiao's words, Diao Chan's originally sluggish and annoyed mood suddenly changed completely...

"What about the rabbit?"

"It's... still in the silkworm house! I saw it just now, and I can already jump..."

"I'll go and see..." Diao Chan became excited, as if at this moment, everything she had done these days suddenly had meaning.

It also proves that the "step chart" left by Mr. Yunqi is effective, and it is possible to heal the terrible "abscess" of this era!

...

...

In Shouchun City, Cao Cao has returned.

Outside the city gate, except for Cao Zhen and a few riders, no one greeted him, and no one even knew that Cao Cao returned today.

Two rows of Huben sergeants lined up on both sides, and Cao Cao came out of the carriage dignifiedly.

It's just that, after all the fatigue along the way, this old man over 60 years old still couldn't bear it physically.

He is no longer the Prime Minister Cao who used to gallop on horseback, with the ambition of "general conquering the west"!
Cao Zhi supported his father, while Cheng Yu walked last.

"Prime Minister."

Seeing Cao Cao, Cao Zhen immediately went up to meet him.

Cao Cao stopped in his tracks, revealing a pair of tired eyes, "Zidan, tell me, is Huainan safe?"

"Thank you Prime Minister Huwei, the Jiangdong rats dare not come!" Cao Zhen replied with his hands clasped. When he said this, he slightly raised his eyes and glanced at Cao Zhi, and saw that although Cao Cao was very weak, he still cared and loved his son, even the weight of his body. Not willing to press on Cao Zhi's side.

Such a loving move made Cao Zhen feel great worries for Cao Pi.

However, this worry only lasted for a moment, he quickly raised his hand and said softly: "There are still a few things to report to the prime minister."

"Say!"

Cao Cao sat at the tree stump beside him, listening patiently to Cao Zhen's report.

Cao Zhen said truthfully: "The first thing is that I just received the information that Zang Ba, the lord of Langya, has led his troops to Nanyang. Besides, these soldiers' families are also moving to Nanyang in batches."

Although it was to clarify the facts, this incident made Cao Zhen faintly worried.

"I don't intend to let Zang Ba be the lord of Langya again. As long as he can block the offensive of Guan Jiashiro and stop the Jingzhou soldiers from the gate for Gu, I plan to seal the whole Nanyang to him... let him do it." Lord of the Southern Capital!"

This…

Cao Cao's words made Cao Zhen feel a deep compromise subconsciously.

How can a corner of Langya be compared with the vast Nanyang? Nanyang has rich fields and is the economic center of the North and Central Plains. Emperor Guangwu started here!
——"Nanyang...Nanyang, the prime minister has conceded so much, is the prime minister afraid of that Guan family Shiro?" 』

Don't wait for Cao Zhen to ponder...

Cao Cao's words came out again, "Back then, when I occupied Yanzhou alone, I was hostile to Yuan Shu and Lu Bu, so I called Liu Bei to Xuzhou and let him stay in this military buffer zone in the middle. Xun Lingjun taught the lonely..."

Speaking of this, it seems that suddenly, the voice and smile of an old friend appeared in Cao Cao's mind.

His sonorous and powerful words that helped Cao Cao dominate the Central Plains also emerged:
——"This is a plan to drive away tigers and devour wolves!" 』

This made Cao Cao suddenly fascinated...

"It turns out that the prime minister has already deployed..." Cao Zhen continued, "Just yesterday, General Xiahou sent another urgent letter from the north. Under the order of widowhood, another [-] new recruits were recruited! Now training is being stepped up, and the rescue will come within a month Going south..."

Hearing this, Cao Cao nodded slightly, not revealing his joy and anger.

Thirty thousand soldiers, although the number is quite a lot, but they are recruits...

In today's current situation, what Cao Cao lacks the most are veterans, experienced veterans...

The 3000 veterans, each of whom does something good, can train 3 recruits to fight immediately, but without these [-] veterans, the recruits are nothing but loose sand.

But now...

Cao Cao's trump card army "Tiger Leopard Cavalry" and "Runan Soldiers" were burned to death, shot to death, surrendered, and rebelled. There are not many veterans under Cao Cao who can really entrust important responsibilities !
"Forget it..." Cao Cao pondered for a moment, as if he had made a certain decision, he immediately ordered: "Tell Xiahou Yuanrang to hand over all the 3 recruits to Pang Lingming. Zhongguan Yu has kept that Guan Yu from recovering so far. This is a great achievement in preserving Xiangfan, and he should be rewarded. In addition, he was named General Zhennan, with two thousand food guards! Tell him that as long as he can keep Xiangfan, he will have a lot of weapons in his hands Canonization, everything can be given to him!"

With Cao Cao's canonization in this way, Pound jumped from a miscellaneous general to "Siping" and "Si'an" generals, and became one of the generals of the four towns, only one rank away from Zhang Liao and Zhang Wenyuan's "Generals of the Four Expeditions". class.

This is enough to show that Cao Cao attaches great importance to Pound.

Not to mention the "Lord of Nanyang"!
This is a huge pie!
But Cao Cao was also helpless.

After the death of Man Chong, Wen Pin, and Le Jin, Li Dian was captured, and Zhang Liao's whereabouts are unknown. Under the current situation, it is time to employ people!
"Well..."

Cao Zhen hurriedly cupped his hands, "At the end of the day, I will send someone to pass the order to the prime minister, let Shang Shutai draft the canon, and the emperor will stamp the seal and ribbon, and then ask General Xiahou to hand over all [-] recruits to General Pang De."

Cao Cao squinted his eyes, he pondered in his heart.

——"Xu Gongming lost first and then won, and Zixiao just woke up. The situation in Xiangfan is all in the hands of Pang Lingming!"Ling Ming, don't let Gu down! 』

Cao Cao is extremely important and trusts Pound now, just like he unconditionally trusted and reused Zhang Liao and Zhang Wenyuan before.

Having said that, Cao Cao got up slowly, had almost rested, and was about to go into the city.

Cao Zhen reported again, "Prime Minister, there is one more important matter."

"Say!"

"It's General Wen Yuan, he's back!" Cao Zhen hurriedly told Cao Cao the news of Zhang Liao's return.

That's the sentence, Cao Cao, who was tired at first, suddenly raised his spirits... He threw Cao Zhi away, and his eyes widened. If the eyes were narrowed just now, they are widened now The pupils of the eyes are tiger eyes...

It seemed that Zhang Liao was safe and sound, making Cao Cao feel like a new life in an instant.

"Where is Wenyuan?" Cao Cao asked quickly.

"General Zhang has many sores all over his body. According to him, he fell into the fat water..." Cao Zhen explained in detail: "However, General Zhang has treated these wounds by himself and branded them with a branding iron to stop the bleeding."

"Lead the way ahead, take Gu to see Wen Yuan..." Cao Cao had no patience to continue listening, and immediately told Cao Zhen that he was eager to see Zhang Liao's return.

Cao Zhen hurriedly led the way...

But after walking a few steps, Cao Zhen hesitated again and again, but still couldn't help turning around, and said to Cao Cao, "Prime Minister, there is something that 'Zhen' must tell the Prime Minister."

"What's the matter? It's more important than Gu Jian Wen Yuan!"

"It's very important." Cao Zhen emphasized his tone, and his tone became meticulous: "General Wen Yuan came back from an injury, and the last general talked to him and asked what happened to General Wen Yuan and what happened. In other words, he talked about him...so, the general was a little worried, for fear that someone would deceive General Wenyuan, so he sent someone to investigate along the way General Wenyuan came back!"

"What's the result?" Cao Cao's footsteps stopped, and he was suspicious by nature. Hearing such words, it was inevitable that the doubts in his heart would not be aroused.

"The general found out that General Wen Yuan went to Bagong Mountain. Similarly... there was another person on Bagong Mountain. After the general investigated, he found out that it was the young general of Soochow——Ling Tong! The general felt that I Great Wei and Eastern Wu are in the same situation, how could General Wen Yuan..."

When Cao Zhen said this, Cao Cao was furious. He subconsciously raised his hand and slapped Cao Zhen down.

"roll--"

Cao Zhen woke up suddenly, he knew that what he said just now... probably made the prime minister aware of the provocative intention.

Facing Cao Cao who was furious, Cao Zhen didn't dare to explain any more, and retreated scramblingly.

After Cao Zhen left, Cao Cao's tiger eyes loosened slightly, and the anger just now dissipated invisible.

He gave Xu Chu a look, and Xu Chu approached Cao Cao.

Cao Cao whispered, "Spread the story of Gu Shanzidan's slap..."

Xu Chu understood immediately, and quickly cupped his hands, "Prime Minister, don't worry."

Turning around to arrange.

Cao Cao quickly stopped him again, "Wait", his voice continued, but it became a lot softer and more cautious, and his tone also added a bit of suspicion and hoarseness.

"Fang Cai Zidan said that Wen Yuan and Eastern Wu General Ling Tong appeared together on the Bagong Mountain. You should investigate this matter, and send trustworthy Huben soldiers to investigate, but it must be done secretly—— "

As soon as this remark came out, even Xu Chu was taken aback for a moment, and he raised his head to look at Cao Cao in surprise.

As if, in an instant, the one he was most familiar with, Prime Minister Cao, who was suspicious by nature, came back again, just like the previous sentence, "I would rather bear the world's people than the world's people blame me!"

Even if the target this time is Zhang Wenyuan, Cao Cao is the same as before.

At this point in the order, Cao Cao turned his face to the other soldiers, and his tone of voice returned to the most urgent concern for his subordinates.

"Lead the way ahead, hurry up, lead Gu Jian Wen Yuan—"

After saying this, Cao Cao seemed to think of something again, he looked back at Cao Zhi again, and added, "Zijian, then Sima Zhongda, you go to interrogate, whether to kill or cut, it's all up to you—"

Having said that, Cao Cao didn't hesitate any longer, got on his horse, and the horse took a step that he didn't recognize, and walked away.

...

...

Jiangling City, Jingzhou Second Official Medical Office.

Guan Lin just arrived here.

He didn't stop, and directly took Zhang Xingcai, Shiwu... and Zhang Zhongjing, who came late, to the secret room in the back hall.

In the courtyard, there are a few poor rabbits who were injured by whom, and who did not know how the wound was infected!

Of course, besides the rabbits, there are a few dogs...as well.

They are the losers in the "penicillin" extraction.

"It looks pretty good..."

Seeing the rabbits and dogs here, Guan Lin was quite relieved, thinking that... penicillin was a great success.

Unexpectedly, at this moment, Diao Chan and Da Qiao hurried out of the house.

"And a huge success..."

Diao Chan pointed to a red rabbit in the rabbit cage, "Except for it, all the rabbits and dogs here are newly replaced, and have never been treated with medicine..."

what…

Guan Lin was startled, and quickly asked: "What does Senior Sister Ren mean... What about the other rabbits and dogs?"

"They're all dead..." Diao Chan said with some frustration and regret.

At this time, she pointed to the red rabbit again, "But fortunately, it... seems to have come back to life, and the sores have also healed! This at least proves that this method is feasible!"

this…

Hearing this, Guan Lin realized a serious problem.

This special meow is "I don't usually burn incense, but hold Buddha's feet temporarily"...

Guan Lin found that he was still too naive. It took only one month to extract penicillin and use penicillin to heal the wound infection.

Thinking about this...

Guan Lin looked up at the red rabbit that was jumping around because of the healing wound, and couldn't help but feel emotional.

——"For penicillin, my father's 'face' shouldn't be so red, right? 』

——"If this is the case, then you can only follow the second plan, and you have to use the 'ultimate move'!After all... I still have to let 'you' show up! 』

...

...

(End of this chapter)

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