This doctor has a system

Chapter 150 148. I'll Get Someone to Drive Him Out Immediately
"That's it. I hope you can mention our products when you make a report at the conference." Samuel said the purpose of this trip, but Gao Feng guessed it just now.

"I'm afraid it won't work. Your FDA application hasn't been approved yet." Gao Feng was very cautious, "Besides, you may have found the wrong person. I'm a soft-spoken person. I'm still a doctor in respiratory medicine, and my specialty isn't right for me."

"No, no, you are too modest." Samuel said, "You don't know us, that is, the gringos in your mouth. The most you hear these days is your name."

"The catalytic product you developed is really useful. Don't you know that Roche Pharmaceuticals in Switzerland is already planning to sue Novartis Pharmaceuticals in court on the grounds of unfair competition." Samuel revealed a little news to Gao Feng, "Other pharmaceutical companies are also watching, and I always feel that it will be very lively later."

Gao Feng really didn't know this news, he knew very little about foreign information.

"However, this seems to have little effect on us. If it doesn't work, we will give up the Swiss market." Gao Feng said easily.

"That's not enough. Roche Pharmaceuticals only released news to test it out. They must not be able to do enough to file a lawsuit."

"Now in the preparation of monoclonal antibody drugs, what you said is very useful." Samuel continued to persuade, "We don't need your endorsement, we just need to mention our drug at the end."

"This is the first product developed using the catalytic substrate you synthesized, and our publicity is beneficial to both parties."

"The company can offer 150 million yuan." Samuel began to take a money offensive. "Two well-known scholars have agreed to help us promote it at the Satellite Conference."

Samuel whispered 2 names.

"Them? Then your company really didn't lose money." Gao Feng was a little surprised, "That's fine, I agree to this matter, and I will mention it at an appropriate time."

"Thank you so much!" Samuel quickly shook hands with Gao Feng. This result is worth his special trip today.The company has high expectations for the recombinant human tumor necrosis factor receptor-antibody fusion protein type II. Once the FDA approves it, it will first be launched in the United States and Europe, followed by the huge market of Huaguo.

Samuel's task is to promote this drug here in advance. Through this academic exchange of the International Pharmaceutical Federation, let these experts and scholars who formulate the guidelines understand the role of this drug, so that future work can be carried out better.

"Just mentioning 150 million?" Hu Jiaran couldn't help expressing his opinion when he returned to the hotel room, "These foreigners are really rich."

"What is this little money? When the FDA approval comes, their company will definitely make a lot of money, and then they will spend more money on publicity," Gao Feng said.

"It's just too expensive." Hu Jiaran was worried about the pricing, "How can ordinary people afford it?"

To put it cruelly, the research and development of most drugs may never be for the general population. These multinational pharmaceutical giants invest real money in research and development, and the first pursuit must be profit.

Enterprises that cannot produce economic benefits will definitely be eliminated by the market immediately, so Gao Feng never dislikes these companies' pursuit of interests, as long as the method is appropriate.

In any case, it is always a good thing that a drug is developed. Once the patent period of the drug expires, its price will definitely be greatly reduced. At that time, it will not be so out of reach for ordinary people.

Today is the opening ceremony of the conference. I have to say that the United Drug Association is worthy of being a world-class association. All the guests invited are domestic and foreign experts, and even two academicians have come. The lineup is quite luxurious.

Academician Bao is on the list. He has been focusing on targeted therapy for lung cancer. This time, the third-generation targeted drug osimertinib has been approved for marketing in China, and pharmaceutical companies specifically asked him to come to the platform.Osimertinib, as a third-generation targeted drug targeting egfr gene mutations, has a definite curative effect. Compared with first- and second-generation drugs, it has a very prominent effect on patients with distant organ metastases, such as brain metastases.

Gao Feng stepped forward to say hello to Academician Bao, "It's you, Gao Feng." Academician Bao showed a smile on his face, "Did Director Shen bring you here?"

"No, I came alone." Gao Feng replied.

There was a person next to him who should be the organizer of the conference, "Old Bao, we invited Mr. Gao Feng to give an academic report."

"Oh, I remembered. The article you published on the preparation of monoclonal antibodies in Natural Medicine is very well written." Academician Bao praised Gao Feng a few words, "Young people have performed well, keep up the good work!"

Today, all the big names are present. Professor Mike from Halfaria Biological Laboratory in the United States talked about gene therapy.

Genetic engineering technology is used to introduce normal genes into patient cells to correct defective genes and cure diseases.The way to correct it can be to repair the defective gene in situ, or to transfer a functional normal gene into a certain part of the cell genome to replace the defective gene to play a role.

The target cells of gene therapy are mainly divided into two categories: somatic cells and germ cells. Today's gene therapy is limited to somatic cells.Germ cell gene therapy is the direct introduction of normal genes into germ cells to correct defective genes.In this way, not only can the genetic disease be cured in the present age, but also the new gene can be passed on to the offspring of the patient, so that the genetic disease can be cured.However, germ cell gene therapy involves many problems and the technology is more complicated. Therefore, more somatic cell gene therapy is used nowadays.

"We have applied this technology to mice with genetic defects, but the effect is not very satisfactory. The survival rate of mice introduced with normal genes is very low, and some of them have acute organ damage."

Although this technology is very immature, it still opened Gao Feng's eyes. The things introduced by Professor Mike are very cutting-edge. He is a top scholar in bio-genetic engineering. Usually, he would never have the opportunity to hear such a great person give a lecture.

Monoclonal Drug Lecture Hall.

"Next, I will invite Teacher Gao Feng. Teacher Gao Feng is currently a doctor in the Respiratory Department of the Provincial People's Hospital..."

Gao Feng's conference introduction stumped the host. They were all with the title of expert or professor, or they were the organizing committee or deputy organizing committee of the association, or at worst they had many positions.Gao Feng's introduction interface was very clean, and he just wrote one sentence: Master's degree, graduated from nm Ancient Medical University, and is now a respiratory doctor at the hn Provincial People's Hospital.

"Next, I would like to ask Mr. Gao Feng to bring us: the prospect of monoclonal antibody drug research and development."

To the surprise of the host, the applause below was quite warm.

"What is this person's background?" the host asked softly to the colleague next to him, "Such a young scholar is rare."

"Don't you know?" The colleague looked surprised, "The catalytic substrate that has been very popular in our industry recently is made by him, and he is definitely a bullish figure in the future."

"That's him?" The host responded, "I didn't match the number, I always thought he would be older."

"Antibodies are secreted by plasma cells transformed from B lymphocytes, and each B lymphocyte line can only produce one type of antibody specific to a specific antigenic determinant. The antibody produced from a single cell line is called a monoclonal antibody (McAb), or monoclonal antibody for short."

"During the formation of autoimmune diseases, B cells play an important role. CD20 is the surface antigen expressed in the process of the first B cells to mature lymphocytes. Participating in regulating the growth and differentiation of B cells. Lifenab (Morohua) is a mouse churching monolon antibody against CD20 antigen. It is the first tactical antibody approved by FDA for clinical treatment. . After entering the human body, it can be combined with the CD20 specificity to cause B cells to dissolve, thereby suppressing B cell proliferation, including inhibiting cell growth and changing methods to kill lymphoma cells. "

It was the first time for Gao Feng to give a lecture in front of so many people, and he was still a little nervous, but he calmed down after speaking.

"I found during the experiment that changing some experimental steps can make the final antibody concentration"

"Okay, my report is over, thank you all."

The host quickly summed up, "Teacher Gao Feng just gave us the following aspects..."

"Is there any teacher who wants to ask questions? If not, we will go to the next session..." Before he finished speaking, he raised a dozen pairs of arms.

"It seems that everyone wants to consult Teacher Gao Feng with a lot of questions. Let's choose one, um, this teacher." The host handed the microphone to a blond foreigner.

"Hello, Mr. Gao Feng, I'm Aldrich from Mylan Pharmaceuticals. I would like to ask if we are willing to provide the liquidated damages incurred by you and Xinhua Pharmaceuticals for breach of contract authorization, can you provide us with the catalytic substrate?"

"This...I'm afraid it won't work." Gao Feng now understood why there are so many people below, and all co-authors are from pharmaceutical companies. "The main issue is the production capacity. We are a small company and cannot supply everyone on a large scale. I am really sorry."

"This is too unfair. Only one pharmaceutical company in a region can obtain this substrate. In this way, we are completely at a disadvantage in the development of monoclonal drugs." Someone complained, and his words resonated with most of the people present.

"That's right, their final profit is several times that of ours, so how can we play this?!"

"I think this has involved unfair competition and monopoly!"

"For the health of all mankind, I think Teacher Gao Feng should provide this thing for free." A Smecta said, and the people next to him quickly moved away from him.

"Fuck, don't talk nonsense." A person in charge of Bangziguo Pharmaceutical Company was anxious, "I'm sorry, Professor Gao Feng, this person is a lunatic, I'll have someone kick him out immediately!"

The venue became very lively.

"Okay, that's all for today's question, thank you all." Gao Feng put down the microphone.

"Then we invite the next scholar from California," the host hurriedly said, the noisy venue had already attracted the attention of the participants outside, and everyone seemed to want to go inside.

When Gao Feng stepped off the stage, a large group of people rushed towards him, and Hu Jiaran hurried up, "Everyone, please make way, the place is too small, if there is anything, you can make an appointment with Teacher Gao Feng in advance."

Fortunately, Gao Feng's physical strength is very strong, and he led Hu Jiaran out of the encirclement.

"Who the hell said that foreigners are polite." Hu Jiaran was very angry, his feet were stepped on several times by a few foreigners, and it would still hurt.

"When I was at home, not so many people contacted me." Gao Feng was also a little depressed, "I thought it had been so many days, and everyone gave up."

"Brother Youliang has been dealing with them all the time, and someone contacts him every day." Hu Jiaran explained, "There are also a few leaders of our domestic pharmaceutical companies who asked the hospital leaders to intercede, and Brother Youliang refused."

"You book tickets now, and we'll go back early tomorrow morning." Gao Feng didn't want to stay here anymore, and all the people who came to listen to his report were people from the pharmaceutical company.
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"Gao Feng, are you in the hotel?" Xiong Huaxin called Gao Feng.

"Yes, what's the matter, brother Huaxin?" Gao Feng asked.

"My teacher wants to talk to you about something. Which room do you live in? Will this be convenient?" Xiong Huaxin asked.

What can academician Bao find for himself?Gao Feng was stunned for a moment, most likely it was about the catalytic substrate, he thought to himself.

"Brother Huaxin, please tell me the room number of Academician Bao. I have long wanted to visit his old man's house."

"Gao Feng, sit down!" Academician Bao greeted enthusiastically, "I only found out today that your catalytic substrate is so popular."

"This is Andrew from Novo Nordisk, Denmark. He insists on seeing you through me."

Andrew is a middle-aged man in his 50s. His Chinese pronunciation is very strange. The pitch of each character is above the second tone, which is very recognizable, like a duck.

"Dear Professor Gao Feng, I'm really sorry. In fact, I went to State Z some time ago, but your assistant simply rejected me." Andrew's attitude was very humble, "I heard that you are going to participate in this academic forum, so I hurried over here."

"Andrew is a good friend of mine. When I was young, several of my projects were heavily funded by Novo Nordisk. Although none of them produced any major results, our relationship has always been good." Academician Bao explained, "This time he came to the door, so I had the cheek to call you over."

"You can talk about whatever you want, and I won't get involved in the rest." Academician Bao led the students away without hesitation.

Academician Bao Gao Feng understood what he meant. The general idea was that when I was young, I prostituted them for free. Now that they come to me, I am too embarrassed to refuse, but you can kill them severely.

"Mr. Andrew, although we have not signed a contract with any Danish pharmaceutical company, we are limited by the production capacity. I'm afraid." Gao Feng quickly made up his mind. Academician Bao couldn't help but give them face. The other party's support for them is quite strong. If he refuses, how can he explain to Director Shen when he goes back.

"Please help me a lot!" Andrew said impatiently, "We can be at the end, and the dose can be reduced."

"Then you should send someone to Z state again this week." Gao Feng took out his mobile phone, "Look for my assistant Li Youliang, here is his contact information."

After returning to the room, Gao Feng immediately called Hu Jiaran, "Quick, pack your things, let's go now."

They had just left for a while when several people approached them. Someone knocked on the door, but no one answered.

"That's it! There seems to be no one in there."

　Thank you all for your support.

　　
　
(End of this chapter)