This doctor has a system

Chapter 153 151. You have a bright future

Gao Feng is now the celebrity in front of Director Zhao. She immediately called the secretary of the Respiratory Department to organize this multidisciplinary consultation.

"Department of nephrology and rheumatology, vascular surgery, cardiovascular department, ultrasound department, and imaging department." Gao Feng said to the secretary, "At present, we need people from these departments."

The secretary recorded it and then reported it to the medical department. This multidisciplinary consultation needs to be organized by the medical department.

The person who came this time was Director Wang. Gao Feng admired him very much. As the director of the medical department, Director Wang is usually very busy, but he still pays attention to the clinical work. He always likes to go to the front line of the clinic. He is very pragmatic.

Gao Feng reported the medical records in detail, and a group of experts expressed their opinions. After serious thinking and discussion, many experts agreed that:
目前诊断：1.抗磷脂综合征2.慢性肺栓塞3.重度肺动脉高压4.双肺炎症5.双下肢深静脉血栓6.心力衰竭新功能IV级7.I型呼吸衰竭。

In terms of treatment measures, the director of the Department of Nephrology and Rheumatology also contacted Professor Ma of the Department of Rheumatology of Union Medical College, who believed that the diagnosis of antiphospholipid syndrome in this patient was clear, and the possibility of catastrophic antiphospholipid syndrome was considered high.

Catastrophic antiphospholipid syndrome accounts for 1% of the total incidence of antiphospholipid syndrome, but the mortality rate is as high as 50%-70%. The causes of death are mostly stroke, hemorrhage, encephalopathy and infection caused by microangiopathy and thrombosis.

"Lifelong anticoagulation is recommended in the absence of significant bleeding risk."

"This patient is considered lucky." Professor Ma looked at Li Haoxuan's medical records, "He is still alive after 6 years, which means that his life should not die."

Gao Feng didn't know what to say. The patient and his family members probably wouldn't think he was lucky. Xiao Li's current state was adjusted, and he would definitely lose a lot of things in his next life.He can't run against the morning light like other young people and spend his youth recklessly. He will only be like an old man in his twilight years, and he may not be able to persist in activities for a longer period of time.

"Thank you. If there were no experts from so many disciplines to seriously study my condition, I'm afraid I would never know what the cause of my condition is." Xiao Li expressed his thanks to everyone.

"You successfully completed the task of searching for the source and gained 20 skill points."

"You have received heartfelt thanks from patients and their families, and you have gained 2 skill points."

Li Haoxuan was unlucky, he was tortured by illness for 6 years, he was lucky again, this time he met Gao Feng.

For the next week, Gao Feng put most of his energy on him.The results are very gratifying. Perhaps because of his young age, Xiao Li's symptoms were relieved quickly, his chest tightness symptoms were greatly reduced, and the edema of his lower limbs was also much better, which made everyone very excited.
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Natural editor Philip is reading an article from Huaguo.

"Gao Feng published an article in our subsidiary journal Nature Medicine some time ago, and the number of citations was very high." Philip said to his colleagues, "Now I have read this article carefully, and I feel that the quality is very high, and it obviously meets the publication requirements."

"I don't know why Ralph completely denied this, but he didn't indicate the reason in the returned manuscript." Philip looked puzzled, "The other two reviewers have greatly appreciated the article."

Ralph is a professor at Yale University and one of the many reviewers for Nature.

"Let me take a look." The colleague picked up the article and read it carefully.

"Wait a minute, I seem to know the reason." The colleague picked up the phone and made a call to the back office.

"Ralf is also doing a similar experiment, and it is said that it will take another week to confirm the final result." The colleague hung up the phone and said to Philip, "The experiments of the two are highly overlapped, which should be the reason."

"This Ralph seems to have behaved similarly before." Philip was a little unhappy, "I don't know why the magazine still chooses him as a reviewer."

"He is still very capable, and the quality of the papers he publishes is very high. The magazine does not want to lose such a person." The colleague took a sip of coffee and analyzed slowly, "What are you going to do next?"

"Of course, publish this article as soon as possible." Philip stood up, "I've decided to jump in and publish it."

"If you do this, you will offend Ralph." A colleague reminded.

"Matt, is there anything to worry about?" Philip asked back, "We were not familiar with each other before, but he has never submitted a manuscript to me."

Philip sent an email to Gao Feng: "Dear Gao Feng scholar, your paper "" (article number BD2021826194829) has been reviewed by many parties, and the subject matter meets the publication requirements of "Nature". You need to confirm this news within 3 days. --Please reply as soon as possible to avoid other problems. ---Philip of Nature Magazine."

"It shouldn't be a problem. People in Huaguo are very efficient." Philip took a sip of his coffee. "It's said that 996 is popular there. Matt, do you know what 996 is?"

Gao Feng saw the message that afternoon, and he hurried to the computer to reply.

"Daughter-in-law, my article is about to be published, the natural one." Gao Feng was a little excited.

"Really?" Li Xinyao said in disbelief, "Congratulations, Mr. Gao, tell me about your experience in posting articles when you get back."

"Don't worry, tonight, Mr. Gao, I will tell you about this experience from all aspects and from multiple angles. I promise to make you fascinated and gain a lot."

"That's how it is." Li Xinyao hung up the phone hastily, she was still in the department, but she didn't dare to let Gao Feng say these indecent words again.

If Gao Feng was there, he would definitely feel wronged. Is there something wrong with what I said?Isn't it all normal language communication?If you think too much due to personal reasons, then I have nothing to do.

Then he called Li Youliang and Hu Jiaran. Everyone must know such good news. Gao Feng was very happy.

Soon even Director Shen knew the news, "Didn't you release the satellite?" She was shocked, "When did it happen? Are you sure the article will be published?"

"The editor said next Thursday." Gao Feng said, "There shouldn't be any changes."

"Tell them not to tell other people first, and then mention this after it is published." Director Shen warned, "From the establishment of our hospital to the present, no one has published an article on nature. If your story is true, the impact will be too great. We must be cautious."

In fact, it's no wonder Director Shen behaved like this. How difficult is it to publish an article on Nature?The following speaks with data and facts!

In 2017, 803 papers were published in Nature, 702 in Science, and 327 in Cell.

According to the report of UNESCO, there were already 2013 million researchers in the world in 780, and the current conservative estimate is 1000 million.

Assuming that the 2017 articles on Nature/Science/Cell come from different research groups (many cattle research groups publish several articles a year), the ratio is about 0.018%, that is, 1.8 out of [-] researchers on average can publish CNS.

In 2017, Tsinghua University and Peking University in Henan admitted 405 students and 98.3 candidates, with an admission rate of 0.041%.In terms of numbers, it is twice as difficult to get into Tsinghua University and Peking University in Henan, which has nearly one million college entrance examination candidates in 2017.

Wuhan University has 18 academicians of the two academies and nearly 130 outstanding young scholars and Changjiang scholars. In 2017, it also published an article in Nature (Nature) and a Science.

Anyone who does scientific research knows that academicians, outstanding young scholars, and Changjiang Scholars are already very accomplished people in the scientific research circle.For them, it is still difficult to develop Nature and Sciecne.

In fact, Gao Feng's article was able to get the attention of Philip, the editor of Nature Magazine, and the reviewers, thanks to the current situation of monoclonal antibody drugs in full swing. The article described in detail the emergency pathway or the rescue pathway ("S pathway").

It was also mentioned above that it uses hypoxanthine-guanine phosphorylated nucleoside transferase (HGPRT) and thymidine kinase (TK) to catalyze hypoxanthine and thymidine to generate corresponding nucleotides, and both enzymes are indispensable.Therefore, in the HAT culture medium, the "D pathway" of unfused effector B cells and the fusion of two effector B cells is blocked by aminopterin. Although the "S pathway" is normal, due to the lack of ability to proliferate in vitro culture medium, it will generally die in about 10 days.

In the early days, people did not pay attention to the S pathway because they thought it had no value, but now many scholars have noticed the importance of this pathway in antibody screening.

Gao Feng's article just appeared at this point, and it immediately fit the sensitive point of Nature Magazine. Philip is not an unknown junior in Nature Magazine. He has been working in Nature Magazine for nearly 25 years. He has a vicious vision and has discovered many excellent articles.

Of course, the article Gao Feng published in Natural Medicine some time ago also added a lot of impression points to him, and the conditions for publication of contributions from unknown persons may be even more stringent.

"There are quite a few people working." Gao Feng came to the laboratory construction site with Hu Jiaran wearing a hard hat to check the progress.

"The project is progressing very quickly." Zhao Xingye looked up at the scorching sun, his whole body was drenched, "We have supervisors stationed here, and the quality of the project is guaranteed."

"That's good." Gao Feng felt very satisfied, "In the future, the company's revenue and output will all depend on this side, you still have to pay close attention, especially the cleanliness must meet the standard during acceptance, otherwise there is no way to put it into use."

"Okay, don't worry." Zhao Xingye quickly assured that this is the only thing in the company right now, and he can definitely keep an eye on it.

Andrew, the person in charge of Novo Nordwar, arrived in State Z today. He was already in a hurry, and Zhao Xingye only contacted him today.

"Hello, Manager Zhao, I'm Andrew from Novo Nordisk." Andrew went straight to the point, "I'm here for the catalytic substrate, and I hope to reach a cooperation with you as soon as possible."

"That's fine. Since Mr. Andrew is so direct, I won't say much else." Zhao Xingye pondered for a while, "It's 3000 million US dollars a year, at least 5 years."

"It's the same as the quotation from Boehringer Ingelheim Pharmaceuticals. This is what our boss Gao specifically explained."

"Please be sure to convey my respect to Mr. Gao Feng." Andrew heaved a sigh of relief. He was worried about being brutally slaughtered when he came, but he didn't expect to be able to enjoy the same treatment as Boehringer Ingelheim Pharmaceuticals.

"Then let's sign the contract." Andrew waved his hand, and the accompanying staff came up, and lawyer Zhao Hongyuan also stood up. The two parties need to make a detailed agreement on the detailed rules.

"It's too easy to make money." Zhao Xingye looked at Andrew's figure leaving in a hurry, feeling unreal.People sit at home, money comes from the sky, and people seem to be afraid that you don’t want it. This job is so unchallenging, I like it very much.

This Thursday is the day when the latest issue of Nature is released. Nature is a weekly magazine with 51 issues throughout the year. It is positioned as: taking into account both academic journals and scientific journals, that is, scientific papers have high news and a wide readership.Papers must not only be "outstanding scientific contributions," they must also be "of interest to an interdisciplinary audience."

Director Shen calculated the time and called his classmate in England, "Ah Qing, how are you doing? Have you bought any magazines yet?"

"I bought it, and I am going to tell you." A steady female voice came from the phone, "It is true that a scholar named Gao Feng posted an article on it, and the communication unit is yours. The corresponding author of the paper is Zhao Xianqin."

"Take some photos for me and send them here." Director Shen was a little excited, this Zhao Xianqin was so lucky, she was almost dying of envy.

"Old Zhao, come quickly, you are really lucky." Director Shen couldn't wait to call Director Zhao, "Gao Feng's article was published on Nature, and you are the corresponding author!"

"Really, I have already asked my friends in the UK, and they even sent photos. Come here quickly, and report such a big achievement to the leaders now."

"Li Xun, go to the teaching secretary, Zhang Qian, and write a text message first." Director Shen directed the number one guy under him, "Let me read it after writing it, and send it to our work group after the leaders know about it."

Director Shen waited for Director Zhao to go up to find Gao Feng as soon as he arrived, who was still giving lectures to the students, "This pulmonary embolism is most common in..."

"Gao Feng!" Director Zhao shouted, "Come on, let's go to the office building now."

"Director, what's the matter?" Gao Feng was a little confused, "What happened to the department?"

"Your article has been published!" Director Shen came over and patted him vigorously, "That's great, let's report to the leaders of the institute now."

No way, Gao Feng was a little speechless following the two directors, who seemed happier than him.

"I'm not joking." Vice President Guo didn't even drink his tea. "It's definitely nature. The nature magazine in the UK, isn't the nature magazine in our country?"

"It's absolutely true, Dean Guo." Director Shen said with a smile, "I've confirmed everything. You see, this is a picture sent by my classmate."

Vice President Guo took the phone and looked at it carefully, "It's really amazing! I really admire Gao Feng's ability!"

"The good scientific research environment of the hospital has deeply affected me, coupled with the strong academic atmosphere in the department, this further inspired me." Gao Feng said these words involuntarily.

"Hey, you baby, what do you want me to say, you have a bright future!" Vice President Guo's mouth cracked.

(End of this chapter)