This doctor has a system

Chapter 173 171. As soon as you open your mouth, scare them to tears

"I think everyone's thinking is too one-sided." Gao Feng raised everyone's spirits first.

"No, who are you?" Director Xue of the First Affiliated Hospital was not happy, "Why are we thinking one-sidedly?" He was a little dissatisfied, the young man's hair has not even grown, so what's the point of this nonsense.

Gao Feng was very satisfied with Director Xue's performance, "My name is Gao Feng, from the Respiratory Department of the Provincial People's Hospital." He was very afraid that others would not know his name.

"The Gao Feng who is so natural?" Director Hu Liang blurted out.

Wow, I have a good memory, no wonder I'm bald. Gao Feng looked at Director Hu appreciatively.

A group of people immediately whispered to each other. Director Xue of the First Affiliated Hospital originally wanted to say something to Gao Feng, but when he heard the word "nature", he couldn't open his mouth anymore.

Toads drink glue - I can't open my mouth.

Fa is naturally so domineering, even if you go to a non-professional department and yell, no one will dare to take it seriously.

"Young talent!" The director of the Deng County Medical Department exclaimed, "Everyone welcomes Professor Gao to express his opinions."

"Actually, the diagnosis of this patient is not difficult to come by, and there are many places that gave us hints." Gao Feng said in a surprising way.

Director Ji of the Provincial Medical Center stared wide-eyed, you better have real talent and learning, if you talk nonsense, my old Ji will immediately declare war on you.

"Dr. Zhou just said that the patient had hiccups. I asked the patient in detail during the physical examination, and the symptoms have not been relieved until now."

"Many gastroenterologists here, have you ever thought about why hiccups occur?"

"The occurrence of hiccups is caused by the spasm of the diaphragm. Why does the diaphragm spasm? The reason is that it is the phrenic nerve or vagus nerve that directly innervates the diaphragm. This nerve comes from the ganglion of the spinal cord root of the third and fourth cervical vertebrae, which is called the hiccup center here. The upper part is also controlled by the medulla oblongata. Therefore, any factors that affect the above-mentioned parts can cause reflexes of the phrenic nerve or vagus nerve, leading to spasm of the diaphragm and hiccups."

"The most common thing in life is reflex hiccups, such as thoracic and abdominal visceral lesions or thoracoabdominal surgery that stimulate the phrenic nerve or vagus nerve. When eating, the food passes through the end of the esophagus and stimulates the phrenic nerve;"

"The other one is central hiccups, which are generally caused by diseases in the brain that directly or indirectly affect the medulla oblongata or cervical cord. Common diseases include encephalitis, meningitis, brain tumors, craniocerebral injuries, and cardiovascular and cerebrovascular accidents."

"Speaking of which, did everyone think of something?" Gao Feng made a fool of himself, and just as he was continuing to talk, a voice sounded.

"I'm going! Forget about this." Director Ding of the provincial doctor slapped his thigh fiercely, "I just thought about neuromuscular junction disease, but I didn't think about brain tumors."

Seeing that everyone was looking at him, he couldn't help but continued, "From a physiological point of view, intestinal peristalsis is controlled by sympathetic and parasympathetic. If this happens, it should be considered that there is a problem with the parasympathetic nervous system. That is, the vagus nerve. From the vagus nerve Looking at walking, the back of the cranium passes through the neck and enters the abdominal cavity through the chest. If there is tumor invasion during the walking, it can cause the above symptoms. Retroperitoneal tumors have been excluded in the abdomen, esophageal cancer has also been excluded in line, and mediastinal tumors will also compress the trachea and The corresponding manifestations of large blood vessels should be manifested in the physical examination of neck tumors. Therefore, it may be caused by intracranial compression of the vagus nerve."

"I suggest doing a cranial MRI now to see if there is a brain tumor!"

Gao Feng is stupid, why don't you talk about martial arts, this director Ding is really a dog, do I need you to stop talking about it? ! !I have my own mouth, I can say it myself!

Gao Feng regretted that he would have known that he would not be fooling around. He just wanted to slap himself twice.He should have thought earlier that none of these directors was fuel-efficient.

"Director Ding is too right." He glanced at the other party full of resentment, "Actually, the early misdiagnosis of this patient is entirely due to the incomplete physical examination."

"During the physical examination just now, I found that the patient's neurological signs were quite obvious. He had mild deep sensory disturbance and symptoms of ataxia at the same time."

"If there was a neurologist or neurosurgeon here, I believe the problem would have been solved."

"Finally, I will boldly guess that this patient should have a posterior cranial fossa tumor!"

As soon as Gao Feng finished speaking, there was a buzzing sound in the meeting room, and everyone was whispering.

"Which expert still wants to express his opinion?" The director of the Deng County Medical and Education Department picked up the microphone and asked, but no one said anything.

"Quick! Take the patient for a brain MRI." He said to Zhou Mengli, the doctor in charge, "Hurry up and ask them to report."

More than 20 minutes later, the results of brain MRI came out, and it was indeed a tumor in the posterior fossa.

"Damn it, it's awesome!" said a doctor from a county hospital.

"Yeah, people can tell that there is something wrong with their brains just by looking at it. I have seen it several times, and I almost gave the patient a laparotomy!" The doctor in the general surgery department of the county hospital was greatly shocked.

"How many doctors in the gastroenterology department will do a professional neurological examination for the patient?" Director Ji shook his head, "Anyway, I hardly ever do it."

"It would have been nice if I had seen a neurologist from the very beginning." Director Ding felt a little regretful.

"Just kidding, a patient whose image shows intestinal obstruction can walk and jump, would you think of seeing a neurologist?" Director Xue from the First Affiliated Hospital said, "Isn't this unreasonable?"

"We still need to do MDT (Multidisciplinary Consultation)!" Director Zhao said with emotion, "It doesn't matter what the disease is, let every department come and see it."

"Strange intestinal obstruction: You easily helped Su Weiguo make a clear diagnosis, and your performance is really excellent! You have gained 20 skill points."

"Amazing four people with your skills: You taught everyone here a good lesson with your professional knowledge, and almost everyone was surprised by your performance. You got 17 skill points."

Only 3 skill points were missing, and Gao Feng felt very satisfied. Looking at Director Ding's thick hair, he cursed silently in his heart: Bald!bald!Go bald next year!

Director Ding subconsciously touched his head, just now he always felt the front of his forehead was cold, it was strange.

On the way back, Director Ji insisted on huddling with Gao Feng, "You are breathing alone, how do you know so much about other majors?"

"It's also a blind cat bumping into a dead mouse." Gao Feng said modestly, "The main reason is that my wife is a neurologist, and we often study together."

Gao Feng didn't lie, he did often study with Li Xinyao, but the content of this study hehehehehe
"You're so natural!" Fighting Chicken (Ji) couldn't help touching Gao Feng's head with his hand.

? ? ?high wind

"Haha, let me see if I can get some inspiration." Director Ji touched his head again.

"Old Ji, you are amazing!" Director Ding said speechlessly, and then he reached out and touched it.

Everyone
"Kill all directions! It's completely one-sided crushing!" Gao Feng told Li Xinyao about the experience of this out-of-hospital consultation while eating.

"As soon as I stood up, everyone was shocked. What a Mo Shangren Ruyu, your son is unparalleled in the world!"

"As soon as you open your mouth, scare them to pee! You don't know"

"The moment I mentioned the tumor in the posterior cranial fossa, no one dared to speak out. In the conference room, you could hear a needle drop!"

"That guy, the director of the medical education department of the county hospital took my hand and shook it vigorously. Professor Gao, you must come here often in the future! We can't do without you!"

"I almost couldn't come back, it was too scary."

Li Xinyao laughed so hard that she almost couldn't straighten up, "You are the only one who can blow."

"Actually, you can blow it too." Gao Feng looked at her meaningfully and said.

"roll!"
-
X Township Medical College, Laboratory.

"It's too ugly." Hu Jiaran looked at the machine in front of him with disgust, "Are you sure it can work?" He asked the engineer beside him in a suspicious tone.

"How do I know if it can be used?" The engineer replied, "Anyway, I made it according to the drawings you gave me. If there is a problem, it's none of my business."

"Why are you talking to us Mr. Hu!" Wang Liang on the side said dissatisfied, "What's wrong, you haven't put on your pants yet, so you don't admit it?"

"Hey." The engineer smiled, "That's not what I mean, why don't we run it first and see if it works?"

"Hurry up!"

Not to mention, although the machine is ugly, it runs rattly. Hu Jiaran looked at the hybridoma cell plate in his hand with beaming brows.

"Quick! Get another one out," he said to the engineer.

"It's already 6 o'clock, it's time to get off work, tomorrow." The engineer said while packing his things, "I live far away from here."

"Add 2000 yuan to you."

"It's really not about the money! The main thing is that I think you are really in a hurry." The engineer quickly went to disassemble the parts, "Besides, there is nothing to go home, just a tigress."

"Penghui, Wang Wei, each of you will lead a group of people to do automatic screening of high-throughput equipment, and other personnel who have no tasks will use this limited dilution cloning method." Hu Jiaran gave an order, "Everyone get busy, 2 There must be a result within a week!"

"Maybe everyone should go back to State Z as soon as the results are achieved." He encouraged, "As long as the project is completed, maybe we will give you extra rewards!"

Once a person becomes a leader, he will naturally awaken the skill of making big pies, which is amazing!

Soon, a week passed, and Hu Jiaran was in a daze in the corridor outside the laboratory that day, when a voice suddenly called out, "Quick, come quickly!"

Hu Jiaran was taken aback, "What's wrong?" He hurried over.

"Look! Is it this?" An employee named Wang Dan trembled excitedly holding a plate of hybridoma cells, "The growth is very good! I just did the antibody subtype identification, that's right!"

"Let's go." Hu Jiaran couldn't wait to get started. He took the kit and used the double-antibody sandwich method to identify the type of monoclonal antibody in the culture supernatant of the hybridoma cells.

"Hahaha!" Hu Jiaran laughed out loud, "According to the data of this group, repeat it twice for me." Hu Jiaran confessed, and quickly called Gao Feng.

"The seed cells are finished?" Gao Feng cheered up, "I'll be there tomorrow, and you should do the cell expansion first."

After hanging up the phone, he thought for a while, and called Qi Huiren of Xinhua Pharmaceutical, "Old Qi, what does your company think about bevacizumab injection?"

"How do you look at it?" Qi Huiren was a little confused, so, "Watch it lying down? Standing up? What do you mean?"

"I had a whim some time ago and wanted to imitate this medicine." Gao Feng said.

"Don't waste your time." Qi Huiren kindly persuaded: "It's not that simple to make a generic drug. Except that you don't need to do Phase 3 clinical trials, everything else is no different from the original drug."

"You don't have any experience in this field, so doing this is purely a waste of money."

"We have already made seed cells, and then we will prepare for cell expansion and mass culture." Gao Feng said.

"What did you say?" Qi Huiren was stunned, "Is it a fused hybridoma cell? Have you verified the antibody produced?"

"It shouldn't be wrong." Gao Feng said with a smile, "Would you like to come and see?"

"Yes! I want it!"

Qi Huiren not only came by himself, but also brought a group of people.

"Old Qi, are you kidding me?" Dai Yonghui questioned.

"You go and have a look, I can't give you an accurate answer." Qi Huiren looked impatient, and the other party asked him several times.

"It's not that I don't believe it. How should I put it, this is not that simple." Dai Yonghui was the person in charge of the generic research of bevacizumab injection before, and he led a team to work hard for nearly a year and a half. planted on the seed cells.

The synthetic seed cell subtypes are not pure enough, which leads to big troubles in the expansion and cultivation. The most direct consequence is that the produced antibodies are not pure enough, and there is no way to produce them on a large scale.After a period of time, the problem could not be solved, and the company directly cut the project.

"I think the credibility is relatively high, after all, the catalytic substrate was developed by others." Qi Huiren is very confident in Gao Feng, "Let's go and see, Gao Feng probably wants to seek cooperation, in case it is true , you must seize the opportunity!"

Qi Huiren has tasted the sweetness. The company has made a lot of money this year because of the catalytic substrate. He is full of expectations for this year's year-end award.

After Gao Feng arrived at the laboratory, Hu Jiaran reported the current progress to him in detail.

"Make another batch of amplification, and change the culture medium this time." Gao Feng explained to the latter, "You configure it according to this, there are two steps in it, you do it yourself."

Hu Jiaran's expression became a little dignified now, "Do you want to keep it a secret from everyone?"

"Yes, that's the case at the moment." Gao Feng replied: "We will definitely authorize this. I have already contacted Xinhua Pharmaceutical. Before the dust settles, don't disclose these key points."

"Separate the process from now on, and make the complete steps accessible to no one but you."

"So as not to make any fools."

"Don't worry, I have been doing this before. Some of the more important parts are all done by myself, such as the time, temperature and dosage of several key links." Hu Jiaran said, "The complete experiment log is currently only available. I can see it."

"I don't worry about your work." Gao Feng was very satisfied with him.

The next steps are actually very simple. After the cultured cells are expanded, they are transferred to a 15L disposable biological container. During the cultivation, the culture medium is added, and oxygen and carbon dioxide are introduced to allow the cells to multiply and differentiate normally to produce antibodies.

If there is no problem with this level, then the next step is to carry out multi-stage reactor cultivation.

At the same time, Qi Huiren and Dai Yonghui rushed to X City with their people.

"Why is it so windy here?" Dai Yonghui looked at the dusty scene outside in the taxi with disgust on his face.

"It's like this here all year round, who knows where the wind comes from." The taxi driver said, "Are you from Shai?"

"How do you know?" Dai Yonghui was a little surprised.

"I have a friend who speaks in the same tone as you." The driver said, "They're all kind of motherfuckers."

Qi Huiren almost laughed out loud.

　I can't do it anymore, I can't hold it anymore, I washed my face, but I'm still not clear enough.

　　I owe 3000 words today, and I will make up for it tomorrow.

　　
　
(End of this chapter)