This doctor has a system

Chapter 191 189. It's boring to make small troubles, if you want to do it, make it big!

As for the following original research drug, it and osimertinib mesylate, which has just entered the Huaguo market recently, belong to the third generation of EGFR inhibitors, and it has excellent curative effect on patients with non-small cell carcinoma with EGFR mutation.Compared with the first-generation and second-generation EGFR inhibitors, the effect on patients with lung cancer complicated with brain metastases is amazing.

But this drug requires as much as 800 skill points, and Gao Feng's current total skill points are only 760. The landlord's family really has no food left.

Moreover, compared with pirfenidone, the research and development conditions of the original research drug are more stringent, the research and development time is longer, and a lot of manpower is required. At present, it is definitely not enough to rely on Hu Jiaran's few people.

But having said that, high investment brings high returns. Once successfully developed, it will be a depth bomb, bringing economic benefits and prestige that are incomparable to generic drugs.

Gao Feng was caught in a dilemma for a while, he hesitated and then called Xiong Huaxin.

"The original drug is too difficult, and it is more suitable for you to make a generic drug." Xiong Huaxin thought about it: "Don't think too high of yourself just because you made a bevacizumab injection."

"Although the benefits of the original drug are astonishing, it has to be done. In the past ten years, the average success rate from Phase 9650 clinical trials to FDA approval for marketing in the 1 drug clinical development projects was 6.8%, and the average time required 10.5 years."

He told Gao Feng the data he knew, "So, it must be the safest to make generic drugs."

"And you have a certain reputation now. At this time, you can develop it together with universities and pharmaceutical companies. If you share the risk, they will definitely not refuse." He suggested, "The final benefit may be less."

In fact, Gao Feng doesn't care too much about income, as can be seen from his generous attitude towards those around him.He is already a billionaire now, what's the point of earning more money.

If it can cooperate with universities and enterprises, then pirfenidone seems to be a bit of a joke, and the third-generation EGFR inhibitors seem to be more suitable.After hanging up the phone, Gao Feng called Hu Jiaran, Li Youliang and Zhao Xingye over.

"This is the current situation. Let's share your opinions. Old Zhao, you are the general manager of the company. You come first."

Zhao Xingye is a bit blind now. He is the general manager of the company, but he has no right to speak about the company's business direction. He feels that he is just a gatekeeper.

"Well, I think pirfenidone is more suitable for launching." Out of prudent considerations, Zhao Xingye does not agree with the development of original research drugs, especially when he knows that the investment in it is calculated in billions of dollars.

"Ten billions?" Li Youliang was also taken aback, "If it fails, wouldn't it be a waste of time?"

Hu Jiaran also agrees with the development of pirfenidone. Multi-party cooperation has high requirements for management. How can he, a young man with no hair yet, take such a big responsibility? If something goes wrong, he will die forever .

"Since everyone thinks so, let's develop this third-generation EGFR inhibitor!" Gao Feng made a decision.

? ? ?Hu Jiaran, Li Youliang, Zhao Xingye
"I'm very confident in this, and everyone should also have confidence." Gao Feng said with a smile, "It's so boring to make small troubles, if you want to do it, make it big!"

The audience of pirfenidone is not comparable to that of the third-generation EGFR inhibitors. It is important to know that lung cancer is the cancer with the highest incidence rate in the world.

"Should I find some more professionals?" Hu Jiaran asked, "If it is multi-party cooperation, I really don't have confidence in myself. How can I, a student, play with their old fritters?"

Professionals must be brought in, even the following scientific research migrant workers will also be recruited in large numbers. It is simply impossible to start this project with the current manpower.

"I'll contact Z University tomorrow and see what they say." After Gao Feng finished speaking, he signaled everyone to end the meeting.

After leaving the gate of the community, the three of Zhao Xingye stopped, "How about we find another place to talk about it?" Zhao Xingye suggested.

"Let me tell you, he's a little bloated now." Li Youliang said, "However, the boss is indeed capable. So far, he has accomplished what he wants to do."

"Yeah, I've always had confidence in Brother Feng." Hu Jiaran poured a glass of beer for everyone, "I just don't have confidence in myself. I'm an undergraduate, so it's a bit difficult for me."

"Anyway, the company is his, so he can come here as he wants." Zhao Xingye said, "Sometimes he won't die if he doesn't hit the south wall."

"I'll keep an eye on it. If it really doesn't work then, we must stop him in time, so that all the money won't go to waste."

The three chatted for a long time, and then dispersed after reaching a consensus.

At around 9:[-] the next day, Gao Feng took the time to call Vice President Liu who was calling Z in the bronchoscopy room, telling him that he was going to continue to develop drugs, and asked if the other party was interested in it.

"I'm interested, I'm so interested!" Vice President Liu hurriedly said, "Where are you? Let's meet and discuss in detail!"

After hanging up the phone, he called the head of the school of pharmacy over, "What do you think? I think this time he means that the school should also have substantial investment. Is it too risky?"

The head of the school of pharmacy is called Dang Ruxiu. He is engaged in drug toxicology research and has no experience in drug development. this one.

"Development of drugs is definitely risky, and it depends on the type of drug." Pan Xianyi considered, "However, I have great confidence in Professor Gao Feng, who can imitate bevacizumab in such a short period of time. Injection, the ability is not something I can look up to."

"You mean it's better for the school to get involved?" Vice President Liu asked.

"Of course, if you succeed, you will make a lot of money. Money is the second priority. The key is to greatly improve the status of our school of pharmacy in the country." Pan Xianyi said out loud.

"What if it doesn't work?" Dang Ruxiu frowned, "Isn't the real money gone for nothing?"

Then you are not talking nonsense, who can guarantee that it will be successful? !Pan Xianyi complained in his heart, he is [-]% sure he will still find you?Are you pale or what?
Vice President Liu is a sensible person, how could he not understand such a simple truth, he was just weighing the pros and cons.If the risk is very high, it cannot be passed on the school committee.

After thinking about it for a while, he decided to bring Pan Xianyi with him when he went to see Gao Feng, and asked about the regulations before coming back to discuss collectively.

At the same time, Xiong Huaxin disclosed to Qi Huiren of Xinhua that Gao Feng was about to carry out drug development again, "Old Qi, don't say that brother won't help you, I conveyed the news to you as soon as possible. It's up to you."

Qi Huiren didn't dare to delay, so he hurriedly reported the news to Jiang Liangqian, the boss of the company, and the latter cheered up, "Go over there quickly, find out what's going on, and report to me directly if you have anything, this time you don't dare Pull it down again!"

"Did he make it self-confident?" Dai Yonghui said, "Is it still a generic drug this time? Which variety?"

"I know as much as you do." Qi Huiren said solemnly, "No matter what, this time there must be no mistakes." He is under a lot of psychological pressure now, and when he came, Mr. Jiang said that he would be fully responsible. This is a good thing and a bad thing. , it is gratifying if there is a harvest, but if there is a problem with the board, he will be the first to fall on him.

Dai Yonghui is very relaxed. He thinks that the last loss was due to his teammates. He is very optimistic that he can report directly to the leader this time.

"Making original research medicine?" Pan Xianyi looked incredible, "Is this possible? The investment is estimated to be more than one billion, and the failure rate is too high." He shook his head and felt unreliable.

Seeing his appearance, Vice President Liu didn't dare to say too much. After inquiring about the situation carefully, he said goodbye, "Let's go back and study it." He said.

After returning to the school, Vice President Liu summoned all the people, big and small, from the School of Pharmacy, "Professor Pan, please tell everyone about the situation."

"Everyone knows about osimertinib, right? The third-generation targeted drug that just entered China." Pan Xianyi said, "Professor Gao Feng is planning to do the same thing. He wants to use a molecule to replace the methoxybenzene of osimertinib." , It is said that it can make the activity of drugs and metabolites stronger."

As soon as his words fell, someone said, "This is not a joke. I think Gao Feng just made a generic drug and then swelled up." Lu Zhongwei, the vice dean of the School of Pharmacy, said disdainfully, "Really Is it so easy to be an original drug?"

"Hehe, how long has he been using osimertinib mesylate? How much did he spend? Does he have the strength?"

"I'm full of confidence now, but in the end I'm sure I'll be overwhelmed!"

Pan Xianyi is a little unhappy. Although he is not optimistic about this project, what you Lu Zhongwei said is too much. Does anyone say that?
"Professor Gao Feng said that he has verified the feasibility, and the probability of producing results is very high." He said.

"Who wouldn't do it if you just open your mouth? The school can't be led by the nose." Lu Zhongwei continued to output, "I'll leave it at that. If this project is successful, I'll just resign..."

"Old Lu!" Vice-principal Liu interrupted him, "Everyone is here today for a group discussion. You can express your opinions, but you must be careful with your words." Woolen cloth!
"Professor Gao Feng's imitation bevacizumab injection can bring nearly 1000 million benefits to the school every year in the future. I hope that everyone must give the other party enough respect before expressing their opinions!"

Vice President Liu's meaning is very clear, people can bring benefits and fame to the school, it's not the same as some coquettish sluts who only know how to open their mouths for scientific research funds.

Lu Zhongwei blushed, he was usually conceited, but now he was very annoyed after being reprimanded by Vice President Liu, not only Gao Feng, but also Pan Xianyi.

Others also expressed their opinions one after another. Most of them were opposed, but some were very positive.

Fu Jianyuan is one of them. He has been in the school for 9 years, but he has not achieved any major achievements. If he wants a subject, he has no subject, and if he wants an article, he has no article. If he continues like this, he will probably be a lecturer when he retires.This time he heard that the school was going to participate in the development of original research drugs, and he thought it was an opportunity.

Moreover, he has always been dissatisfied with the lifeless environment of the School of Pharmacy. The dean, Dang Ruxiu, has done nothing but care about his own three-acre land.The vice president, Lu Zhongwei, was ambitious, but he was obviously not very capable, so he tried his best to suppress the people below.

Fu Jianyuan has no subject and no articles has a lot to do with the other party.

"Kulu and the Party from the School of Pharmacy have been together for a long time!" He drank a glass of white wine, and dared to say anything at the moment, "My old man is willing to be the first bird, let's report the situation to Vice President Liu together."

There are several people at the table, all of whom are somewhat talented but depressed. At this moment, after a few glasses of wine, everyone's emotions burst out, "Go together! Go together!"

Vice-principal Lu Zhongwei soon learned of the news, and he was furious, "A bunch of scumbags have turned against you!"

But for a while, he really didn't have a particularly good way. There were many ways to suppress people, but Fu Jianyuan and the others were already at the bottom of the academy.

How to say that sentence: As long as I lie down, you can't knock me down.Fu Jianyuan is lying down now. He goes to two classes every day, and then waits in the office for get off work.

For such a person, Lu Zhongwei also made a difficult case, and he has no right to expel the other party.

Hard things are not enough, Lu Zhongwei decided to be soft, but Fu Jianyuan didn't like him at all, and dismissed the scientific research support fund he proposed.

Really think I am a fool, Fu Jianyuan thought to himself, if you draw a big pie for me at this time, if I believe it, I will be a fool.

Dang Ruxiu, the dean of the School of Pharmacy, didn't do much. This person is a tortoise, good at responding to all changes with the same and staying still.He himself has some achievements, as long as he doesn't make mistakes, others can't do anything to him.

Vice-principal Liu reported the situation to Principal Shen, who didn't know much about drug research and development, "Let's set up a school committee and let's discuss it quickly."

It's over!Vice-principal Liu thought that there must be opposing opinions on the school committee.Once the school decides to participate in this project, it will definitely have to invest a lot of money. Where the money comes from, it must be from the scientific research funds of various departments.

Now that even the School of Pharmacy doesn't care about this, other departments won't be happy about it. Who would think that the funds they get are too much.

Sure enough, most of the leaders expressed their objections, and finally it was Principal Shen's turn to express their opinions, and many people were ready to leave.

"I think the school should participate in this project." Principal Shen said, everyone was a little dumbfounded, didn't it mean that the principal didn't like it?
"This Gao Feng is quite talented. I asked a friend in the industry and he spoke highly of him."

"Moreover, this project must be led by the other party. They dare to invest money in it, which shows that they have great confidence."

"It's not too aggressive for us to get involved. The school's pharmacy school ranks very low in the country. It's not an option to lie flat. Something has to be done."

"President Dang, what do you think?"

"Ah, that's right!" Dang Ruxiu hurriedly said, "I have to do something."

Others also hurriedly echoed it, and Tong Juncai from the Department of Computer Science said, "It's still the principal who is far-sighted, and I actually agreed with it in my heart just now."

You agree with your uncle's head, you were the one who yelled the loudest just now, Dang Ruxiu scolded in his heart.

The resolution on participating in the research and development of Fengxin Technology's drug was passed unanimously, which deeply reflects the democratic nature of the school's decision.

Vice President Liu assigned Professor Pan Xianyi to take full responsibility for this matter, which aroused the dissatisfaction of Dang Ruxiu and Lu Zhongwei, especially the latter, who had a fierce confrontation.However, Vice President Liu didn't take him seriously at all. The two sides were not at the same level. He just expressed his dissatisfaction slightly, and soon someone told Lu Zhongwei to shut up.

"Original medicine?" Qi Huiren opened his mouth wide, and Dai Yonghui was also dumbfounded.

"Yes, why do you have such expressions." Gao Feng was a little speechless.

You are trying to die!Qi Huiren thought to himself, did you start the original research medicine?We, Xinhua Pharmaceutical, are still cautious, you are completely an old birthday star hanged yourself-you think you have a long life!

"Gao Feng, don't dare!" Dai Yonghui was in a hurry, "Do you know how much the original research drug will cost? Billions are possible! Do you have that kind of family background? And if it fails, all the money will be wasted. "

"I see that you have had a good life for a few days, and you don't know what your last name is."

Gao Feng couldn't laugh or cry when he heard what he said, but he also knew that Dai Yonghui was doing it for his own good, but how could they know that he was a cheating man.

"I'm sure, really, Lao Qi, you trust me."

"Hehe, I believe it." Qi Huiren laughed, "I have to report to the boss, I have no right to decide." He pulled Dai Yonghui and ran away without eating.

It's crazy, President Jiang of Xinhua Pharmaceutical thought to himself, but he was still a little curious in his heart, where did this Gao Feng come from so confident?

Being able to develop naturally, to synthesize catalytic substrates, and to make the first imitation of bevacizumab injection, the ability of the other party cannot be questioned by others.Thinking of this, Jiang Liangqian called Qi Huiren again, "Don't come back, and ask in detail later, I don't believe that Gao Feng is really arrogant."

Sometimes the idea of ​​a genius is incomprehensible to ordinary people. Jiang Liangqian does not think he is an ordinary person, but he admits that Gao Feng is a genius.

Soon, Qi Huiren learned the news that President Z would be involved, which surprised him and quickly reported to Jiang Liangqian. The latter was silent for a long time, and finally made a decision.

Qi Huiren, who returned to the company, introduced the detailed situation to everyone at the company's shareholders' meeting. Many people expressed concern about this, but none of them had the right to make a decision.

"Since everyone agrees, then this matter is decided." Jiang Zongxin took a sip of water happily.

Obviously disagree, okay?Vice President Liu in the audience almost gritted his teeth.

Z University welcomes Xinhua Pharmaceutical’s participation. In this way, the risk is further reduced. The three parties quickly signed a cooperation letter of intent, agreeing that the investment ratio is 2:1:1, and the future income distribution is 6:2: 2.

Regarding the recruitment of personnel, Z University has given great support. They have uniformly sent SMS recruitment messages from Fengxin Technology to undergraduates, graduate students, and doctoral students who have graduated in the past three years. This is the first time this has happened.

Yi Zhonglun is a graduate student who graduated last year. He is now working in a small pharmaceutical company along the coast. He came to the unit at [-] o'clock in the morning with a disgruntled face.

"Why do you come to work all day like you haven't woken up?" The boss was a little dissatisfied.

"I'll be late if I wake up and come to work?" Yi Zhonglun is not polite at all, 7000 yuan a month, the boss does not deserve his respect.

When he first went to work, because he was young and ignorant, he listened to the promise of his boss. At that time, he worked hard to work overtime.In order to allow the boss to live the life he wanted, Yi Zhonglun went out to work without saying a word in the tens of degrees of weather.

Open your eyes, work until the lights are turned off, and you can still breathe. The future is promising!

But half a year later, he discovered the cruel fact. It turned out that the boss was painting cakes, which greatly hurt Xiao Yi's feelings. He was already planning to run away with a bucket next month.

"Why did you leave at the o'clock? Have you finished your work?" The boss was very angry.

"I can't finish the job you assigned even if I work overtime all night." Yi Zhonglun said speechlessly, "Let's do it tomorrow."

"Didn't you say that you have the ability to withstand pressure when you recruit?" the boss muttered.

I do have some ability to withstand stress, but I didn't say that I would die at work!Yi Zhonglun put on his bag and left without looking back.

After eating and returning home, he lay on the bed and took out his mobile phone. Everyone in the classmate group was chatting about the recruitment of Fengxin Technology, which aroused everyone's enthusiasm.80% of the students studying at Z University are from the province. If they can stay in the province to work, most of them may not choose to go to other places. The people here have a kind of love for family in their bones.

It's a pity that the salary in the province is too low. If you get a salary of 1 in the coastal area, it would be good to pay 5000 when you come back here. Some even have to discount it, so the brain drain is severe.

"Is anyone working there? Is the salary real?" Most people expressed doubts. According to the recruitment information, it is no worse than Beijing, Shanghai, Guangzhou and Shenzhen.

Soon someone replied to the above question, "It's true, we have several juniors in there, and the boss is like an idiot, sending out money like crazy."

"They made the first copy of bevacizumab injection. I heard that Qihui Pharmaceutical is doing clinical trials. Once successful, it will be 2 million a year."

Yi Zhonglun was moved when he saw the news in the group. He is unaccompanied here, and he can run away at any time. The benefits of being single are suddenly revealed.According to the local recruitment mailbox on the information, he quickly turned on the computer and sent a resume to it.

There are many people who are unsatisfactory like him. After all, there are so many graduates every year, Z University is just an ordinary 211 college, and it has no advantage in the domestic competition.

"As long as they graduate within three years, all of them are allowed to come for trial work, without interviews." Hu Jiaran discussed with Zhao Xingye, this time the company must recruit at least 3 people, so as to build a basic framework.Xinhua Pharmaceutical will also send a team of about 100 people, with an old acquaintance Dai Yonghui in charge.

Although Z University is very powerful, there are not many people who send their resumes to Fengxin Technology's human resources mailbox. As long as the work is good, most people don't want to make changes. Who wants to leave an environment they are already familiar with.

(End of this chapter)