This doctor has a system

Chapter 228 216. Then prove it to me

"How long will it take to wait?" my sister asked.

"One year at most. If it doesn't work, then let's not wait. When the time comes, whether it's surgical repair or interventional closure, just do it for the child." Vice President Guo said.

Even if the product can be released in one month, it will still have to be tested on animals first, and it will definitely not be used directly on humans.

After discussing with his wife, Li Yifeng finally decided to follow Vice President Guo's advice. As a parent, you must want to do the best for your children, especially when you have a little money in your pocket.

"Gao Feng, my nephew's affairs are all up to you." Vice President Guo patted his shoulder and said, "Hurry up and come up with a charter. If you need me to come forward, please speak up at any time."

He now regards Gao Feng as one of his own, and some of his words are more casual.

"Don't worry, I will start working on this project this afternoon." Gao Feng responded. He had a good impression of Vice President Guo. Although he was a bit bureaucratic at times, he was very fair in general and handled some difficult matters. Very organized.

"Is this fully degradable occluder of yours reliable?" After receiving the news, Director Shen hurried over, "I'm confused!"

"I know you are talented, but one month is too short. You are setting yourself on fire!"

The occluder is not a simple medical consumable. It is inserted into the patient's heart. Currently, the terminal price of an ordinary metal occluder on the market is 2 yuan.

Is it possible to make consumables worth up to 2 yuan in one month?
You're thinking about ass!
But the person who said this was Gao Feng, and Director Shen was very entangled in her heart. She was afraid that the latter would get away with it. Although there were no serious consequences, there would always be some side effects.

"Don't worry, director!" Gao Feng said with a smile, "I'm really sure."

"You believe me!"

"I believe you, but we can't spare any manpower at the moment." Li Youliang said awkwardly, "The people over in Jiaran work overtime every day. Sometimes I worry that someone will die suddenly."

"It's easy to break the egg if you move too fast." Zhao Xingye quickly expressed his opinion, "The future of our original research drug is still unclear. It is not appropriate to launch a new project at this time."

"Opening a company is the same as fighting a war. The most taboo is fighting on both sides. Look at Germany during World War II."

"Besides, it's very hard for Hu Jiaran over there. If you add more burdens to him, he probably won't be able to bear it." He said a lot.

"What Lao Zhao said makes sense." Gao Feng touched his chin.

Hey, I listened to the advice this time. It seems that the boss is growing. Zhao Xingye is very happy.

"No, I'll do it myself this time. Youliang, help me. We'll get three more people, that's almost it." Gao Feng made the decision, "Tomorrow you and I will go to Z University to find Vice President Liu, and we'll ask him for someone."

"Why don't you look unhappy?" Zhao Xingye's wife asked with concern.

"The company is almost going bankrupt! How can I be happy?"

"Why is the company so bad every day?" His wife couldn't help laughing when she heard what he said, "Is the boss angry? Or is it the same Hu Jiaran?"

"Boss, he has another fantastic idea. This time he wants to make high-quality medical consumables." Zhao Xingye was confused. "The company is probably going to spend real money on it again."

"A lot of money has been spent on the original drug, but it hasn't seen any sound yet, and now it's going to do something else. I think the company will be ruined sooner or later."

"Don't worry. If the boss is willing to do the work, just let him do it. I think your company's financial operations are quite healthy. You can't spend all the money on the books."

After speaking, his wife thoughtfully handed him a cup of tea, which was full of wolfberry.

"what is this?"

"Wolfberry water."

"Where's the water? I think it's all wolfberry, not much water at all." Zhao Xingye said with a frown.

"You are not short of water," said the wife.

"I won't drink. I'm too tired today. Let's go to bed early."

"Do you want to die!"

"I'm telling you, Zhao Xingye, you must pay the public rations when you return home, otherwise I will think that you are supporting the third world outside!"

"I'm tired today, forget it." Zhao Xingye wanted to lie down after saying that.

"No! How long has it been since you touched me? I make you drink wolfberry water every day, and I keep giving you supplements. Today I have to check to see what kind of supplements you have."

"Get up quickly. Are you thinking about those female employees in your company right now?"

Zhao Xingye sighed, he was too lazy to speak out.

"Look, did I tell you the truth?" His wife pinched him, "You just have something in your heart!"

"Really not." Zhao Xingye said.

"Then prove it to me."

"How do you want me to prove it?" Zhao Xingye said speechlessly.

"How do you prove it?" His wife grabbed Xiao Zhao Xingye.

"No, just look through my phone." Zhao Xingye made his final resistance.

"Let me see what's the use of that!" His wife gave him a hard push, "Come here!"you
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"Experts on polylactic acid research?"

"Yes, we need to synthesize a new type of material."

"I have to ask Lao Dai, the chemistry major, about this." Vice Principal Liu of Z University thought for a moment, "Wait a minute, I'll call him now."

"Polylactic acid?" Professor Dai Rongcai, majoring in chemistry, was stunned for a moment. "Professor An Shangwu from our department has been working on this for a while, but he recently went abroad for exchange and only came back half a year later."

Half a year is too long. How could Gao Feng wait for so long?

"Has anyone else done this?"

"It doesn't seem to be the case, but Professor An's doctoral student is still in the workplace, and he should have been involved in this matter at the time." Dai Rongcai said, "But this kid's abilities are average. He looks stupid all day long and doesn't look very smart."

"Is that okay?" Vice Principal Liu looked at Gao Feng.

It's better than nothing, Gao Feng nodded.

"I don't want to go." Mu Zhentao said.

"Why?" Professor Dai Rongcai was very surprised. "They pay you a salary and don't let you work in vain."

"That won't work either. I haven't finished my graduation thesis yet."

"Where did you write the paper?" Li Youliang asked.

"Just started." Mu Zhentao was a little embarrassed. He had no sense of direction at all.

Then what are you writing about? Li Youliang was speechless.

"We will only delay you for a month, and I think you are not short of this amount of time."

"That won't work either. Professor An still has a project for me to look at. It will definitely stagnate as soon as I leave."

"And I have a paper to prepare."

Why doesn't this kid get enough oil and salt?Gao Feng was ready to give up. At worst, he would do everything himself. "Mu Zhentao, can you graduate this year after finishing your thesis?" Li Youliang asked.

"I guess not." Mu Zhentao hesitated. Doctors rarely graduate normally.

"Then why are you anxious?"

"Let me ask you again, is it easier for a doctor to graduate if he does better under his supervisor?"

"Of course!" Mu Zhentao blurted out.

"Think about it carefully." Li Youliang said, "I'll give you 2 minutes to think about it."

what does it mean?Mu Zhentao was confused.

Professor Dai Rongcai on the side shook his head at Vice President Liu, "Look, I have already said that this guy is stupid and doesn't look very smart."

"Are you stupid? The better you do, the more your instructor will rely on you?" Li Youliang.

"Yes." Mu Zhentao
"Then let me ask you, can Professor An's current project be completed this year?"

"Probably not."

"Then do you think he will let you go before the project is completed?" Li Youliang said, "If it were you, would you change a person in charge of a half-finished project? Especially if the person in charge does a good job. very nice."

"will not."

"Then what will you do?"

"Let the original person in charge continue to work." After Mu Zhentao said this, he was stunned. He suddenly remembered the senior brother who had been delayed for two years and the senior sister who had been delayed for one year.

"You work hard with Professor Gao for a month. I will talk to Professor An later and ask you to graduate this year." Vice President Liu said.

"Who are you?" Mu Zhentao asked.

"This is our President Liu." Professor Dai Rongcai sighed.

"Isn't our principal Academician Shen?"

"I'm the deputy!" Vice Principal Liu was about to cry because of his stupidity, "What have you been doing all day? Didn't I just hold a meeting for your chemistry major last week?"

"I usually don't go to meetings like this. It's meaningless and a waste of time." Mu Zhentao said.

"Let him graduate this year!" Vice Principal Liu broke the defense, "I really don't want to see him again."

"Calm down, calm down." Professor Dai consoled him, "You know, some students are stupid in school, but such people are often down-to-earth."

Hu Jiaran transferred Xu Bing and Yi Zhonglun over.

"Aren't you the team leader?" Gao Feng looked at Yi Zhonglun.

"Now I have been ignored." Yi Zhonglun said with a smile, "Dr. Gong's ability can kill me instantly. He has the final say in our group now."

Since Gong Fanshun arrived, the progress of group 3 has been far ahead of the other groups, so Hu Jiaran let the two of them come over.

"Okay, now our team is complete." Gao Feng announced the official start of the fully degradable occluder project.

The workplace is in the laboratory of Professor An Shangwu of the Department of Chemistry, whose project has been stopped by Mu Zhentao.

"It's not very important anyway. It won't have any impact if we do it after one month." Mu Zhentao said.

Professor An, who is far away in another country, would never have thought that his home would be lost during an exchange trip abroad.

"Our project is very simple. We must first synthesize polylactic acid." Gao Feng explained the process to everyone, "Mu Zhentao has some experience in this area."

"But unlike the rough synthesis steps in the Department of Chemistry, this synthesis is to be implanted into the patient's heart after processing, so some properties are very important."

"It must be completely degraded, and the degradation rate cannot be too fast or too slow."

Mu Zhentao on the side had a look of embarrassment on his face. This was probably too high a request.

If it was to be implanted into the patient's body, then the research he had done with Professor An before would be completely meaningless. What they were doing was for industrial purposes, which was very different from the requirements for medical consumables.

"First lead everyone to follow this." Gao Feng took out a preparation process.

Mu Zhentao quickly took it and took a look. It was a detailed experimental method for preparing high-purity polylactic acid. With this, the following was simply child's play for him.

"It's almost three days." He was very confident.

Gao Feng continued with other subsequent preparation processes in the system space. In fact, polylactic acid, as a material that is degradable in the human body, was discovered very early and has been approved by the FDA for use in surgical sutures and sutures since the 1980s. Intravascular stents.

The ventricular septal occluders currently on the market are made of nickel-titanium alloy. However, metal residues permanently left in the heart may lead to serious complications such as nickel metal allergy, myocardial wear, valve damage, conduction block, and thromboembolism. Overall The incidence rate is as high as 0.1%~8.6%.

It is mainly attributed to factors such as long-term release of nickel ions from the metal occluder, continuous compression of surrounding cardiac tissue, unrelieved inflammatory response, and delayed endothelialization process.

At this time, many people have placed their hopes on degradable materials such as polylactic acid and polydioxanone. Unfortunately, this concept has been proposed for a long time, but there is not much exciting news for the medical community.

"First, polylactic acid monofilaments are made by melt spinning. PDO particles with a molecular weight of 190 kDa are heated to 180°C. After melting, they are extruded from the spinning machine and cooled in a water bath to form 0.15 mm in diameter. Monofilament.

Weave a length of monofilament into a mesh tube and place it into the designed mold, heat to 120°C for 60 minutes, and cool to room temperature to form a double disk shape.

Two pieces of PLLA melt-spun occlusion membranes with a thickness of 0.1 mm were then laser-cut to matching sizes and fixed to the disc and the waist of the occlusion device with polylactic acid monofilament. "

This step seems simple, but it took Gao Feng three full days. The monofilament formed after the water bath is very thin and not very stable, so it is very difficult to weave it by hand.

Gao Feng was a bit handicapped, and he was so excited that he was stuck at this step. However, if the finished product is really produced, he will definitely use a machine to achieve this step in the later stage.

"Come on, Professor Ivor Glenn is very interested in you." Director Xin Guoyu of the Department of Cardiology called him.

"Who?"

"Ivor Glen!"

"I don't know." Gao Feng said.

"Then you must know his teacher, Reuven Jackson."

"It sounds a bit familiar, but I don't know." Gao Feng felt a little embarrassed for no reason. "I don't know much about foreign experts."

Why don't you even know about him?Xin Guoyu was speechless.

“Transcatheter aortic valve replacement was invented.”

"Oh, I wonder why it sounds so familiar!" Gao Feng suddenly thought about it.

"Then come quickly, Professor Ivor Glenn is waiting for you."

"I'm busy here." Gao Feng was reluctant to go over, "Isn't this a big shot in your cardiology department? What is my doctor from the respiratory department doing here?"

I'm not a professional, so I'm afraid there is no common topic.

"Professor Ivor came here specially to see you after your transcatheter aortic valve replacement. The main reason for him to see you this time is to see you." Xin Guoyu said to him anxiously, "We don't want foreign friends to come here. It’s easy, just do your best and come and meet me.”

high wind
(End of this chapter)