This doctor has a system

Chapter 433 498. Then don’t do minimally invasive surgery

As the saying goes: Thirty is like a wolf, forty is like a tiger, and fifty can absorb dirt while sitting on the ground.

But in fact, everyone has a misunderstanding of this sentence. The correct interpretation should be: 30-year-old people should have wolf nature and should not pursue comfort. They should be as greedy and energetic as wolves, working hard to achieve their life goals.

A 40-year-old person who has a successful career and a happy family cannot run around like a wolf without scruples, because the responsibilities on his shoulders need to reveal the majesty and wisdom of a tiger.

By the age of 50, you have experienced everything you should experience, good or bad, and have a clear understanding of yourself and your surrounding environment.

And I realize more and more that some things are destined to be unbreakable. No matter how powerful a person is, he cannot compete with the established destiny.

It’s time to be as thick as soil and become low-key and tolerant.

But Zhao Xingye’s wife is not included in this list. She is simply anxious and wants to drain her husband.
"I haven't seen you for such a long time. I don't think you're attached to me." Gao Feng said to Li Xinyao, "I'm completely focused on your son."

"I can't stick to you in broad daylight." Li Xinyao rolled her eyes at him.

Gao Feng found that his son had gained a lot of weight and his hair had grown longer. His eyebrows and eyes looked a bit like his wife's, and his mouth looked a lot like his own.

"It would be great if the country could increase investment," Gao Feng said. "Our investment in medical expenditure is too low, ranking in the middle and lower range globally."

"Why are these ears so big?"

After talking for a while and understanding the leader's intentions, Gao Feng chose to resign.

"What's the matter?" Gao Feng asked, "Why didn't you call?"

"I was talking about looking for you." Gao Feng replied, "Let's have dinner together tonight, and I'll report to you on my recent work."

As soon as he walked to the department, he saw an acquaintance, Director Shi of the Department of Pediatrics, sitting on a stool chatting with someone.

Director Shi wanted to make a call, but when someone said that Gao Feng had gone to Dean Guo, he decided to go directly to the general practice and wait for a while.

"It should be possible in the near future." Gao Feng replied. He had asked Zhao Xingye when he came here. The clinical trial of the degradable occluder was going very smoothly, and Pule Medical had already been gearing up to start a big fight.

Director Shi stood up immediately when he saw Gao Feng coming back.

But for hospitals, it is not worth celebrating. Public hospitals in China are rather strange. Although they have the word "public" in their names, they have long lost their public attributes.

"Yes." Dean Guo sighed, "It is a good thing for the people."

"Gao Feng, you're back." Director Shen happened to run into him when he was out of the clinic, "Why didn't you tell me in advance?"

"I don't dare to give you 100% guarantee on this, but there are no problems in animal experiments and human experiments."

"Boss, why have you lost so much weight recently?" Gao Feng asked casually after taking the tea from Dean Guo, "There are wrinkles on your face."

"Ask when you can do it." Director Shen called Dean Guo directly, and the latter asked Gao Feng to come to his office to find him.

In addition to a small amount of government funding every year, 80-90% of the expenses must be borne by the hospital itself, which is almost the same as self-financing.

"When can my nephew's ventricular septal defect be repaired?" he asked.

"If you are willing to be a guinea pig, I will arrange it for him next week."

"It's all our own stuff, don't dislike it." Gao Feng was a little tired, "Let's clean it up tomorrow."

"Then let's do it, the kids are really anxious." Dean Guo made the decision, "By the way, people have to publicize it well after it's done. This is a high-end thing."

"You can't do that." Director Shen said with a smile, "Dean Guo has been talking about you. Do you remember what happened to his nephew?"

"I have a very complicated patient."

Less than two days after birth, Mengmeng developed symptoms of suspected infection, including fever, diarrhea, and crying. I was treated in a local hospital for a period of time, but my condition did not improve significantly. Instead, it tended to get worse.

"No, but I feel that the child's immunity is defective." Director Shi said.

"It's sad." Dean Guo felt tired when he mentioned this. "Do you know that the prices of many medical services and examinations will be reduced?"

Gao Feng curled his lips and said nothing. His grandfather died of liver cancer in his 40s.
At night, Gao Feng let himself go completely, giving the opponent enough buffer time to stand by with his gun.

"Oh, the one with ventricular septal defect!" Gao Feng immediately thought of it.

"Immunodeficiency?"

"Then adjust it." Gao Feng said, "This is a good thing. The burden on the people will be lighter."

"When the child was born, he weighed 5 and a half pounds. Now he only weighs 4 pounds."

"When prices drop, employees' benefits will definitely drop as well." Dean Guo said helplessly, "Everyone has a hard time. But there's nothing we can do about it, hey."

He simply called the people from the Publicity Department over and asked them to get ready.

"Zhaofeng ears, this is a symbol of good fortune." Gao Ma said, "Your grandfather is like this."

"There are too many people." Dean Guo said, but there must be some other reasons.

"I'm looking for you," he said.

Li Xinyao was a little unhappy, but she didn't have any strength in her body, so she simply lay there and fell asleep. In the middle of the night, she was in a daze when the baby was brought over to feed her.

The patient, Mengmeng, was the child of Director Shi's relative. He was just over a month old and a boy.

"Is it safe?" Dean Guo asked again worriedly.

"The sheets are all there," Li Xinyao frowned, "Let's change them."

"The first move: the gun shoots out like a dragon." Before he could finish his words, his mouth was blocked by soft jade lips.

"Have any problems been found?" Gao Feng asked as he walked.

"Correct."

Because there were times when Mengmeng got better, but within a few days after arriving home, he would catch a cold and become infected, and had to be hospitalized again.

Gao Feng soon saw the little patient, who looked wrinkled and already asleep.

The child's mother was very haggard, her eyes were red, and she must have been crying a lot.

"It's a lot of pressure. She had given birth to a child before and it died within half a year." Director Shi said softly to Gao Feng.

After carefully looking at the test results, Gao Feng frowned. The child had lung and gastrointestinal infections, with obvious symptoms of diarrhea, and stool culture showed Salmonella.

There are also Candida infections of the skin and mucous membranes, and this is despite the use of broad-spectrum antibiotics.

"Something's wrong." "I feel something is wrong too. This child's immune system seems to be not working." Director Shi said.

"Have T cell and B cell function been checked?"

"I checked, but the results haven't come out yet," Director Shi replied.

"You just said that the patient's mother had a child before, and it died in infancy?" Gao Feng asked.

"Yes, that's a boy too." Director Shi didn't ask much about this, for fear of irritating the patient's mother.

"Well, it disappeared in about half a year." The patient's father obviously didn't want to mention this.

"Has that child ever had such a similar situation?" Gao Feng asked.

"Yes, it is easy to get sick." The patient's father was a little panicked when he mentioned this, "Director, my child has no big problem, right?"

Gao Feng didn't answer, he already had a clue in his mind.

With the authorization of the patient's father, Director Shi made several phone calls and soon learned about the condition of the deceased child.

Similar to this child, he also suffered from recurring lung infections and intestinal infections, and eventually...
"It should be severe combined immunodeficiency disease." Gao Feng said.

Severe combined immunodeficiency disease is a disease of humoral and cellular immunity deficiency. This disease is due to the congenital abnormal differentiation of lymphoid stem cells, and the infant lacks T cells and B cells after birth, resulting in defects in both humoral and cellular immunity. It is a severe form of combined immunodeficiency disease.

Due to the combined defects of humoral and cellular immunity, children are susceptible to various pathogenic organisms. Clinically, children often suffer from recurrent pulmonary infections, oral candida infections, chronic diarrhea, sepsis, etc.

"Our hospital seems to have diagnosed a case before." Director Shi thought about it for a while, but the patient later went to the capital, and there was no news after that.

"It is best to do both in vivo and in vitro B cell and T cell function tests." Gao Feng suggested, "If there is obvious inhibition, then we are almost inseparable."

"Yeah." Director Shi nodded, "Then what's the next step of treatment?" he asked.

Gao Feng looked at him and said nothing.

Severe combined immunodeficiency disease is also called "bubble disease". Because children need to be placed in a sterile warehouse for a long time, it is like being in a big bubble.

Most children with "bubble disease" usually develop symptoms around one month after birth. They lack resistance to infections such as bacteria, fungi, viruses and mycobacteria, and suffer from repeated and severe fatal infections. Most children have no chance. He received timely diagnosis and stem cell transplantation treatment, but died within 1 year of age.

Even if you can barely survive, the quality of life will be severely reduced due to repeated interstitial lung disease, prolonged ejaculation, and developmental arrest.

There is a foreign movie specifically about this disease called "Bubble Boy". The protagonist is a severe combined immunodeficiency disease patient named Jimmy. Jimmy, who lives in a bubble, cannot go out to play, invite friends to his home, go to school, or do what he wants to do like his peers. His life has become simple and boring, so boring that he is going to get moldy.

If Jimmy wanted to go out, he would have to wear a bubble suit with long isolation gloves...

In fact, the movie has downplayed the horror of the disease. The movie is based on a child (David Witt) who was born in 1971 with severe combined immunodeficiency disease. It is reported that he was admitted to the hospital less than half a minute after he was born. in a sterile isolation bubble.

Since then, he has spent most of his life in the bubble. Every item that enters the bubble needs to be disinfected and ventilated for 1-7 days before entering the bubble.

NASA's space agency specially made a spacesuit for him, allowing him to leave the bubble for a short time and move freely outdoors.

In 1983, David Witt received bone marrow from his sister. The bone marrow transplant went smoothly, but the dormant virus in his sister's bone marrow caused David to suffer from lymphoma. Eventually, his life stopped at the age of 12.
"I'm afraid that the child's mother won't be able to accept it." Director Shi sighed. He had long been aware of the difficulty of the patient's condition. When he saw the child for the first time, he had a premonition that the child would not survive.

"There should be something wrong with the parents' genes." Gao Feng thought for a while and said, "It's most likely the mother."

"If they still plan to have children in the future, it is best to undergo targeted genetic screening."

Director Shi went to talk, and the couple finally adopted Gao Feng's suggestion.

The results were nothing left to chance, with the patient showing significant suppression in both in vivo and in vitro B-cell and T-cell function assays.

After genetic testing, it was found that the disease-causing gene of the child was indeed inherited from the mother. She carried a heterozygous mutation of the IL2RG gene on the Normal, girls are half normal and half carriers.

"They are also quite unlucky." Li Youliang on the side couldn't bear it. There was half a chance, but both times it was the worst outcome.

"Three generations of test-tube babies can be made." Director Liu from the Reproductive Department was specially invited by Director Shi to help the parents of the children build confidence in their future lives.

"You can take multiple valid blastocysts first, and then screen out the ones that don't carry the disease-causing genes. You can definitely give birth to a healthy baby!"

After one month of treatment, the child's condition improved significantly, but everyone had heavy expressions on their faces when they were discharged.

Three months later, the boy named Mengmeng left. He did not stay in this world as long as his brother.

When Gao Feng learned the news, he was in a bad mood, but this is the limitation of medicine.

Even if the causes of many diseases are understood, effective treatments cannot be found. In the end, patients can only watch helplessly as they die step by step.
-
Father Li has been having blood in his stool recently. He had hemorrhoids before, but this still attracted the attention of the whole family.

Gao Feng specially brought him to the anorectal clinic today for a checkup.

"Your problem is not serious, but you need to change some living habits." Director Ma of the Anorectal Department was discussing the condition with a patient.

"Then I'll go back and take medicine?"

"Medicine won't work, and a minor operation is needed." Director Ma said, "We have to cut off this piece and then sew it up."

"This." The patient hesitated, "Doesn't it hurt?"

"It doesn't hurt, and it feels very comfortable when I do it." Director Ma said, "It feels so good."

"Really?" The patient didn't believe it, "Are you kidding me?"

"You opened it first."

patient
"Are you a tomboy?"

"No." The patient was stunned, "What do you mean by asking this?"

"If not, then you can choose minimally invasive surgery." Director Ma's expression was serious, "If you are a man, then minimally invasive surgery is not allowed."

"Because it was minimally invasive, he had a circle of nails inside."

"That's why I'm asking this."

"Otherwise, if there is a ring of nails inside, it may affect you in the future."

"There are dozens of nails, and it's bonded to your flesh, which is unattainable."

"It's just that if you eat a potato raw, it will be shredded potatoes." The patient asked, "Is that true?"

"You can understand it this way." Director Ma didn't know how to evaluate this statement.

"Oh, forget it, don't do minimally invasive surgery." The patient said.

(End of this chapter)