This doctor has a system

Chapter 556 619. Three hundred million US dollars is indeed too...small?

"How is this possible?" Professor Norman was also very shocked. He had participated in the development of a drug before. Although it failed, he knew all the steps involved clearly.

Not to mention just a few words, even if the experimental records were shown to you, non-experienced participants probably wouldn’t be able to understand them.

How is it possible to infer any valuable information from just a few pictures and some text?
"Hey, I have some talent for this." Gao Feng said modestly, "Of course, there is also a certain element of luck."

At this time, Kojima Miyajima Reiro didn't know what to say. Compared with the person in front of him, their R&D department was full of losers.

"It is indeed necessary to optimize it." He thought to himself, Takeda Pharmaceutical is a pharmaceutical company with a sense of social responsibility. There is no reason for it to monopolize a large number of talents. It should learn from the experience of certain companies and regularly supply experienced practitioners to the society every year.

By the way, let’s send Shuichiro Masuyama out first.

"Mr. Gao, you are so talented!" Miyajima Reiro praised loudly, "Your talent has completely conquered me."

"Takeda Pharmaceutical strongly requests your cooperation!"

"Oh, I wonder how your company would like to cooperate?" Gao Feng asked with great interest.

"After all, Rexedinib has cost the company a lot of effort. Although giving up rashly like this won't have a big impact on us, it's still not good." Miyajima Reiro said after thinking it over. "Since Mr. Gao has a way to improve it, that's great."

This little island was just talking about investing tens of billions of dollars or something, but now it says that giving up will not have any big impact on the company.

In the final analysis, it's because I'm afraid of being ripped off by him.

But Gao Feng could understand it. It was human nature and anyone would do the same.

But can you run away? My sword is thirsty.

"Although the improvement is not difficult, it will cost a lot of money." Gao Feng kindly reminded, "Takeda Pharmaceutical is a big company, so I think it can afford it."

This sounded a bit bad. Kojima Miyajima Reiro was very nervous. It seemed that the Chinese were going to ask for too much.

"How about you name a price?"

Gao Feng glanced at him and slowly stretched out six fingers.

"Six hundred million US dollars? Oh my God! This is outrageous!" Miyajima Reiro screamed, "There is no way we can accept this price!"

Gao Feng was stunned for a moment. Actually, he wanted to say 60 million. Why not 50 million or 70 million? Because six is ​​a lucky number.

"Don't get excited, I mean"

"Six hundred million is absolutely not acceptable!" Miyajima Reiro interrupted the greedy Chinese rudely, "This price is too outrageous!"

"It's not that we can't talk about it." Gao Feng hesitated.

"I need to report to the company." Miyajima Reiro said and went to make a phone call. Even though he was the vice president, the upper limit of funds he could mobilize was only 1000 million US dollars. This greedy Chinese man asked for million right away, and he did not have this authority.

"If he can guarantee that the improved rexitinib can successfully pass clinical trials and has proven efficacy, then US$600 million is not unacceptable." Chairman Yudai Miyake is very courageous. The main reason is that the company has already invested tens of billions of dollars. If this project is cancelled, the loss will be devastating.

Now some people say that the problem can be solved, and we must grab this life-saving straw. If we think about it carefully, six hundred million does not seem expensive.

"Mr. Gao, this price is too shocking. The company cannot accept it." Miyajima Reiro's expression was very serious. "Both sides need to show sincerity."

"You are right." Gao Feng agreed, "I just said that it is not impossible to talk about it."

"Is three hundred million enough?" Miyajima Reiro asked tentatively, "You need to ensure the efficacy of the improved drug and that it can successfully pass clinical trials."

"How can you bargain like that?" Li Youliang interrupted, "Do you think you are buying pants in a wholesale market?"

"Yes! Three hundred million dollars is indeed too...small?" Professor Norman agreed and fell into deep thought. Oh my God, what is he talking about?
"You are not sincere, Mr. Miyajima." Gao Feng said seriously, "The process of improvement is very difficult and requires a lot of manpower and material resources!"

"You know how high the labor cost is now."

"Another thing is that I am also committed to PD-1 related research, which is related to the competition for the Nobel Prize next year."

"The improvement of the drug will take up a lot of my valuable time, and your company needs to compensate me."

"I promise you here that if the improved drug fails to pass clinical trials, I will not take a penny."

"What about the therapeutic effect?" Miyajima Reiro asked.

"The efficacy will definitely be much better than the current one." Gao Feng said with a smile, "But this cannot be written into the contract."

"why?"

"What do you think?" Gao Feng asked back. It is easy to argue about the efficacy of the medicine. He has worked hard to make the medicine, but someone says that the efficacy does not meet expectations. Who can he go to for justice?

Miyajima Reiro suddenly stopped talking.

“We can find a trusted third party.”

"No, there's no room for negotiation. I can only ensure that the drug passes clinical trials smoothly." Gao Feng's attitude was firm. He didn't trust these small islands. Huge profits would bring about waves of troubles, and he didn't want to waste that energy.

Miyajima Reiro went to make another phone call, and Li Youliang poured a glass of boiled water for Gao Feng and Professor Norman.

"How rude! Why don't you pour a cup for these friends from the island countries as well?" Gao Feng "blamed".

"Help up this friend named Xiu'er too. The ground is so cold, can your butt bear it?"

Takeda Pharmaceutical
Several company bosses are arguing with each other.

"The Chinese cannot be trusted. I think he has a conspiracy," said the opponent.

"I think we can give it a try. The other party said that if we can't complete it, they won't take a penny." Those who agree have more reasons, "The company has invested so much, and it doesn't need another 6 million yuan."

"Right! If it doesn't work, we won't have to spend 6 million!"

"Yes, I hope the Chinese are able to take the 6 million away."

"We can make the conditions for passing clinical trials more stringent," the executive director suggested, "to put some pressure on the Chinese."

"agree!"

"agree!"

Soon, Takeda Pharmaceutical dispatched a professional negotiation team, and Zhao Xingye in China also immediately took action.

I don't need to work hard at all. The boss's own income is enough to support everyone. Manager Zhao is very pleased and he only needs to take care of the family.

The negotiations went very smoothly. Gao Feng looked at the other party's demands and felt they were very reasonable.

"Don't you think the conditions are a bit harsh?" Professor Norman asked, "I see that they have added a lot of requirements in clinical trials compared to before." "It's okay, drugs developed in this way are also safer for patients." Gao Feng replied. He felt no pressure in his heart, because he had already worked out the improvement method and it was not very difficult.

Simply put, the active ingredient first goes through 16 procedures to replace the original methyl group with a hydroxyl group, and then goes through 8 chemical reactions to sulfurize the new ingredient. In this way, the final ingredient not only avoids side effects on the heart, but is also more stable and more effective than before.

These 24 steps were an impossible task for Takeda Pharmaceutical, but Gao Feng only spent 150 skill points.

There is no way, cheating feels good for a while, and it will be more fun if you keep cheating.

"According to the contract, we will advance half of the funds, 2.8 million US dollars." Miyajima Reiro was in a good mood at the moment, "Thank you for your hard work, Mr. Gao!"

"Yeah." Gao Feng nodded. The other party would send a small team to participate in the next improvement process. He did not refuse. It would be a waste to make good use of the free labor.

A month and a half passed quickly. During this time, Gao Feng accompanied Professor Norman and Jerry Gallagher of AstraZeneca to visit many scholars, who were able to influence the evaluation of the Nobel Prize in Medicine.

Most people welcomed his arrival, while some declined, but overall, the gains far exceeded expectations.

On this day, Gao Feng was chatting with Professor Norman when Professor Rutherford Monroe from the Castleman Disease Exchange Conference came over with a look of excitement on his face.

"Professor Gao! Davis' condition has improved significantly!"

“He survived!”

Davis is the Castleman patient with the big belly, spindly limbs, and swollen feet.

This middle-aged man originally came from a wealthy family and was considered middle class in Stockholm, but due to seeking medical treatment in recent years, he almost spent all his savings.

Davis had already prepared for his death and even wrote his will: "The last $50,000 will be donated to the federal government, and the cell phone will be left to my beloved wife."

"Is this a mistake?" Professor Rutherford Monroe, the attending physician, was very surprised. "Your broken phone doesn't look like it's worth even $100."

"But there is evidence of her cheating in it."

It turned out that Gao Feng's idea was completely correct, and sirolimus had a significant therapeutic effect on patients with Castleman disease.

Babbitt Harry and several other professors at Oregon Health and Science University were very surprised by the discovery, and they have already given the drug to their patients.

The next step is to study the pathogenesis of Castleman's disease in detail, which is bound to overturn existing theories and guidelines. Everyone is very excited because this is a major event that will go down in history.

"Professor Gao, you take the lead and we will follow you." Professor Rutherford Monroe said sincerely.

"No, this is far from my major, and I can't devote too much energy to it." Gao Feng declined. These professors used to do this for love, and now that Castleman disease has finally found a new direction, let them go ahead and do it.

Hopefully, they will eventually gain fame, fortune and honor.

The purpose of this exotic trip has been achieved, and Gao Feng can't wait to embark on the journey back home. The living environment in Sweden is better, but he still prefers the crowded and noisy State Z.

"Hello, are you Mr. Gao Feng?" the beautiful flight attendant asked.

"It's me. What's the matter?" Gao Feng replied.

"You and your companion can be upgraded to first class for free." The stewardess showed a charming smile on her face, "Please follow me."

The first-class cabin is very large and more comfortable to sit in, but seats are not easy to buy. When Li Youliang went to buy tickets, he was told that they were sold out. He didn't know why there were so many rich people.

"Didn't they say it was sold out?"

"We learned that you were on the plane, so we specially communicated with the two first-class passengers. They are very happy to give up their seats to you two."

"Thank you." Gao Feng.

As soon as the two of them sat down, a first-class passenger next to them stood up and insisted on shaking hands with Gao Feng.

"I know you! You know Kung Fu!"

"I feel completely safe now!" said another female passenger.

After the plane took off smoothly, the captain wearing a white hat opened the cockpit door and walked straight to Gao Feng.

"Mr. Gao Feng, come and take a look at our cockpit."

This is a Boeing 787, which looks much smaller than the Airbus A380, but the cockpit is more complicated, with many more mechanical buttons, and the degree of electronicization is obviously not as high as that of the A380.

"Do you want to try it?" the captain said enthusiastically. "It's much easier to fly than the Airbus A380."

"Forget it. I don't really want to fly a plane in my lifetime." Gao Feng smiled and shook his head. If there wasn't a system, he would have been picked up by his grandmother long ago.

But without the system, there might not have been a trip to Sweden.

Due to high winds, the cockpit door of the Boeing 787 was kept open throughout the flight, and the passengers had no objection to this.

After landing, Gao Feng couldn't wait to go home. When Li Xinyao saw him, she burst into tears.

"Don't take a plane anymore!" Gao Ma warned. "If something goes wrong with that thing, you won't be able to escape!"

"Yes, let's take the train. If things really don't work, we can always jump off the train." The mother-in-law agreed very much.

"It's okay." Gao Feng smiled and patted his wife's shoulder. "Actually, the situation wasn't that bad."

"Flying a plane is very simple, easier than getting a driver's license."

Fengxin Technology Laboratory

"Why are there so many little islands here?" Wang Liang was very puzzled. "They all look stupid."

"You are so rude! Chinese!" Zengshan Shuichiro was very unhappy.

"Holy crap! This guy can understand Chinese."

Masuyama Hideichiro

In order to show their importance to the project, Fengxin Technology and Takeda Laboratory specially held a ceremony, which attracted many people to participate.

First came the district leader, then the city leaders, and Vice President Liu from Z University also came to join in the fun.

"How can this be called joining in the fun?" The other party pulled his hand and shook it back and forth, "You are a professor at our Z University, so naturally our school will have a share of the fame and fortune you have gained!"

"You can't forget your roots!"

"This is Takeda Pharmaceutical's Vice President Reiji Miyajima and R&D Department's Hideichiro Masuyama." Gao Feng introduced several key leaders, "This time we are collaborating mainly on a drug called Rexitinib. Currently..."

(End of this chapter)