Gou is practicing medicine in the clinic

Chapter 530: Boiling bones, the principle of reanimating dead bones

"This is the child's examination report at the provincial hospital. They recommended that we perform amputation to prevent the tumor from spreading further."

The child's father handed the information packet to Li Jingsheng.

After taking it, Li Jingsheng looked at it carefully.

The child's tumors mainly occur in the middle of the radius.

No problem has been found with the ulna for the time being.

Judging from the performance of bone tumors, the degree of malignancy is very high, and it feels like it is in a period of rapid expansion.

Tumor cells and viruses share a common characteristic: they replicate themselves crazily and grow their own 'population'.

During the replication process, tumor cells not only consume a large amount of body nutrients, but also continuously occupy the living space of normal tissues and organs. It destroys the original normal tissues of the body.

It is somewhat similar to attacking a city and quickly occupying the territory of normal tissues or organs.

The vast majority of cancer patients die not from cancer but from complications.

For example, liver metastasis caused by lung cancer may eventually destroy liver function or damage lung function, leading to the death of the patient.

The tumor itself will only make the patient lose weight, the body will have an inflammatory-like reaction, and cancer pain will also occur.

"The child is still so young. What will her future life be like after amputation? Dr. Li, we heard that your orthopedic medical skills are very good and we came here because of your reputation. Please help us find a solution!"

The child's mother wiped her tears and choked in a choked voice.

Her eyes were pleading.

"Don't be anxious. This disease is difficult to cure and is extremely malignant. It is easy to relapse and metastasize. I will feel the child's bones first to see her specific condition."

Li Jingsheng looked at the little girl.

"Kid, do you know which way is on the left?"

"I know! This way!"

She raised her left hand, but immediately showed a pained expression.

"Awesome! You can tell the difference between left and right at such a young age. When I was as young as you, I often couldn't tell the difference between left and right. My kindergarten teacher told me to turn right, but I was the only one in the class who turned left."

"Haha...Uncle Doctor was so stupid when he was a kid."

Children are childish and say whatever comes to mind.

"Hey, no swearing."

The child's father was worried about making Li Jingsheng unhappy, so he quickly scolded the child.

"It's okay! It's easy to chat with children. They don't have all the worries of adults and have a childlike innocence that adults don't have."

Li Jingsheng smiled and waved his hands.

"Here, take off your left sleeve and expose your left arm."

With the help of her family members, the little girl retracted her left arm from her sleeve.

With the naked eye, you can see a mass on the forearm of your arm.

Li Jingsheng felt her bones and carefully checked for bone tumors.

His bone touching skills are now very good. After touching the bones, he can more accurately identify the health of each segment of the bone.

Bone cancer has a strong ability to infiltrate and even metastasize.

If metastasis has just occurred, it will be difficult to detect it with current medical examination methods unless a specimen is taken for biopsy.

But Li Jingsheng can make a diagnosis by touching the bones.

By repeatedly touching the bones, he basically determined that the little girl's bone tumor only occurred in the middle part of the radius for the time being.

They also carefully touched the bones of her left arm, shoulders, and even the leg bones of her back and legs, but no bone cancer was found either. This made Li Jingsheng secretly happy.

The child's bone cancer occurred in a superficial part. After being discovered by the parents in time, he was sent to the hospital for examination, which did not delay the condition.

This provides a good basic condition for the child's radical cure.

Amputation is the easiest and cleanest method.

But as her parents said, after the amputation, she will be disabled for life.

Li Jingsheng has been studying cancer treatment technology recently and has achieved some success.

It would be great if there was a way to treat this child that had the best of both worlds.

It can not only save the child's arm, but also completely kill the cancer cells.

"The child's condition is more serious. The bone tumor should be in a period of rapid expansion. If not treated in time, it can easily metastasize and spread to multiple parts of the body. If you come to me specifically, I will definitely do my best on this matter. If you are willing to wait a moment If you want to wait, please leave your contact number and I will go to the clinic later to do some research and try to come up with a treatment method that can save the child’s arm while also destroying the tumor cells.”

Li Jingsheng said to the two family members.

Diagnosis requires caution, and treatment requires even more caution.

In particular, the planning of surgery requires repeated consideration and deliberation.

There is a rule in playing chess, which is no regrets when you make a move.

Surgery eliminates disease at the expense of destroying the patient's body. It is easy to destroy and almost impossible to restore.

Therefore, a responsible doctor will think over and over again in his mind when formulating a surgical plan.

They may even find ways to ask other doctors for advice and start discussions together.

"We are willing to wait! Please Li Jingsheng to take more trouble!"

The child's father quietly took out a red envelope from his pocket and stuffed it under the table to Li Jingsheng like a thief.

"Don't be like this, don't be like this. I treat patients. This is my job and what I should do. It is very unfortunate that your children are sick, and the financial burden will be heavy. Keep this money for the treatment of your children. For me, as long as I can cure my child's disease, it is the most gratifying thing."

Li Jingsheng declined the red envelope from his family.

His words made his family members admire him even more.

……

After the noon consultation, Li Jingsheng was thinking about the child's treatment plan while eating.

Chemotherapy?

The effect of chemotherapy for bone cancer is not ideal, and the child's body may not be able to tolerate it, and the best opportunity for surgery may be missed, causing the cancer cells to spread.

Chemotherapy can indeed kill cancer cells, but it is by no means a panacea.

Not to mention that during chemotherapy, cancer cells will no longer spread and develop.

Without chemotherapy, the only option left is surgery.

There is currently no specific drug for bone cancer.

Technologies such as radiofrequency ablation are also useless.

Li Jingsheng frowned and thought hard.

Currently, there is low-temperature inactivation technology for treating tumors.

The lesions can be frozen to death to achieve the purpose of killing tumors.

There are also methods to eliminate tumor cells by cutting off the supply. Cut off all blood supply and other nutrient transport to the lesion, allowing the tumor to die without food.

This approach was also inappropriate for this child's bone cancer treatment.

While he was thinking hard, a bold idea flashed in his mind.

When he was learning bone cement treatment technology from Professor Wu, he looked up information and saw a brand new bone cancer treatment method. Although the current technology is still immature and there are still many problems that need to be solved, this treatment technology has its unique advantages.

Li Jingsheng immediately used his mobile phone to search for relevant literature.

It's a pity that because it is a relatively new technology, he did not find relevant literature.

There should be very few doctors doing research in this area.

Because when treating patients, doctors are only 'designers' and executors. It is the patients and their families who have the final say on what treatment plan to choose.

To put it bluntly, doctors and patients only have a cooperative relationship. After a patient enters the hospital, he or she is not treated as the doctor says.

If the patient has questions or concerns, he or she may disagree with the doctor's treatment.

"There are no practical cases for reference, and the patient is still so young, so the family members may not agree!"

After repeated thinking, Li Jingsheng felt that this new technology would be very suitable for treating this little girl's bone cancer.

Although many unknown problems may arise during the treatment process, he is confident that they can be solved.

The team has gradually developed into a medical collective including anesthesia, nutritional support, postoperative care, general surgery, orthopedic surgery, and auxiliary traditional Chinese medicine.

If the high-end medical business can continue to expand, his team can continue to recruit high-level talent.

The ultimate ideal is for the team to treat diseases from the nine major systems, the three major circulations, and the combination of traditional Chinese and Western medicine, and provide all-round support to the patient's body.

If the team really develops to that scale, there should be very few untreatable diseases in the world.

After Li Jingsheng finished his meal, he looked to see if there was still about half an hour left.

I won’t go to Ou Qinglan today.

He decided to have a good talk with his family members and try to get their support.

Call the child's father directly.

"Hello, is this Mr. He?"

"I am, what's the matter with you?"

Mr. He on the other end of the phone looked very wary.

"I am Dr. Li from the Orthopedic Surgery Clinic of the Second Hospital. Regarding your daughter's treatment plan, I now have a treatment plan that can save limbs and eliminate cancer. I want to talk to you in person."

"Oh, it's you! Okay, okay, I'll go find you right away."

After hearing this, Mr. He was so happy that he almost jumped three feet high.

You can feel his excitement through the phone.

This is really great news.

"I'll wait for you in the outpatient room of the hospital! Please be safe on the road."

Li Jingsheng warned and hung up the phone.

Less than five minutes later, Mr. He ran over sweating profusely.

"You came so quickly, are you near the hospital?"

"Yes, we found a small hotel to stay in. We were waiting for news from you. I didn't expect there would be news at noon."

Mr. He looked very excited.

"Sit! Let me tell you the treatment plan first. The treatment plan I set for the child is to remove the tumor through surgery, and then cut off the diseased radius segment. Boil it in high-temperature liquid to completely kill the bone. tumor cells. Then the bone is grafted back.

Because it is autologous bone regrafting, there is almost no need to worry about rejection.

And the cost is relatively low.

The child is still young and has strong growth function. If the operation is successful, the transplanted radial bone has a high probability of survival. This can perfectly solve bone cancer and save the child's left upper limb. "

Li Jingsheng gave a rough outline of the treatment plan.

After hearing this, Mr. He felt a little worried.

"After the bones are cooked, won't they die? If they are transplanted back, will they still be alive?"

"This depends on the recovery from the surgery. The bone may heal slowly, but there is a high probability of survival."

Li Jingsheng couldn't give a definite answer.

Seeing that the family members still had concerns, he had no choice but to educate them.

“After the cooked bone is transplanted back, whether it can heal with the host bone is mainly affected by factors such as its own osteogenic activity, osteoclastic bone resorption, osteoinduction, and osteoconduction.

Osteoblasts in transplanted bone have the ability to form new bone at an early stage.

Osteoclasts absorb bone minerals, and dead bone is gradually replaced with new bone.

The transplanted bone mainly serves as a scaffold and conductor. The surrounding soft tissue bed, capillaries, and osteoprogenitor cells will slowly grow from the host bone into the transplanted bone through the mechanical conduction of the bone graft.

Because the grafted bone has been cooked, we call it inactivated in medicine.

Its osteoblast and induction activities are basically lost.

Therefore, healing does not depend on it, but on the living bones at both ends of the transplanted bone. It mainly plays a conductive role.

When I replant the bone graft, I will try to restore its capillaries to unblocked first.

In this way, new bone can be slowly generated from the outside in to replace the dead bone. "

Li Jingsheng spent a lot of time explaining the treatment principles to the family members.

Mr. He half understood what he said, but the worry on his face was obviously relieved.

"Let's talk about other benefits of using inactivated bone for regrafting. Because the regrafted bone itself is cut from the middle of the original bone, it can naturally maintain the continuity and original shape of the bone after replanting. It has no immunity. Rejection and transplantation of allograft bone carry the risk of possible infectious disease.

In addition, inactivated bone cancer cells can be used as antigens to stimulate the child's immune system and enhance the body's immune function.

I personally think this is very important and can significantly reduce the chance of recurrence. "

Li Jingsheng continued to talk about the benefits of this treatment.

Having opened a clinic for so long, he has a good grasp of the psychology of family members.

Know what their biggest concerns are.

The total number of cells in the human body is about 50 billion. A large number of cells die every day, and then new cells are born.

During the birth of new cells, individual cells mutate.

It does not grow according to the original cell shape and function, but has mutations.

This is actually a cancer cell.

Even if the probability of developing cancer cells is one in ten million, cancer cells will often appear in our bodies.

But don't worry about getting cancer.

If cancer cells were produced in the body, cancer would occur, and the human race would probably be extinct long ago.

The immune system in our body will attack those mutated cells mercilessly and destroy them. This avoids the possibility of getting cancer.

But some cancer cells are particularly cunning and powerful among cancer cells.

It disguises itself as a normal human cell to evade the immune system.

It is more dangerous at this time, and the probability of getting cancer will increase significantly.

Some people like to smoke, drink hard, stay up late, and often do not exercise, which will increase the probability of cancer cells.

Moreover, after smoking for a long time, the probability of producing 'super cancer cells' will also increase significantly.

Also, the immune system has to help the body fight against a large number of viruses, bacteria, etc. every day, and its work is tiring enough.

If only one cancer cell appears among 10 million newly born normal cells, it can find this cancer cell in a timely and efficient manner and send troops to kill it.

But when there are ten or even a hundred cancer cells among the ten million newly born normal cells, the immune system will be extremely busy.

It can still hold up for one or two days.

This is the case every day, and the number of cancer cells is increasing, so it is possible for it to take advantage of others.

Because it is too tired and too busy.

At this time, the probability of getting cancer will increase tenfold or dozens of times.

This is why doctors often remind patients to quit smoking and eat less carcinogenic foods such as pickles, cured fish and bacon.

This does not mean that eating these foods will definitely cause cancer, but it will greatly increase the probability of getting cancer. (End of chapter)

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