Oncology Physician Life

Chapter 20 Chapter 19
The hospital is just one street away from Dong'an Sancun. Standing in the office of the laboratory building, you can clearly see the model senior high school next door.Every morning at 08:30 is the time for the school to do morning exercises, and you can see a long queue on the plastic playground.

This seems to have become a regular habit of Pei Xiaonan every day. When it is 08 minutes before 30:10, she will hold a cup of steaming black coffee and stand in front of the floor-to-ceiling windows, waiting for the students to run for exercise.

All schools in Shanghai basically have their own style of school uniforms. Compared with the rustic clothes of their time, the school uniforms of students are more westernized now. Blue suits are matched with red straight ties. Girls can wear beautiful blue school skirt.

As the music played on the school radio, the students lined up and ran against the wind in a neat and tidy manner.Pei Xiaonan recalled that when she was in high school, her finances were very tight, and her grandfather’s pension alone could barely cover the cost of books and exams. At that time, getting a scholarship was Pei Xiaonan’s only task. Either do the paper again, or on the way to do the paper again.

Her childhood was not good, it was very boring. The pain of her original family affected her first half of her life, so after graduating from university, she decided to enjoy her life and live the rest of her life according to her own wishes. Fortunately, her material requirements were not high. Gao, still has some patriotic feelings and artistic appeals, she is not interested in those famous bags, especially after studying in Italy at the university’s public expense, and seeing the production process of those so-called world famous bags, she is not interested in those things on the counter , I can no longer arouse any interest in buying.

Perhaps it was because she was engaged in tumor research, and she was only over [-] years old, which made her think about the value of life. When a person suffers from an incurable disease one day, and life is counting down, what will she do?What are you thinking?
Pei Xiaonan still can't answer this answer, her mind and heart are empty.

But Pei Xiaonan still has regrets about her childhood. She didn't enjoy the happiness of her childhood, the happiness of her student days. Every time she looked at the enthusiastic high school students on the playground through the window, she would think of the clothes she wore in high school. She looks like an old school uniform with ponytails and black-rimmed glasses, especially in summer, when she has no beautiful clothes to wear, every time in outdoor class, there will always be a group of annoying boys crowded together and laughing at her not fashionable.But she thought to herself, what fashion do students want?Just study well, she comforts herself like this every time.

The other well-off female students in the class would not play with her either. She was like a lonely individual, so she could only attribute it to the fact that she did not have the so-called princess life, but fortunately she did not suffer from that princess disease.

The mobile phone on the desk lit up for the 38th time. It was a message from my boyfriend Cheng Ge. The two had a big fight in the western restaurant yesterday.Cheng Ge almost roared and asked her, since she loves him, why can't she give up her job for him.

Now recalling her boyfriend's face, Pei Xiaonan sneered silently. Although she does not reject being a housewife, because having a girl is to pursue a happy family life. It can only be said that everyone has their own ambitions, but her ambition is a bit big. She doesn't want to just be a housewife. Compared with being a housewife, she wants to be a scientific researcher who has won a national key scientific research award in cancer research.

The mobile phone on the desk kept ringing, and it was Cheng Ge calling again. She didn't know how many times she hung up on him, and she thought Cheng Ge on the other side of the phone must have been blown up.

"Your iced Americano has no sugar."

The door of the office behind her was pushed open, Wei Ran in a purple suit came in with the coffee she just bought, and put it on her desk.

"Old Wei, do you think Cheng Ge doesn't want to live anymore?!" Pei Xiaonan raised her beautiful eyes, "Aren't you men all selfish animals, and you only think of everything for your own sake? What did it become? A tool for carrying on the family line and only having children?"

Wei Ran encountered Pei Xiaonan's soul torture as soon as he entered the door. Based on the time he spent with her in the past ten years, he didn't need to think about it, it must be that Pei Xiaonan and Cheng Ge had quarreled again.

"Actually, when two people are together, the most important thing is to be considerate of each other. Otherwise, you would answer Cheng Ge's call? Have a good talk with him?" Wei Ran carefully proposed a plan.

"There's nothing to talk about, let's destroy it, I'm tired." Pei Xiaonan shrugged indifferently.

Wei Ran sighed, based on his understanding of Pei Xiaonan, when she gave up her desire to survive, the biggest possibility was that she didn't want to continue playing with you, but she had already made a choice in her heart.At the beginning, Pei Xiaonan and Cheng Ge almost fell in love at first sight, just like in all TV dramas, childhood sweethearts were defeated by heaven.

From university to postgraduate entrance examination, to work, Wei Ran is the only male friend who has been with Pei Xiaonan in the past ten years. The other male friend is Ji Han. Even the students in the university think that they will finally be able to lead Pei Xiaonan closer. The person in the marriage hall will definitely be one of him and Ji Han.

It's a pity that since graduating from university, Pei Xiaonan's boyfriends have changed one after another, so much so that his classmates have ridiculed him, Wei Ran, who is iron, and boyfriend who is flowing.

He still remembered that three years ago, Pei Xiaonan happily called and told himself that she had found the best marriage partner, Cheng Ge, who was outstanding in appearance, good in family background, good in education, good in character, and the main reason was Cheng Ge To be honest, the love experience is very simple.Wei Ran is also very confused about this woman's mate selection criteria. Could it be that there are really girls who regard a boy's "honesty" as the first criterion for marriage?
Pei Xiaonan has her own set of criteria for choosing a mate. Compared to a man's family background, education, and appearance, these can only be said to be the superstructure of a building, while character is the foundation. Otherwise, no matter how gorgeous the building is, the foundation will collapse. The houses are gone, and they are just a pile of useless ruins.

Pei Xiaonan said that looking for a husband is like a high-risk career as a celebrity. Being handsome is not a necessary condition for you to become a hit, but to become a hit, you must look good, but once there is a problem with the celebrity's character, the person is set in the fans No matter how perfect it stands in front of it, it will be a matter of time before the house collapses. After seven or eight years of hard work in pretending, PC was arrested, everything is just passing by, and the man is still "honest" and reliable.

Once Pei Xiaonan made a decision, she would never regret it. She cleared all the dynamics with Cheng Ge in her circle of friends. Her circle of friends never set permissions. With such dynamic nature, she never gave herself a way out.

Picking up the phone, Pei Xiaonan sent a new Moments post: "Men are really unreliable things, women are on their own, fighting!"

Wei Ran touched his nose, this sentence is like including himself.It just so happened that head nurse Sun sent him a message that there was a patient in the ward who was in a condition, and he was urgently needed to go there.

Pei Xiaonan waved his hand impatiently, and dismissed him casually: "Queen, I'm a little tired, please step back, thank you for today's coffee!"

On the other hand, after Jiang Li went to work today, after properly arranging Xiao Jianghao's operation on the agenda, he walked towards the office of the director of the oncology department.

At this time, besides Liu Chong, there was also Cai Dazhi, the director of the laboratory of Saman Technology Company, in the director's office. The 43-year-old Cai Dazhi looks a little younger. In front of him is a boiling teapot, and a few pieces of Longjing tea leaves from Yuqianlongjing are constantly tumbling up and down in the boiling water.

Liu Chong was sitting behind his desk signing the latest documents. He put down the pen in his hand and looked at the cancer diagnosis and treatment center building outside the French windows.If the cooperation with Saman Technology Company can be successful this time, and the third-generation DK immunotherapy, which is a "dendritic cell-cytokine-activated killer cell" hybrid therapy, will be introduced, then the oncology department of the hospital will, under his leadership, Step into the next era, step into the era of true immunotherapy.

You should know that the current hospital is still using the first and second generation of cell therapy.

The first generation of cell therapy was LAK cell therapy, so-called lymphokine-activated killer cells.Its basic principle is to extract cells from the peripheral blood of patients, and then use "human interleukin-2" (IL-2) in vitro to induce the production of "killer immune cells" that can kill cells, and finally put these " Killer immune cells" are infused back into the patient.

Since 20 years ago, some experts have said that LAK has a certain effect. Unfortunately, in the past 20 years, countless clinical trials have proved the ineffectiveness and failure of LAK, so it has been completely eliminated by the hospital.

The second-generation CIK cell therapy, which is very similar to LAK, is theoretically stronger than LAK. However, large-scale clinical trials have not yet proved the effectiveness of CIK.

Because of this, Liu Chong decided to cooperate with Saman Technology to introduce the third generation of DK immunotherapy against all opinions at the hospital meeting.

Cai Dazhi took a sip of hot tea, and looked at the young doctor sitting opposite him: "Director Liu has a lot of talents under his command. It is really enviable to have such talents as Professor Ji."

There was a bit of a smile on Liu Chong's face. A large part of the reason why DK immunotherapy was introduced so smoothly this time was because Ji Han was on his side. After all, in the oncology department, Ji Han is recognized as a knife. Many old leaders in the hospital trust and support him very much.

"Thanks to Professor Ji's strong support this time, I believe that after the introduction of DK, the oncology department of our hospital will be improved to a higher level."

Cai Dazhi remembered the matter of Zhang Xiaoyun, the sales manager of the company. The fact that the introduction of anticancer drugs did not go well this time was entirely due to the obstruction of the director-general of the scientific research group of the hospital. Is it outstanding, and achieved the position of deputy director of the laboratory at a young age?"

Liu Chong naturally heard about Pei Xiaonan's objection to Samam Technology's introduction of the laboratory's latest anti-cancer drug at the conference, but he did not make redundant comments on it. Expensive anti-cancer drugs of Saman Technology Company in foreign laboratories do not agree.

Just when the two were talking happily, there was a knock on the door of the office. Liu Chong looked at the person who walked in, which surprised him: "Director Jiang? Why are you looking for me at this time?"

Liu Chong has a deep impression on Jiang Li, including a few days ago, Dean Li personally called an intern to intercede. Of course, he would not think that this intern could have anything to do with the high-ranking dean. After inquiring, I found out that it was Jiang Li who asked Dean Li to come forward for this intern.

Of course, Liu Chong would not dismiss the dean's face because of an intern, so he could only change it day and night. After coordinating with the hospital office, the intern's punishment was revoked and changed to stay in the hospital for observation, but this matter still made Liu Chong With a stick in his throat, Jiang Li is openly challenging his authority as the chief of the oncology department!
After Jiang Li came in, he didn't expect Ji Han to be there, and his expression froze suddenly.Looking at Jiang Li, Ji Han frowned, feeling a bad premonition in his heart.

Jiang Li looked at Liu Chong and said, "Director Liu, I actually came to you for the introduction of the third-generation DK immunotherapy in the hospital!"

"Oh?" Liu Chong was a little surprised by these words. He glanced at Cai Dazhi, the director of the Saman Technology Laboratory sitting next to him, and introduced, "I didn't expect that Director Jiang also has research on cell therapy. I just want to introduce it to you." For a moment, the person next to me is Mr. Cai Dazhi, the director of the Saman Technology Laboratory, and this is Jiang Li, the director of the new Pediatric Oncology Department of our Oncology Department, who came back from the MD Anderson Cancer Center at the University of Texas."

Cai Dazhi nodded to Jiang Li: "I didn't expect Director Jiang to be so powerful at such a young age!"

Liu Chong smiled, and took a sip of tea: "Mr. Cai, don't underestimate people. Our Director Jiang is a professor of surgery at MD Anderson Cancer Center, and he has also won the honor of National Rising Star in Surgery. What does this mean? It means that I am Professor Jiang. Ability and realm, enough level!"

Jiang Li was not in the mood to listen to such flattery and compliments, so she said bluntly: "I don't think the hospital is suitable for introducing DK immunotherapy!"

Jiang Li's words were like thunder from a silent place, causing Liu Chong's eyelids to twitch, and his face became more serious: "Director Jiang, this is a unanimous decision at the hospital meeting, if you object..."

Jiang Li interrupted him: "Director Liu, DK immunotherapy, there is no large-scale clinical trial to prove that it is effective!"

"Whether it is effective or not will be known after the introduction!" Liu Chong retorted her words, "Moreover, the mainstream immunotherapy in many domestic cancer hospitals was the second-generation CIK and the third-generation DC-CIK therapy at the beginning. And it has complete clinical trial data in American laboratories!"

Jiang Li frowned: "However, whether it is CIK or the third-generation DC-CIK, they are all experimental products that failed in European and American trials more than 10 years ago, and after the failure of American clinical laboratories, they cannot be marketed, and they have announced that they have given up on the third-generation DC-CIK." DC-CIK therapy has been completely banned in China in 16."

Liu Chong smiled: "Director Jiang, the failure of the American experiment does not mean that we will also fail."

Jiang Li argued: "I don't understand why a product that has failed has to be put into use in China, and a lot of money and manpower have been invested. The main reason for the failure of DK therapy is unknown targeting and cancer immunity. Inhibition, although compared with the third-generation CIK therapy, DK therapy has increased targeting to a certain extent, hoping that through the guidance of dendritic cells, immune cells can kill cancer cells more effectively, but now from the existing From a clinical point of view, although the effect is there, it is also very limited, because DK cannot break through the second bottleneck of CIK therapy: cancer immunosuppression!"

Liu Chong's face was gloomy, and Cai Dazhi's face was also very embarrassed. Jiang Li almost pointed at his nose and shouted that he was a liar who swindled money.

"This matter has already been decided in the academy. Director Jiang should stop talking about it. Professor Ji Hanji also supports this matter. Director Jiang, you should learn more from Professor Ji. I think you should focus more on children. The oncology department is good."

Jiang Li was taken aback when he heard Liu Chong's words, and looked at Ji Han who was dodging his eyes in disbelief. He couldn't believe it. Ji Han knew that DK immunotherapy was ineffective, but he would actually help others!

A few minutes later, Jiang Li slammed the door out of Liu Chong's office, and Ji Han followed her closely: "Jiang Li, listen to me, this matter is not what you think, and the situation in the courtyard is more complicated. It's not as simple as you think!"

"I think it's simple!" Jiang Li was ignited by Ji Han's words, as if he had ignited a powder keg, "Ji Han, you are also a doctor, I would never have thought that you could do such a thing? Don't you know that the third generation of DK immunotherapy has almost no effect on cancer patients? Don't you know that this kind of experimental waste, imported into the country and introduced into hospitals, has no effect on their condition except to keep burning money for cancer patients? , and even delay their illness?"

Ji Han was stunned speechless: "Jiang Li, listen to my explanation. The situation in China is very complicated. In China, cell therapy is not supervised by the traditional new drug development, so it can be used directly by patients and can be charged. So domestic Many hospitals choose to cooperate with foreign biopharmaceutical companies to promote this treatment on a large scale, which involves the interests of too many people, and you cannot stop it by taking it for granted!"

Jiang Li turned around, looked at Ji Han, and laughed: "Ji Han, you also know that almost all clinical trials related to immunotherapy are in China, is this normal?! If everyone is like you, knowing that This is abnormal, if we don't stop it, then our domestic medicine will never develop, and we can just be a recycling bin for American experimental waste with peace of mind!"

The more Jiang Li thought about it, the angrier she became, and she looked at Ji Han coldly, she almost didn't recognize the man in front of her.

"Ji Han, do you know what you are doing? You are seeking money, not killing your life! You are not worthy of being an oncologist at all!"

(End of this chapter)