Bailuyuan, I am Bai Xiaowen

Chapter 127 Analysis
Smith: "This medicine is called quinine. I hope it will have some effect on him."

After taking the medicine, I waited for a while and watched the reaction.

It really works.

There was no sign of vomiting from the medicine for at least ten minutes.

The doctor is asking: "How do you feel now?"

"It seems to be a lot more comfortable."

The two doctors of traditional Chinese medicine were quite shocked. Could it be that this ghost old man can really cure diseases.

Although I don't like foreigners, it is always a good thing to be able to treat diseases.

After waiting for a while, the patient's feedback was better.

Western medicine may work faster.

After half an hour, he was able to get down to the ground.

The two doctors of traditional Chinese medicine showed expressions of horror.

There were so many plagues that Chang'an doctors were helpless to deal with, but a foreign Japanese was able to cure them.

Both of them are the most skilled doctors in Chang'an, and they are very happy to see that the patient has improved.

This disease can kill people.

The doctor of traditional Chinese medicine complimented: "Doctor Smith is indeed very skilled in medicine. What is the name of this medicine and where can I buy it?"

"Quinine, I only have a little. Chang'an probably doesn't have it. I have to go to Shanghai. One gram of quinine may be a little more expensive than gold."

The faces of the two doctors changed.

Same price as gold.

When the patient is well, they take the patient out.

"A foreign devil is a foreign devil. He sells big cigarettes in China, and the price is the same as silver. Now there is another drug called this thing, and the price is the same as gold. What is he thinking?"

The doctor was very angry.

"Foreigners can't believe it. Who knows what kind of sorcery he used. The name of this medicine is quinine, and it's also a harmful thing. Even if the plague is cured, it will be infected with other things, which will be more serious."

After returning, continue to study Fang Zi.

Two days later, Bai Xiaowen also heard the news that the plague was coming again.

I hurried back and told my family that there was no need to go out.

In an era when even a cold would kill a person, the plague was even more serious.

Bai Xiaowen comes from a later generation and knows that the most effective way is isolation.

Bai Xiaowen went to the lower provincial capital to see the situation.

It turned out that this case was different.

The previous recipe was useless.

I went to a few pharmacies and heard that a foreign doctor cured one.

Bai Xiaowen is going to visit.

"Mr. Smith, do you know about this plague? Is there any way to treat it?"

"All I know is that quinine works."

Bai Xiaowen had some knowledge of the medicine quinine, which was specially used to treat malaria.

"Mr. Smith, can you sell me some?"

"Is there anyone in your family who is sick?"

"No, but I'd like to have some."

Compared with safety, money is nothing to Bai Xiaowen.

Smith was about to give medicine when suddenly several people came.

Bai Xiaowen seemed to have some impression that he was a wealthy boss in the county.

"Doctor foreign, I heard that you can cure plague, right? The medicinal materials for treating plague are equivalent to gold. I will buy it."

He came here as soon as he caught the disease.

News of the death had reached the city.

Because some of the villagers there have fled to the city.

Bai Xiaowen took some quinine.

Prepare for analytical research.

Let's see if we can get some generic drugs.

I visited several patients.

These cases were found.

It seems to be that kind of malaria.

Now Bai Xiaowen suddenly found a way.

You can use wormwood.

Artemisinin is specifically designed to deal with this stuff.

Extraction of Artemisia odorifera liquid can be carried out.

Do it immediately.

Go to the mountains and wander around.

Bai Xiaowen has studied Chinese medicine with Mr. Leng for so many years and has gone to the mountains to collect many herbal medicines.

I've seen wormwood before.

I spent a long time on the mountain.

A lot of Artemisia annua was caught.

According to medicinal records, Artemisia annua is an annual herb.The plant is fragrant.The main root is single and vertical, with few lateral roots.The stem is solitary, with many branches in the upper part, green when young, with vertical stripes, and the lower part is slightly lignified, slender, and hairless.Both sides of the leaves are green or light green, hairless.

The basal leaves and the lower stem leaves are divided into three-ringed pectinate pinnate shapes and have long petioles. The leaves wither during the flowering period.The middle leaves are oblong, oblong-ovate or elliptical.

Bai Xiaowen collected a lot.

Start making.

Daily medicines that are effective by decoction can be extracted with highly polar solvents such as water and ethanol. For those that are ineffective by boiling artemisinin, use less polar solvents such as petroleum ether.

Then separate.There are dozens of compounds in the extracted solution, and column chromatography is usually used, which is what we often call column flushing.

The workload is heavy, boring, and the technical content is low.A master's degree in future generations may do this every day for two years while doing experiments.

But Bai Xiaowen doesn't need it. He has spatial ability and the process increases hundreds of times.

Almost there, it’s time to start clinical trials.

Later generations have experimented with artemisinin, which was used to treat malaria.

There are many, many compounds identified in plants in later generations, and those with clear medicinal effects are definitely a drop in the ocean. Most of them are still screened for activity, and the activity is tested on animals before entering the clinic. However, the vast majority of them will be used for clinical purposes. The side effects were too strong and were withdrawn. Therefore, a compound extracted from a plant has to go through many verifications from extraction to patent medicine. The cycle may be as long as ten years or more, requiring the efforts and sweat of countless scientific researchers.

There are many methods for extracting the active ingredients of crude drugs. First, it is necessary to clarify what type of substances are extracted, whether they are alkaloids, quinones, flavonoids, terpenes or steroids.Extraction methods for different substances vary greatly.

Determining the type of matter is a huge project, and you can imagine how difficult it is.After determining the type of substance, determine its properties, and then design an extraction method based on its properties.The extract is obtained by dipping, decoction, and refluxing, and then various solvents are added for extraction and separation, such as acid extraction and alkali precipitation.

Although it has been determined, it cannot be done quickly if there is no space.

After preparing the medicine, Bai Xiaowen took the medicine directly to various pharmacies and claimed that it could cure diseases.

Many people are not good enough, but some believe it.

Some pharmacies in the provincial capital have also heard of Bai Xiaowen's name.

Especially the people at the drug store. A few years ago, there was a plague in Bailuyuan, but they handled it very well.

Another day passed.

There are dozens more patients.

The good news for the time being is that there are no dead people in the city.

The leaders of the provincial capital were also very anxious at this time.

I also met with many doctors in the provincial capital to inquire about the situation.

He said he wanted to invite a famous doctor from other places, so he hurried to arrange it.

In one family, a woman was cooking and fell directly to the ground.

"My mother, what's wrong with you, please don't scare me."

"Dizzy, I get dizzy after walking two steps."

Most people in the city now know the news of the plague.

Quickly helped his wife to bed to rest.

At this time, a neighbor came in and said, "Sister Wang, you are so skillful, I still need your help to clean up these shoes."

It turned out that the person was lying on the bed.

Coincidentally, I saw people vomit.

The person who came in turned pale all of a sudden, and was very frightened, for fear that he would also be infected.

Covering his mouth and nose with his hands, he hurried out.

I am afraid that if I slow down a little bit, I will also be infected.

I was very scared when I went out.

"What's wrong with you, you're in a panic."

The neighbor asked about the situation.The aunt gasped heavily and said, "It's not good, the people in that family are sick, so don't go to his house."

"Which one?"

"Sister Wang's house, you don't know what it's like anymore. You vomited all over the floor. That's plague. I can't even run away."

"Unlucky. Why did we become neighbors with her? Now my family is in trouble."

The disease came on relatively quickly.

The voice of the patient talking on the bed was much weaker, "I want to drink water."

"You wait, I'll get it for you right now."

Her husband brought a bowl of water.Suddenly I thought of the medicine I bought at home.Just that Artemisia annua.

"Daughter-in-law, come here, drink the medicine and you will be fine."

He was comforting his wife, and also comforting himself.

"What kind of medicine is this?"

"I bought it at the drug store. It is said to be able to cure diseases."

"Would it work? I guess I've got the plague, otherwise that aunt wouldn't have run so fast just now, like seeing a ghost."

"It will be fine, come, drink medicine."

He asked his wife to drink the Artemisia annua liquid.

"How's it going, wifey, do you feel better now?"

This man loves his wife more.

"It's really a fairy medicine. It can't be cured just after taking it, but it does feel a little better."

Gradually, it got better a lot, and the voice of speaking became louder.

The husband soaked her in a small amount of artemisia annua liquid.

"Drink it again, it will be fine."

After taking the medicine twice, my wife's condition has improved greatly. Although she is still a little weak, she can already walk.

After a while it was even possible to work.

The husband was very happy. He knew that this was the effect of Artemisia annua liquid.

After lying in bed for a whole day, from morning to afternoon, she wanted to go out and have a look.

When she went out, those neighbors avoided her like a ghost.

"Isn't she sick? How can she come out and walk around?"

Looking very scared.

Who is not afraid of plague.

People are dead outside the city.

The situation in Chang'an is also quite serious, but fortunately no one has died yet.

"Is she really suffering from the plague? You can see that she walks so steadily. I have seen people suffering from the plague. They all look terminally ill, how can they walk like this."

"It's impossible. I clearly saw my wife vomiting in the morning."

She was also puzzled.

When I saw him in the morning, he was lying on the bed, his face was pale, he looked weak and vomited, so what else could it be if it wasn't a plague.

I have good eyesight, so I can't make a mistake.

My wife went out for a walk and looked very good now.

Only slightly worse than normal.

Slowly, neighbors began to come over to say hello to Sister Wang.

"That Aunt Li is really serious. Sister Wang, you are doing well. She actually said that you have contracted the plague. How can you be so cursed?"

"I don't know if it's true. I was really sick in the morning, but now I'm all right. My husband gave me some medicine."

"You fell ill this morning? What were your symptoms?"

"I just feel hot all over, and then I have no energy, chest tightness and nausea."

"Isn't this the plague? I heard people say that this is the symptom of the plague. It's incredible that you recovered. What kind of medicine did your husband give you?"

"Artemisia annua liquid."

"Artemisia annua liquid?"

"Where did your husband buy it?"

"The drug store is not far away."

With successful cases, more people will come to buy medicine.

"Shopkeeper, I want a piece of Artemisia annua liquid."

"Shopkeeper, I want three portions, also of Artemisia annua liquid."

"I want it too, I want it too."

The drug store immediately began to greet them.

Dozens of packs were sold at once.

The number of people who became ill began to increase slowly.

Even up to hundreds of people.

Every hospital has so few patients.

Most of them are just lying in their own homes.

"I bought Artemisia annua liquid. I heard others saying that Artemisia annua liquid can cure plague."

"Where did you get this?"

"Bought for a thousand-dollar house."

"Is it reliable? I also heard that a member of the staff was cured of the plague. The medicine cost one tael of gold to buy, so it's expensive. This one only costs two cents."

"Whether he can do it or not, try eating first."

There is no need to boil medicine.

They are all particles.Or the liquid is ready.

Just rinse with boiling water or even warm water, which is very convenient.

After drinking a bowl of Artemisia annua granules, go see the reaction.

After about 10 minutes, the patient improved a lot.

It's like taking a fairy medicine.

Only 10 minutes later, the patient sat up from the bed. .

"You finally woke up."

The family is very happy.

"Let me see, let me take a good look."

Another one was cured, and the news that Artemisia annua liquid can treat plague began to spread slowly.

Soon Bai Xiaowen also knew it, and sighed in his heart, "It is indeed effective."

I also did a lot in space.

Fortunately, there are a lot of wormwood on the mountain.

Pharmacy store, "Don't be crowded, there are plenty of medicinal materials in the warehouse. There will be no shortage of supplies. Don't worry, I guarantee that everyone will have it."

The leaders of Chang'an are worried.

At this time, the secretary trotted over and said, "Good thing, good thing."

"I'm having a headache, and I'm worried about any good things, unless this plague can be solved."

"It's really about plague. There is a medicine in the county called Qinghao Granules, which can treat plague. I've seen it and it's really effective."

"Indeed."

"really."

"Then what are you waiting for? Prepare more medicine and be more prepared."

Such a big problem can be solved.Many experts in the provincial capital have not yet come up with a prescription. The plague is more serious than the last time.

Bai Xiaowen’s space is still being created.

There are still relatively few patients in provincial capitals.

The medicines prepared are enough.

Making money is secondary. Bai Xiaowen's idea is to make people die less.

If a plague is not dealt with properly, a large number of people will die.

Quinine is more expensive than gold.

This wormwood is cheap.

If this is cultivated in space, it may not cost a dime.

Continue to improve this artemisinin in the space.

It can only be used a few times in total.

(End of this chapter)