Xueba’s medical black technology system

Chapter 117 The three-month countdown begins

"Teacher, I'm going back to the dormitory first."

Lu Liang took out his luggage from the trunk of the car, and then said to Ji Hong in the car.

Just when Lu Liang was about to leave, Ji Hong suddenly spoke: "By the way, Xiao Lu, how did you know about the research on hepatitis C virus?"

Ji Hong had always had this question after coming out of the Drug Research Institute, but he still couldn't help but ask it now.

He remembered that on the way here, Lu Liang really just flipped through his phone.

Logically speaking, it is impossible for Lu Liang to have such an in-depth understanding of the hepatitis C virus.

Lu Liang scratched his head: "I have had the idea of ​​making hepatitis C drugs before, so I have read the relevant papers, so I still know a little bit about hepatitis C."

"So it is."

Ji Hong nodded suddenly: "Go back and rest early. You still have a lot of things to do in the next few months."

"Teacher, I'll go first then."

Lu Liang nodded, then took his luggage and walked towards the school dormitory.

After returning to the dormitory, Lu Liang simply took a shower and then threw yesterday's unwashed clothes into the washing machine.

After doing all this, Lu Liang sat down in front of the computer and began to think about hepatitis C drugs.

First of all, compared to the drugs analyzed before, he needed to analyze two different drugs this time.

One is an NS5A protein inhibitor.

The other is an NS5B polymerase inhibitor.

Moreover, this time he only had three months, and the time was tighter than before, so he needed to complete the experiment and get the data out in the shortest possible time.

In a sense, the task is not as heavy as usual.

Lu Liang held his breath and concentrated, and the system interface appeared in front of Lu Liang's eyes.

[Level: lv4]

[Analysis target: daclatasvir hydrochloride]

[An NS5A protein inhibitor that can inhibit viral RNA replication and virus particle assembly, and curb viral replication. 】

[Source points required for analysis: 2.5]

[Existing source point: 6.3]

[A new type of NS5A protein inhibitor + NS5B polymerase inhibitor can be obtained through analysis. 】

[Start parsing? 】

Lu Liang directly chose to analyze, and a large amount of information poured into Lu Liang's mind like a torrent.

After thinking carefully for a moment, Lu Liang suddenly opened his eyes.

That's right, it's this thing, sofosbuvir + velpatasvir.

Velpatasvir is an NS5A protein inhibitor, while sofosbuvir is an NS5B polymerase inhibitor.

The combination of these two drugs can solve 6 different genotypes of hepatitis C virus at one time.

Lu Liang didn't hesitate. He opened the computer directly, created a new document in ChemDraw, and then started to draw the synthesis route of the drug.

Draw the raw materials, solvents, reaction conditions, and reaction time one by one.

After completing the drawing of the drug synthesis route, Lu Liang wrote the patent application together and then completed the submission.

Later, he sent the synthesis routes of the two drugs to Tian Li.

After doing all this, Lu Liang thought about the experiment.

Compared with other experiments, this experiment is not simple, and can even be said to be a little dangerous.

Because the subject of the test is a virus!

Biological laboratories will divide the degree of danger into four levels according to the microorganisms they handle and their degree of hazard.

Different levels of biological laboratories are equipped with different safety equipment and can handle different microbiological tests.

Level one is the lowest and level four is the highest.

The first-level biological laboratory can only handle microorganisms that are not harmful to healthy adults, such as common bacteria and fungi such as E. coli.

Level [-] laboratories are suitable for highly dangerous pathogenic bacteria, such as the famous Ebola virus, hemorrhagic fever virus, etc.

The subject of Lu Liang's test this time is hepatitis C virus. In terms of safety level, the biosafety level of hepatitis C virus is two.

In other words, only second-level biological laboratories can conduct this kind of test.

Therefore, if Lu Liang wants to conduct experiments now, he needs to face three problems.

The first problem is cells. He needs cells to do experiments.

The second problem is the secondary laboratory. If you want to do hepatitis C virus testing, you need a secondary biological laboratory. Their pharmacy major does not have a secondary biological laboratory!
The third question, and the most important question, is where to get the strains of hepatitis C virus!

Lu Liang couldn't help but sigh.

The first problem is easy to solve. Cells can be purchased from those biological companies. For Lu Liang, any problem that can be solved with money is not a problem.

The second and third questions are more difficult.

After all, these two problems cannot be solved by money.

He couldn't build a second-level biological laboratory just to conduct an experiment, could he?
But then again, they are not the only pharmacy majors at the Pharmaceutical University.

There are also biology majors.

Although their pharmacy major does not have a secondary biology laboratory, it certainly does have one for the biology major.

At that time, you might be able to find someone with a biology major to borrow a biology laboratory.

Lu Liang told Ji Hong his thoughts, and Ji Hong agreed to the matter.

For him, this is just a matter of communicating with the school leaders, which is not too difficult to handle.

With Ji Hong's arrangement, Lu Liang felt relieved, as the matter of the secondary biological laboratory was settled.

Lu Liang silently crossed out the second question in his mind.

So, now there is only one last question left.

That's the strain of the hepatitis C virus.

Lu Liang felt a little overwhelmed for a moment, this thing was the biggest problem.

Because it is a virus, it is already destined to be impossible to have this thing in most places.

Lu Liang estimated that only places like the Centers for Disease Control and Prevention and Virus Control Centers are qualified to store hepatitis C virus strains.

However, there is one exception.

Although he is not qualified to preserve virus strains, the virus still exists.

That is in patients with hepatitis C.

But Lu Liang can't go to those hepatitis C patients with a cotton swab test tube and blood collection tube!

"Hey, brother, I want to do an experiment here. I'm interested in the hepatitis C virus. I see that you have a lot of hepatitis C virus in your body. Can you lend me some?" Isn't this just rubbing salt into other people's wounds?

Not to mention that he agreed, if he didn't get beaten up by Fatty, it was considered polite by the other party.

Moreover, even if the other party agreed, Lu Liang would not know what genotype the hepatitis C virus collected would be and whether there would be any mutations.

Isn't that a mess?

Therefore, hepatitis C virus must use strains stored in the virus bank of the Centers for Disease Control and Prevention or the Institute of Viral Disease Control.

But how to get the virus strains from these places?
After Lu Liang thought for a moment, he picked up his cell phone and dialed Chen Shen's number.

With his authority, he would certainly not be able to obtain the hepatitis C virus strain.

But Chen Shen is different. After all, Chen Shen is also the director of the Institute of Drug Research, and he still has some authority in this regard.

Soon, Chen Shen answered Lu Liang's call.

After learning about the problem Lu Liang encountered, Chen Shen pondered for two seconds: "Okay, I know the director of the Centers for Disease Control and Prevention. It should be much easier to apply for the strain."

After receiving Chen Shen's affirmative answer, Lu Liang couldn't help but breathe a sigh of relief.

Now that all the problems have been solved, we are just waiting for the samples of the drug and the hepatitis C virus strain to arrive.

Life Sciences Building.

in the office.

"Why, teacher, I finally made an appointment for the second-level laboratory."

Liu Yao couldn't help but ask.

Because the instruments in the laboratory are expensive, in order to save costs, university laboratories are basically equipped with only one instrument of each type.

However, because there are so many people using the instrument, conflicts sometimes arise over the use of the instrument.

Sometimes, there are even quarrels over the use of instruments.

Therefore, in order to prevent this situation from happening, most laboratories, instruments and laboratory use require reservations and queues in advance.

After the people in front of you have used up, and it's your turn on the list, you can use it.

Liu Yao also made an appointment a month in advance and waited in line for nearly a month before getting access to the secondary laboratory and instruments.

Originally, Liu Yao was planning to take advantage of these few days to complete her experiment as soon as possible.

After all, if she couldn't finish it, she would have to make another appointment, and she didn't want to wait that long.

But just today, she suddenly received a message from her supervisor, saying that her use of the laboratory would be postponed for a while.

This made Liu Yao a little unhappy. You should know that she had already prepared the experimental reagents and other things, and was just waiting for her turn to use the laboratory today.

Liu Yao's instructor took a sip of water and said, "The dean informed me of this matter."

"Is it the dean who wants to use the secondary laboratory?" Liu Yao asked cautiously.

The instructor shook his head and said: "It's not the dean, it's a student from the pharmacy major who urgently needs the use of the secondary laboratory, so let us be accommodating."

When Liu Yao heard this, she immediately felt furious: "Why? He wants to queue up by himself. What's the point of cutting in line?"

The instructor waved his hand to signal Liu Yao to calm down, and then said: "This matter is indeed urgent and it also takes up your time in the laboratory."

"So, I discussed it with the dean. After the laboratory is used up over there, I will arrange time for you to use the laboratory alone. It may be a little later, but it won't take long."

"Also, while he is using the laboratory, you can also enter the laboratory and do some preparation work."

This is equivalent to extending the date of use of the laboratory for a period of time.

After listening to her instructor's arrangements, Liu Yao's expression softened a lot and she reluctantly agreed.

After returning to her study room, Liu Yao returned to her study room.

A student next to him of the same grade asked: "Liu Yao, didn't you make an appointment in the laboratory today? Aren't you going to do some experiments?"

Liu Yao said with a depressed look: "Stop talking, a pharmacy student came from nowhere and came over to join my team. Now it's not my turn to use it."

Liu Yao's words immediately aroused the curiosity of others in the study room.

"No, the laboratories are all reserved for use. Why can that person jump in the queue, and he is a student from another college?"

"It's a close relationship. The dean has already agreed." Liu Yao said lightly, the disdain on her face becoming more obvious.

"Tsk, tsk, tsk, then this person's relationship is a bit tough. Can he make the dean nod in agreement? Is he an awesome doctoral student?"

"No, just an undergraduate."

"Undergraduate students, are you kidding me? Are you using this for fun in the secondary laboratory?"

"Hey, undergraduate students majoring in pharmacy, isn't that Lu Liang from their pharmacy department?"

This sentence made several people present stunned for a moment. Because of the previous sensational incidents, Lu Liang was now considered a semi-famous figure in the school.

It's just that he has basically never been seen. Everyone has only heard of his name, but they don't know what he looks like.

At this time, someone spoke weakly.

"That shouldn't be the case. If it's what he needs, the school can build him a second-level biological laboratory directly at the School of Pharmacy. There's no need to borrow it from us!"

"It does seem to make sense. If I were him, I wouldn't even bother using the new laboratory."

"If it's not that God Lu, then who is this undergraduate?"

"It's probably some related person who came to the laboratory to brush up on their qualifications. Anyway, it's all about human nature, so let's not worry about it."

"But, having said that, will he, an undergraduate, know how to use those instruments? Will he damage the instruments?"

As soon as these words were spoken, the expressions of several people present suddenly changed.

You know, a large part of the professional instruments in the laboratory are imported from abroad.

Once the instrument breaks down, there are only two solutions.

One is to ask specialized personnel from the company to come and repair it.

The other is to return the instrument to the original factory for repair.

It would be okay if the instrument company has a branch in China, but if not, that would be the most troublesome thing.

Therefore, one or two months must be necessary to return the instruments to the factory for repairs. They are still counting on these instruments for experiments!
Especially Liu Yao. She stood up suddenly and ran towards the laboratory slowly.

After obtaining the consent from the School of Life Sciences, Lu Liang took his things and walked towards the Life Sciences Building.

The drug samples had been sent over by Tian Li a few days ago.

Chen Shen also arranged for people to deliver strains of the Hepatitis C virus, which include six different genotypes.

Before arriving in front of the life science building, Lu Liang took out his mobile phone and glanced at the message Ji Hong sent him.

"Room 513, fifth floor, Life Sciences Building."

Room 513 on the fifth floor is the secondary laboratory. After Lu Liang took the elevator to the fifth floor, he walked along the corridor towards the laboratory.

Soon, Lu Liang arrived at the door of the laboratory.

Lu Liang put down his things and was about to reach out to twist the door handle of the laboratory when a voice came from behind Lu Liang: "Are you the undergraduate who wants to borrow the laboratory?"

(End of this chapter)