Chapter 46
"Is it so difficult to synthesize?"
There are a lot of nine-valent vaccines in the warehouse, including Glenin, which are mainly used for reference and analysis of previous project research and development.
Lin Zitai synthesized it hundreds of times and scrapped medicines worth more than 10,000 yuan, but failed even once.
If Will hadn't just thrown in some random items and produced [Strengthened Sildenafil Citrate] in just twelve attempts, he would have almost wondered if the system had become rusty after being unused for too long.
"If it doesn't work a hundred times, just two hundred times. If it doesn't work two hundred times, just three hundred times. I don't believe that I can't get the guarantee."
Lin Zitai also lost his temper. He called the warehouse manager and asked him to contact his partner and send a batch of medicines immediately.
"Merck's 60-price product and Novartis's Meglitinin, the 20-price product costs [-] doses, and [-] pills of Meglitinin comes in [-] bottles. It's not enough."
The warehouse manager was stunned, but did not dare to ask any more questions. He could only contact the pharmaceutical partner in a hurry: "Mr. Lin, Manager Hong said that they only have [-] doses at nine prices."
"Then let them deliver four hundred doses first."
"Also, when the medicine arrives, there is no need to put it in the warehouse. It can be sent directly to me."
Lin Zitai returned to the office, took a nap, played a few more games of Landlord, and waited for more than three hours.
Towards evening, Jinhua Biopharmaceutical’s transport refrigerated truck arrived at the company’s doorstep.
Four boxes of nine-price vaccines, each box contains 100 doses. The wholesale price is 1200 yuan per dose, with a total value of 48 yuan.
The wholesale price of 20 bottles of 60-capsule Glenin is 1.6 yuan each, with a total value of 32 yuan.
The former is a vaccine for women to prevent nine diseases, and it can be taken or not. The latter is the real life-threatening medicine.
Patients with chronic myelitis in the middle and late stages need to take two pills a day. A bottle of 60 pills costs 1.5, which is only a month's supply.
Even though Glenin is now covered by social security, a bottle still costs 4500 yuan, which is [-] yuan a year.
There are about 16 chronic myeloid patients in China, and about [-] patients in the middle and late stages.
At least [-] bottles of Glenine are consumed every month, and the price purchased by the state will be lower than the wholesale price in the market.
However, based on the selling price of the Social Security Bureau as a reference, the purchase price between the official and Novartis Group should not be less than 1 yuan.
9 million per month and 108 billion per year. This is only the sales volume of one country. The developed countries of Japan, South Korea, Europe and the United States have not been included.
If the sales in various countries around the world are counted, the conversion unit of 108 billion will probably be converted into US dollars.
This is indeed the case. Novartis Group’s net revenue last year was US$158 billion, and Grenin held a 75% share.
The pharmaceutical industry is not without huge profits.
"For the sake of all the people in the world, do it for me!"
Each synthesis requires four pills, each worth 266 yuan, and the cost of one synthesis is 1066 yuan.
Lin Zitai forgot how many times he synthesized it, like a ruthless robot that only refills ammunition.
Unconsciously, 20 bottles of Glenin, totaling 1200 pills, were more than half consumed. When he wanted to doze off, a golden light suddenly appeared in front of his eyes.
[Fortified imatinib mesylate tablets]
"Damn, I finally got the guarantee."
Lin Zitai carefully put away the yellow pills and turned his attention to the nine-valent vaccine.
Four hundred doses can be synthesized a hundred times, and finally on the fifth to last time, the golden light appears again.
[Enhanced·Nine-valent virus vaccine]
Lin Zitai stared at the two drugs and fell into deep thought.
After thinking for a while, he put the nine-valent vaccine into the incubator, locked it in the safe, and called Cheng Zhiyu to ask him to come over.
The elderly are old and cannot bear the stimulation, so it is difficult to take out one drug at a time.
If he took out two items at once, Lin Zitai was worried that his blood pressure would suddenly spike and he would not be able to accept this fact.
After all, he was using the Nanya Laboratory as an excuse. Since others could develop it, why couldn't he? It was because he was not as capable as the other party.
Therefore, the nine-valent vaccine still needs to be delayed for a while before being released.
Cheng Zhiyu came in a hurry, with deep grooves on his cheeks, the marks left by wearing a protective mask for a long time.
"Academician Cheng, please take this pill and analyze it."
Lin Zitai took out the yellow tablets and placed them on the table. Cheng Zhiyu frowned: "Imatinib mesylate tablets?"
Over the years, he and his team have conducted hundreds of experiments, and when he saw the yellow pills, he subconsciously thought of Glenin.
"Yes, this is a brand new, upgraded and improved version. You can take it for drug analysis to see if it infringes on the drug patent, and how it is different from the third generation version launched by Novartis."
Cheng Zhiyu was in a daze and suddenly froze because he remembered Lin Zitai's last demonic power and said the same thing at that time.A brand-new synthesis method allows it to have refreshing and anti-fatigue effects without the need for taurine and caffeine.
"it is good."
Cheng Zhiyu was excited, picked up the yellow pills and went straight to the laboratory without even closing the office door.
Lin Zitai laughed in surprise. He had been used to it for a long time and could understand it. After all, Cheng Zhiyu's character was like this.
He doesn't understand the ways of the world, and he doesn't understand flattery. He focuses entirely on his own related fields.
It was estimated that he wouldn't be able to analyze it for a while, so Lin Zitai left the company decisively and returned to Ye Xiyue's home.
After dinner, a man and two women watched TV for a while, and then went back to their rooms to rest in the early morning.
In a daze, Lin Zitai was woken up by a phone call.
On the other end of the phone, Cheng Zhiyu was so excited that he spoke incoherently: "It's the same as Mo Jin, it's just like Mo Jin."
"What is the same as magic power?"
Lin Zitai rubbed his eyes, turned on the bedside lamp, and glanced at the alarm clock, which read four-fifteen in the morning.
He cleared his throat and said with a wry smile: "Academician Cheng, you shouldn't have been studying since this afternoon, right?"
"Those don't matter."
Cheng Zhiyu was very excited and said to himself: "This is another brand-new way of solving problems. If we can master and use this technology skillfully, it will be a blessing to all mankind."
Lin Zitai's heart trembled: "Academician Cheng, I remember you said before that failure is common and success is accidental."
Cheng Zhiyu was silent, but unwilling to do so: "The previous magic power was like this, and so is Imatinib Mesylate Tablets."
He couldn't help but ask: "Xiao Lin, does your laboratory in South Asia have special technology?"
"There is no special technology, do you know? In order to improve and upgrade Novartis's Glenin, we have invested much more time, energy, money and material resources than you can imagine."
Lin Zitai pondered for a moment and had no choice but to make up a story. The reason why laboratories in South Asia are able to continuously innovate is because of high investment and low cost.
Domestic research and development of new drugs must first pass drug trials, and then pass experiments on mice and monkeys, with the two alternating multiple times.
It must pass multiple official reviews before willing patients can finally be recruited for clinical trials.
White mice range from 30 to 300 yuan each, while experimental monkeys are more expensive, costing at least 15 yuan each.
But in South Asia laboratories, there is no need for mice and experimental monkeys, because human lives are cheaper than animals there.
Official audits are in vain and only cost a few million dollars a month to manage.
"Academician Cheng, can you understand what I say?"
Cheng Zhiyu was shocked. There were already pictures in his mind, and he could only force himself not to think about those inhumane experiments.
Slowly exhaling a breath: "The efficacy of this new drug is about twice that of the third-generation glenin, and it can greatly inhibit the growth of human white blood cells."
"If the patient is in the early stage of mild disease, long-term treatment may be completely cured, but the specific situation requires long-term and multiple trials to slowly observe."
Lin Zitai asked: "Can we imitate it?"
"absolutely okay."
“What about drug patents?”
"This is a completely new way of synthesis..."
When Cheng Zhiyu talked about the ingredients of the medicine, his emotions that had just calmed down became excited again, and he talked a lot.
Lin Zitai looked out the window. At the end of the Pujiang River, a touch of fish belly white gradually appeared: "Teacher Cheng, the experiment is important, but it is not as important as your body."
"Well, you go home and rest first. I'll ask Mr. Liu to go back in the morning and approve 2000 million in funds first to set up a project team. You will be fully responsible for the team, including the first developer of this drug who also has your name on it. Down."
Cheng Zhiyu was stunned and said hurriedly: "No, you must not do this. I am just a copycat and I don't dare to take credit."
"Teacher Cheng, even if you are doing me a favor, you also know that the Nan Ya laboratory will never see the light of day."
Lin Zitai is sincere and sincere in his words. The company needs a spokesperson, otherwise the source of the drug cannot be explained.
Medicines are not drinks, not to mention that there is a certain probability of treating early-stage chronic myelogenous leukemia. Once the medicine is exposed, it will definitely be written up in a big book, and it may even be featured in the column of Station C.
The company needs a valuable spokesperson, an academician of biology from the Chinese Academy of Sciences, and this weight is just right.
Cheng Zhiyu wanted to refuse, but couldn't say it.
In life, some people are interested in fame and others are interested in profit. As long as the new drug can be successfully launched, it will definitely leave its name in history.
(End of this chapter)
"Is it so difficult to synthesize?"
There are a lot of nine-valent vaccines in the warehouse, including Glenin, which are mainly used for reference and analysis of previous project research and development.
Lin Zitai synthesized it hundreds of times and scrapped medicines worth more than 10,000 yuan, but failed even once.
If Will hadn't just thrown in some random items and produced [Strengthened Sildenafil Citrate] in just twelve attempts, he would have almost wondered if the system had become rusty after being unused for too long.
"If it doesn't work a hundred times, just two hundred times. If it doesn't work two hundred times, just three hundred times. I don't believe that I can't get the guarantee."
Lin Zitai also lost his temper. He called the warehouse manager and asked him to contact his partner and send a batch of medicines immediately.
"Merck's 60-price product and Novartis's Meglitinin, the 20-price product costs [-] doses, and [-] pills of Meglitinin comes in [-] bottles. It's not enough."
The warehouse manager was stunned, but did not dare to ask any more questions. He could only contact the pharmaceutical partner in a hurry: "Mr. Lin, Manager Hong said that they only have [-] doses at nine prices."
"Then let them deliver four hundred doses first."
"Also, when the medicine arrives, there is no need to put it in the warehouse. It can be sent directly to me."
Lin Zitai returned to the office, took a nap, played a few more games of Landlord, and waited for more than three hours.
Towards evening, Jinhua Biopharmaceutical’s transport refrigerated truck arrived at the company’s doorstep.
Four boxes of nine-price vaccines, each box contains 100 doses. The wholesale price is 1200 yuan per dose, with a total value of 48 yuan.
The wholesale price of 20 bottles of 60-capsule Glenin is 1.6 yuan each, with a total value of 32 yuan.
The former is a vaccine for women to prevent nine diseases, and it can be taken or not. The latter is the real life-threatening medicine.
Patients with chronic myelitis in the middle and late stages need to take two pills a day. A bottle of 60 pills costs 1.5, which is only a month's supply.
Even though Glenin is now covered by social security, a bottle still costs 4500 yuan, which is [-] yuan a year.
There are about 16 chronic myeloid patients in China, and about [-] patients in the middle and late stages.
At least [-] bottles of Glenine are consumed every month, and the price purchased by the state will be lower than the wholesale price in the market.
However, based on the selling price of the Social Security Bureau as a reference, the purchase price between the official and Novartis Group should not be less than 1 yuan.
9 million per month and 108 billion per year. This is only the sales volume of one country. The developed countries of Japan, South Korea, Europe and the United States have not been included.
If the sales in various countries around the world are counted, the conversion unit of 108 billion will probably be converted into US dollars.
This is indeed the case. Novartis Group’s net revenue last year was US$158 billion, and Grenin held a 75% share.
The pharmaceutical industry is not without huge profits.
"For the sake of all the people in the world, do it for me!"
Each synthesis requires four pills, each worth 266 yuan, and the cost of one synthesis is 1066 yuan.
Lin Zitai forgot how many times he synthesized it, like a ruthless robot that only refills ammunition.
Unconsciously, 20 bottles of Glenin, totaling 1200 pills, were more than half consumed. When he wanted to doze off, a golden light suddenly appeared in front of his eyes.
[Fortified imatinib mesylate tablets]
"Damn, I finally got the guarantee."
Lin Zitai carefully put away the yellow pills and turned his attention to the nine-valent vaccine.
Four hundred doses can be synthesized a hundred times, and finally on the fifth to last time, the golden light appears again.
[Enhanced·Nine-valent virus vaccine]
Lin Zitai stared at the two drugs and fell into deep thought.
After thinking for a while, he put the nine-valent vaccine into the incubator, locked it in the safe, and called Cheng Zhiyu to ask him to come over.
The elderly are old and cannot bear the stimulation, so it is difficult to take out one drug at a time.
If he took out two items at once, Lin Zitai was worried that his blood pressure would suddenly spike and he would not be able to accept this fact.
After all, he was using the Nanya Laboratory as an excuse. Since others could develop it, why couldn't he? It was because he was not as capable as the other party.
Therefore, the nine-valent vaccine still needs to be delayed for a while before being released.
Cheng Zhiyu came in a hurry, with deep grooves on his cheeks, the marks left by wearing a protective mask for a long time.
"Academician Cheng, please take this pill and analyze it."
Lin Zitai took out the yellow tablets and placed them on the table. Cheng Zhiyu frowned: "Imatinib mesylate tablets?"
Over the years, he and his team have conducted hundreds of experiments, and when he saw the yellow pills, he subconsciously thought of Glenin.
"Yes, this is a brand new, upgraded and improved version. You can take it for drug analysis to see if it infringes on the drug patent, and how it is different from the third generation version launched by Novartis."
Cheng Zhiyu was in a daze and suddenly froze because he remembered Lin Zitai's last demonic power and said the same thing at that time.A brand-new synthesis method allows it to have refreshing and anti-fatigue effects without the need for taurine and caffeine.
"it is good."
Cheng Zhiyu was excited, picked up the yellow pills and went straight to the laboratory without even closing the office door.
Lin Zitai laughed in surprise. He had been used to it for a long time and could understand it. After all, Cheng Zhiyu's character was like this.
He doesn't understand the ways of the world, and he doesn't understand flattery. He focuses entirely on his own related fields.
It was estimated that he wouldn't be able to analyze it for a while, so Lin Zitai left the company decisively and returned to Ye Xiyue's home.
After dinner, a man and two women watched TV for a while, and then went back to their rooms to rest in the early morning.
In a daze, Lin Zitai was woken up by a phone call.
On the other end of the phone, Cheng Zhiyu was so excited that he spoke incoherently: "It's the same as Mo Jin, it's just like Mo Jin."
"What is the same as magic power?"
Lin Zitai rubbed his eyes, turned on the bedside lamp, and glanced at the alarm clock, which read four-fifteen in the morning.
He cleared his throat and said with a wry smile: "Academician Cheng, you shouldn't have been studying since this afternoon, right?"
"Those don't matter."
Cheng Zhiyu was very excited and said to himself: "This is another brand-new way of solving problems. If we can master and use this technology skillfully, it will be a blessing to all mankind."
Lin Zitai's heart trembled: "Academician Cheng, I remember you said before that failure is common and success is accidental."
Cheng Zhiyu was silent, but unwilling to do so: "The previous magic power was like this, and so is Imatinib Mesylate Tablets."
He couldn't help but ask: "Xiao Lin, does your laboratory in South Asia have special technology?"
"There is no special technology, do you know? In order to improve and upgrade Novartis's Glenin, we have invested much more time, energy, money and material resources than you can imagine."
Lin Zitai pondered for a moment and had no choice but to make up a story. The reason why laboratories in South Asia are able to continuously innovate is because of high investment and low cost.
Domestic research and development of new drugs must first pass drug trials, and then pass experiments on mice and monkeys, with the two alternating multiple times.
It must pass multiple official reviews before willing patients can finally be recruited for clinical trials.
White mice range from 30 to 300 yuan each, while experimental monkeys are more expensive, costing at least 15 yuan each.
But in South Asia laboratories, there is no need for mice and experimental monkeys, because human lives are cheaper than animals there.
Official audits are in vain and only cost a few million dollars a month to manage.
"Academician Cheng, can you understand what I say?"
Cheng Zhiyu was shocked. There were already pictures in his mind, and he could only force himself not to think about those inhumane experiments.
Slowly exhaling a breath: "The efficacy of this new drug is about twice that of the third-generation glenin, and it can greatly inhibit the growth of human white blood cells."
"If the patient is in the early stage of mild disease, long-term treatment may be completely cured, but the specific situation requires long-term and multiple trials to slowly observe."
Lin Zitai asked: "Can we imitate it?"
"absolutely okay."
“What about drug patents?”
"This is a completely new way of synthesis..."
When Cheng Zhiyu talked about the ingredients of the medicine, his emotions that had just calmed down became excited again, and he talked a lot.
Lin Zitai looked out the window. At the end of the Pujiang River, a touch of fish belly white gradually appeared: "Teacher Cheng, the experiment is important, but it is not as important as your body."
"Well, you go home and rest first. I'll ask Mr. Liu to go back in the morning and approve 2000 million in funds first to set up a project team. You will be fully responsible for the team, including the first developer of this drug who also has your name on it. Down."
Cheng Zhiyu was stunned and said hurriedly: "No, you must not do this. I am just a copycat and I don't dare to take credit."
"Teacher Cheng, even if you are doing me a favor, you also know that the Nan Ya laboratory will never see the light of day."
Lin Zitai is sincere and sincere in his words. The company needs a spokesperson, otherwise the source of the drug cannot be explained.
Medicines are not drinks, not to mention that there is a certain probability of treating early-stage chronic myelogenous leukemia. Once the medicine is exposed, it will definitely be written up in a big book, and it may even be featured in the column of Station C.
The company needs a valuable spokesperson, an academician of biology from the Chinese Academy of Sciences, and this weight is just right.
Cheng Zhiyu wanted to refuse, but couldn't say it.
In life, some people are interested in fame and others are interested in profit. As long as the new drug can be successfully launched, it will definitely leave its name in history.
(End of this chapter)
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