Daming: My boss Zhu Yuanzhang

Chapter 248 Extraction of Penicillin

After Zhu Yuanzhang heard this, his eyes gradually narrowed and he stared at Mao Xiang intently.

Mao Xiang's heart suddenly trembled. He felt as if he was being targeted by a tiger, and his whole body tensed up involuntarily.

After a moment, Zhu Yuanzhang said in a deep voice: "Continue to investigate!"

"I obey the order!" Mao Xiang quickly replied.

"Well, step back!" Zhu Yuanzhang waved his hand.

"Yes, I will retire."

When Mao Xiang heard this, he immediately bowed and bowed and exited the Qianqing Palace.

After leaving the main hall, he felt the pressure ease and let out a long sigh of relief.

In fact, it was difficult for him to feel guilty. As a close confidant of the emperor, sometimes it was enough not to fulfill his duties faithfully. When the emperor felt that there was a problem with something, it had better be that there was really a problem. If you couldn't find the problem, Then there may be something wrong with you.

Although he had investigated very carefully, His Majesty clearly still didn't believe it. He also thought about fabricating some evidence, but he didn't dare to make any independent claims. He was in a dilemma for a while.

In Kunning Palace, the little palace maid fed Queen Ma to take the boiled Chinese medicine spoonful by spoonful, with Li Wei and An Qing accompanying her.

"How has the Queen been these days?" Li Wei asked An Qing beside him in a low voice.

An Qing frowned slightly and said, "Every time Queen Mother takes the medicine you gave her, her fever will go away soon, but the fever will come back within a few hours, and her body will not get better."

Li Wei sighed softly when he heard this. This situation was within his expectation. Antibiotics were not needed to eliminate the inflammation in the body. Just taking antipyretics was of no use.

"Please keep an eye on him. If the fever is severe, give him a pill. If the fever is not severe, don't take it."

Li Wei ordered softly.

An Qing nodded obediently, and then asked worriedly: "Can the Queen Mother's disease be cured?"

"Don't worry, it will definitely be cured." Li Wei comforted with a smile.

In fact, he was not sure, but now he could only comfort Anqing in this way.

After Queen Ma finished taking the medicine, Li Wei called Zhao Xuan and other imperial doctors over to discuss countermeasures.

If possible, he still hopes to use conservative Chinese medicine to treat Queen Ma. After all, the use of penicillin is still very risky.

"Do you have any other treatments for Queen Ma's illness?" Li Wei asked in a deep voice.

Faced with Li Wei's question, everyone was silent for a while. It was not that their medical skills were incompetent, but that Queen Ma's illness had been delayed for too long and was too serious.

Seeing this, Li Wei suddenly became unhappy and said coldly: "Everyone, now is not the time to evade. If anything happens to Queen Ma, your Majesty will blame her. No one can protect you!"

Everyone suddenly panicked when they heard this. After a while of whispering, Zhao Xuan finally said helplessly:

"Prince-in-law, we have tried our best, but sometimes our manpower is exhausted, and there is nothing we can do."

Other imperial doctors also echoed: "Yes, Prince Consort, Queen Ma has been ill for too long, and there is nothing we can do!"

Li Wei frowned, scanning everyone, and finally landed on Dai Sigong.

After getting along with each other these days, he also saw that Dai Sigong was indeed a good doctor with high medical ethics. When other imperial doctors faced this situation, they all avoided it, but he was the only one who dared to use medicine, even risking strong medicine.

"Dr. Dai, is there anything you can do?"

Li Wei asked unwillingly.

Dai Sigong looked up at him, remained silent for a long time, and finally shook his head gently. “Prince-in-law, is there anything else you can do?”

Imperial doctor Liu Chun asked back. When everyone heard this, they also looked at him expectantly.

The magic medicine Li Wei brought out two days ago reduced the fever so quickly, which opened their eyes. Although they also saw that it only treated the symptoms but not the root cause, since the consort could come up with a magic medicine Come, it may not be possible to come up with the second and third types.

Now they can only hope that the prince consort can create another miracle.

Facing their eager eyes, Li Wei felt disappointed. It seemed that these imperial doctors had no hope and could only wait for penicillin to be produced and take a chance!

"I have arranged for people to prepare a new medicine. It will be ready for use in a few days." Li Wei said.

When all the imperial doctors heard this, they were suddenly surprised. Dai Sigong also looked at him in surprise. They didn't expect that the prince-in-law could really come up with the second magic medicine.

To be honest, Empress Ma's current situation seemed to him to be beyond hope, but looking at Li Wei's intention, it seemed that he was quite sure that Empress Ma could be cured, which made him feel surprised.

Li Wei looked at the happy-looking doctors and sighed slightly in his heart.

Time passed slowly. Apart from occasionally sorting out the memorials that Zhu Biao had handled, Zhu Yuanzhang mostly stayed in the harem to accompany Queen Ma. An Qing also stayed in the palace to take care of his mother.

Those imperial doctors were spending their days like years, hoping every day that the new medicine Li Wei mentioned could be quickly produced to cure Empress Ma and help them survive this disaster.

Of course, Li Wei himself was also very anxious. Finally, when the seven days were up, he hurried to the Ordnance Bureau.

In the hut, the culture fluid in the glass bottles that Li Wei had previously sealed has turned into a solution containing a large amount of penicillin, and the penicillin can now be extracted.

He recruited the previous craftsmen to work together, opened the bottles, then took a funnel, used steamed and sterilized cotton as a filter, and filtered all the liquid into a large glass.

Immediately, add a large amount of vegetable oil to these liquids, stir and set aside.

Soon after, the mixed liquid separated into three layers, with the oil on top and the fat-soluble substances dissolved into the oil.

In the middle are insoluble impurities, and the bottom layer is the aqueous solution of penicillin.

Then separate these aqueous solutions through the water outlet under the glass, add the activated carbon prepared previously, and absorb these solutions.

Finally, these activated carbons should be washed three times, the first time with clean distilled water to remove impurities, the second time with acidic water to further remove alkaline impurities, and finally, with alkaline water, penicillin is washed out.

Penicillin is slightly acidic and soluble in alkaline water but not in acid.

The application of alkali solution in the soap making process is very mature, so there is no problem. The acidic water is made from vinegar.

After a day's work, Li Wei finally made several bottles of penicillin, but he still had to test whether they were effective.

Get some small bowls, take out some of these penicillins and pour them in, then scrape some staphylococci from the peritoneum of the mouth, drop them in, leave them for a few days to see the effect, if there is a circle-like reaction around it, it is effective, otherwise, it is Failed.

After sealing the remaining dozen bottles of penicillin so well, Li Weicai finally breathed a sigh of relief. Whether he could save Empress Ma would depend on the effectiveness of this penicillin.

He has tried his best to ensure aseptic operation during the production process. All utensils and materials have been sterilized with alcohol or steaming. But even so, this thing is very risky, and it may become sterile after use. There are adverse reactions, but the situation has come to this, so I can only take the risk and give it a try.

"Master Li, what are you doing?"

Luti looked at the water he had worked so hard to make, and couldn't help but wonder. In his opinion, Li Wei just turned the water over and over to make it dirty and clean, and in the end the water was still water.

"Haha, this is a medicine called penicillin, which can cure many diseases." Li Wei said with a smile.

Luti's eyes widened and he looked carefully at the penicillin made by Li Wei, but no matter how he looked at it, he felt that it was no different from water.

　I'm sorry to keep you all waiting. I've been busy lately, which has delayed me a lot of time and I'm slow in writing. I'm sorry, I'd like to mention that it's double monthly pass time these days. Well, I won't say anything and keep silent. Praying in front of the computer

　　

　

(End of this chapter)