Why do we say that ordinary heroic spirits are arbitrary for eternity?

Chapter 35 The first dose of antibiotics in the late Han Dynasty!

Chapter 35 The first dose of antibiotics in the late Han Dynasty!

Before the industrial revolution began, it was not that difficult to apply antibiotics by hand.

Antibiotics such as erythromycin and tetracycline have no chance at all.

Although penicillin can be produced manually, the output of Penicillium was pitifully small before modern industrial radiation selection.

Not to mention the cumbersome production process, even if it is produced, there are still a lot of impurities harmful to the human body that cannot be removed.

It's more of a poison than an antidote.

Under the medical conditions of the late Han Dynasty, it could only be taken orally. If you get a needle and try to inject it... that is simply asking for death.

He had a chance to survive the plague, but he died suddenly on the spot as soon as he was injected.

Relatively speaking, there is an antibiotic that is very suitable for manual extraction, the yield is relatively high, and the content of harmful substances is also very low.

In addition, the extraction process is much simpler. Even in ancient times without industrialization, manual extraction was still possible.

And its antibacterial ability is very good, and it has a wider range of antibacterial types.

Penicillin is only effective against bacteria but not fungi, but this antibiotic is one of the few antibiotics that can treat both bacteria and fungi.

The most important thing is that it is also suitable for oral administration!

The name of this antibiotic is allicin.

As the name suggests, it is an antibiotic extracted from garlic.

After entering the industrial era, the main users of allicin were livestock farms.

but.

Even antibiotics for veterinary use were still absolute miracle drugs in ancient times.

After all, if something can save lives, why do you care whether it is for veterinary use?
  The only problem is...

Was there garlic in the late Han Dynasty?
  Many crops in ancient times were imported and did not exist locally.

For example, peppers, tomatoes, potatoes, sweet potatoes, etc.

Including garlic, it is actually an exotic species.

Garlic originates from Central Asia and the Mediterranean region.

Fortunately.

There is garlic in Han Dynasty.

As early as the Western Han Dynasty, Zhang Qian was introduced to the Western Regions when he was on an envoy to the Western Regions.

It is known as "Hu Suan" in history.

It was later popularized, and by the end of the Han Dynasty, it was already one of the common crops.

……

Open your eyes and go back to the end of Han Dynasty.

Lu Yu took action immediately.

After getting everything ready.

The first experiment officially started.

Start by mashing the garlic until it becomes minced.

At this time, the alliin and alliinase in garlic collide and produce a decomposition reaction.

In this way, allicin is formed.

Leave it for another half hour.

Let it fully react, and the concentration of allicin at this time is the highest.

In principle, it is not easy to obtain allicin. Just make it into minced garlic and it will be generated automatically.

Allicin has a strong inhibitory effect on most cocci, bacilli, and even some molds, viruses, human parasites and other microorganisms.

Whether taken orally or applied externally, it has a very good antibacterial effect.

only.

If you want to completely turn garlic into an antibiotic, this alone is not enough.

Because allicin will further decompose at room temperature, and the content is too low.

Therefore, if you want to cure diseases by eating garlic, it is really a drop in the bucket.

Looking at the garlic that had fully reacted and smelling the pungent smell, Lu Yu said softly: "That's it now."

He picked up a jug of high-purity alcohol. High-concentration alcohol is also easy to make. Liquor can be obtained by drying it with quicklime and then distilling it.

In this era, there was distillation technology, but there was no distilled wine.

Through distillation, Lu Yu obtained a high concentration of alcohol, then soaked the garlic paste in alcohol for half an hour, and finally extracted the allicin solution through distillation.

This step can actually be replaced by water and extracted by steam distillation.

After all, garlic is not valuable, but wine is different. Especially high-concentration alcohol requires a lot of wine to extract, which cannot be promoted and applied at all.

The reason why high-concentration alcohol is used at this moment is just to extract the highest concentration of allicin solution.

Let’s see how effective this allicin solution is in treating plague.

If it really works.

Then just use water instead of distillation to extract it. Even if the content is slightly lower, it doesn’t matter, as long as it works!

With distillation extraction.

soon.

Lu Yu obtained some golden garlic solution.

It is relatively rich in allicin.

"I got the first dose of antibiotics in the late Han Dynasty."

Lu Yu looked at the translucent golden liquid, his eyes full of expectation.

Although extracting this kind of allicin is relatively simple, it has many disadvantages.

One is that it tastes pungent, and the other is that it is perishable.

After production, it must be taken as soon as possible. It is not suitable for long-term transportation, otherwise the effect will be greatly reduced.

But no matter how many shortcomings it has, as long as it can be effective, it is all worth it!
  Lu Yu called Kong Yue.

"Brother!" As soon as Kong Yue entered the room, he smelled the pungent smell of garlic and felt a little strange.

"Are any of our people infected with typhoid fever or plague?" Lu Yu asked directly.

"Not really." Kong Yue shook his head: "We all listened to my elder brother and wore silk cloth to cover our mouth and nose. The silk cloth was scalded and washed every day. Everyone drank hot water. We spread lime outside the house and were careful when entering and exiting. So until now No one has yet contracted the plague!”

"Brother's methods are definitely effective. It's a pity that many people in the church don't take this seriously. They still drink raw water and don't wash and change the silk cloth. It's really harmful to others and themselves!"

After hearing this, Lu Yu shook his head and said, "The habit of drinking raw water cannot be changed in a day or two, and there is no way to light a fire and drink water anytime and anywhere, and there is not enough firewood."

"I put forward these methods to nip the problem in the bud, but I also know that it is impossible to completely prevent it. As long as it has some effect, it will be good."

"By the way, find someone to take me to the camp for typhoid patients."

"Yes...ah?" Kong Yue subconsciously responded, but as soon as he opened his mouth, he realized something was wrong. He quickly raised his head and said in shock: "Brother, you want to go to the typhoid fever patients? There are all typhoid fever and plague patients there. , what should I do if my eldest brother catches the cold?"

Taiping Road gathered together patients infected with the typhoid plague to try to prevent the source of infection from spreading.

Because the talisman water was given to cure the plague, these typhoid plague patients did not resist, but cooperated very well. Otherwise, they would be 'disbelievers' and they would have to wait to die.

Those who have not been infected with the typhoid plague must not dare to go near there, unless they are some people who have drank the talisman water and survived the typhoid plague, and they dare to go in and out at will. In the eyes of these people, they have been protected by the great sage and mentor. Not afraid of this little plague at all!
  Lu Yu's request caught Kong Yue by surprise, and he couldn't understand why his eldest brother would go to such a dangerous place.

"I made a medicine that may be effective against typhoid plague." Lu Yu thought for a while and said, "So I want to give it a try."

"Then, just leave it to someone else!" Kong Yue was stunned for a moment, then shook his head, firmly opposed to Lu Yu taking the risk.

At this moment, someone outside the house came to report.

"Deacon Tang sent someone over to deliver the letter!"

"Let him come over." Lu Yu nodded.

Soon a tall and tall young man walked in.

This is Tang Shigui's personal guard. Lu Yu has some impression of him. His name is Fan Yun.

"Deacon Lu!" Fan Yun saluted seriously.

"Brother Tang asked you to come over, why?" Lu Yu asked.

"Young Master has been busy doing business these days and accidentally contracted typhoid fever..." Fan Yun said in a low tone: "So, Young Master said that the business cooperation with you may have to be delayed a little. This is the Young Master's letter. …”

He was originally a slave of the Tang family. After he became Tang Shigui's personal guard, Tang Shigui relieved him of his status as a domestic slave. Because he was grateful, he was loyal to Tang Shigui, so his mood at this moment was naturally very heavy.

Lu Yu frowned. He really didn't expect that Tang Shigui was infected with the typhoid plague!

"Take me there!" Lu Yu took the letter, looked at it briefly, then raised his head and said.

Fan Yun was stunned, but nodded: "Yes!"

(End of this chapter)

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