Lin Gao Qiming
Chapter 344 Production of Pharmaceutical Factory
Chapter 344 Production of Pharmaceutical Factory
When Huang Dashan was trial-producing sweet potato kvass, Shi Yanren was cleaning the bottles in the pharmaceutical factory—the glass bottles that had been applied to the Planning Commission for a long time were shipped in this time, most of them were produced by the glass factory, and some were recycled and sterilized.Thousands of bottles, large and small, were placed in rattan baskets, filling the entire yard of the pharmaceutical factory.The bottle size ranges from 500ml for normal saline to small vials.
So the people in the entire pharmaceutical factory cleaned the bottles for most of the day.The cleaned bottles are pushed into the steam room for high-temperature steam sterilization-this is currently the most effective large-scale disinfection method in pharmaceutical factories.
With these bottles, pharmaceutical factories can officially produce finished products—otherwise there would be no place to store the products.Zhao Yanmei set up a still room with all glass equipment, which is not only used to distill medical distilled water, but also used to make Chinese herbal medicine extracts, which are used as injections.
Shi Yanren stared at this not-too-complicated but large-scale distillation facility, marveling at the rapid progress of the glass factory, with such a complex shape, a large number of thick and thin pipes, multi-passes, and valves.The alcohol lamp for heating is flickering with a faint blue flame. There are many yellow and white plant flowers in the evaporating dish. The liquid is slightly bubbling. The steam passes through the pipe and passes through the condenser of the serpentine glass tube. Collect in bottle.
The whole scene looks weird, neither science fiction nor fantasy, but like a mad scientist's underground laboratory in a low-budget movie.
"What is this doing?"
"The distilled extract is honeysuckle, a medicine for heatstroke prevention, and it is specially used to treat summer heat and cold. Liu San said that this can be used as a base liquid to make Shuanghuanglian preparations." Hu Yicheng is in charge of the distillery today, and there is no need to go to the underground bacteria room for cultivation. more pleasant.
"Is this safe?" He murmured. The composition of traditional Chinese medicine injections is unknown, and there are many impurities. If it is injected into the human body like this, there is no way to rescue it if there is an allergic reaction.
Hu Yicheng saw what he was thinking, "The concentrated solution for oral consumption will cause diarrhea at most, and it will never kill you."
"I'm worried because I feel hung up." Shi Yanren sighed.
"After distilling this batch, I'm going to make Bupleurum injection. It's less difficult. Liu San spent a lot of sun in the yard. It's very effective for summer heat and cold."
"But this equipment is a little less efficient."
Liu San came out from the inside: "I have already ordered another set. It will be made in a glass factory. This time, I will use steam for heating. It is much more efficient than this burning alcohol lamp, and the temperature is also easy to control. Minister, come to my room." Sit down."
As he spoke, he took him into his own traditional Chinese medicine pharmaceutical workshop.
This workshop is actually a large room of about 16 square meters, with a high ceiling.Crock pots on a row of stoves are boiling Chinese medicine. On the operating table, there are guillotines for cutting medicine, mortars of various materials, and [-] tael scales for Chinese medicine... You have seen it all the time. There are piles of unseen equipment everywhere, some brought by Liu San himself, and some custom-made here.
Shi Yanren sniffed the smell of medicine in the air, found a stool and sat down,
"Here are some medicines I made myself." Liu San enthusiastically showed him a row of cardboard boxes and small porcelain bottles on the table.
"This is Zhixue powder," Liu San picked up a small porcelain bottle, "It's made of big thistle, it can cool blood and stop bleeding: it's used for hemorrhagic diseases caused by excessive blood heat, such as vomiting blood, epistaxis, metrorrhagia, hematuria, etc. Dispersing blood stasis, detoxifying and eliminating carbuncle: used for pyretic carbuncle, taken orally or applied externally..."
"That's enough, that's enough, you don't need to memorize your traditional Chinese medicine medical books." Shi Yuren glanced suspiciously, he knew that Chinese medicine has a characteristic, and almost every kind of medicinal material can list a lot of "for a certain medicine" A certain symptom is effective", in fact, rarely can really play a key role, "does it work?"
"Of course it works. If you are bleeding in the wild, immediately find a large thistle decoction and take it orally. It will take effect immediately. Crushing it and applying it externally can also stop the bleeding."
Shi Yuren thought that there might be some ingredients in it that could reduce the clotting time, but he could organize research and research—there will be a lot of demand for hemostatic drugs in future military battles.
"Also: Tincture soaked in ethanol can lower blood pressure and inhibit human tuberculosis bacilli."
"sounds good."
"This is Weiyan Pill, which treats stomach pain, pantothenic acid, gastric ulcer and duodenal ulcer. The main ingredient is cuttlefish bone. I got it from a seafood processing factory. It can also be used as a hemostatic medicine, which is very effective in treating knife wounds. .
"This is Zhudan Wan." Liu San said, "There are many indications, but I know that you are not interested in these, Dean, but there is one purpose that you must find useful."
"Oh? What."
"Cough relief." Liu San said, "The cough relief effect of pig bile powder has been tested pharmacologically. It can also cure night blindness."
"Lauda tincture." Liu San took out another bottle with a danger mark on it. "It can be used for cough relief, diarrhea relief, and pain relief."
"What about addiction?"
Liu San spread out his hands: "It's hard to say, animal experiments are required. However, I have studied it with Director Zhao and Xiao Hu, and I have also read medical books, and I did it completely according to the requirements of the Pharmacopoeia. It will not be too harmful. It’s big, just control the use.”
"Don't make it into a universal drug." Shi Yanren instructed, "Divide it into three varieties. It is best to make tablets for antidiarrheal and painkillers-easy to take, and make syrup for cough medicine. No matter what kind of medicine, While ensuring the curative effect, it is necessary to keep the ingredients of opium as small as possible to avoid addiction.”
Although opium addiction is not as severe as modern hard drugs, it is also very troublesome to quit addiction.
"Okay, let's change the formula." Liu San wrote down his request casually.He took out another small wooden box and opened it mysteriously: "Doctor Shi, try it?"
Shi Yanren looked at it, and there was a kind of half-withered leaf in the box, curled into balls.
"Betel nut?" He picked up one and stuffed it into his mouth.Very bitter.
"It's coca leaves."
"Hmm..." Shi Yanren almost didn't spit it out on the spot.
"Don't worry, you won't be addicted." Liu San laughed narrowly, "Or at most it is as addictive as betel nut."
Of course Shi Youren knew that in South America, chewing coca leaves could be regarded as a "ethnic habit".The Indians used it to refresh the mind, eliminate fatigue, and increase strength; it was also used to keep out the cold, cure diseases, and relieve discomfort caused by stomach cramps, rheumatism, and headaches.It's a popular pastime.
"These are the leaves picked from the coca trees on the farm. The trees are too small, so only a small amount is picked. Each person shares a little." Liu San said, "After the production increases, we can pick a lot."
"What's the point of wanting this thing?"
"Coca leaves can also be used to make medicine." Liu San said, "It would not be better to use this instead of cigarettes as a recreational product for the army and laborers."
"This—" Shi Yanren thought this was too awesome.However, coca leaves do have a strong effect of invigorating the spirits, and they are indeed useful to the army and laborers.Not very addictive though.
"Amphetamine was prepared by the Yankees for soldiers in the Third World War. There are more people in the world than us. Coca leaves are not as poisonous as amphetamine." He took out another bottle from behind him.Poured a cup full of dark drink for Shi Yanren, "Drink and watch."
"What is this?" Shi Yanren suddenly became vigilant.
"Cola."
"Coke? These things are so rare now." Shi Yanren glanced suspiciously, took a sip, and it really tasted like cola, a bit sweeter, but it was lifeless—like a cola that had run out of gas after being put for a long time.
"You deserve it yourself?"
"Yes, distillate of coca leaves is added in it." Seeing that Shi Yanren was going to have a seizure, Liu San quickly added, "Very little. It can be almost ignored. As long as there is baking soda, we can start producing Coke .”
It's really strange: Shi Youren thought to himself, the soda didn't work out, but both Kvass and Coke came out.He decided not to pester him anymore, lest there be any weird things that would make him a guinea pig.ask:
"How is the extraction of willow bark that I mentioned last time?"
Willow bark has been an antipyretic and analgesic commonly used in Europe and Asia since ancient times, and its active ingredient is salicylic acid.The modern drug aspirin was born based on the analysis of this drug.
Aspirin was chemically synthesized, and it was still too early for the traveler's chemical level, but it was not difficult to extract the active ingredients from willow bark, and it could also play a certain role.
"I'm doing it, and I've extracted some. But there are not many willows here." Liu San said.
"We can make Wu Nanhai grow more by the river. It can be used as a decoration for the scenery and as a raw material." Shi Youren knew that there are very few effective medicinal ingredients contained in willow bark and willow leaves, and the extraction effect is limited, but Aspirin is a very useful analgesic and antipyretic, as well as anticoagulant and antirheumatic effects.It is the best panacea at this stage.
Liu San said: "I have a request, I hope the minister will go to the executive committee to talk about it."
"Oh, what do you want."
"Buy the raw medicine shop in the county."
"Runshitang?" Shi Yuren knew that Liu San often went to this pharmacy to buy medicines, process medicinal materials and so on, and he had a happy cooperation with the other party, "Isn't it a good cooperation between you two."
"Shopkeeper Yang's ideas are not bad, and it's safe to entrust them to do things. But I'm not the boss, and it's inconvenient to decide many things. It's a waste of a few professionals in it." He poured himself a glass of "Coke", "In addition, the raw medicine shop Its foundation is too weak, and it can't even go to the medicine market, and it never enters the precious medicinal materials. It is too weak as a partner. It has to be transfused. I originally wanted to inject capital myself, but I have no money..."
"Let the executive committee buy it, and then you will be the shopkeeper?"
"I don't want to be the shopkeeper—it's enough to be the boss and guide them how to do it. The shopkeeper Yang in it doesn't have much experience, but he is eager to learn. He is a man who can be made."
(End of this chapter)
When Huang Dashan was trial-producing sweet potato kvass, Shi Yanren was cleaning the bottles in the pharmaceutical factory—the glass bottles that had been applied to the Planning Commission for a long time were shipped in this time, most of them were produced by the glass factory, and some were recycled and sterilized.Thousands of bottles, large and small, were placed in rattan baskets, filling the entire yard of the pharmaceutical factory.The bottle size ranges from 500ml for normal saline to small vials.
So the people in the entire pharmaceutical factory cleaned the bottles for most of the day.The cleaned bottles are pushed into the steam room for high-temperature steam sterilization-this is currently the most effective large-scale disinfection method in pharmaceutical factories.
With these bottles, pharmaceutical factories can officially produce finished products—otherwise there would be no place to store the products.Zhao Yanmei set up a still room with all glass equipment, which is not only used to distill medical distilled water, but also used to make Chinese herbal medicine extracts, which are used as injections.
Shi Yanren stared at this not-too-complicated but large-scale distillation facility, marveling at the rapid progress of the glass factory, with such a complex shape, a large number of thick and thin pipes, multi-passes, and valves.The alcohol lamp for heating is flickering with a faint blue flame. There are many yellow and white plant flowers in the evaporating dish. The liquid is slightly bubbling. The steam passes through the pipe and passes through the condenser of the serpentine glass tube. Collect in bottle.
The whole scene looks weird, neither science fiction nor fantasy, but like a mad scientist's underground laboratory in a low-budget movie.
"What is this doing?"
"The distilled extract is honeysuckle, a medicine for heatstroke prevention, and it is specially used to treat summer heat and cold. Liu San said that this can be used as a base liquid to make Shuanghuanglian preparations." Hu Yicheng is in charge of the distillery today, and there is no need to go to the underground bacteria room for cultivation. more pleasant.
"Is this safe?" He murmured. The composition of traditional Chinese medicine injections is unknown, and there are many impurities. If it is injected into the human body like this, there is no way to rescue it if there is an allergic reaction.
Hu Yicheng saw what he was thinking, "The concentrated solution for oral consumption will cause diarrhea at most, and it will never kill you."
"I'm worried because I feel hung up." Shi Yanren sighed.
"After distilling this batch, I'm going to make Bupleurum injection. It's less difficult. Liu San spent a lot of sun in the yard. It's very effective for summer heat and cold."
"But this equipment is a little less efficient."
Liu San came out from the inside: "I have already ordered another set. It will be made in a glass factory. This time, I will use steam for heating. It is much more efficient than this burning alcohol lamp, and the temperature is also easy to control. Minister, come to my room." Sit down."
As he spoke, he took him into his own traditional Chinese medicine pharmaceutical workshop.
This workshop is actually a large room of about 16 square meters, with a high ceiling.Crock pots on a row of stoves are boiling Chinese medicine. On the operating table, there are guillotines for cutting medicine, mortars of various materials, and [-] tael scales for Chinese medicine... You have seen it all the time. There are piles of unseen equipment everywhere, some brought by Liu San himself, and some custom-made here.
Shi Yanren sniffed the smell of medicine in the air, found a stool and sat down,
"Here are some medicines I made myself." Liu San enthusiastically showed him a row of cardboard boxes and small porcelain bottles on the table.
"This is Zhixue powder," Liu San picked up a small porcelain bottle, "It's made of big thistle, it can cool blood and stop bleeding: it's used for hemorrhagic diseases caused by excessive blood heat, such as vomiting blood, epistaxis, metrorrhagia, hematuria, etc. Dispersing blood stasis, detoxifying and eliminating carbuncle: used for pyretic carbuncle, taken orally or applied externally..."
"That's enough, that's enough, you don't need to memorize your traditional Chinese medicine medical books." Shi Yuren glanced suspiciously, he knew that Chinese medicine has a characteristic, and almost every kind of medicinal material can list a lot of "for a certain medicine" A certain symptom is effective", in fact, rarely can really play a key role, "does it work?"
"Of course it works. If you are bleeding in the wild, immediately find a large thistle decoction and take it orally. It will take effect immediately. Crushing it and applying it externally can also stop the bleeding."
Shi Yuren thought that there might be some ingredients in it that could reduce the clotting time, but he could organize research and research—there will be a lot of demand for hemostatic drugs in future military battles.
"Also: Tincture soaked in ethanol can lower blood pressure and inhibit human tuberculosis bacilli."
"sounds good."
"This is Weiyan Pill, which treats stomach pain, pantothenic acid, gastric ulcer and duodenal ulcer. The main ingredient is cuttlefish bone. I got it from a seafood processing factory. It can also be used as a hemostatic medicine, which is very effective in treating knife wounds. .
"This is Zhudan Wan." Liu San said, "There are many indications, but I know that you are not interested in these, Dean, but there is one purpose that you must find useful."
"Oh? What."
"Cough relief." Liu San said, "The cough relief effect of pig bile powder has been tested pharmacologically. It can also cure night blindness."
"Lauda tincture." Liu San took out another bottle with a danger mark on it. "It can be used for cough relief, diarrhea relief, and pain relief."
"What about addiction?"
Liu San spread out his hands: "It's hard to say, animal experiments are required. However, I have studied it with Director Zhao and Xiao Hu, and I have also read medical books, and I did it completely according to the requirements of the Pharmacopoeia. It will not be too harmful. It’s big, just control the use.”
"Don't make it into a universal drug." Shi Yanren instructed, "Divide it into three varieties. It is best to make tablets for antidiarrheal and painkillers-easy to take, and make syrup for cough medicine. No matter what kind of medicine, While ensuring the curative effect, it is necessary to keep the ingredients of opium as small as possible to avoid addiction.”
Although opium addiction is not as severe as modern hard drugs, it is also very troublesome to quit addiction.
"Okay, let's change the formula." Liu San wrote down his request casually.He took out another small wooden box and opened it mysteriously: "Doctor Shi, try it?"
Shi Yanren looked at it, and there was a kind of half-withered leaf in the box, curled into balls.
"Betel nut?" He picked up one and stuffed it into his mouth.Very bitter.
"It's coca leaves."
"Hmm..." Shi Yanren almost didn't spit it out on the spot.
"Don't worry, you won't be addicted." Liu San laughed narrowly, "Or at most it is as addictive as betel nut."
Of course Shi Youren knew that in South America, chewing coca leaves could be regarded as a "ethnic habit".The Indians used it to refresh the mind, eliminate fatigue, and increase strength; it was also used to keep out the cold, cure diseases, and relieve discomfort caused by stomach cramps, rheumatism, and headaches.It's a popular pastime.
"These are the leaves picked from the coca trees on the farm. The trees are too small, so only a small amount is picked. Each person shares a little." Liu San said, "After the production increases, we can pick a lot."
"What's the point of wanting this thing?"
"Coca leaves can also be used to make medicine." Liu San said, "It would not be better to use this instead of cigarettes as a recreational product for the army and laborers."
"This—" Shi Yanren thought this was too awesome.However, coca leaves do have a strong effect of invigorating the spirits, and they are indeed useful to the army and laborers.Not very addictive though.
"Amphetamine was prepared by the Yankees for soldiers in the Third World War. There are more people in the world than us. Coca leaves are not as poisonous as amphetamine." He took out another bottle from behind him.Poured a cup full of dark drink for Shi Yanren, "Drink and watch."
"What is this?" Shi Yanren suddenly became vigilant.
"Cola."
"Coke? These things are so rare now." Shi Yanren glanced suspiciously, took a sip, and it really tasted like cola, a bit sweeter, but it was lifeless—like a cola that had run out of gas after being put for a long time.
"You deserve it yourself?"
"Yes, distillate of coca leaves is added in it." Seeing that Shi Yanren was going to have a seizure, Liu San quickly added, "Very little. It can be almost ignored. As long as there is baking soda, we can start producing Coke .”
It's really strange: Shi Youren thought to himself, the soda didn't work out, but both Kvass and Coke came out.He decided not to pester him anymore, lest there be any weird things that would make him a guinea pig.ask:
"How is the extraction of willow bark that I mentioned last time?"
Willow bark has been an antipyretic and analgesic commonly used in Europe and Asia since ancient times, and its active ingredient is salicylic acid.The modern drug aspirin was born based on the analysis of this drug.
Aspirin was chemically synthesized, and it was still too early for the traveler's chemical level, but it was not difficult to extract the active ingredients from willow bark, and it could also play a certain role.
"I'm doing it, and I've extracted some. But there are not many willows here." Liu San said.
"We can make Wu Nanhai grow more by the river. It can be used as a decoration for the scenery and as a raw material." Shi Youren knew that there are very few effective medicinal ingredients contained in willow bark and willow leaves, and the extraction effect is limited, but Aspirin is a very useful analgesic and antipyretic, as well as anticoagulant and antirheumatic effects.It is the best panacea at this stage.
Liu San said: "I have a request, I hope the minister will go to the executive committee to talk about it."
"Oh, what do you want."
"Buy the raw medicine shop in the county."
"Runshitang?" Shi Yuren knew that Liu San often went to this pharmacy to buy medicines, process medicinal materials and so on, and he had a happy cooperation with the other party, "Isn't it a good cooperation between you two."
"Shopkeeper Yang's ideas are not bad, and it's safe to entrust them to do things. But I'm not the boss, and it's inconvenient to decide many things. It's a waste of a few professionals in it." He poured himself a glass of "Coke", "In addition, the raw medicine shop Its foundation is too weak, and it can't even go to the medicine market, and it never enters the precious medicinal materials. It is too weak as a partner. It has to be transfused. I originally wanted to inject capital myself, but I have no money..."
"Let the executive committee buy it, and then you will be the shopkeeper?"
"I don't want to be the shopkeeper—it's enough to be the boss and guide them how to do it. The shopkeeper Yang in it doesn't have much experience, but he is eager to learn. He is a man who can be made."
(End of this chapter)
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