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Chapter 146 It is not advisable to eat fruit before and after taking medicine

Chapter 146 It is not advisable to eat fruit before and after taking medicine

It is best for patients not to eat fruit half an hour before and after taking the medicine, because some fruits contain substances that can chemically react with the medicine, reducing the efficacy of the medicine.Certain fruits contain a kind of tannin component, which exists more in green fruits, such as unripe persimmons, apples, apricots and so on.Although this ingredient is a natural plant ingredient, it is easy to chemically react with the drug, causing the drug to accumulate and precipitate in the body, and the solubility becomes smaller, thereby reducing the efficacy of the drug.

Most fruits contain citric acid and malic acid, which will change the pH value in the intestinal tract and indirectly affect the action of drugs.Drugs that are sensitive to pH, such as oral penicillins, will affect the efficacy of the drug when taken together with more acidic fruits (such as hawthorn, grapes, etc.).

Fruits generally contain metal ions such as calcium and magnesium. These components can have a comprehensive reaction with certain types of drugs (such as tetracyclines) to form insoluble complexes, which hinder the absorption of drugs in the body.The commonly used blood lipid-lowering drugs, antibiotics, sleeping pills, anti-allergic drugs, etc., may interact with the substances in the fruit, making the drugs ineffective or producing toxic and side effects.For example, some antiallergic drugs may react with grapefruit and citrus fruits, causing arrhythmia and even fatal ventricular fibrillation.Patients with allergic rhinitis may die of poisoning if they drink grapefruit (also known as Huyou) juice while taking antiallergic drugs (terfenadine).

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When treating insomnia, one sleeping pill cannot be used continuously to prevent drug resistance or addiction.In addition, most sleeping pills are detoxified by the liver and excreted by the kidneys.Often take sleeping pills, liver and kidney function should be checked regularly.

(End of this chapter)

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