Abuse the Heroine To Be a School Tyrant

For example, CTX001 is being developed for the treatment of sickle cell disease and beta thalassemia, such as gene therapy with a single dose of ARCUS nuclease AAV vector targeting PCSK9, which can lead to long-term reduction of serum PCSK9 and LDL cholesterol in rhesus monkeys, and German Researchers at the University of Texas Southwestern Medical Center used CRISPR gene editing to treat Duchenne muscular dystrophy (DMD) in dogs…

Gene editing is already another huge advance in the magic of modern medicine! However, it is not completely harmless, nor is it fully mature.

She looked at her document and wrote a few words: "New Gene Therapy - The Solution to Avoiding Immune Responses."

If this manuscript were to be seen by 21st century scientists who study genes, it is estimated that their jaws would drop.

Because the recent "Nature" has published articles against gene editing, to be precise, it is vigilant against gene editing medical treatment.

Their argument is that Cas9 antibodies are ubiquitous in the human body. If CIRSPR-Cas9 is used for treatment, its therapeutic effect may not be as good as people expect, and it may even trigger a violent immune response in the human body.

When it comes to gene editing, we have to talk about how Cas9 works.

CRISPR-Cas9 is a primitive immune system. The gene editing system relies on an enzyme called Cas9. Scientists use RNA-guided Cas9 nuclease to cut and modify specific genomic sites in a variety of cells. It can thus be used to treat diseases with certain genetic mutations.

But the dissenting article took 30 cord blood and 15 healthy adult blood for analysis.

In cord blood, 79% had SaCas9 antibodies; 65% had SpCas9 antibodies. In healthy human blood, 71% also have SaCas9 antibodies. This also means: In the human body, the natural immune system will greatly reduce the effect of CRISPR-Cas9 gene therapy.

And Xu Jingyi's article is to propose a solution that can avoid triggering an immune response.

This is also the best solution tested for centuries, a therapy based on engineered autologous hematopoietic stem cells, chimeric antigen receptor K cells (CAR-K), to avoid immune responses.

Xu Jingyi tapped articles sleeplessly in the lab.

In the outside world, the public opinion raised by the Saudi royal family not only did not stop, but it was on the wind and waves because of another incident.

"C City Evening News" is brightly lit, and the editors are busy editing manuscripts for a day.

Editor-in-chief Liu Chen was lying on the sofa, picking from left to right, happily worrying about tomorrow's headlines.

Since the rise of Xingyao Company, they have never worried about news sources and sales. As long as it is a topic related to Xingyao, it can be sold out of stock.

For example, this time, whether to put the National Day mechanical rabbit first, or whether the Saudi royal family praised slime as the top card, which of these two news is heavy enough. Both are related to Shining Star Company.

What a blissful trouble.

Confused, Liu Chen decided to browse the official website of Xingyao Company to see the wind direction.

At this moment, a very excited voice rushed in with the sound of running. "Coax!" The glass door was knocked in by the other party.

The voice was so loud that it frightened Liu Chen.

"Editor-in-chief! Big news! Really big news!"

The young face rushed in holding the iPad, his hair was flowing into the sea, and he was very excited.

"Calm down! Don't be a reporter!" Liu Chen reprimanded with a stern face, straightened the bangs on his head, and then looked at him, "What breaking news is there about Xingyao Company? "

As he said that, Liu Chen opened the official website of Xingyao Company and took a look, but there were no new headlines.

The intern reporter who rushed in was Wei Wenxi.

He is a graduate student led by Zhu Hao. Since Professor Zhu Hao's reputation was ruined, Wei Wenxi has been in the research institute for a few days, and he ran out of the ivory tower to find a job after realizing that there was no way out.

Perhaps when he was chatting with the interviewer, he said a few topics related to Xu Jingyi, and he was inexplicably transferred from the administrative position he was applying for to the reporter department.

It is the social news section that is in charge, and the focus of the docking is Xingyao and other companies.

The explanation given above is that Wei Wenxi was originally a graduate student in biochemistry and had enough professional knowledge to handle interviews and reports in this area very well without making simple mistakes.

But Wei Wenxi's complexion guessed, it is estimated that he and Xu Jingyi's classmates even had a chat experience to get such an opportunity.

He could really feel the true meaning of the sentence that one person attains the truth.

"There is no breaking news on the official website of Xingyao Company, but there is breaking news about the Nobel Prize!" Wei Wenxi still handed the ipad excitedly.

Liu Chen looked indifferent, and his body softened from sitting upright: "Oh. What's the news? Which award-winning drug addict? Is he still in jail? Could it be that there is a bribery transaction scandal?"

Wei Wenxi's face was embarrassed, did the editor-in-chief read too much in the social section! That's a Nobel Prize! Not showbiz awards.

He shook his head quickly: "No! The Nobel Peace Prize has been nominated jointly by Xu Jingyi and the Saudi royal family! There is also a separate nomination for Xu Jingyi for the Nobel Prize in Physics."

"What!" Liu Chen's calm expression was gone, he stood up abruptly, and put his hands on the table tightly, "Do you say it again? Did you nominate Xu Jingyi for the Nobel Prize? Nominated for two at the same time? Are you sure? "

As for the Saudi royal family, he has long forgotten it.

"It's true!" Seeing Liu Chen's excitement, Wei Wenxi calmed down and handed the iPad to Liu Chen, "Look, editor-in-chief! Some foreign media has already published it!"

Liu Chen looked down the ipad. This is the home page of "Lulushe". According to the Norwegian state media NRK, since Prince Faisas announced that he would share the desert control technology of slime with the world, two Norwegians Councillors nominated Xu Jingyi and Prince Faisas as candidates for the Nobel Peace Prize. And for the first time, two other Norwegian parliamentarians nominated Xu Jingyi as a candidate for the Nobel Prize in Physics. Such double nominations are rare for Nobel Prizes.

"It's actually true!" Liu Chen clenched his fists, his face flushed, "My God! This, this is shocking to me... Hurry up and take a look. Have any other official media released news?"

Wei Wenxi immediately said: "I searched before I came. There must have been none ten minutes ago."

"Okay!" Liu Chen clapped his hands, "Then what are you doing? Hurry up and write a report based on this news."

"Ah? You still need to write this?" Wei Wenxi showed a cute expression, "Isn't it a direct quote?"

Seeing Wei Wenxi's surprised appearance, Liu Chen shook his head: "This is our own family, and being able to be nominated at the same time is also a matter of honor for the country. What's the point of readers reading a dry sentence? Write it! Hurry up and go. , if you write it well, tomorrow's front page headline will be yours! Don't write it if you don't want the front page!"

"I write, I write!" Wei Wen responded quickly. If it can be on the front page headlines, it will basically be a positive thing.

Seeing Liu Chen staring at him impatiently again, he immediately turned around and ran out.

Liu Chen slowly slid back to the sofa, um, it seems that tomorrow's headlines will be settled, don't worry, it's good.

Wei Wenxi wrote the report very quickly, and cited foreign media reports as evidence. As soon as it was freshly released, it was like water that fell into a frying pan and exploded in an instant!

There was a lot of uproar on the forum related to Shining Star Company.

[Xiao Yanzi: I thought it was an act against the sky to cooperate with the Saudi royal family, but I didn’t expect that it was not the most awesome, only more awesome! Damn, was nominated for two Nobel Prizes at the same time! What do you do when you get the trophy? One to hold and one to throw away? 】

[Lin Lan Yinfeng: Are you going to laugh at me upstairs? ! But it's no surprise to be nominated! It's true, awesome, dragon absorbing water, slime! Now the dragon water absorption in City G has stopped. Have you seen the water quality monitoring report? Not too good! Ahhh! When will slime come to our county! Help! 】

[Dirty Pear 66666: Slime Rise! My country is about to rise! Humph, just wait for the foreigner to come over and ask for cooperation, hahaha! When will Xingyao come out with a few more flying cars and the like to turn over foreign capitalists! 】

[Jun Chonglang: ...Although I am also very happy. But upstairs...Huaguo has made headway in the field of research and development of automobiles. I'm afraid that the first to sacrifice to the sky will be Huaguo enterprises. 】

[Tudou: Can the above one not be crooked, with rhythm! I was thinking how effective slime is! Will desert nature reserves be formed in the future? Hahaha... It is everyone's responsibility to protect rare scenic spots! 】

...

Netizens leave messages very quickly, and the media are not slow to track reports.

For example, the relatively wealthy media are no longer limited to reporting on fried rice. They directly dispatch Saudi resident reporters to interview Prince Faisas and interview the Nobel Prize resident.

"Excuse me, His Royal Highness Prince Faisas! Do you know that you and Ms. Xu Jingyi have been nominated for the Nobel Prize for the Peace Prize?"

After the press conference, the Penguin reporter couldn't help but rushed over with the microphone.

Looking at the Chinese characters, Faisas' arrogant expression disappeared, replaced by a gentle smile: "That is natural. I am proud to be nominated together with Ms. Xu Jingyi."

The penguin reporter's waist became more straight, and a strong sense of pride emerged in his heart.

She continued to ask: "Prince Faisas. We all know that slimes are environmentally friendly robots. How much can it achieve in terms of environmental modification? What is your expectation?"

The smile on Feisas's face was even bigger: "Slime is a seriously underestimated invention. The specific source code is hard to say at present, but it is certain that the water resources decomposed by slime after processing the garbage are completely acceptable. Comparable to the existence of pure water, slime has a protective mechanism for plant roots and organisms. For example, after decomposing the water, it will spread around the plant roots for the first time."

"Sir, do you mean that slimes can spray water accurately?" Penguin reporter asked in surprise.

——Precision seeding and watering is nothing in the land of fish and water, but for relatively arid provinces, this technology can save a lot of water resources.

"Yes!" Faisas nodded, then blinked, "Slime is the greatest invention I have ever seen, and it is closely related to our people's livelihood. I believe that our excellent scientists can work with Ms. Xu Jingyi to develop more Robots suitable for environmental modification.”

The words of Fessas immediately caught the eyes of the Penguin reporter, and the title was ready in his mind: "Prince Fessas concludes that the greatest invention of the 21st century Slime! "Prince of the royal family speaks with a political inclination, and every word spoken in public is thoughtful.

One sentence floated in the minds of all reporters: Saudi Arabia is surrendering to China.

Suddenly, a black reporter said excitedly: "His Royal Highness Prince Feisas! Excuse me, is the sharing of slime technology really free?"

Looking at his lean body and dark skin, and looking at the logo on his microphone, you can tell that this is from a relatively dry and barren land on the African continent.

The people over there have serious pollution problems even when they drink water. It is not difficult to understand why he would be so excited.

"Yes.\" Prince Feisas was not so enthusiastic about people from other countries, he simply nodded, and then introduced the functions of slimes to other reporters. The key point of his words is to praise Xu Jingyi's greatness, and even the Nobel Prize owes all the credit to Xu Jingyi. The whole person was extremely low-key.