Doctor’s Life Simulator
Chapter 361: simulation! Detailed side effects of Pfizer's smoking cessation pills
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Looking at this award, Qin Lang was also a little overjoyed. It turned out to be a research project with the potential of the Nobel Prize in Medicine.
The Nobel Prize in Physiology or Medicine, one of the five Nobel Prizes established in accordance with Nobel's will, is designed to honor people who have made important discoveries or inventions in the field of physiology or medicine.
Since the Nobel Prize in Physiology or Medicine was awarded for the first time in 1901, only in 1935, Wu Liandecheng, a pioneer of modern medicine in China, became the first Chinese to be nominated for the award. It was not until 2015 that Tu Youyou won the first Nobel Prize in China. Physiology or Medicine Award.
The Nobel Prize winners are often announced in October each year, and the award ceremony is held in Stockholm, Sweden, on the anniversary of Munobel's death every year, and is awarded by the King of Sweden in person.
This award is generally regarded as the highest honor that can be achieved in the field of physiology or medicine!
Once he can win the Nobel Prize, he will undoubtedly go down in history and become a top leader in the medical field.
Rao is the state of mind that Qin Lang has simulated for several generations, and there are huge waves.
Such an opportunity is in front of us, and Qin Lang certainly will not let it go.
Moreover, through this task, Qin Lang also speculated on the real cause of this patient, which seems to be inextricably related to the side effects of Pfizer's smoking cessation drugs.
Qin Lang lifted his spirits and suggested to Director Zhu and Director Qing:
"Director Zhu, Director Qing, I have an immature suggestion. Perhaps, the patient really has a cardiac infarction as determined by Director Qing, but he is not a common ST-segment elevation myocardial infarction."
Hearing Qin Lang's words, Director Qing and Director Zhu on the side were a little surprised, especially Director Zhu, who now attaches great importance to Qin Lang's suggestion, and immediately asked, "Director Qin, please be specific?"
Regarding Director Zhu's attitude, Director Qing also looked at this young man. Could it be that he really has a unique opinion?
Qin Lang explained unhurriedly:
"It's like this. When I was in the Second Hospital of Harbin Medical University, I exchanged some cases with Professor Liu. I happened to meet a similar patient. Conventional coronary angiography is indeed the gold standard for diagnosing coronary heart disease, but there are still Some special patients are easily missed by simple coronary angiography."
Hearing the experience and experience of Professor Liu from the Second Hospital of Harbin Medical University, Director Zhu and Director Qing both looked solemn. In their opinion, Professor Liu from the Second Hospital of Harbin Medical University is a ceiling-level figure in the cardiovascular field. He has said so, and it must not be wrong.
The two directors were envious for a while. Qin Lang was able to communicate and study with Professor Liu in person. The two chief directors calmed down and analyzed Qin Lang in the body slowly.
"In daily practice, myocardial infarction is missed, and the reason is that the occlusion of the coronary artery in patients with non-ST-segment elevation myocardial infarction is located in the distal end, and the affected myocardial area is limited to the lateral or posterior wall, which is not easy to detect. ."
"The pathogenesis of patients with non-ST-segment elevation myocardial infarction is mainly due to myocardial oxygen consumption or oxygen supply imbalance. In addition to the increase in cardiac oxygen consumption, it may also be due to plaque rupture or myocardial microcirculation embolism after the attachment of thrombus on the plaque surface. At this time, coronary angiography showed that the blood flow in the epicardial coronary artery was smooth, so the examination could not find any abnormality.”
Listening to Qin Lang's introduction, the two chief directors nodded again and again, quite rewarding.
Director Qing looked at Qin Lang, who was talking eloquently, with a hint of appreciation in his heart, such a young talent.
Sure enough, the growth of a top doctor, talent, guidance from famous teachers, and support from nobles are indispensable.
"Then, if Director Qin really judges whether the patient is of ST-elevation myocardial infarction as you do, how are you going to detect these atypical myocardial infarctions?"
Director Zhu asked very curiously, which was also a new knowledge point for him.
Looking at Qin Lang, Director Zhu had the feeling that he followed his teacher back then.
Qin Lang immediately took out the new assistive technology mastered in the simulated world and shared it with Director Zhu and Director Qing:
"The method is called Holter, and it is checked using t Holter and Holter software analysis..."
After listening to Qin Lang's introduction, Director Zhu's eyes also brightened. This is really a brand new method.
Director Zhu rubbed his hands: "then Director Qin, let's try it now."
"it is good!"
Qin Lang immediately took the two directors to start a dynamic electrocardiogram examination. Half an hour later, as Qin Lang had guessed, he got the test results. The patient was really a very rare and hidden myocardial infarction.
After the diagnosis, Director Zhu and Director Qing immediately felt relieved, they were too experienced in the treatment of myocardial infarction.
Director Zhu immediately treated the patient, including anti-ischemic therapy, anti-thrombotic therapy, and interventional therapy according to the patient's risk stratification.
When Director Zhu carried out the treatment step by step, Director Qing also left the ward in admiration, and he really admired Qin Lang.
However, what puzzled him was, what was the cause of the myocardial infarction in the patient?
The same problem also troubled Director Zhu, but as long as the patient could be brought back from the death line, Director Zhu was very fortunate.
As for what caused it, he could only ask for no further explanation.
This kind of situation is very common in clinical practice. For many patients and many diseases, the real cause cannot be traced back. The human body is really an overly complex and mysterious system.
Under Director Zhu's treatment, Xie Fei's condition was finally brought under control.
In the ward, Director Zhu also explained to Xie Fei with a solemn expression:
"Xie Fei, this time, you have to thank Director Qin for giving you a dynamic electrocardiogram. Otherwise, the diagnosis and treatment would have been really delayed. You have a very dangerous and atypical myocardial infarction."
After listening to Director Zhu's words, Xie Fei was also afraid for a while. Fortunately, he met Director Qin. However, Xie Fei looked at the young Qin Lang and couldn't believe it, because Qin Lang was too young.
Not enough, Xie Fei also understood that genius cannot be measured by seniority, and immediately thanked:
"Director Qin, I really want to thank you this time. Your life-saving grace is like rebuilding."
Xie Fei was very grateful, but he was also very puzzled, obviously he had paid great attention to rest and maintenance, and even quit smoking, why did a myocardial infarction suddenly occur.
In the face of Xie Fei's question, Director Zhu could only talk about it in words, but it was all specious speculation.
Director Zhu looked at Qin Lang beside him, and asked with a bit of luck, "Director Qin, what do you think?"
Following Director Zhu's words, Xie Fei also looked at the young Director Qin.
Qin Lang thought about it and asked, "Have you made any changes in your living habits recently, and have you taken any medicine?"
Xie Fei hadn't spoken yet, but Director Zhu, who was on the side, spoke up. He had already consulted in detail before:
"Patient, there have been some changes in living habits recently, but they are all positive changes. It is reasonable to say that it is not the reason for the treatment of the disease..."
After Director Zhu said something, Qin Lang grasped the point:
"Excluding all the impossible, then there is only one possibility. Since these times, your biggest change is to quit smoking and take the smoking cessation drug from Pfizer in the United States. It is very likely that the side effect of this drug exists."
Hearing Qin Langshi's shocking words, Director Zhu was also a little shocked, and Xie Fei's expression changed when he lay on the bed:
"Director Qin, it's impossible. This smoking cessation drug was launched by Pfizer and has been certified by the US FDA. I have asked the pharmacy and read the instructions for this drug. There are no side effects in this regard."
Xie Fei couldn't believe it, but there was a gurgling in his heart.
"Director Qin, I've been taking my medicine on time these days, and I still have a box of smoking cessation pills that I only took two tablets in my pocket."
Xie Fei handed Qin Lang the medicine he had been taking every day from his pocket.
[Ding, the host can consume 1 life simulation point, put the drug into the drug development laboratory for testing, and obtain its detailed pharmacokinetics and side effects. Yes, consume a bit of simulation points to simulate? 】
Of course, Qin Lang chose simulation. In the simulation world, this work was done by the team of Vice President Gao Jun of Zhejiang Provincial Hospital of Traditional Chinese Medicine.
This time, with the help of the drug research and development laboratory, Qin Lang was able to lead the team to complete it, which undoubtedly simplified the whole process, and gave him enough time to fight back against Pfizer.
[Consume 1 life simulation point to simulate tix...simulating...obtain tix pharmacokinetic data...]
【Pharmacokinetics: Absorption peak plasma concentration is reached 3-4 hours after oral administration. The plasma concentration can reach a steady state within 4 days, the oral administration is not fully absorbed, the system bioavailability is not high, and there are some hidden dangers. 】
[Division: tix is distributed in various tissues including brain tissue, and the steady-state apparent division volume is 415 liters (%0)...]
[Biotransformation: The metabolic rate is very low, and 92% of the original drug is excreted in urine...]
[Adverse drug reactions: There is a chance of causing patients to experience restlessness, insomnia, depression, behavior changes, agitation, depression, suicidal behavior, and possible serious mental illness, schizophrenia, bipolar bipolar disorder, major depression, myocardial infarction Infarction, angina pectoris. After taking the drug for seven weeks, the risk of vascular disease is much higher than normal...]
[The simulation is completed, do you get the simulation results? 】
Qin Lang originally only learned about the side effects of this smoking cessation drug through the text information of the simulator, but after the real simulation was completed, it was a little unbelievable.
It can only be said that the side effects of this smoking cessation drug are too great, especially the high probability of increasing the risk of vascular disease.
Where is this smoking cessation drug, it is simply a killing drug.
If it weren't for my own investigation, I believe, in the words of the medical community, I would definitely think that it is because the patients who quit smoking are accustomed to smoking and stop for a while, they will have psychological abnormalities, depression, excitement, etc.
No one will think about the problem of smoking cessation medicine itself. As for cardiovascular disease, it is even more difficult to associate it with smoking cessation medicine.
"I really didn't expect that the US-based Pfizer Pharmaceuticals has no bottom line. In order to suppress the Ming's Pharmaceutical Group, it would act like this."
Through the text description of the simulator, Qin Lang of course understands that the promoters and leaders here are the head of the Huaguo region of Pfizer, and the head of Zhejiang province, who he had offended before.
Its heart can be punished!
With the simulation information of this drug research and development laboratory, Qin Lang only needs to collect enough case data. After all, the results are already available, and only the skeleton needs to be filled.
Qin Lang took the smoking cessation medicine provided by Xie Fei and solemnly issued a doctor's order:
"Xie Fei, don't take this smoking cessation medicine anymore. I will take this smoking cessation medicine to the laboratory for testing. At the same time, your follow-up cooperation is also required. I will take your case data as one of the typical cases. . If it is really the problem of Pfizer's smoking cessation drugs, trust me, I will make them pay enough. I will also provide you with enough compensation!"
Hearing Qin Lang's words, Director Zhu on the side looked sideways, even absurd. If it were another person, he would naturally think it was a little doctor's imagination.
However, it was Qin Lang who said this, and Director Zhu also believed this conclusion. Could it really be a problem with Pfizer's smoking cessation drugs?
When I thought about it, if Qin Lang really came to such a conclusion, it would be a major event in the medical circle that caused an earthquake.
Listening to Qin Lang's instructions, Xie Fei nodded, naturally he did not dare to take this smoking cessation medicine again.
Moreover, if it is really the problem of the smoking cessation pills, as Qin Lang said, he must seek justice!
After instructing Xie Fei with Director Zhu, Qin Lang also left the ward and contacted Wang Rou's team immediately.
According to the current progress, the bupropion smoking cessation drug developed by Qin Lang himself is ready to go.
The team has already invested in the project of new anti-tumor drugs, and Qin Lang has arbitrarily inserted a brand new task, that is, the collection of cases and data on the side effects of Pfizer's new drugs, and the writing of papers.
Wang Rou was a little dissatisfied with Qin Lang's sudden request, but after all, Qin Lang was the boss, so she could only follow Qin Lang's orders without complaint.
Under the coordination of Qin Lang, each hospital also collected some case data and information according to Qin Lang's admission requirements, and immediately provided it to Wang Rou's team.
Looking at the continuous collection of case data, Wang Rou and others also slowly discovered the possible huge side effects of Pfizer's smoking cessation drugs.
Obviously ~www.readwn.com~ Wang Rou and others were also stunned by Qin Lang's big move. Before contacting, Pfizer's Zhejiang Provincial Director Wanfeng's new drug launch was the kind of indomitable, and what about Qin Wang Rou also felt a burst of excitement at the devaluation of Shi's Pharmaceutical Company, Wang Rou's team, and Qin Lang.
If Qin Lang's research direction is correct, then this is a major scandal in Pfizer's long pharmaceutical history, and it will be a big news in the pharmaceutical industry.
Dr. Wang Rou was really shocked by his own boss.
The development of a new smoking cessation drug, and the disclosure of Pfizer's shocking scandal, no matter what happened, it was heart-wrenching!
While Wang Rou devoted himself to the research according to Qin Lang's design, Qin Lang was also preparing to go to Ming's Pharmaceutical Group to carry out his business layout.
After all, if you want to win the Nobel Prize for research projects, you must reach the Forbes elite list under the age of 30, so you can only make a good routine.
But think about it, this is all from his own family, the left pocket goes into the right pocket. Anyway, Qin's Pharmaceutical Company and Ming's Pharmaceutical Group will all be inherited by him and Tang Yue's precious daughter. If you think about it this way, there are no routines or routines. .
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