Genius of the Rules-Style System

Research on the molecular mechanisms of medical pathology is the specialty of the Institute of Biomedical Sciences.

Most of the medicines done by biomedicine have produced many achievements over the past decades. The most recent major achievement is the study of the molecular mechanism of the HIV virulence gene Vif hijacking protein.

Therefore, everyone involved in the project at the Institute of Biomedical Sciences, including people from Zhao Yi's laboratory, as well as researchers such as Dai Tianqing, Han Hui, and Li Ming, are very interested in the research project on the molecular mechanism of 2CV-Binghydrogen molecules against HIV infection. They are confident and believe that completion is only a matter of time. How to conduct research only requires simple discussion. Each of them can independently design the general flow of the research process.

Of course.

Research on the molecular mechanisms involved in medical pathology is still very difficult.

Research at the molecular level requires many problems to be analyzed, and many of the most high-end and professional equipment are used. There is a lot of data that needs to be measured in the process, and the experimental research process is still very complicated.

After the small meeting where the division of labor was clearly defined, the 'Dai Tianqing Research Group' and Zhao Yi Laboratory began to conduct research separately. Because there was a certain degree of competition and it was confidential scientific research, everyone hoped to produce results quickly.

The first step is to inject E. coli and Proteus bacteria into mice and extract the blood after the immune reaction in order to purify a solution containing 2CV-bihydrogen molecules.

This step just takes time to complete.

Because Zhao Yi's laboratory already had the extracted solution, as well as a dozen white mice that had been injected with bacteria for one or two weeks, some of them were given to the 'Dai Tianqing Research Group', so both parties entered the second phase at the same time. stage.

The second stage is divided into two steps. One is to identify the anti-HIV infection effect of 2CV-Binghydrogen molecules, and the other is to find methods and strategies to analyze at which level the anti-HIV infection effect occurs.

For example, at the protein level.

For example, at the level of gene synthesis blocking.

Another example is the process that occurs when genes exert their effects.

etc.

Zhao Yi's laboratory directly skipped the first step. Everyone is very confident in Zhao Yi's conclusion. There is also previous experimental data, so there is no need to continue to verify the anti-AIDS infection effect of 2CV-Binghydrogen molecules.

The ‘Dai Tianqing Research Group’ still carried out verification work, but it was carried out together with the research work. The initial focus was still on the former.

Out of caution when it comes to research, they must first confirm that there is an effect, otherwise all subsequent research will be in vain.

Five days later.

An experiment designed by Ai Lixin and Liu Chengjie found that samples injected with a mixed solution of 2CV-Binghydrogen molecules had an obvious anti-HIV infection effect. Because the concentration of 2CV-Binghydrogen molecules injected was high, the anti-HIV infection effect was very high. Well, the immune system of the mice did not decline rapidly.

At the same time, the HIV concentration test also confirmed a problem.

The concentration of HIV has not dropped significantly, and it is even said to have increased.

Alixin said, "This shows that the 2CV-Binghydrogen molecule can play an anti-infective role, but it does not directly kill HIV, or even directly blocks the synthesis of HIV, but plays a role at other levels."

"It's probably at the infection level..."

This conclusion is very important.

Ai Lixin is indeed an experienced researcher. Zhao Yi used the "Law of Causality" to confirm his conclusion, and decided to say, "Our next focus is to study the 2CV-Bing hydrogen molecule, where in the process of viral infection A level of enlightenment."

Research in Zhao Yi's laboratory quickly entered the third stage.

Yan Xuelin occasionally came over to check on the progress and listened to their internal meetings. He still had other things on his mind.

In the competition between the two research groups, he must be on the side of the 'Dai Tianqing Research Group', mainly because every member of the 'Dai Tianqing Research Group' is a senior researcher. When several researchers work together, the results are better than It’s not as good as a newly established laboratory, especially if there are not many people in this laboratory. Most of them are newcomers. The third-ranked ones are all associate researchers who have just been promoted for a few years. The ‘researcher group’ loses. If so, his director feels that his face has nothing to do with it.

After listening to the small meeting, Yan Xuelin asked for details and hurried to the central laboratory.

That's where the 'Dai Tianqing Research Group' works.

"How's your research going?" Yan Xuelin asked directly, ignoring the pleasantries.

"It's going well!"

Dai Tianqing said with some excitement, "We have confirmed that 2CV-Binghydrogen molecule does have a high anti-AIDS infection effect. The next focus is to study 2CV-Binghydrogen molecule, whether it inhibits the virus or the infection level. played a role.”

Li Ming was cheerful when he came over and was happy with the progress of the research.

Yan Xuelin was not happy at all.

If I remember correctly, during the meeting in Zhao Yi's laboratory, the first sentence jumped directly to 'determine that the 2CV-Binghydrogen molecule plays a role in the infection level', and then directly assigned the next stage of work.

Are you just doing research here?

He took a deep breath and did not say it directly, but pointed in a direction, "I think it is at the infection level, skipping the rigorous research process and directly verifying it."

"Isn't this not good?"

"If the verification is wrong, it takes more time."

"yes."

Dai Tianqing, Li Ming, and Han Hui stood up at the same time to express doubts.

Yan Xuelin shut them all up with one sentence, "I can tell you that this conclusion has been determined over there. You can think about it yourself whether you want to hear it or not."

After he finished speaking, he left.

The three of them looked at each other in disbelief.

Why is the other side so fast?

They have just started preparing for research, and the other side has already come to a conclusion?

"Is it because they have done a lot of research before and have experimental foundations?"

"probably."

"It can only be this way."

Dai Tianqing nodded and said, "Let's just listen to the director and conduct direct experimental verification. The results will be out in two or three days, and we will move to the next step quickly."

…

After the "Dai Tianqing Research Group" set the goal, they moved very quickly. They quickly designed experiments and through a series of tests, they verified that the 2CV-Binghydrogen molecule works at the infection level.

Several researchers felt much more relaxed and quickly held a small meeting to formulate the next step of the experiment.

at the same time.

The new experiments designed by Zhao Yi's laboratory have already made new discoveries.

That was Zhao Yi's discovery.

Through continuous observation of experiments and a series of test data, he soon discovered that HIV did not destroy cells or divide, but reacted with 2CV-Bing hydrogen molecules, causing 'silence', or in other words The phenomenon of 'sleep' means that the ability to infect is greatly reduced.

Zhao Yi expressed his "guess" and discussed it with the people in the laboratory. They analyzed two possibilities. One is 2CV-bihydrogen molecules, which act on the protein structure of the outer layer of HIV; At the genetic level, it weakens the ability of cells to divide and reproduce after genes are injected into them.

Zhao Yi quickly determined that it was acting on the protein level. He checked all the test data, as well as some information related to HIV infection, and came to a conclusion based on the conditions.

Then the laboratory is used to verify the design.

2CV-Bing hydrogen molecules act on the protein level or on the gene level. It is not easy to analyze, but in terms of verification work, you only need to do one thing--

See if HIV can invade cells.

The protein on the outer layer of any virus has two functions. One is to protect the genes inside, and the second is to help the genes invade into cells. After completing the second task, the outer protein structure is to act, and it will was given up directly.

If HIV does not invade cells, it must be acting on the protein structure. After completing the invasion of cells, it must be acting on the genetic level.

Experimental measurement in this area is also very difficult. It requires a long waiting time. It took almost more than a week and several designed experiments to get the exact conclusion. 2CV-Bing hydrogen molecules do indeed act on AIDS. The protein structure of the outer layer of the virus.

Yan Xuelin came again this day.

Yan Xuelin comes around every day to take a look at the progress of the research. He is indeed very concerned because the results also represent the honor of the institute.

At the same time, Yan Xuelin also compared the progress of the two research groups, and hoped that the speed of the 'Dai Tianqing Research Group' would be faster.

When he heard Ai Lixin's report, "We have determined that the effect of inhibiting infection occurs at the outer protein level," Yan Xuelin felt that the progress was going smoothly, but when he thought about the progress of the 'Dai Tianqing Research Group', he had the intention of giving up. .

This gap is too big!

When they arrived at the central laboratory of the institute, they heard Dai Tianqing report, "The last verification greatly accelerated our progress. Thank you. We have designed a new experiment to analyze whether the infection occurred." Which level of the virus, but our analysis believes that it is possible at the protein and gene levels."

"How's it going over there?" Dai Tianqing asked in a low voice, "It should be at this stage too, right?"

"right."

Yan Xuelin replied feebly, "Just finished."

"Just finished? What do you mean?" Dai Tianqing was in a daze.

Yan Xuelin took a deep breath and said, "I mean, they have determined that infection occurs at the protein level."

He sighed, patted Dai Tianqing on the shoulder and said, "Old Dai, don't be offended if I say something bad. I think it might be a mistake to do research in groups these days. You guys always go after them. It’s not a matter of using their conclusions to verify the progress, right?”

"..."

"Why don't you think about it and go there to do research? Would it be faster together?"

"..."

"Let's not divide ourselves into groups. All data, experiments, and results will be shared."

Dai Tianqing still hesitated, "But..."

"But what? You two times in a row are just chasing progress and verifying their conclusions. I didn't say anything, and they don't know."

Yan Xuelin said very seriously, "If you continue like this, what's the difference between stealing results? If you let people know what it's like and let you do it yourself, do you have the confidence to catch up and catch up?"

"..."

"..."

Dai Tianqing and Li Ming who came over stopped talking.

Catching up?

Anyway, there is no hope for the time being.

They found that the opponent was always one step ahead of them, and as soon as they verified the opponent's conclusion, the opponent came to the next conclusion.

They couldn't imagine how the other side studied it.

This is unreasonable!

But it would be shameful for them to say that they don’t need to be grouped into groups and conduct experiments together. They are all leaders of the laboratory and experienced researchers.

What should we do now?

Dai Tianqing and Li Ming looked at each other and didn't know what to do for a moment.

Han Hui said, "Let's take another look. We won't verify the conclusions. We will just do research normally and do whatever we need to do. We will review it next week and make a report together for comparison."

"Let's wait until the review is over."

"All right!"

"I agree!"

"That's it."