Military Technology
Vol 6 Chapter 3357: Most successful organ transplant surgery
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Facing the expectant looks of everyone, Wu Hao was naturally able to guess what these bosses were thinking. So he did not hide it, nodded and admitted: "Yes, we have developed this intelligent bionic artificial liver and have put it into clinical trials. We are currently undergoing phase II clinical trials."
"Phase II clinical trial?" Brother Xiao Ma couldn't help but frowned when he heard this, and looked at Wu Hao in confusion and asked: "I remember that usually the test starts with small animals first, then goes to large animals, and finally Will we conduct clinical trials?"
"Yes, you are right." Wu Hao nodded and explained with a smile: "All clinical trials must be conducted strictly in accordance with this process, and our bionic artificial organs are no exception.
At the beginning of research and development, we first conducted experiments on mice, and then on rabbits, monkeys, pigs and other animals, and all achieved success.
Only after these animal trials were successful did we begin clinical trials. "
Speaking of this, Wu Hao glanced at everyone, and then continued: "The first phase of clinical trials is mainly for the treatment of some patients with end-stage liver disease. We will implant smart bionic artificial livers into these patients to replace their original liver disease." liver function.
After a period of observation, we found that the liver function of these patients has been significantly improved, and the quality of life has also been significantly improved.
This shows that our smart bionic artificial liver is feasible in the human body, and the effect is very good. "
Speaking of this, Wu Hao showed a look of regret and said: "Unfortunately, our smart bionic artificial liver has indeed prolonged the lives of these patients, but it cannot save them.
Because they are in the terminal stage, all parts of their body organs have been affected, and there is still cancer cell metastasis, so many patients eventually passed away.
Of course, there are also problems with our first-generation smart bionic artificial liver. The technology of the first-generation product was not mature enough and there were some problems, so the clinical trial results were not ideal.
But most of them are caused by the condition of the patients participating in the phase I clinical trials, and there is nothing that can be done about it. "
After saying this, Wu Hao sighed again, and then changed his tone and said: "Even so, our intelligent bionic artificial liver also showed excellent therapeutic effects in the first phase of clinical trials. Its stable and reliable performance greatly extended the treatment time." the patient’s survival period.
By submitting it to the expert group and relevant departments for review and approval, we summarized the successful experience of clinical trials, and based on this, optimized and upgraded the first-generation product, improving the performance, safety and reliability of the main product, and then launched the second phase of clinical trials. test.
The so-called Phase II clinical trial is actually to expand the scope of clinical trials and further verify the safety and effectiveness of the intelligent bionic artificial liver.
The second phase clinical trial is currently underway smoothly. We hope to complete this phase as soon as possible, then enter the third phase clinical trial, and finally bring this smart bionic artificial liver to the market to benefit more patients. "
After hearing Wu Hao's explanation, everyone showed a look of surprise, and at the same time, they sincerely admired Haoyu Technology's research and development capabilities in intelligent bionic artificial organs.
"Mr. Wu, since you have started the second phase of clinical trials, when will it be completed?" Mr. Wang, who had been staring at the intelligent bionic artificial liver on the booth, after listening to Wu Hao's introduction, immediately turned to She turned to him and asked.
Hearing Mr. Wang's inquiry and the concerned eyes of everyone, Wu Hao thought for a while and then gave an approximate time: "If everything goes well, we plan to complete the second phase of clinical trials in the next year or so, and then enter the third phase. phase of clinical trials.”
"About a year?" Everyone looked surprised when they heard this.
They know that clinical trials generally take a long time, and they need to be cautious, especially when it comes to human trials.
Therefore, they originally thought that the second phase clinical trial might take three to four years or even longer to complete. Unexpectedly, Wu Hao actually said that it would only take about one year, which was too short.
Faced with everyone's doubts, Wu Hao smiled and explained: "Artificial organs or medical devices are different from clinical trials of traditional drugs. Success is success, failure is failure. Unlike drugs, there are not so many Ambiguity and uncertainty.
At present, our smart bionic artificial liver has a remarkable effect after being implanted in the patient's body. It can completely replace the liver's work, and the patient's prognosis is stable and good.
So what we need to do now is to expand the clinical trial population to cover different patient groups and different diseases, and conduct more adaptive trials.
On the other hand, it is to conduct long-term monitoring and observation of the recovery of patients who have undergone intelligent bionic artificial liver implantation surgery, so as to accumulate more data.
Unlike heart transplants, liver transplants have a very high success rate and a very long survival time.
According to statistics, the 5-year survival rate after liver transplantation for patients with benign liver disease can reach more than 70%, and even the 10-year survival rate can reach more than 50%.
This means that most patients survive for more than 10 years or even longer after surgery. There have been records of liver transplant patients who have survived for fifty years. This can be said to be the longest surviving patient in core organ transplantation.
Therefore, whether our intelligent bionic artificial liver can withstand the test for such a long time is also an important issue that we must monitor and master. "
Speaking of this, Wu Hao took a breath, and then slowly said: "The working life of our smart bionic artificial heart will definitely not be as long as the survival period of living donor liver transplant patients, but we must ensure that it lasts It can run stably and work normally within a certain period of time.
As long as its failure rate is less than one percent within five years and less than 10 percent within ten years, its maximum service life must be twenty years.
And the conditions must be met for another smart bionic artificial liver transplant operation. That is to say, when the performance of this smart bionic artificial liver has problems or its service life is almost over, the patient can promptly replace it with a new smart bionic artificial liver. "
"Twenty years, such a long time, how can we ensure that it does not malfunction? And even if it does not malfunction, the battery life may not be that long." Mr. Zhang questioned.
After hearing this, everyone nodded and looked at Wu Hao, waiting for his reasonable explanation.
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