Please Do Not Disturb My Cultivation
Vol 2 Chapter 457: If you don't make money, what kind of drugs are you developing?
The latest website: Although An Mosi wanted to serve the county governor Lin, he contributed his strength to repay the life-saving grace of the county governor.
But his expression completely betrayed him.
"The concubine can't do it."
Lin Wen understood such a classic expression at a glance.
Isn't your biotechnology very strong?
All kinds of mutants have been made to transform people, and they are just cancers. Why can't they be cured?
Hearing this kind of question, Anmos showed an understanding smile.
This is obviously another accident of a layman commanding a layman.
This is very common in scientific research.
The Qin Group already respects science quite a bit, and this kind of thing cannot be avoided.
In his opinion, the best leaders should let the researchers do it without asking about the results, regardless of the investment, and without setting a deadline.
The next-level leader only asks about the results.
Once again, the leaders of the first level asked for the results, set deadlines, and returned cards.
The worst leaders are those who directly intervene in scientific research.
Although the governor of Changshan County is benevolent and kind, he obviously also has the bad faults of those leaders.
"Chief Lin."
Amers said kindly.
"We are able to compile genes and create monsters that are not found in nature because the great mentor Liman discovered the code of genes and the operation of protein life. We can make certain adjustments to life in this dimension."
"However, cancer is the protoplasm of life's genes, and its biggest feature is the ability to trick the immune system. In this area, our research is not deep enough."
Lin Wendao: "Wouldn't it be over if you don't let it deceive?"
Amers explained patiently: "What Governor Lin said is immunotherapy. Currently, there are cancer vaccine therapy and monoclonal antibody therapy, but what you said is to prevent cancer cells from being deceived and immune, which is very difficult to do. "
"why?"
Anmers said: "Mr. Lin, you should know that the body's immune system is the root cause of curing most diseases, and drugs are just means to control pathogens."
"Immune cells are like guards, patrolling our body all the time, killing invading enemies and keeping us safe."
"These immune guards recognize enemies primarily through proteins."
"If you want to use an analogy, ordinary germs are like thugs, and cancer cells are top secret agents. They will release some special proteins to disguise themselves as normal cells, or reduce the ability of immune cells, or differentiate them with an antigen called antigen. A special protein of cluster 271 that triggers the suicide of immune cells."
"These are the means by which cancer cells protect themselves, **** up nutrients in the host, proliferate like crazy, and by the time we can detect cancer, there are billions of cancer cells."
"At this time, the immune system has basically failed, and cancer cells can only be controlled by external means, such as surgical resection, lasers, microwaves, and targeted drugs."
"Johnson & Johnson's targeted drugs are the best, and they can even cure mid-stage cancers, but they are too expensive."
"In the advanced stage, cancer cells spread all over the body, mix with normal cells, corrode the body, grab nutrients, disrupt order, kill guards, cause immune function decline, foreign enemies invade, medicine stones die, and eventually die of organ failure and various complication."
Lin Wendao: "We release a protein to specifically mark cancer cells, so that they can sneak around and be chased by immune cells, won't it work?"
An Mosi has a headache, and he is most afraid of this kind of leader who only understands half a bucket of water.
"Mr. Lin, the immune response mechanism of the human body is very complex. The protein you are talking about is called pattern recognition receptor protein."
"They can recognize a lot of specific information, such as the structure of bacteria and viruses. These are not the body's own, and once recognized, the receptor protein marks it as an enemy and sends signals downstream, activating an immune response and mobilizing immune cells to Eliminate foreign invaders."
"Currently there is no receptor protein that specifically recognizes cancer cells, and all receptors have low recognition of cancer cells."
Lin Wen asked, "Aren't you able to process protein?"
Amers replied cautiously: "To a certain extent, yes."
"Receptor proteins are equivalent to radar. Cancer cells are characterized by telomere loss. Can you modify this radar to specifically identify telomeres?"
Anmersi fell silent, this opinion was too professional, it was not like a layman could say it.
He thought for a moment and said, "Chief Lin, even if this transformation is feasible, it will be very difficult. It is not something that can be done in a week."
"how long?"
"As short as three or five years, as long as ten years."
Lin Wen asked: "What's your method of transforming protein?"
Amers said: "Many, specifically in this regard, generally use receptor proteins with similar functions, and then fine-tune the structure... This is a very huge project. Just to find a suitable receptor protein, it is necessary to It will take many years and it may fail.”
Lin Wen closed his eyes for a while, and when he opened them again, his eyes were restrained and full of confidence.
"what?"
An Mosi was stunned for a while before he remembered this partial protein.
"Isn't that a differentiation protein associated with cardiac enzymes? Is it reasonable to engineer it?"
Lin Wendao: "Reasonably, its subunit shell helical structure is very suitable. With only a small amount of processing, it can be transformed into the protein receptor we need."
"But...but..." An Mosi choked for a while before asking, "How to mass-produce it?"
Lin Wen closed his eyes for a while and said, "Use No. 281 beafa amino acid enzyme to cover the modified protein, put it in a sterile water-soluble environment with a constant temperature of 21.74 degrees, and store it in a specific ratio of air for 30 hours. By hydrolyzing the enzyme, a large number of active receptors for the protein can be obtained."
An Mosi opened his mouth wide, his eyes bulged out, and the saliva flowed directly into his neck from the corner of his mouth, like a congenital cerebral palsy and acquired cerebral palsy.
"Hello." Lin Wen poked him, but there was no response, "What's wrong with you?"
Amos's whole person was sublimated.
The field of biochemical research is like an endless dark sea.
What you can see is all unknown, the sea is choppy, the dark sea is like a bottomless abyss, and there are countless terrifying monsters lurking, and the monsters will be torn to pieces if you are not careful.
They are exploring in such an environment, without direction.
The appearance of Lin Wen was like a light across the sky, splitting the darkness.
Like a beacon on the coast, pointing their way.
"Leaders who meddle in research are the worst leaders."
Do not.
Amers has now changed his mind.
That is divine leadership.
"Wow ha ha ha ha!"
An Mosi suddenly jumped up, startling Lin Wen.
"I understand."
"I see."
"Chief Lin, you are a genius, Lili in biology, Li Man in biochemistry, being the county magistrate is simply a loss for mankind..."
Lin Wen interrupted him: "Can you do it?"
"can."
"Can you do it for a week?"
"OK!"
"How much does the budget cost?"
"Ten million."
"Do it quickly."
"it is good!"
Anmos jumped up, took two steps, and suddenly turned around.
"Chief Lin, I have another question."
Lin Wen said impatiently, "Fix it by yourself, the primordial spirit is almost gone."
"What is the primordial spirit?"
"A game."
Lin Wen replied casually, unwilling to destroy the scientific atmosphere.
"By the way, what is the cost of mass production of this drug?"
Anmos replied: "One gram is between 100,000 and 300,000, depending on the efficiency of hydrolysis."
"Is it useful for advanced cancer?"
"Yes, we can greatly strengthen the immune capacity and send the patient to the intensive care unit to maintain life. With our current ability, even if the patient is dying, it can be rescued and cured. A large number of mobile receptors will exist for a long time, preventing new diseases. cancer recurrence.”
"Okay." Lin Wen nodded and asked again, "How much is Yu Zhongxian's medicine?"
"A course of treatment is about 1.5 million, which usually requires three courses."
"What about ours?"
"One course of treatment is enough, and the cost is around one million. I suggest that we set a conscientious price of ten million. If the price is set too high, people may be accused of earning the patient's life. "
"Okay, the price is ten thousand."
Lin Wen turned around and went out.
behind.
Ammers became demented again.
After a long while, he was woken up by an assistant.
"Dr. An, Project No. 7 is about to expire!"
Anmos didn't care about the No. 7 project at all, grabbed his assistant and asked the question that he couldn't come up with after thinking about it for a long time.
"If you don't make money, what kind of drugs are you developing?"
——
After coming out of the biochemical base, Lin Wen threw himself into his busy work again, but the calls from the Supreme Military Department came one after another, all urging him to hold a military exposition as soon as possible.
Lin Wen had no choice but to set the time in three days.
Three days later, this week's good fortune will be settled.
Hope to bring him a good luck or two.
In addition, he will also prepare to establish a Jangsan County Academy of Sciences.
Otherwise, where did these technologies come from, it is hard to say clearly.
Moreover, relying entirely on [Ask Yu Tian], this primordial spirit really can't stand it.
With the drug development plan just now, Lin Wen has already exhausted his strength.
Understand all the information, understand the most critical nodes of the problem, and ask very targeted questions.
Under such conditions, he still used up his Primordial Spirit.
Therefore, it is very necessary to establish a scientific research system.
Can't all problems rely on magic, right?
True immortals can't stand this consumption.
However, the establishment of the Academy of Sciences can only be ranked behind.
The first thing he has to do now is to beat the ground, then dig mountains, and then dig subways.
After this is done, a life line of communication in Changshan County that runs through the east and west will be built.
Moreover, at the same time as the construction, it is necessary to take time to blow up Yu Zhongxian.
First of all, he must kill his economic lifeline, squeeze his industry, and strip his power.
Then try to help Li Longxing win, gain enough capital, and take away Yu Zhongxian's fundamental power in one go.
Finally, the most exciting moment.
Yu Zhongxian must not obey the discipline, jumped over the wall in a desperate attempt, and led the backbone of the rebellion to escape.
At that time, it was when Lin Wen appeared.
He will fly over like a **** descending, punch his stinky face with one punch, and step on the bed bug that has been haunting him for a long time.
after that.
The development of Changshan County will no longer be disturbed.
Lin Wen is very much looking forward to such a future.
——
to the Winter Palace.
One of the chairpersons is respectfully reporting the income of the industry to Yu Zhongxian.
"Mr. President, this quarter, the pharmaceutical group's revenue reached 50 billion, more than our revenue in any previous period."
"That's right," Wang Xinwei said with a flattering smile. "You raised the price of essential medicines. This move is too wise. Although we have suffered a lot of criticism, it does not affect the overall situation. No one is not afraid of death."
Dean, the dean, smiled and said, "The dog will come back when he is hungry, and the man will bow his head when he is about to die."
"The fear of death will make them hand over all their money."
"Ha ha."
Wandering in the hall is a sea of joy.
Yu Zhongxian's complexion improved slightly. The recent series of blows made it difficult for the council to move forward.
Fortunately, the Johnson & Johnson R&D base and pharmaceutical companies have saved some of the situation.
"How is the new cancer drug development program?"
Dean Dero replied: "The progress is going well~www.readwn.com~ We will conquer brain cancer soon, and the last bunker of cancer will be dismantled by us."
Wang Xinwei asked, "What is the appropriate price for a new drug?"
Yu Zhongxian said lightly: "Three million, plus a contract. If you can't afford the money, you can sell yourself to the council to pay off the debt."
"Okay!" Everyone cheered in unison: "This method is good!"
"The president is really benevolent and kind, and his merits are boundless!"
Yu Zhongxian raised his hand to stop the touting, and asked again, "What about the advanced cancer project?"
Wang Xinwei replied: "The progress is relatively slow, and we need a large amount of capital to achieve results."
Yu Zhongxian was silent for a moment.
"Then invest another ten billion."
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