Coroner Coroner

At first glance, it was impossible to tell whether his symptoms had become severe due to mild tetrodotoxin poisoning, or whether he was suddenly told something on his mind, which made him so horrified.

"Call the police?"

At this time, Lin Xinyi was still busy doing heart compressions and artificial respiration for the poisoned lady, so he couldn't open his mouth for a while.

On the contrary, Mao Lilan reacted in shock:

"Miss Miyano, what do you mean..."

"This is not ordinary accidental food poisoning, but someone deliberately poisoning?"

"Probably."

Miyano Shiho put his hands in his pockets and said casually:

"Puffer fish dishes are all non-toxic. Even if they are not cleaned up occasionally, such rapid acute tetrodotoxin poisoning rarely occurs due to the small amount of toxins left by accident."

"This Mrs. Yutian must have been poisoned."

"And the poisoner..."

"Probably the only person in this box, Mr. Yutian."

This time, it was no longer a meaningful hint, but an undisguised suspicion.

Tang Tian's face suddenly turned extremely ugly.

He braced his body paralyzed and out of control by tetrodotoxin, and said with righteous indignation:

"Hey, what are you talking about?"

"How could I poison my wife?!"

"Besides... I, myself was also poisoned, obviously there is something wrong with the puffer fish dishes provided by the store!"

"This..." Mao Lilan frowned tightly, a little uncertain.

She thought about it carefully, and finally felt that the arguments given by Miyano Shiho were a bit unreliable:

"This kind of acute poisoning rarely occurs after eating puffer fish dishes. Doesn't it mean that there must be no such cases?"

"If it's true that the store made a mistake in handling the fugu and left a lot of toxins in the dishes, it's not impossible."

"No...you'd be wrong to think so."

"Because Mrs. Yutian's poisoning was so fast and the symptoms were so severe that it is no longer an ordinary acute poisoning."

Miyano Shiho sighed lightly and continued:

"Maybe you know tetrodotoxin is deadly."

"But unlike what you might imagine, even if you eat a lethal dose of tetrodotoxin, people won't get sick and die so quickly."

"Because eating fugu meat is equivalent to oral administration from the stomach."

"And gastrointestinal administration, because it involves the absorption rate of the drug in the gastrointestinal tract, the drug needs to eliminate the interference of food, and has to pass through the cells of the intestinal epithelium, be processed by the liver, and finally enter the blood circulation."

"So, the bioavailability of orally administered drugs, that is, the speed and degree to which the drug is absorbed into the human circulation, tends to be relatively low."

"Speaking of..."

Miyano Shiho paused slightly, recalling:

"When I was 10 years old, I happened to publish a paper on "Pharmacological Analysis and Pharmacokinetics of Tetrodotoxin."

Yutian and Mao Lilan: "???"

Lin Xinyi: "..."

Everyone's eyes were a little weird, but this genius science girl ignored the doubts of ordinary people and continued to say:

"When I was doing experiments on mice, I found that the LD50 of intragastric administration was 12 times that of intraperitoneal injection, which indicated that the bioavailability of TTX (tetrodotoxin) was greatly reduced when administered through the gastrointestinal tract. .”

"By the way, LD50, the median lethal dose, means the minimum amount of toxin required to kill half of a certain animal of a certain weight or age through a specified infection route within a specified period of time."

In order to prevent Mao Lilan from being confused, Miyano Shiho also specially popularized the professional terms he used.

But Mao Lilan was still confused.

Yutian, on the other hand, was covered in cold sweat—even though he couldn't understand it, he seemed very powerful.

"In short, the conclusion is..."

"Oral administration of tetrodotoxin will greatly reduce the speed and degree of toxin diffusion in the human body."

"That is to say, compared with direct intravenous injection, the time of oral poisoning and death will be greatly prolonged."

Miyano Shiho finally said something that people could understand:

"According to research, patients who take tetrodotoxin orally, after a period of incubation, the poisoning time is generally within minutes."

"After the poisoning, the patient will die within 10 minutes at the earliest, and die within 4-6 hours at the latest."

"That is to say... the absorption and distribution of drugs in the human body itself takes time, from oral administration of tetrodotoxin to onset of illness, and then to death. Judging from the current practical case, the shortest time is 20 minutes."

"And Mr. Yuda..."

She turned her head and looked coldly at the pale-faced Yutian:

"You just said that it only takes about 10 minutes for this puffer fish hot pot to be served on the table?"

"In such a short period of time, how did the patient get sick to the point of dying?"

"I..." Yutian was at a loss for words for a moment, and his expression was very exciting:

He didn't expect that the girl in front of him could see such a big flaw in such a simple serving time.

How could this be... Just after taking the poison, you can meet scientists who have researched on this toxin when you go out?

What luck!

If I had known this earlier, I would have done it later.

Tang Tian suddenly fell into apprehension and uneasiness.

At this time, Miyano Shiho continued to say:

"Why did Mrs. Yuda become sick to the point of dying within 10 minutes, maybe less than 10 minutes?"

"Although there is no evidence to say so, if you want me to guess..."

"You probably used something like a syringe to inject tetrodotoxin directly into your wife's vein."

"Because, when taking tetrodotoxin orally, the first thing tetrodotoxin stimulates is the first to contact the gastrointestinal tract."

"In this way, immediately after the poisoning occurs, along with the slight numbness of the fingers and limbs, there should also be symptoms of nausea and vomiting just like you did just now, Mr. Yutian."

"However, Mrs. Yuda had already experienced extremely severe generalized neuromuscular paralysis before she showed symptoms of nausea and vomiting."

"This shows that it is very likely that she did not take the toxin orally, but was injected with the toxin."

"The toxin directly entered the blood circulation system, so it first caused the paralysis of the muscles of the whole body, without causing nausea and vomiting."

By analyzing Mrs. Yuda's condition, Miyano Shiho roughly deduced Mr. Yuda's poisoning method:

"In this way, the onset is faster and the fatality rate is higher. It can almost make people lose their ability to move with muscle paralysis on the spot, and then die in just a few minutes."

"With this fast-acting method of drug delivery, you can safely pretend to be a victim of food poisoning and rush to call an ambulance for your wife."

"Because you know very well—"

"If it is administered orally, there is still a high chance of being rescued."

"However, your wife who injected tetrodotoxin intravenously will be on the verge of death after a short period of time. There is no way for an ambulance to arrive."

"Using this method, you can ensure that your wife will not be rescued after being poisoned, and only then can you ensure that your conspiracy to kill his wife will succeed once!"

Miyano Shiho finished his dark and heavy speculation with a cold tone.

And Yuda gritted his teeth tightly. He couldn't refute Miyano Shiho's "malicious speculation". After holding back for a long time, he could only growl sternly:

"Ah, are you kidding... You said I poisoned my wife by injection, but I was poisoned myself too!"

"That puffer fish hot pot must be poisonous, or you can test it."

Yuda justified himself hysterically.

And Miyano Shiho still had no waves on his face:

"The fugu hot pot is poisonous, and there is no contradiction at all with you injecting your wife with tetrodotoxin."

"After all, you should have injected the poison in the fugu hot pot yourself."

"If you don't poison the food, how can you disguise this conspiracy to kill your wife as an accidental food poisoning?"

"As for you being poisoned yourself... that's because in order to make the illusion of 'food poisoning' more believable, you have grasped the dose and controlled yourself to be slightly poisoned."

Yuda was silent for a while.

He clenched his teeth and refused to admit it:

"Nonsense! It's all just your little girl's speculation."

"After learning a little nonsense, I ran out and talked nonsense..."

"Say I killed my wife, do you have evidence?!"

"evidence?"

As if thinking of something funny, the corner of Miyano Shiho's mouth rose in a playful arc:

"Did you forget, is your wife still alive?"

"I..." Tang Tian choked hard.

And Miyano Shiho continued to mock him:

"Your plot to kill your wife is indeed vicious."

"But it's a pity, you didn't expect that you ran into me and Lin Xinyi as soon as you went out."

"The two of us work together, even the 'dead' who have no signs of life, can work hard to rescue them."

"Now, your wife may not necessarily die."

"Am I speculating wildly, or are you making malicious sophistry? When your wife wakes up, you'll know everything."