Science on the Rise: Starting with Cell Editors

　　"Calm down, didn't it just shoot through the earth? It's nothing special.jpg"

　　"..."

　　Looking at these emojis, Qin Wei's beautiful face was full of smiles.

　　Such a capable, handsome, and interesting guy is an ideal boyfriend.

　　Moreover, as the counselor of Qing University, she was in charge of receiving Lu Li, which also showed that she and Lu Li had a fate.

　　"This is definitely God's will, the old lady must take him down."

　　Qin Wei's face showed a ferocious expression.

　　Just then, the WeChat alert sounded.

　　Seeing Lu Li's reply, Qin Wei almost jumped up from the bed in excitement, stuck her head out and asked her upper bunk, "Jing Jing, you often go out to eat, what's there to eat near our school? I'll bring it tomorrow. people go."

　　When Jingjing heard the words, he immediately became interested, and joked: "Did you take boys there? What's the matter, our Fairy Qin is also moved? There were so many boys who pursued you before, didn't you look down on them?"

　　Qin Wei smiled and said, "That's because they're not good enough. The grades with good looks are not as good as mine, and the grades with good grades are not good, but Lu Li is different."

　　After thinking for a while, he said, "Lu Li? That Lu Li who got a perfect score in the college entrance examination? If I remember correctly, you only met him for the first time today, right? You were arranged by the school to receive him."

　　Qin Wei nodded and said, "It's him. He asked me to take him to see delicious places near the school. He is really super nice."

　　"Mom, it's really him." Jingjing teased: "It's the first time we met. As a senior sister, you are greedy for the junior brother's body."

　　"Bah, bah, what does it mean to be greedy for his body... Well, I'm just greedy for his body, such a high-quality boy, if I don't start quickly, I won't have a chance after school starts."

Chapter 12 Experiment

　　After that, Lu Li had a very comfortable life.

　　The brothers and sisters in the laboratory are very enthusiastic. If he has any questions, the brothers and sisters will take the initiative to help, and he has a good relationship with these brothers and sisters.

　　When he is not in the laboratory, Lu Li usually plays around the school accompanied by Senior Sister Qin Wei. However, he has not confirmed the relationship with Qin Wei yet. As for his relationship, it is better to proceed gradually.

　　At the same time, he also took the time to register a patent related to single-base gene editing technology. This technology is not a black technology that surpasses the times. It is necessary to register a patent first to better protect his interests.

　　Today, eight o'clock in the evening.

　　inside the laboratory.

　　"Junior Lu, see you tomorrow."

　　A senior brother took off his research clothes and said goodbye to Lu Li.

　　"See you tomorrow."

　　Lu Li smiled and continued to observe the cells in the petri dish with the micromanipulator.

　　He is experimenting with single-base gene editing technology.

　　The experimental material was the blood of a cancer patient.

　　He will extract immune cells from blood samples, and then use single-base gene editing technology to inactivate the gene responsible for the PD-1 protein in immune cells.

　　PD-1, also known as the programmed death receptor on the surface of immune cells, once binds to the ligand PD-L1 on cancer cells, it blocks the killing of cancer cells by immune cells.

　　If the experiment is successful, it only needs to inject the gene-edited cells into the patient's body, which can enhance the killing power of the patient's immune cells against cancer cells, benefiting cancer patients.

　　"It's such a hassle to do these experiments in the lab."

　　Lu Li sighed softly.

　　Through the cell editor, he can perfectly control the cells in his body and perform atomic-level operations on any substance in the cells. As for modifying genes, it is not too simple.

　　However, it is very troublesome to use these instruments in the laboratory to perform experiments. The existing instruments cannot perform precise manipulation of genes, and special methods must be used. The single-base gene editing technology he constructed is one of them.

　　"Hey, it can't be said that the current equipment is too backward, the main reason is that my plug-in is too strong."

　　Lu Li smiled again and continued the experiment.

　　After a long night of research, it was soon bright.

　　Professor Xu was wearing a research uniform and walked in. Seeing Lu Li, he said with some concern: "You didn't rest last night, you have been doing experiments?"

　　"The experiment reached a critical stage where I needed to keep an eye on it, and luckily it was a success."

　　Lu Li showed a bright smile, picked up an experimental data report and handed it to Professor Xu, "I used single-base gene editing technology to successfully inactivate the gene responsible for the PD-1 protein in immune cells, and the off-target rate is very low. , only 1.3%.”

　　The so-called off-target refers to editing other genes.

　　For example, if you want to edit the A gene, you end up editing the B gene.

　　This is a serious security risk.

　　The current mainstream CRISPR-Cas9 gene editing technology is highly off-target, which is an important reason why CRISPR-Cas9 gene editing technology has not yet been commercialized.

　　"I'll take a look!"

　　Professor Xu excitedly took the document handed over by Lu Li and read it. The more he looked, the happier he became, and a bright smile gradually bloomed on his face.

　　"Sure enough, as I judged, the single-base gene editing technology you invented is at least ten times more advanced than the CRISPR-Cas9 gene editing technology. With this technology, the field of gene editing technology will enter a new era. However, these The data is not enough, you do a few more sets of experiments, collect some data, and then you can write a paper, after writing, I will look at it for you, and then submit it to "Cell"."

　　Professor Xu said excitedly.

　　Lu Li nodded, and did not bother to rest. He ate something in a hurry, and continued the experiment. He was busy until the afternoon, and completed four more sets of experiments and recorded the experimental data.

　　"Perfect!"

　　Professor Xu has been observing and guiding by the side. Seeing these data, he slapped his thigh and groaned with excitement. Once again, he felt that accepting Lu Li as a student might be the most proud thing in his life.This student is simply genius!

　　"I rub it, you are awesome!"

　　"Lu Xuedi, from now on, you are my idol!"

　　"Judging from these experimental data, single-base gene editing technology is more advanced than CRISPR-Cas9 gene editing technology in all aspects, and can completely replace CRISPR-Cas9 gene editing technology! My God! The biological world is about to have a big earthquake! "

　　"Junior Lu will be the capital I brag about in the future."

　　The others were also watching, and at this moment they couldn't help cheering. Looking at Lu Li, their eyes were full of envy and respect, as if they saw a great scientist rising.

　　As for jealousy, there is no such thing as jealousy. When the gap is small, jealousy will arise. When the gap is large to a certain extent, you can only look up and worship!

Chapter 13 Really fragrant!

　　Lu Li was already very tired. After discussing the thesis with Professor Xu, he went back to the dormitory to rest and slept until the next morning. After waking up, he opened WeChat and saw the message sent by Senior Sister Qin Wei. The message is just a few numbers: "9, 12, 15, 22, 5, 21."

　　However, Lu Li smiled knowingly.

　　Senior Sister is so interesting, even if she confesses, she has never taken the usual path.

　　I used to use mathematical formulas, and now I use passwords.

　　He saw it right away.

　　9、12、15、22、5、21……按照英文字母的顺序进行对照的话，分别代表的是I、L、O、V、E、U。

　　All together: ILOVEYOU.

　　"let's have dinner tonight."

　　With a smile on the corner of Lu Li's mouth, he edited a message and sent it to his senior. Then he began to organize the paper. After writing, he went directly to Professor Xu's office and revised the paper under the guidance of Professor Xu before submitting the manuscript to Cell magazine.

　　Then, he went straight to the library.

　　Qing University's library is very large, and there are professional books in various disciplines organized. For Lu Li, these books are precious treasures.

　　The 103 professional books purchased online made him a top biologist in the world, and he developed the single-base gene editing technology!

　　If he thoroughly learns all the related books of life science major in the Tsingtao University library, he will stand at the top of the global biology community!

　　Not only that.

　　During this time, Lu Li still had a lot of fantastic ideas.

　　For example: making biological computers.

　　In theory, this is perfectly feasible.

　　Just use bioengineering technology to produce protein molecules and use them as biochips to replace semiconductor silicon wafers, using organic compounds to store data.

　　The computing speed of this computer can reach 10 times that of the latest generation of supercomputers, and it will form a whole new industrial chain.

　　At that time, Microsoft, Intel and other powerful technology companies will be waiting to go bankrupt.

　　For example: to make a chlorophyll protein that can be parasitic in human skin cells, so that humans can perform photosynthesis and produce oxygen like plants.

　　For example: transforming cells into atomic furnaces can directly produce nuclear reactions and convert matter into energy.

　　For example: to create a star behemoth that can fly directly into space and survive in space.

　　Lu Li believes that these brain holes are completely possible. After all, he has the awesome plug-in of the cell editor.

　　However, the cell editor also has to follow the laws of science, so in order to realize these brain holes, he must have enough knowledge.

　　Therefore, Lu Li has already made a plan. After he has finished reading the books for life sciences, he will continue to read books in various disciplines such as physics, chemistry, and mathematics.

　　……

　　Across the ocean.

　　Elsevier Press.

　　The name of this magazine is very common, but its "Cell" magazine is one of the three top scientific journals with the same name as "Science" and "Nature".

　　Scientists from all over the world are eager to publish in one of these journals, as it represents the highest level of scientific research in the world.

　　As long as you can publish papers in these three journals, it means that you have become a figure in the scientific community.

　　What is Daniel level?

　　In China, it is equivalent to the level of an academician of the Chinese Academy of Sciences.

　　Many domestic scientists have been elected academicians by virtue of their papers published in these three journals.

　　at this time.

　　"Cell" magazine editorial department, editor's office.

　　Raymond is reading submitted papers from around the world.

　　"Combining visual neurobiomedicine with innovative nanotechnology to achieve naked-eye infrared light perception and infrared image vision capabilities in animals... Well, this paper is ok."