Start From Emergency Doctor

Chapter 165

Generally struggling for nothing.

Zhou Yuan pressed its head, and then carefully took apart the gauze.

The paws under the gauze were scratching restlessly, and the sutures were visible to the naked eye, but they already had the preliminary characteristics of survival.

Zhou Yuan checked again.

The distal veins are unobstructed, capillary circulation is normal, and nerve reflexes are somewhat sluggish, but there is no problem at all.

Zhou Yuan moved away to look at Da Bai and Xiao Bai.

Although the curative effect is inconsistent, the final result is the same. The paw after transplantation…a perfect survival!

In other words, this operation is completely feasible!

Zhou Yuan stood up a little excited.

Now… only one patient is left to prove this theory!

If successful, then this operation is likely to be included in the history of the medical field of amputated limb replantation…

For accuracy, Zhou Yuan changed the positions of the other two front and rear paws of the three mice overnight, and then gave the mice seven or eight potato chips.

Mouse: I’m so difficult.

After three times a night, Zhou Yuan was also a little tired. Looking at the three white mice lying on the table, Zhou Yuan smiled with satisfaction.

The three operations went smoothly, and if there were no accidents, the mice’s retransplanted limbs should also be able to survive.

Of course, you still have to wait until the evening to see the preliminary results.

Zhou Yuan rinsed quickly and glanced at the date.

Yes, it was Monday, and I did go to work today.

After walking for almost ten minutes, Zhou Yuan arrived at the emergency department.

Liu Kai and Haiyang also happened to be at work. Seeing Zhou Yuan, they greeted them enthusiastically.

“Junior Brother Zhou Yuan? Yesterday, I checked the duty schedule. Wasn’t Director Liu on duty in the morning? Why did you sit in the clinic when I went to change shifts?” Liu Kai was a little confused.

I just said that I felt something was wrong, and I thought I had memorized the wrong schedule.

Zhou Yuan’s mouth twitched: “I’ll help Director Liu take a class.”

Liu Kai frowned. “Director Liu has just been sent to the operating room. It seems to be getting bone marrow. I don’t know who it is for.”

“Don’t say it, the master is here!” Haiyang glanced at the back in a panic, and was about to run back to his clinic.

Zhou Yuan also looked over. He Jianyi was rushing out of the office and hurried to the operating room.

“Ocean, what are you running? I’m not catching you to be lazy.” He Jian glanced helplessly.

Zhou Yuan instinctively became vigilant, and followed He Jianyi to the operating room.(Read more @ wuxiax.com)

“Teacher, what happened?” Zhou Yuan asked.

He Jian had a serious face, “Can’t get the bone marrow!”

“Director Liu?”

“Yes, now her daughter Haoyue is already lying in the transplant warehouse waiting for the bone marrow to be transplanted. If the bone marrow cannot be extracted from Liu Huimin’s body, Haoyue’s life is in danger!”

Zhou Yuan’s face also became serious.

Before hematopoietic stem cell transplantation, patients usually undergo long-term chemotherapy, which will cause irreversible damage to the body. If Liu Huimin’s hematopoietic stem cells are not obtained, then Haoyue has only one choice.

The previously destroyed hematopoietic stem cells were returned to the body and barely survived.

Because, apart from Liu Huimin matching her bone marrow, it is too difficult to find a second suitable bone marrow…

For bone marrow transplantation, the donor and patient must have HLA antigen matching. The probability of a complete HLA matching among siblings is one in four, while the probability of an HLA matching among unrelated donors in the Celestial dynasty is only tens of thousands to a few hundred thousand.

Moreover, there is one more thing worth mentioning.

The HLA gene is located on human chromosome 6. Like other chromosomes, chromosome 6 is also a pair, one from the father and one from the mother.

Therefore, half of our HLA genes are the same as our parents. In other words, our parents and we are 50% identical in HLA genes.

This is a bone marrow with incomplete matching. Under normal circumstances, it will not be used because it will increase the incidence of postoperative complications, rejection reactions, and so on.

Since Haoyue has come to the step of seeking Liu Huimin’s help, it shows that her condition can no longer wait. Choosing to transplant Liu Huimin’s bone marrow is already a last resort.

It can also be understood that if the bone marrow transplant fails this time, Haoyue’s life will be announced.

“What are you doing with you, can you do a bone marrow transplant?” He Jian asked, tilting his head.

Zhou Yuan said: “I have learned a little.”

He Jianyi: “…”

“Hurry up!”

Zhou Yuan asked: “Which method does Director Liu use to obtain hematopoietic stem cells?”

“Peripheral blood stem cell transplantation!”

“Not a classic bone marrow transplant?” Zhou Yuan frowned.

In fact, there are three methods for the treatment of leukemia by extracting hematopoietic stem cells. The first is simple and crude bone marrow transplantation, the second is peripheral blood stem cell transplantation currently done by Liu Huimin, and the third is cord blood stem cell transplantation… …..

Peripheral blood stem cell transplantation uses a mobilizer to release hematopoietic stem cells from bone marrow to peripheral blood, and then collect hematopoietic stem cells from circulating blood through a blood cell separator.

Compared with bone marrow transplantation, this kind of transplantation has the advantages of convenient collection, no need for anesthesia for the donor, and quicker recovery of hematopoiesis after transplantation.

Moreover, the incidence and severity of graft-versus-host reaction after surgery will be reduced.

However, peripheral blood stem cell transplantation is a technology that has only recently developed and is not fully mature, so there may be many defects and undiscovered dangers.

What Liu Huimin encountered today was one of them.

The two quickly prepared for the operation, washed and disinfected their hands in seven steps, and then entered the operating room and put on surgical gowns.

Originally, peripheral blood stem cell transplantation did not need to go to the operating room. Just like a blood draw, it can be done on the hospital bed. However, because Liu Huimin’s hematopoietic stem cells were not drawn, they were sent to the operating room.

“Hasn’t it been extracted yet?”

He Jianyi took Zhou Yuan to the operating table.

“Not yet! Only a small amount of hematopoietic stem cells! We have almost drawn a round of peripheral blood!” The hematology doctor said anxiously.

He held a special blood cell separator in his hand, one side was drawing blood, and the other side was a reflux device.

Because only hematopoietic stem cells are needed, this instrument will leave the absorbed hematopoietic stem cells, and the blood cells will be returned to the donor through the reflux device to minimize the harm to the donor.

“Is there not enough mobilizer? Why didn’t hematopoietic stem cells enter the peripheral blood?” He Jianyi asked seriously.

“Enough is enough. We were giving mobilizers every day for a week before the bone marrow transplantation, but we didn’t expect the stem cells in the bone marrow to be discharged!”

Liu Huimin, who was lying on the hospital bed, looked pale at the moment.

Although a large amount of blood drawn and reflux did not reduce her total blood volume, the damage to the body still exists.

“Stop smoking, let’s have a bone marrow transplant…I want to save my daughter.” Liu Huimin’s voice rang.

“Bone marrow transplantation…can’t be done…” the oncology doctor said desperately.

“Why?” Liu Huimin’s face became paler.

She is a doctor in the emergency department, and she only has a general understanding of this knowledge. However, she also knows that peripheral blood stem cell transplantation is not acceptable and can be replaced by bone marrow transplantation!

Why is it not working now…….