Start From Emergency Doctor

Chapter 415

These sequelae of cyclosporine are all based on individual patients. If there is a sequelae, there must have been such patients.

Although cyclosporin increased the survival rate, a small number of patients were blind and affected for life, and some even died.

This is not unacceptable for some patients undergoing heart-lung transplantation, but it is a fatal blow to those who have not yet reached the advanced stage and whose organ transplantation is only to improve the quality of life.

Of course, for Chen Jianguo, lung transplantation had to be done.

The choice of immunosuppressive agents is also related to his life after the operation. Controlling the degree of immunosuppression, and finding a balance between reducing the chance of rejection and preventing infection by foreign pathogens can completely save Chen Jianguo.

Zhou Yuan didn’t think for too long. This operation, which could have been completed in about eight and a half hours, was delayed by Zhou Yuan to ten hours. One of the reasons was that Zhou Yuan was evaluating Chen Jianguo’s physical condition.

The choice of immunosuppressant must be changed according to the patient’s own situation, there is no best, only the most suitable.

Zhou Yuan thought about it for a while, and then methodically said: “First, give an intravenous infusion of methylprednisolone, with a specification of 0.5-1mg/(kg·d) for two days, then stop the infusion and start oral prednisone with a dose of 0.5mg. /(Kg·d), gradually reduce the amount.”

Methylprednisolone is an anti-inflammatory drug, mainly used for the rescue of critical diseases, but also for endocrine disorders and so on. Of course, the most widely used is clinical organ transplantation.

And reducing the oral dose of prednisone is to prevent the complications of long-term use.

Zhou Yuan continued: “After the oral administration, change azathioprine 1 to 2 mg/(kg·d) to maintain a white blood cell count greater than 3.5×109/L. At the same time, start oral cyclosporine 5mg/(kg·d) on the second day after 12h). Maintain the plasma concentration at 250-300ng/ml.”

He did not use cyclosporine, which is the most widely used clinically, and Chen Jianguo’s body can no longer bear serious complications.

Zhou Yuan chose some immunosuppressants with relatively mild potency, and also matched some other drugs to prevent serious low-immune complications.

For example, oral cyclosporine, taken after immunosuppressive agents can reduce nephrotoxicity and greatly reduce the damage of immunosuppressive agents to the body.

Jiang Li was surprised. Zhou Yuan’s medication method was very similar to Professor Chen Jingyu’s, but he could feel that Zhou Yuan seemed to be better at handling details…

The head nurse who came here was even more surprised. She has been dealing with postoperative care for 40 years and is familiar with all kinds of drugs. Zhou Yuan’s drug delivery method is definitely the most suitable for Chen Jianguo!

She nodded and wrote it down, and immediately pushed Chen Jianguo to prepare for nursing.

Of course, the head nurse is only experienced in the nature of the medicine, but if she is really asked to dispense the medicine, it is still very difficult.

The division of labor between doctors and nurses is different. The doctor’s orders are prescribed by the doctors, and the nurses just follow the doctor’s orders. In addition to performing their tasks in accordance with the doctor’s orders, they also check the rationality of the doctor’s orders.

Therefore, doctors are good at coordinating ability, and nurses mainly have amazing appraisal and review ability. She can see that Zhou Yuan’s medication method is very appropriate, but if she is required to prescribe a medication, I am afraid that it is not as good as the senior doctor. division.(Read more @ wuxiax.com)

“Dr. Zhou, Director Yuan and Director Zhan are all here, they want to see you.” Jiang Li glanced at the phone and said.

Zhou Yuan originally planned to go back and have a rest, but he was taken aback when he heard Director Yuan: “Director Yuan Shaoyuan?”

“Yes, you met him before, and he went to Yanjing Chinese Medicine to find you.”

Zhou Yuan twisted his stiff neck, nodded and followed Jiang Li to the conference room.

The conference room had already been emptied, and only Yuan Shao and Zhan Ting remained.

There was a knock on the door, Yuan Shao and Zhan Ting stood up at the same time, looked at each other, and both saw the excitement in each other’s eyes.

“Please come in.” Zhan Ting said as the host.

Zhou Yuan and Jiang Li appeared at the door.

“Long time no see.” Yuan Shao rarely greeted Zhou Yuan.

Zhou Yuan smiled in return.

Jiang Li winced, and said, “I will leave first if there is nothing to do with me.”

As he said, he quietly brought the door of the meeting room, and there were only three people left in the meeting room, Zhou Yuan.

“Sit down.” Zhan Ting sat down first and said.

With the three of them seated, Zhou Yuan was still a little confused.

How come I came across two national-level figures…one from the Education Bureau and the other from the Health and Family Planning Commission.

The Education Bureau has nothing to do with Zhou Yuan. It’s just that because of toe transplantation and thumb reconstruction, he occasionally contacts with the textbook editorial board.. ……

However, the Health and Family Planning Commission is directly related to Zhou Yuan. Hospitals across the country are under the management of the VIA Department, and the doctors’ jobs are in the hands of the Health Family Planning Commission.

“There was a meeting recently. Are you interested in participating in the National Lung Transplant Program.” Zhan Ting said.

Yuan Shao next to him was already prepared, but when he heard Zhan Ting’s invitation to Zhou Yuan to participate in the meeting, his heart was shocked!

Any plan, as long as it has something to do with the country, then it may be a great plan concerning the livelihood of millions of people!

From a medical perspective, it may not be so amazing, but what about the “Atomic Bomb Research Project” and the “Nuclear Submarine Research Project”?

The National Lung Transplant Plan is at the same level as these plans!

As the chairman of the Health and Family Planning Commission, Zhan Ting specially invited someone, basically he hoped that the other person would join the plan.

In medical research, who is not an old expert in his 50s or 60s? The old scholar in his 70s or 80s dragged his half-old body out. Young scholars and doctors have no experience at all and are not competent!

It is definitely the first time for someone as old as Zhou Yuan to be selected by Zhan Ting as a seedling of the National Lung Transplant Program!

Zhou Yuan was also a little flattered, he naturally understood the meaning of Zhan Ting’s words.

However, Zhou Yuan is not interested in these things. He has only one idea now, which is to perfect the thumb by transplanting the toes on his hand, pioneering the modified reconstruction of the finger after transplantation, and doing in-depth research in the psychiatric department.

Zhan Ting seemed to see Zhou Yuan’s thoughts and immediately said: “We don’t want you to be buried on the operating table!”

Yuan Shao was embarrassed and said, “I asked you to join the National Z Medical Association before. As a result, you never participated in the meeting. Those people who want to see you are almost crazy. They look at your sign every day…”

Zhou Yuan:? ? ?

Yuan Shao: “Oh, it’s not a sign. A place will be reserved for you during the meeting. The sign on it says your name.”

Zhou Yuan:…

Zhan Ting meditated. After a long time, he raised his head, stared at Zhou Yuan, and said in a solemn tone: “The national lung transplantation plan has been included in the country’s future plans as a major scientific and technological project. Many Z scientists are working hard. Yu captured this field of natural science, which included academicians of the Chinese Academy of Sciences, lung transplant experts, physiologists, thoracic surgery experts, etc.”.