Start From Emergency Doctor

Chapter 424

Almost no one noticed this detail, because it is so inconspicuous.

However, Zhou Yuan’s nerves tightened immediately, “A cluster discharge occurred!”

Normal mice have single firings of neurons, but cluster firings have just been discovered in depression mice!

For example, the original electric discharge of a mouse was a shotgun, but the cluster discharge turned into a machine gun. The bullets were fired densely and efficiently, and the transmission of information became extremely efficient and would not be scattered.

“Cluster discharge?” Someone was stunned.

They never noticed that the mice had cluster discharges!

“What does the cluster discharge have to do with depression in mice?” someone asked.

Zhou Yuan looked excited: “Depressed mice have negative emotions. The cluster discharge will amplify the signals transmitted by neurons, which is equivalent to strengthening the inhibitory effect of the lateral habenular nucleus, making the mice feel unhappy and causing depression. !”

This is like using a shotgun and a machine gun to attack a person ten meters away. The former may not even be able to hurt the opponent because the bullets are too scattered, but the machine gun can accurately hit the enemy~!

The cluster discharges exactly cause depression!

Of course, this is only Zhou Yuan’s conjecture, and the specific results need to be verified by experiments.

Zhou Yuan held back his excitement and began the final verification.

The method is very simple. Before this experiment, the researchers conducted forced swimming experiments on other mice. Depressed mice would give up struggling and drown after falling into the pool. However, normal mice kept struggling to survive. Survived in a swimming stance.

Zhou Yuan simulated the cluster-like discharge, which stimulated the neurons of normal mice to emit electrical signals similar to the lateral habenular nucleus.

Almost at the next moment, a magical scene appeared. The mice that were not depressed instantly showed a variety of typical depressive behaviors, and completely gave up the struggle and sank into the water!

“What is the role of ketamine!” Zhou Yuan became excited.

He immediately supplemented the depressed mice with ketamine, and performed the current test again, and found that the cluster discharge of the lateral habenular nucleus disappeared!

Why does ketamine make the cluster discharge of the outer habenula disappear! What’s the matter with cluster discharge?

These have not been determined by the scientific community. Even the term cluster discharge is just a definition. As for the specific use and under what circumstances it may happen, it is unknown.

At this time, these unknowns have also become a problem that hinders Zhou Yuan from uncovering the final result of the experiment!

Without any hesitation, Zhou Yuan plunged into the laboratory and started research.

The researchers were stunned for a moment, staring in horror at Zhou Yuan, who had entered the research state.(Read more @ wuxiax.com)

“Successful?!”

“No… he is still so young! I have never seen this experimental idea before, it is amazing!”

“How can there be such a young scientist. Yes, I think he deserves the title of scientist now, at least we don’t have his clear thinking…”

“Scientific research experiments have always corrected mistakes step by step, and experiments have been gradually improved amidst mistakes. If I remember well, this is Zhou Yuan’s first scientific research experiment. The experiment he designed was also a success!”

“Like an experiment in a textbook, there is no need to doubt whether it is correct or not. If it is not done, it is not that the experiment will not work, but that our operation is not standardized…”

Someone in the laboratory intends to talk to Zhou Yuan, but finds that Zhou Yuan has finished immersing himself in his own world and is constantly conducting repeated experiments.

It wasn’t until the evening that Zhou Yuan came back to his senses, his expression extremely excited.

“The cluster discharge of the lateral habenular nucleus relies on NMDAR, the most important excitatory transmitter in the brain, glutamate receptor, and ketamine happens to be a blocker of NMDAR. After taking it, ketamine can organize NMDAR to work, and it will completely block it. The neurons in the lateral habenular nucleus fire in clusters!”

“Without cluster firing, neurons resumed a single firing. The negative emotions generated by the lateral habenula are like shotguns. They cannot be shot in one spot, so they will only cause temporary bad moods and will not cause depression! ”

A cloud of dark clouds in Zhou Yuan’s heart suddenly dispersed.

The researchers looked at each other: “You mean…Ketamine blocked the cluster discharge and directly cut off the cause of depression!!”

Before they knew it, they had begun to use honorifics when they called Zhou Yuan.

Zhou Yuan smiled and nodded in a very relaxed tone: “Yes, although ketamine is a drug component, it does not relieve depression through the hallucinogenic effects that people have guessed, but instead relies on blocking cluster discharges to block the occurrence of depression. mechanism!”

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The leader of the scientific research team ran out of the laboratory excitedly and dialed Zhan Ting’s phone.

“Chairman Zhan, something big has happened… You come to Yanjing! something big has happened!”

…

After receiving the call, Zhan Ting was completely confused.

The person who called was a competent scholar in the team, who was very good at doing experiments. In the lung transplant experiment, he also led another team to overcome difficulties, but because the lung transplant experiment has reached a bottleneck in recent years, he temporarily put it aside After coming down, he was handed over to Zhou Yuan.

But, before a month, he called and said something went wrong…

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Does the experiment violate ethics? Or did it cause an accident and trigger a social controversy?

Before Zhan Ting had time to inquire, the other party directly hung up the phone and happily followed Zhou Yuan to continue the experiment to re-verify and finish the work.

For those concentrating on scientific research, what is the chairman of the Health and Family Planning Commission? He will soon follow Zhou Yuan to re-verify and finalize the experiment. A call to report is already the limit. He is too lazy to be on Zhan Ting. Waste valuable research time.

Sure enough, when Zhan Ting wanted to call, the other party had already shut down…

“No way, something big happened…” Zhan Ting’s face was a little ugly.

Would it be too hasty to ask Zhou Yuan to lead a team in scientific research?

He is a talent in the operating room, but he has never shown talent in scientific research!

Moreover, Zhan Ting has also seen Zhou Yuan’s results in school. Although the experimental class results of the medical school are top-notch, they are not so good that they can independently complete experiments and conduct scientific research…

But at that time, Zhan Ting had already agreed to go out, so he could only bite the bullet and give it to Zhou Yuan.

Sure enough, something happened now!

Zhan Ting checked the Internet and saw that the condemnation of Zhou Yuan on the Internet was almost all about the topic of “emergency doctors intervening in the work of psychiatrists”, which was full of doubts and abuse.

Although Zhan Ting was also a little worried about Zhou Yuan, his face became cold when he saw these remarks, and he said coldly: “A master who has created a new field of medicine, is you worthy of insult?!”