Chapter 438

The more Xiao Xuemo thought about it, the more he realized something was wrong, and later he became completely autistic.

When Zhou Yuan announced that the operation was over, Xiao Xuemo was completely dazed, and followed Zhou Yuan out of the operating room in a vague way.

Yang Lin’s family is already waiting outside.

During the operation, Yang Lin’s wife and daughter were unwilling to leave for a while, for fear that the doctors would suddenly come out and give a critical illness notice, or say, “We tried our best.”

To be honest, the longer the operation, the more at ease the two of them. Of course, if it takes too long, they will be afraid again.

Fortunately, the door to the operating room finally opened, Zhou Yuan and others walked out, and Yang Lin’s wife immediately took her daughter and walked quickly to Zhou Yuan.

One big and one small, two women just stood in front of Zhou Yuan, chattering at the corners of their mouths, but they couldn’t say a word.

Zhou Yuan took off his mask and smiled lightly, revealing his pale handsome face.

It was vaguely visible that there were fine beads of sweat on the face, and the sultry environment of the operating room, coupled with the heavy surgical gown, made the doctors present uncomfortable.

“The operation was very successful.” Zhou Yuan’s voice seemed to be the rain after the heavy rain, and the sluggish expressions of Yang Lin’s wife and daughter suddenly came to life, excitedly looking in the direction of the operating room…

After a heavy rain, the temperature in Yanjing finally dropped.

November is coming to an end. The heavy rain seemed to announce the arrival of early winter, and the temperature in Yanjing dropped overnight.



It took a couple of days to go from short sleeves to down jackets…

It was also at this time that Zhou Yuan’s paper was released.

Zhan Ting himself is the chairman of the National Family Planning Commission. Few people can compare the power in terms of resources. Besides, Yuan Shao is pushing behind, and Yang Shuxin more or less participated in the review after Zhou Yuan completed the paper. Soon it was delivered to “Nature” magazine.

“Ketamine blocks the lateral habenula and quickly relieves depression.”

The title of Zhou Yuan’s paper is very concise, but this title alone is shocking enough!

Depression is a mental illness. There are not many international publications on mental illness, and there are very few internationally authoritative publications. It is impossible for Zhou Yuan to submit his paper to The Lancet, which focuses on surgery. The most suitable one is Natural “magazine.

“Using optogenetic technology, the experimental group induced cluster discharges in the lateral habenula of mice in real time. A magical scene appeared. The mice that were not depressed instantly showed a variety of typical depressive behaviors. This is in the field of depression. For the first time, it is the first time that only a certain brain area’s electric discharge mode is changed, thereby inducing depressive behavior.”

“As a result, the mystery of the rapid onset of ketamine has also been revealed in the experiment. The team used brain slice electrophysiology and mathematical modeling to prove that ion channels located in the lateral habenular nucleus play an important role in the discharge of nerve clusters. The effect is that the use of ketamine to block ion channels can achieve a rapid antidepressant effect.”(Read more @ wuxiax.com)

“This series of studies clarified the new brain mechanism of ketamine’s rapid antidepressant effect-that is, ketamine can block the cluster discharge of the lateral habenular nucleus, and then release excessive inhibition of the downstream monoamine reward brain area, and finally produce rapid antidepressant. Efficacy.”

“…”

Zhou Yuan’s paper was almost sent to Zhan Ting, who was shocked to speak!

Although he is not a psychiatrist, he still has basic vision when he sits in this position. He clearly knows how important Zhou Yuan’s research is.

After contacting the editor-in-chief of Country Z of the journal Nature, the latter studied for five hours and finally gave an evaluation: “About the involvement of the NMDA receptors in the lateral habenular nucleus in mediating cluster discharge and the antidepressant effect of ketamine. The discovery of the role is very important, innovative! And has a wide range of significance!”

Zhan Ting knows the editor-in-chief of Country Z. His vision has always been very vicious, but his evaluation is very high.

This is a major breakthrough for depression, and hundreds of millions of depression patients will benefit the world!

The Fourth Military Medical University, Union Hospital, and several hospitals specializing in mental illness research were all invited to participate in the review, and the conclusions they gave were similar.

After the basic idea is summarized, there is only one sentence left-

“Zhou Yuan is awesome!”

Wu Sheng, the editor-in-chief of Country Z of “Nature” magazine, said, “Although the road to drug research and development is still very long, with this paper as the theoretical basis, we have seen the dawn and have taken the first step. !”

The other judges were also extremely excited.

Those who are eligible to participate in the paper review are actually domestic psychiatrists, and even some experts invited from abroad.

Which one of them is not spending their entire life on mental illness, and among them, depression with a low incidence and a large number of people is the most serious, and they are thinking about how to save those depression patients almost every day.

At this time, Zhou Yuan’s paper came out.

Originally, everyone was still walking in the dark, but now Zhou Yuan gave a direction, that is, the cluster discharge from the outer habenula broke through, like a lighthouse suddenly lit up in the dark.

Wu Sheng knew that when Zhou Yuan’s paper was published, the conclusion that “ketamine blocks the lateral reins to quickly relieve depression” will be like a depth bomb, boiling the entire spiritual realm! !

Sure enough, three days later, Zhou Yuan’s paper occupies a full eleven pages!

What is this concept?

“Nature” is the world’s earliest international scientific and technological journal. Not only medicine, but also cutting-edge science and technology are eligible to be published in “Nature”.

The content of each issue of “Nature” is not much, mostly one or two pages of scientific discoveries, scientific breakthroughs, and even a half page of research in many cases.

About seven or eight pages or more, there are only one or two in each issue. The gold content of “Nature” magazine is very high, it can be said that it is a thousand words, and naturally it will not waste the page.

And being able to occupy ten pages, one can imagine how important this research is!

Moreover, “Nature” magazine invited international peer experts to comment on the significance of this research in the “News and Review” column, which is equivalent to giving Zhou Yuan’s paper a few more pages.

The international evaluation is also very pertinent, unlike the domestic Zhan Ting, Wu Sheng and others who boast about others.

They are very direct, licking people clearly.

“He is an opener in this field!” The award committee on IBRO’s official website commented on Zhou Yuan’s contribution.

“Professor Zhou Yuan’s research will bring the gospel to countless depression patients! He is more like the god of depression patients!” said psychiatrist Nashurd.

“It’s shocking that it was not those of us who had walked over from the old era that made a path in the field of depression in the end. One person has come out of the new era, and he is also the first person in the new era.”

Richard: “Yes, Zhou Yuan is awesome!”

“???”

What am I…

You, a hand surgeon, came to our psychiatric department to join in the fun! .

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