Start with Cell Editor
Chapter 142
Chapter 142
Chapter 143 active integration into the cancer cells (perfection Order)
“cancer!
Lu Li lying against the engineering chair, my mind flashed the words, followed, his mind would automatically emerge out of the relevant knowledge.
Cancer, in fact, the body has occurred cancer, the cancer cells become part of the cancer cells and normal cells different, can proliferate indefinitely, in other words, cancer cells can achieve immortality alternative.
Many laboratories are now in HeLa cell lines used, it all comes from a lady with cervical cancer 60 years ago, called Hai Tara Alex, 60 years later, the HeLa cell line has been strong proliferation, if given adequate nutrition, it can continue to grow.
Therefore, to cure cancer, it is necessary to kill all the cancer cells in the body.
Otherwise, sooner or later recurrence day.
In addition, cancer is actually a gene mutation.
Everyone’s body has proto-oncogenes and tumor suppressor genes.
Proto-oncogene in charge of cell division and proliferation cycle, human growth need it. At the same time the human body as well as tumor suppressor genes, it can inhibit abnormal cell proliferation.
Usually, proto-oncogenes and tumor suppressor genes play a role in normal, they are the normal gene in cells.
However, proto-oncogenes and tumor suppressor gene mutations occur once, you can not regulate normal cell division, this time, the cells became cancerous cells can proliferate indefinitely, no longer subject to human control.
Currently “It seems that 02 I have two ways to solve cancer.”
“The first is gene therapy, tumor suppressor gene introduced into cancer patients to suppress abnormal proliferation of cancer cells, or directly by the normal proto-oncogenes and tumor suppressor genes, the original substitution occurs oncogenes and tumor suppressor gene mutations.
The second “approach is the same as the treatment of AIDS, the use of macrophages again, macrophages already have the ability to ingest cancer cells, I just let macrophages can identify cancer cells on it.”
“The second way is simpler, but also facilitate mass production.
“Ah, I chose the second option.”
After Lu Li make a decision, they came to the sample library research and development centers, there are a variety of experimental samples, viruses, bacteria, cells, all have.
“Boss, you want to sample what?”
Lu Li had just entered the sample library, there will be a King said to him, King Kong is only a sample library administrator, previously managed by humans, but Lu Li King Kong feel more attentive, more patient, more reliable, He will be replaced by the King Kong. In addition to the administrator a lot of work, research and development center of sample libraries, such as cleaners, mechanics, are handed over to the King Kong
Because Diamond enough to do the job, but also more reliable.
“I need a sample of cancer cells, cancer cells each gave me an order.”
Lu Li ordered.
“clear.”
Then, King Kong will be busy up, samples of various cancer cells have a pick, put in a special box to save reagent biological samples, and after the reagent tank and handed Lu Li.
After Lu Li took the reagent box, then returned directly laboratory, and then he opened the reagent box, picked up a reagent tubes filled with cancer cells.
Reagent tubing bore the label: lung cancer cells, derived from patients with lung cancer Hao
“This is to make everyone feel fear of cancer cells ah.
Lu Li’s face looked indifferent liquid reagent tube, a curious glance for a moment, then opened stopper reagent tube, the liquid reagent tube fell on his left index finger.
In an instant.
In the helper cells of the editor, there are thousands of lung cancer cells into his body.
Subsequently, Lu Li a further tube opens other agents, and the like after he started, and the body has various cancer cells of lung cancer, blood cancer, skin cancer cell wait.
If ordinary people, must now Huangde one.
But he is very calm in the study of lung cancer cells.
In the helper cells of the editor, who controlled the lung cells from patients with lung cancer were split Wang Hao, a becomes two, two become four.
Of course, he is not simply watching a show, he is observing in detail all the dynamic changes in the process of lung cancer cell division.
Next, he began to observe all the dynamic changes in the division of skin cancer cells.
He wants to find out the common characteristics of these cancer cells, and then transform the macrophages so that the macrophages can recognize these common characteristics, and then target the cancer cells for precise strikes.
In the next week, Lu Li has been immersed in the experiment. He observed in detail the process of cancer cell division tens of thousands of times, and compared it with the process of normal cell division, and then analyzed the protein of cancer cells in detail. , Genes and other substances are different from normal cells, and finally found 13 kinds of proteins specific to cancer cells.
Normal cells will not secrete these proteins.
Then it’s much easier.
Lu Li only needs to modify the macrophages so that the macrophages can recognize the 13 kinds of cancer-specific proteins, so as to lock the identity of the cancer cells, and then directly engulf and digest the cancer cells.
In the laboratory.
Lu Li is constantly trying to modify macrophages.
“The 2257th gene editing has been able to identify lung cancer cells and blood cancer cells, and successfully eliminated these two types of cancer cells. It is necessary to add the ability to recognize other cancer cells.
“For the 3752th gene editing, the modified macrophages will attack normal skin cells, and the cause must be found out immediately.”
“The 5325th gene editing…very good! It has been able to recognize all kinds of cancer cells, even uterine cancer cells can recognize phagocytosis, saying that I have sacrificed quite a lot in order to conquer cancer.
Lu Li couldn’t help but smiled, even in the mood to tease himself.
Conquered cancer in a week, at this speed, who else can do it besides him?
Of course, this is also related to his accumulated rich knowledge and experience.
Apart from other things, his accumulated experience in genetic modification of macrophages played a very important role when he was studying AIDS specific drugs. And his understanding of human cell genes and genes played a decisive role.
“Well, first make macrophages that can recognize and destroy cancer cells in the laboratory, and then I can rest for a while.
Lu Li murmured and got busy again, using single-base gene editing technology to edit the genes of macrophages. Because it was a copying operation, the speed was still very fast. After three hours, he modified it. Hundreds of macrophages.
It’s just that it can no longer be named the new macrophage, which has the same name as the new macrophage for the treatment of AIDS.
Forget it, “just name the macrophage 843 that treats AIDS as the new macrophage No. 1,” and the macrophage that treats cancer as the “new macrophage No. 2”.
Lu Li didn’t struggle with this kind of thing, just chose a name, and then started experimenting.
The effect of the new macrophage No. 2 needs to be experimented to know.
“Well, start putting cancer cells.”
Lu Li divided the cancer cell samples that were not used up last time into ten, put them into ten petri dishes, and then injected the cultured blood with No. 2 new macrophages and observed them carefully.
Through the electron microscope, Lu Li found that these No. 2 new macrophages did not disappoint him. When they encountered cancer cells, they would rush up and then swallow them.
Cancer cells are not the same as HIV. They have no fighting power. As long as they are swallowed by macrophages, there is only one dead end.
One minute passed.
Two minutes passed.
Two hours passed.
There are no more cancer cells in the ten petri dishes, only the murderous No. 2 new macrophages.
See this scene.
Lu Li was excited again.
But to be honest, the sense of accomplishment is not as good as when he conquered AIDS, because he has gone through too many big scenes now. This kind of research project that is not difficult, even if the economic value is great, brings him a sense of accomplishment and excitement. It is also limited.
“Ah, the next animal experiments and human experiments, Xu Xiaochuan on to it, I rest a few days, began to study human evolution, this is a challenging research project!”
With this intention, Lu Li pulled out his cellphone and dialed the phone Xu Xiaochuan.
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