Doctor: start with the heart

Chapter 141 The Problem of Carrier Selection

Chapter 141 The Problem of Carrier Selection

After the meeting.

Xu Minghang took Su Xiao together to cultivate kidney mesenchymal stem cells, while Zhao Xu, Sun Chang, and Su Xiao wanted to discuss the matter of cultivating artificial kidneys together.

"Student, I think Dr. Su wants to be in your group."

Sun Chang looked at Zhao Xu, suddenly smiled and said.

I don't know when it started, Sun Chang, who has always been serious and serious, also began to be a little lively.

Maybe because she joined the research center, the relaxed atmosphere here allowed her to slowly release her nature?
"It's not just a little bit, it's almost like rushing forward."

Lu Chen chuckled and said with some disdain, pursing his lips.

She saw Su Xiao's small movements and eyes just now.

She doesn't bother to do Su Xiao's things.

After all, he is also an elite who has returned to China after studying, so he has no reserve at all?
Ha ha!

Zhao Xu looked weird and looked at Lu Chen. Why did she feel weird when she said this.

"Doctor Zhao, do you think I'm right?"

Lu Chen asked Zhao Xu again, feeling as though he wanted him to uphold justice.

"Uh... talk about the plan, talk about the plan."

Zhao Xu didn't know how to answer Lu Chen's question, and felt that no answer was right.

It's very troublesome for this woman to work together.

However, no matter in terms of ability, quality or other aspects, in the attached hospital, these girls are really stronger.

After all, medicine is a very boring subject. There are too many things to memorize and work hard to learn. Without a smart brain and a heart that can endure loneliness, it is impossible to study medicine well.

This has led to a situation where there are more women than men in medical school.

Like Xu Minghang and Zhao Xu, it is already very good to stand out from the large female army.

In fact, not only in medicine, but also in other industries, especially in various establishment examinations, women are also very powerful.

This directly led to some units setting up separate posts for men and women when recruiting for exams. Otherwise, in terms of exams alone, all the recruits might be girls.

"Student, have you thought about what carrier to use for artificial kidney cultivation?"

Sun Chang looked at Lu Chen, smiled knowingly, and said slowly.

To artificially cultivate a kidney, there must be an animal carrier, that is, to cultivate a transplantable organ in an animal, and then transplant it into a human body.

The method of cultivating artificial organs directly in the culture fluid, the current technology is far from reaching that level.

"At this stage, we can only use experimental large white pigs as carriers. However, there is a problem here, that is, the growth cycle of large white pigs. Even if various methods are used to promote growth, the shortest time for a large white pig to grow to maturity is the shortest. It takes about a year. That is to say, it takes about a year before the human organs cultivated in the large white pigs used in the experiment can grow and mature for transplantation."

Zhao Xu thought for a while and said, this is what he is most worried about right now.

He can develop a stem cell inducer, which can greatly shorten the time for stem cell cultivation and increase the success rate.

But he knows very little about animal genetics, and it is impossible to suddenly develop that kind of large white pig for experiments that can be fully matured in one to two months in a short period of time. If it can be done, it is not science, but a myth .

"Why not a primate, like an orangutan or a baboon?"

Lu Chen asked a little puzzled.

"Genetically speaking, primate orangutans and baboons are closer to human genes, and when the human organs bred are transplanted into humans, the chances of rejection will be smaller."

After a pause, Lu Chen expressed his thoughts again.

"Your idea is good, but the breeding time of primates is long, the survival rate is low, and the cost of feeding is high, especially now that many primates have become endangered species or protected animals, which further limits the use of primates. Long animals are used as experimental animals. As a mammal, pigs are very similar to humans. They are similar to humans in terms of organ size, physiology and biochemistry, etc. They can continuously provide experimental animals for xenogeneic organ transplantation Furthermore, humans have kept pigs as domestic animals for a long time. Therefore, after such a long period of iterative cultivation, the current experimental large white pigs are very suitable for cultivating human organs."

Zhao Xu explained.

"Well, among all the animals, pigs are indeed the most suitable animals to be used as culture carriers. After all, they are all mammals, with similar body and physiological structures. If they are cultivated and transplanted, the probability of rejection is also very low. of."

Sun Chang also said slowly.

"Then how to solve the problem of the cultivation cycle? As far as I know, the Landrace pig, which grows the fastest now, needs at least a year or so to fully mature."

Lu Chen nodded and raised his own question again.

"This is indeed a difficult problem. After the meeting, everyone should think about how to solve this problem."

Zhao Xu thought about it for a while, but he couldn't think of any good way to solve this problem for the time being. The growth cycle of pigs is not a problem that can be solved in a while.

However, the purpose of setting up a group is to allow everyone to brainstorm and work together to solve problems.

One person counts short, two counts long, this is an unshakable truth since ancient times.

There is even a saying like "Three Stooges are like Zhuge Liang".

"You said, what would the patient think if he knew that the artificial kidney he would transplant in the future was grown from a pig and contained some pig genes?"

Lu Chen said suddenly again.

"Let's save our lives. This is not within our scope of consideration. This is a problem for medical psychologists to solve."

Sun Chang glanced at Lu Chen and said.

I can't save my life, and I'm still worrying about where the transplanted kidney came from. Isn't this idle? !

"Xenotransplantation is the direction of development in the field of regenerative transplantation in the future, and more and more people will undergo xenotransplantation in the future."

Zhao Xu said.

"Aren't there still mechanical artificial organs? I read the literature recently, and there have been artificial lungs and artificial hearts abroad."

Lu Chen continued.

"Have you considered the issue of cost? As far as the artificial heart you mentioned, the cost is about 100 million, which does not include the cost of treatment. How many patients can afford such a high price? But with xenotransplantation, especially For pigs, the cost will be reduced to one-fifth or even less. This price advantage is very strong.”

Zhao Xu asked back.

This is the rule of the poor and the rule of the rich.

From a practical point of view, of course, artificial mechanical organs are better. After all, they are creations of cutting-edge human engineering and material science. Many materials used in artificial organs are products of space technology.

Especially the artificial mechanical heart is very powerful. After the technology is further developed, repairing and replacing parts is as simple as repairing a car.

But in contrast to xenotransplantation, in the process of cultivation and transplantation, some animal genes will always enter and fuse into the human body. It is completely unknown what impact this part of animal genes will have on the human body.

At this moment, Zhao Xu remembered that when the system gave stem cells to cultivate and reshape tissues and organs, there was another line of reminders.

That is the combination of this technology carefully and neuro-mechanical technology.

That is to say, whether it is purely biological or purely mechanical, in the evaluation of the system, it is just a pure biomedical technology.

But this creature plus machinery, combined with nerve splicing technology, will have a great possibility to change the pattern of the entire world.

Even the system has specifically explained and warned, which shows that this way of combining technologies is indeed extraordinary.

"That's right, and biological gene technology actually has a lower threshold than cutting-edge electromechanical technology."

Hearing Zhao Xu's words, Lu Chen also nodded, saying that Zhao Xu's judgment was indeed very possible.

In reality, how many good technologies, technologies that can benefit the crowd, cannot benefit the public because of price and cost issues, and become exclusive to a few people.

"Well, that's the end of the discussion. Everyone think about it and see if there is any way to solve the problem of pig growth cycle and organ maturation cycle. Dr. Xu and Dr. Su should be able to buy us some time."

There was no clue in his mind, and Zhao Xu was in a slightly less beautiful mood, so he announced the end of the meeting.

"Ah."

Sun Chang and Lu Chen looked at each other, and they both nodded at the same time, as if they had something to say.

"What's wrong? Is there anything else?"

Seeing that Lu Chen and Sun Chang had something to say, Zhao Xu couldn't help asking.

"Sister Sun, tell me..."

Lu Chen glanced at Sun Chang and said.

"It's like this. Director Tian discussed with me about the group accommodation mentioned earlier, and the place to live has been found."

Sun Chang said slowly.

"So fast?"

Zhao Xu couldn't believe it. It only took a day or two, how did he find it?

"Just a little closer to the hospital, the environment and the price are right, that's all. Isn't this a very simple thing?!"

Sun Chang looked like Zhao Xu was making a fuss.

Now the real estate market is sluggish, especially the rental market, which is in the current situation where there are many people and few houses, especially in the villa area, few people will rent villas now.

What Sun Chang and Tian Jinzhong chose was a single-family villa with a yard and so on. They were not short of money, so they naturally wanted to find the best one.

"Well, it's up to you to decide."

Zhao Xu nodded.

"Don't you ask the price? It's your money."

Sun Chang said with a smile.

"As long as you don't overspend."

Zhao Xuhun said indifferently.

400 million, which is only 50.00% of the first phase of the patent fee, and there will be a second and third phase in the future, and there will be more patent fees in the future.

"Yes, you are a rich man now, and you really don't care about such a small amount of money."

Sun Chang smiled again and said.

The market value of stem cell inducers is at least billions, and this 400 million is indeed just the beginning.

However, this does not mean that Sun Chang, Lu Chen, Su Xiao, and Jiang Xiaoqi will live in peace of mind, after all, they did not contribute to this patent.

"We have all discussed it. The biggest room is reserved for you. If you don't go, we won't go."

Lu Chen said seriously.

"Is this what you two are talking about?"

Zhao Xu asked strangely.

"Yes, you are a rich man. If you pay the money, if you don't live in it, no one will live in it."

Sun Chang complained.

"Uh.."

Hearing what Sun Chang said, Zhao Xu couldn't help but glance at Sun Chang. If it weren't for Sun Chang's ideas, he wouldn't have suggested any group accommodation.

Could it be that this senior sister, what happened recently, urgently needs someone by her side to experience the warmth of the collective?

Zhao Xu couldn't help thinking that Sun Chang, who had always been indifferent, was so abnormal.

However, Sun Chang's proposal is not considered overstepping, but also as a subordinate to fight for benefits for himself and other colleagues.

Of course, this is also very beneficial for her to be the deputy team leader in the future, after all, it is the benefit she asked for.

"You just need to reserve a room, I will live there when I have time."

Both Sun Chang and Lu Chen said so, and it was hard for Zhao Xu to refuse directly.

"Then let's go together after get off work. We'll have a housewarming party tonight."

Sun Chang said with a smile.

"You can arrange it."

Zhao Xu replied with a flat face.

"Then it's settled."

Lu Chen had a happy face, but she didn't know what she was happy about.

However, when she thought of living with Su Xiao in the future, she was not very happy.

Tian Jinzhong and Sun Chang decided to rent a villa. She and Sun Chang went to see it together. It was a villa in Qianlitun, the core business district. lock up.

To be honest, if it weren't for the benefits that Sun Chang fought for, she would not be able to afford the monthly rent of tens of thousands of dollars for Lu Chen's own salary, let alone a villa, or an apartment near Qianlitun. .

You know, as the attending doctor of the First Affiliated Hospital of Beishi, the annual salary is more than 20 yuan, which is actually not too small.

Therefore, the money spent on rent a month is at most five or six thousand. For this amount of money, in Beishi, especially the core business district, you can only rent a small apartment with a few dozen square meters. The experience of living here is definitely It is not as good as a big villa.

Lu Chen's situation is like this, Su Xiao, Sun Chang and Jiang Xiaoqi are naturally similar.

Although their family background is good, but after working, everything is self-supporting.

Seeing that Sun Chang and Lu Chen looked happy, Zhao Xu realized that they really wanted to change to a better house. Sun Chang must have considered everyone's most urgent needs when he proposed this.

It's Zhao Xu's overthinking. The importance of basic necessities of life is still very important.

How many people spend their entire lives saving money just to have their own house in a place like Beishi?

Especially girls, the pursuit of life is still very high, and I must be very happy to move from a small apartment to a big villa.

Doctors are also human beings, and they also have normal needs for food, clothing, housing and transportation, but because of the particularity of their work, these needs have always been ignored by people.

(End of this chapter)

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