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Chapter 133 Large-scale scientific research seminar
Chapter 133 Large-scale scientific research seminar
For the academic circles in Shanxi Province, these few days are very extraordinary.
The large-scale academic seminar jointly organized by Jinxi University of Traditional Chinese Medicine and fifteen colleges and universities in Jinxi Province was officially held!
This is a discussion lecture on academic exchange and experience. The keynote speaker is Keao Drapes, the associate editor of the world-class journal "Cell".
It can be said that this is the largest seminar on academic seminars ever held in Shanxi Province.
This meeting aroused great attention from the Provincial Health and Family Planning Commission and the Provincial Department of Education, and specially approved the Provincial Gymnasium.
Of course, one of the main reasons is that there are too many people attending the seminar, which cannot be accommodated in general academic exhibition halls.
For a time, this meeting also attracted the attention of countless people from all over the country.
After all, in everyone's impression, Jinxi has always been a weak area for masters and scientific research. I didn't expect to invite the deputy editor-in-chief of "cell".
This matter is also buzzing, attracting the participation of many academic enthusiasts and scientific researchers.
However, when everyone was paying attention to this matter, Bai Ye went to the hotel to study the data day and night.
This data is too complicated and messy.
but……
This is not a bad thing, it can even be said to be a good thing!
Why do you say that?
Because Bai Ye discovered that there are actually many core technologies hidden in it, and these technologies are unique technologies of large foreign scientific research bases.
After two days of research, Bai Ye finally figured out what these data are.
For some reason, Ke Ao did not explain clearly.
This is the whole process of developing a new drug.
This process took more than 3 years.
Maybe the clinical trial process in the later period will be longer, ten or eight years, although I don't know why the subsequent data is lost.
But this process is already very precious.
From the stage of drug conception, to the preparation of new drugs, to the design of new drugs, the development and production of new drugs, and clinical trials, it is a complete and mature new drug research and development system.
This drug is very precious, and it is a molecular targeted drug for the treatment of malignant tumors.
At present, the cause of the tumor is still unclear, so this experiment uses single-cell sequencing, that is, a single cell is used as a template for downstream next-generation sequencing research.
At present, the most common single-cell sequencing is used in the direction of tumors.
After Bai Ye saw this sophisticated thing, he suddenly felt that his head was too big.
One of the most difficult directions in bioengineering is genetic engineering, and the first step in this experiment is genetic engineering, which is the most cutting-edge scientific research direction in the world.
The development of second-generation sequencing technology has made people realize that the relationship between human diseases and genome variation is becoming more and more serious.
However, the occurrence of tumor diseases occurs precisely at the monoclonal level, which makes it necessary to detect the variation of the nucleotide level of a single cell nucleus.
And the content of the first large part of the data is precisely to carry out a systematic analysis of the pre-implantation, prenatal, screening embryos, etc. for the implantation conception stage of the experiment.
Single-cell sequencing mainly involves two aspects: single-cell genome sequencing and transcriptome sequencing. The DNA and RNA sequences of a single cell are analyzed and compared to reveal changes in the genome and transcriptome.
The data in the first large stage is mainly for observation, to observe the transcription and translation process of single cells.
And their experimental process is mainly to continuously culture single cells, and then cause cancer under various external conditions. This process is within the scope of detection.
To carefully observe the process of transcription and translation, a variation of DNA and RNA.
Of course, this is the process of experimentation, but this is not Bai Ye's job, Bai Ye's job is to study data.
However, such molecularly targeted drugs, especially molecularly targeted drugs studied at the genetic level, are rare in China, and the experience and technology in this area are insufficient. If this process is carefully sorted out, it will be very valuable.
Through these observed data, find the result.
Bai Ye's calculation went smoothly, surprisingly smoothly.
In one day, Bai Ye got the results of the first part.
The mutation point has been found, and the result of the mutation is also very accurate.
However, to Bai Ye's surprise, the end of this data has a result!
At the end of the first stage, the results of the data analysis are written.
This result is exactly the same as Bai Ye's calculation.
This made Bai Ye embarrassed.
Ke Ao came back at night, looked at the confused Bai Ye, and asked what happened.
Bai Ye then said: "I calculated the result of the first part, but... I found that there is a summary in the ending below, and the other party's answer is exactly the same as my calculation."
Ke Ao seemed to know the result, and asked with a frown, "Is there a problem with the analysis of the first process?"
Bai Ye shook his head: "No, there is no problem! I can assure you that there is no problem with the data analysis results of the first part, and... what do you want me to calculate?"
When Ke Ao heard Bai Ye's words, he became a little restless and walked around the room without speaking.
It took a long time before he said as if he was struggling: "You calculate the data in the second part, calculate carefully, pay attention to every detail, and see if there are any problems. Remember... don't miss any clues..."
When speaking, Bai Ye felt that Ke Ao's voice, which was a bit sharp on weekdays, turned out to be a lot hoarse!
what on earth is this kind of happenings?
Bai Ye has been thinking about this data all night.
There is no problem at all, and I calculated it again and again, but the result was the same as the other party.
Even the probability is exactly the same!
At dawn the next day, Bai Ye and Ke Ao had a buffet breakfast together. During the meal, Ke Ao may have not slept well last night, and his expression was a little sluggish.
Before leaving, Ke Ao hesitated to speak, but turned around and left again.
In the following time, Bai Ye ignored the purpose of the experiment and the records of those experimental methods.
After all, the above is not written in detail, it just writes the method used to get a certain step, and then it is the data result.The core technology is simply not available.
So, simply do not bother!
Study the data well.
In this way, the speed is significantly accelerated.
In three days, Bai Ye calculated the second part and came up with the result...
Well, not surprisingly, the result was exactly the same as the other party's.
This is awkward...
This...cooperated with me and didn't do anything?
Even if there are a bunch of results that are exactly the same as the answers?
Bai Ye would be happy if he took the exam, after all, it was exactly the same as the correct answer, so why not be unhappy?
But this is not an exam, and looking at Ke Ao's state, Bai Ye feels that the purpose of his calculation is definitely not to verify the correctness of this answer!
Could it be...he wanted a different result?
Today, Ke Ao's lecture has ended, and everyone has a dinner in the evening to express their gratitude to the lecturers.
早早早~~感谢墨初兄5000打赏,感谢欧阳四天1100打赏,还有书友160208223731291的1100打赏,还有豆粉1000、国士无双呵呵、jiliwala的100打赏~谢谢大伙儿的支持!
(End of this chapter)
For the academic circles in Shanxi Province, these few days are very extraordinary.
The large-scale academic seminar jointly organized by Jinxi University of Traditional Chinese Medicine and fifteen colleges and universities in Jinxi Province was officially held!
This is a discussion lecture on academic exchange and experience. The keynote speaker is Keao Drapes, the associate editor of the world-class journal "Cell".
It can be said that this is the largest seminar on academic seminars ever held in Shanxi Province.
This meeting aroused great attention from the Provincial Health and Family Planning Commission and the Provincial Department of Education, and specially approved the Provincial Gymnasium.
Of course, one of the main reasons is that there are too many people attending the seminar, which cannot be accommodated in general academic exhibition halls.
For a time, this meeting also attracted the attention of countless people from all over the country.
After all, in everyone's impression, Jinxi has always been a weak area for masters and scientific research. I didn't expect to invite the deputy editor-in-chief of "cell".
This matter is also buzzing, attracting the participation of many academic enthusiasts and scientific researchers.
However, when everyone was paying attention to this matter, Bai Ye went to the hotel to study the data day and night.
This data is too complicated and messy.
but……
This is not a bad thing, it can even be said to be a good thing!
Why do you say that?
Because Bai Ye discovered that there are actually many core technologies hidden in it, and these technologies are unique technologies of large foreign scientific research bases.
After two days of research, Bai Ye finally figured out what these data are.
For some reason, Ke Ao did not explain clearly.
This is the whole process of developing a new drug.
This process took more than 3 years.
Maybe the clinical trial process in the later period will be longer, ten or eight years, although I don't know why the subsequent data is lost.
But this process is already very precious.
From the stage of drug conception, to the preparation of new drugs, to the design of new drugs, the development and production of new drugs, and clinical trials, it is a complete and mature new drug research and development system.
This drug is very precious, and it is a molecular targeted drug for the treatment of malignant tumors.
At present, the cause of the tumor is still unclear, so this experiment uses single-cell sequencing, that is, a single cell is used as a template for downstream next-generation sequencing research.
At present, the most common single-cell sequencing is used in the direction of tumors.
After Bai Ye saw this sophisticated thing, he suddenly felt that his head was too big.
One of the most difficult directions in bioengineering is genetic engineering, and the first step in this experiment is genetic engineering, which is the most cutting-edge scientific research direction in the world.
The development of second-generation sequencing technology has made people realize that the relationship between human diseases and genome variation is becoming more and more serious.
However, the occurrence of tumor diseases occurs precisely at the monoclonal level, which makes it necessary to detect the variation of the nucleotide level of a single cell nucleus.
And the content of the first large part of the data is precisely to carry out a systematic analysis of the pre-implantation, prenatal, screening embryos, etc. for the implantation conception stage of the experiment.
Single-cell sequencing mainly involves two aspects: single-cell genome sequencing and transcriptome sequencing. The DNA and RNA sequences of a single cell are analyzed and compared to reveal changes in the genome and transcriptome.
The data in the first large stage is mainly for observation, to observe the transcription and translation process of single cells.
And their experimental process is mainly to continuously culture single cells, and then cause cancer under various external conditions. This process is within the scope of detection.
To carefully observe the process of transcription and translation, a variation of DNA and RNA.
Of course, this is the process of experimentation, but this is not Bai Ye's job, Bai Ye's job is to study data.
However, such molecularly targeted drugs, especially molecularly targeted drugs studied at the genetic level, are rare in China, and the experience and technology in this area are insufficient. If this process is carefully sorted out, it will be very valuable.
Through these observed data, find the result.
Bai Ye's calculation went smoothly, surprisingly smoothly.
In one day, Bai Ye got the results of the first part.
The mutation point has been found, and the result of the mutation is also very accurate.
However, to Bai Ye's surprise, the end of this data has a result!
At the end of the first stage, the results of the data analysis are written.
This result is exactly the same as Bai Ye's calculation.
This made Bai Ye embarrassed.
Ke Ao came back at night, looked at the confused Bai Ye, and asked what happened.
Bai Ye then said: "I calculated the result of the first part, but... I found that there is a summary in the ending below, and the other party's answer is exactly the same as my calculation."
Ke Ao seemed to know the result, and asked with a frown, "Is there a problem with the analysis of the first process?"
Bai Ye shook his head: "No, there is no problem! I can assure you that there is no problem with the data analysis results of the first part, and... what do you want me to calculate?"
When Ke Ao heard Bai Ye's words, he became a little restless and walked around the room without speaking.
It took a long time before he said as if he was struggling: "You calculate the data in the second part, calculate carefully, pay attention to every detail, and see if there are any problems. Remember... don't miss any clues..."
When speaking, Bai Ye felt that Ke Ao's voice, which was a bit sharp on weekdays, turned out to be a lot hoarse!
what on earth is this kind of happenings?
Bai Ye has been thinking about this data all night.
There is no problem at all, and I calculated it again and again, but the result was the same as the other party.
Even the probability is exactly the same!
At dawn the next day, Bai Ye and Ke Ao had a buffet breakfast together. During the meal, Ke Ao may have not slept well last night, and his expression was a little sluggish.
Before leaving, Ke Ao hesitated to speak, but turned around and left again.
In the following time, Bai Ye ignored the purpose of the experiment and the records of those experimental methods.
After all, the above is not written in detail, it just writes the method used to get a certain step, and then it is the data result.The core technology is simply not available.
So, simply do not bother!
Study the data well.
In this way, the speed is significantly accelerated.
In three days, Bai Ye calculated the second part and came up with the result...
Well, not surprisingly, the result was exactly the same as the other party's.
This is awkward...
This...cooperated with me and didn't do anything?
Even if there are a bunch of results that are exactly the same as the answers?
Bai Ye would be happy if he took the exam, after all, it was exactly the same as the correct answer, so why not be unhappy?
But this is not an exam, and looking at Ke Ao's state, Bai Ye feels that the purpose of his calculation is definitely not to verify the correctness of this answer!
Could it be...he wanted a different result?
Today, Ke Ao's lecture has ended, and everyone has a dinner in the evening to express their gratitude to the lecturers.
早早早~~感谢墨初兄5000打赏,感谢欧阳四天1100打赏,还有书友160208223731291的1100打赏,还有豆粉1000、国士无双呵呵、jiliwala的100打赏~谢谢大伙儿的支持!
(End of this chapter)
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