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Chapter 175 Right!Change car... (seeking subscription)
174:

Bai Ye found the scientific research process of Danshen Dropping Pills from the Internet. Because it is a decades-old drug, many papers have been published on the Internet, and many drugs similar to Danshen Dropping Pills have been produced.

At present, there are at least [-] or [-] kinds of Chinese patent medicines and liquids made from Danshen and Panax notoginseng on the market. Bai Ye gritted his teeth and spent money to buy every representative one.

After continuous separation and purification, Bai Ye was surprised to find that the specific medicinal ingredients contained in these different preparations were actually different.

For example, Compound Danshen Dripping Pills use Danshensu and Panax notoginseng saponins, but there is a Danshen tablet that uses cryptotanshinone, Danshenzhi 2A and Panax notoginseng saponins. Bai Ye is a little curious, what is the difference?

Because it is a common drug on the market and can stand clinical research, Bai Ye started the process of frantically searching for information.

Bai Ye suddenly understood Mr. Liu's good intentions. An old drug has been researched and developed for decades, and it has been studied thoroughly. Do experiments to study his efficacy and toxicity.

Mr. Liu meant that Bai Ye could be trained in this process. He believed in Bai Ye's ability to discover stable artemisinin complexes in artemisinin. Such a person's thinking ability and innovation ability can stand the test of time. from the test.

Mr. Liu asked Bai Ye to make Danqi Huoxue Pills, hoping that Bai Ye could find out the differences between these drugs on the market, why there are these differences, why some molecules should be removed, and why some compounds should be kept. These are all in the materials. Many can be found in the database.

After Bai Ye studied this drug, his level can be improved a lot, at least for these two drugs, Bai Ye can understand it thoroughly!
If you thoroughly understand one kind of medicine, you can eat it all over the world. Bai Ye’s mentor, Master Zhang Xuewen, has the nickname Zhang Danshen, because he has a very high grasp of Danshen, not only from the perspective of traditional Chinese medicine, but also from the perspective of modern medical research. have their own unique point of view.

There is a saying: If a person can do it, he will do it one line at a time, and one line at a time will do it.

If you can't do it, you can't do it in one line, you can't do it in one line, you can't do it in one line.

The same is true for medicines. If one medicine is made well, then other medicines can be made well.

So Mr. Liu just wanted Bai Ye to have a good start.

…………

Bai Ye has a temperament in his bones, and he must do the best when he wants to do it. If the experiment fails once, he will do it twice, and he will not stop until he gets the results of the drug experiment.

A week later, Bai Ye discovered that he spent more than 2 yuan on the medicine, which he never expected.

Fortunately, the Dongshan Animal Breeding Base has completely stopped operating. When Bai Ye was about to pay the rent two days ago, Meng Yunxi suddenly told him that he would not have to pay the rent this month because a company was preparing to take over and the two parties were negotiating. All right, let Bai Ye finish what he was doing as soon as possible.

There was nothing wrong with Bai Ye, the two parties met and the contract was terminated.

After the contract was terminated, the knife on Bai Ye's head was finally loosened, but he didn't expect that it was just the beginning, and he spent so much money just to buy the medicine for the experiment.

Thinking of the reagents used in the past two days, Bai Ye still felt that he should have an explanation with the school...

After all, there are more than 2 medicines, so this reagent is indispensable, right?

Thinking of this, Bai Ye suddenly felt that scientific research is really an extremely expensive thing.

What I did was still the simplest work, just separation and extraction, and I didn't conduct experiments, so I spent so much money. If I start researching again...

Bai Ye suddenly didn't dare to think about it anymore, scientific research without money as a guarantee is nonsense!

But let’s talk about these after the fact, let’s wait for the results of the experiment to talk about it, so I started to continue to study.

It is also a kind of faint happiness for Bai Ye to watch the rising experience of separation and extraction skills every night...

It's been another three days, and Bai Ye is already in a bit of a hurry. It's already mid-June, and everyone has started to carnival and nostalgia before graduation one after another, but Bai Ye is still trying and repeating.

Although no new substances have been discovered yet, Bai Ye is already very proficient in grasping these two drugs, even the separation and extraction have reached: lv4: 1024/30000.

But now Bai Ye is also bearish. If there is really a new discovery, it will have been discovered long ago. I am already very satisfied with this step.

It can be said that he now has a high degree of grasp of these two drugs and the preparation of Danshen Sanqi on the market.

Can't stop here?

Write all the research at this stage into a report and submit it?Anyway, the progress of the research is already very good.

During this period of time, Bai Ye also took out the "Chinese Medicine Processing Experience and Classification" that he got by lottery to read.

However, Danshen notoginseng is too mature a medicine, so there is not much difference between what is recorded above and now, the only difference is the difference in processing experience.

In this case, since it has nothing to do with cooking, then... what will happen if you add veratrum?

Everyone knows the eighteen anti-Chinese medicines, and all the ginseng, Xinshao, and veratrum!

Ginseng and veratrum will cause drug toxicity and incompatibility. Bai Ye suddenly thought, since he can't find anything new, can he add veratrum and see what happens?
Thinking of this, Bai Ye first inquired about the information, which was available. Many people had done this experiment, but no one really explored how the reaction occurred. They only said that it would aggravate the neurotoxic effect of veratrum.

Bai Ye felt that this was an opportunity, since he couldn't find anything new, he just created one.

…………

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Three days later, Bai Ye looked at the substance on the chromatograph in surprise, a little dumbfounded, did it really come out?

Bai Ye reacted the common substances in many ginseng with veratrum extract, and found that there was no effect at all.

So he tried to add another substance, which is also an extract of salvia miltiorrhiza, a substance called nortanshinone-3, but after putting it in, he was surprised to find that there was a reaction!
This nortanshinone-3 acts as a catalyst, catalyzing a series of reactions between the two extracts.

Bai Ye was stunned and found out!
However, when Bai Ye added this nortanshinone-3 to extracts of ginseng, Codonopsis pilosula, Panax notoginseng and other extracts to react with veratrum, there was no change at all.

What does it mean?
Specific Catalyst!

Specific enzymes!
Bai Ye suddenly felt dizzy, and quickly began to inquire about the clinical research and experimental observations of nortanshinone-3. This substance does exist, but it is rarely done in catalyst experiments, but this substance is still often tested clinically, because The content in salvia miltiorrhiza is very small, and it can only be manifested when it reacts with veratrum.

What's the point of this thing?
This time, when Bai Ye added nortanshinone-3 and danshensu to cook together, he found an abnormal change, nortanshinone-3 and danshensu disappeared!
It should be a new substance!
Bai Ye didn't know much about pharmacy. He searched books and frantically searched for information. He even missed the dinner before graduation.

After checking the information and doing research and analysis, Bai Ye discovered a problem, and he could no longer continue the work.

How to do?
cooperate!

A person's energy is too limited, so Bai Ye found Zhou Mao. After Zhou Mao heard the news, he stood up abruptly, got up and followed Bai Ye out.

In the laboratory, the two stayed up all night, Zhou Mao suddenly looked at Bai Ye with a solemn expression, and said:

"Do animal experiments and observe indicators!"

There are too many instruments and equipment needed for animal experiments, and the current laboratory is completely unable to meet them. However, Zhou Mao is the dean of the School of Traditional Chinese Medicine, so he still has the right to do so.

Scientific research is always sleepless nights.

Two weeks later, in the laboratory, Zhou Mao and Bai Ye met and smiled!
The result came out. When these two substances are used together, a new substance can be produced, and this substance can effectively improve the activity of antioxidant enzymes and reduce free radicals!
What does this mean?
It simply means that when these two drugs are used together, they will not improve blood circulation, nor will they expand coronary vessels, nor will they affect blood coagulation function.

He has only one simple but not simple function: scavenging oxygen free radicals.

What is an oxygen free radical, which is an oxidation product produced by the human body after metabolism every day. These substances will be produced in other situations: such as stress, smoking, radiation, exposure to pollutants...

Once there are too many oxygen free radicals in the body, it will damage the cell membrane, making the cells lose their stability and cannot work normally.

For example, it affects the secretion of hormones, conducts electrolytes and physiological signals, etc., and even causes some chronic diseases. It also causes DNA damage, causing tumors, cardiovascular diseases or cell apoptosis.

What is the end result?
Accelerate aging.

Therefore, it is now believed that taking antioxidant supplements regularly can neutralize the destructive power of this oxygen free radical, protect cells from oxidative damage, and achieve a process of delaying aging.

In fact, Danshen has the function of scavenging free radicals. As early as 1996, a research institute showed that tanshinone contained in Danshen injection can scavenge oxygen free radicals caused by myocardial infarction and protect myocardial cells from damage.

The Department of Pharmacology, School of Medicine, National University of Singapore also used scientific methods to study the curative effect of salvia miltiorrhiza made into western medicine, and found that salvia miltiorrhiza helps to increase the activity of antioxidant enzymes and reduce free radicals through the measurement of oxidase activity.

But no one found the final reason!
Bai Ye and Zhou Mao looked at each other, and finally got the result!
Zhou Mao looked at Bai Ye, and a smile appeared on his haggard face: "You... are really a genius!"

After getting along for the past few days, the relationship between the two has become better and better. It is no longer just a relationship between a teacher and a student. At first, Bai Ye called him Teacher Zhou, and later, he called him Uncle Zhou.

Bai Ye smiled, scratched his hair, it was a mess, he glanced at Zhou Mao: "Uncle Zhou, you can change the car now!"

Zhou Mao heard it: "You bastard! Haha... yes, change the car!"

(End of this chapter)