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Chapter 190 Successful Decryption (Subscribe)

Macalite frowned. This question undoubtedly questioned his answer, and the research and expression of genes is indeed full of randomness, so it is not easy for him to answer this question.

"These are two problems. The adaptability and stability of the mouse have nothing to do with it. It may have something to do with his own expression. I think this student should go back and make up for it. Is there anything else you want to ask?"

After Macalette said the words, the discussion immediately started.

Including Zhang Shulan also frowned, which is obviously a sophistry, gene expression is the cause of adaptation, and adaptability is also the result of gene expression.

This Macarette obviously couldn't handle Bai Ye's question, but he couldn't explain this question, so he couldn't explain why SHR used Wistar mice instead of SD or KM and other types of mice.

Or to put it another way...he didn't engage in research in this area at all, but made up nonsense answers.

Thinking of this, Zhang Shulan looked at the young Bai Ye with great interest.

I saw Bai Ye said lightly: "Can I think that the priority of SHR may not be able to stand the test of the market, or we can try to use other mice for research to see whether gene grafting can obtain a new of mature essential hypertensive mice?"

When Macalette heard it, he immediately said with a straight face: "Any experiment needs results and data to prove it. SHR can persist in being widely recognized internationally for several years. It needs to be supported by data and experiments, if not, your words are just a meaningless argument."

After speaking, Maccarette got up and left.

The meeting broke up unhappy, and Bai Ye undoubtedly ruined the venue for the new product launch of Ronka SHR.

However, Bai Ye has gained a lot. He feels that he has found a direction, that is, to start with SHR mice and study KM mice. Maybe he can find the mechanism for gene expression.

Since SHR has lost 100% of the anti-hypertensive gene after so many generations of development, but KM mice have it, it means that there is something in KM that controls the gene expression of KM mice.

Dong Cunguang looked at Bai Ye and gave a thumbs up.

"you are great!"

Bai Ye smiled mischievously. He didn't want to raise an argument, but just hoped to gain some knowledge.

The two got up and were about to leave when Zhang Shulan stepped forward.

Bai Ye was a little surprised. He had listened to the lectures given by Zhang Shulan, and they were very simple, without any academic exaggeration.

"professor Zhang?"

Zhang Shulan smiled: "You are very nice, do you do genetic engineering? What's your name?"

Bai Ye shook his head: "I am a medical student, and my name is Bai Ye."

Zhang Shulan's eyes lit up: "BPFH rated that Bai Ye?"

Bai Ye didn't expect to be so famous: "Yes."

When Zhang Shulan heard this, she raised her eyebrows in surprise, and smiled happily: "You are Bai Ye, the proud student that Mr. Liu praises all the time!"

Bai Ye was taken aback, a little confused, what's the situation?

Then Zhang Shulan smiled and said: "Isn't your advisor Liu Boli, Academician Liu? He praises you all day long, wishing to talk about you, how outstanding you are! When I heard what you said today, I also believed it. You are indeed an excellent person." boy!"

Bai Ye scratched his head in embarrassment and said thank you. Then he remembered that the teacher is also an academician of the Chinese Academy of Sciences, and he probably knew Professor Zhang as well.

Zhang Shulan said seriously at this time: "Actually, your idea is very good. Our research on mice has always been based on the latest foreign reports. We have been learning and never questioned. Your idea is worth a try. Yes, this is my phone number, if you don’t understand anything, come to the Chinese Academy of Sciences to find me.”

After speaking, Zhang Shulan read a series of phone calls to Bai Ye, and left with a smile.

Looking at Zhang Shulan's leaving figure, Bai Ye suddenly remembered something, and said hastily, "Mr. Zhang...don't tell my tutor that I'm studying mice again..."

Zhang Shulan paused when she heard the figure, almost sprained her feet, then laughed and walked away.

Bai Ye sighed, hey...he's going to be scolded for not doing his job properly again.

And Dong Cunguang's face was flushed and he pulled Bai Ye excitedly: "Zhang...Zhang...Professor Zhang actually left you a phone call!"

Bai Ye hummed: "Yes, you heard it too, didn't you remember it? I'll give it to you when I go back. Do you know Mr. Zhang?"

Dong Cunguang said shyly: "She is my idol, and many of her ideas have a great influence on me. I have always hoped to get a doctor's degree from Teacher Zhang..."

Bai Ye sighed: "Then why don't you say hello?"

Dong Cunguang said in embarrassment: "I'm too nervous to speak. I'm afraid that if I stutter, I will leave a bad impression on Mr. Zhang."

Bai Ye: "..."

At this meeting, Bai Ye felt that the 1000 yuan was not in vain. He spent a few meals, stayed in a high-end hotel for two days, met an international celebrity, got acquainted with a domestic celebrity, and had a research idea.

In general, Bai Ye gave himself full marks.

Back in the laboratory, Bai Ye started his research following the original train of thought.

After checking the information, it is especially for some basic subjects such as mouse anatomy and physiology. Fortunately, one method can master all methods, and the progress is still very fast.

One morning at the end of July, Bai Ye couldn't believe it, did he find it like this?

However, it was a bit too unbelievable.

Why do you say that this is just an ordinary base on the double helix structure of mouse DNA, guanine?

This thing can actually affect the expression of genes to achieve a special variation during transcription?

Bai Ye couldn't believe it. In order to confirm, he directly found the drug that was tested in the beginning and wanted to experiment.

Three days later, Bai Ye finally verified and came to a conclusion!
Under special circumstances, this guanine has a certain chance of causing RNA mutations, resulting in mutations in gene expression during translation!
This is the expression of the adaptability of mice in certain special environments.

Of course, this does not mean that all gene expression is related to the guanine in mice, but that the presence of this purine will affect the stability of the mouse gene structure and achieve certain mutations under special circumstances.

Bai Ye quietly looked at the laboratory in front of him and took a deep breath.

This should be the main reason for the failure of Ke Ao's experiment. Under the stimulation of that drug, the mice were stimulated by the drug, which caused the guanine to mutate, resulting in a change in the transcription and translation process of the DNA molecular structure, which inhibited the reproduction of tumor cells. .

In the final analysis, the reason is this guanine!

Decades of unsolved mysteries finally had a reason. Thinking of this, Bai Ye felt a burst of emotion. If the mouse experiment had failed, it would not have been used as a phase one clinical trial, and those patients would not have died.

Bai Ye sighed, maybe science develops in dialectics, maybe one day Newton's law will be overturned?

Bai Ye smiled, wrote down an answer in his notebook, sorted out the data, and put it in his bag.

(End of this chapter)