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Chapter 77 Thesis Preparation

After finding that molecule, Bai Ye turned on the computer and connected to the laboratory's proprietary database.

This is a small molecular compound with a very low content and a very simple molecular structure, but when this molecule works together with artemisinin, it often has a high curative effect and is very stable!
The result of statistical data analysis is that if other influencing factors are simply isolated, when this molecule is combined with artemisinin, the effect of treating malaria is obvious.

But what exactly is this molecule?Why did it play such a role, Bai Ye was a little puzzled!

Didn't they find this thing?

It is very possible that Bai Ye synthesized all the relevant data analysis in the past 15 years, and then found a check and balance point through that flash of inspiration!
Then this molecule was found.

Nobel laureate Joseph Goldstein once said:

"The development of biomedicine is mainly through two different approaches, one is discovery, and the other is invention and creation."

Bai Ye knew that he had discovered this thing through continuous calculation and verification. Of course, this thing is probably meaningless, and this is what you will do next.

Check it out!verify!
In the past two days, Bai Ye has frantically checked the literature, and carefully studied everything related to this molecule, even the things that extend out of this molecule.

Two days passed in the blink of an eye, Bai Ye tidied himself up, and then went to dinner parties and salons.

In this salon, no one underestimated Bai Ye. On the contrary, everyone looked forward to what kind of questions this young man would ask.

Bai Ye cherishes and attaches great importance to the opportunity to discuss with everyone. These people are all seniors, and Bai Ye directly unlocked ten times the experience.

He didn't feel distressed, he only had one month here, and how much he could learn would depend on himself in the final analysis. Half a month had passed in the blink of an eye, and Bai Ye felt the urgency of time more and more.

Bai Ye listened to everyone's chats, as if he was listening to an academic report. These are rich knowledge, but also naked experience!

He was very smart this time, and he took a small notebook. Whenever he heard something important or inspiring, he immediately wrote it down and waited to look it up when he went back.

This exchange is no longer limited to biochemistry, but broader, such as physiology, cell biology and other subtle angles, they explore the functions of cells in a simple way.

Such as changes in cell membrane permeability, and mitochondrial function and so on.

Intentionally or not, everyone talked about the basics, and occasionally gave Bai Ye a kind look.

Three hours later, everyone slowly fell silent, and suddenly Karis asked, "Bai Ye, do you have anything to say?"

Karius didn't say what you don't understand and need to ask, but whether you have any opinions. Although the meaning is not much different, it shows his fair recognition of Bai Ye. There is no academic level, and they are equal.

Even the simplest 1+1 and complex Goldbach conjecture.They are all academic discussions.

Bai Ye thought about it, and then brought this element up.

Karius is obviously familiar with this molecule: "This molecule should have no meaning, and it is very easy to separate. It is found in many compounds, just like water molecules. I really can't find its meaning. And..."

At this time, a black girl took over the topic: "Well, when I was doing the reagent stability test, I saw this thing, but I haven't paid much attention to it, because many experiments have also analyzed this molecule, and it doesn't have much significance."

Everyone shared their knowledge about this molecule.

And Bai Ye also recorded it carefully. This knowledge is very useful and directly opened a door for Bai Ye to deal with it from various aspects such as physiology and biochemistry, physical and chemical factors, drug metabolism, human body reaction, drug purification, compound matching, etc. An item to analyze.

After it was over, Bai Ye heard the system beep.

"Ding! The pharmacology skill has been raised to lv4!" Bai Ye was overjoyed, the pharmacology had actually improved!
Indeed, because this class mainly talks about the various properties and metabolism of drugs.

After sharing, Bai Ye still had a lot to say, but everyone was indeed tired. Bai Ye got up and smiled gratefully to everyone, and everyone responded kindly.

For such a little junior brother, everyone likes to support and support him very much. Moreover, the speed of this little junior brother's progress is really a bit fast.

Just as he was leaving, Karis suddenly stood up and said to Bai Ye: "I have other things to do this week, so you don't need to record the data for me."

Bai Ye was stunned for a moment, feeling a little regretful, because Caris taught him a lot.

Seeing Bai Ye's expression, Karius continued, "Haha! In the next half a month, I may go back to Denmark with Professor Tu to attend a conference. Of course, you can use my equipment!"

Suddenly Bai Ye's eyes lit up, can he use the instrument?

The opportunity is coming!

He had an idea about this molecule, what exactly does it do with artemisinin?
Bai Ye wanted to find out.

In the next week, Bai Ye took a leave of absence with the others and concentrated on going to the first group.

The others did not arrange work for Bai Ye, because they all knew that Bai Ye had recently made a discovery of his own.

This is a good thing!

For scientific researchers, it is a good thing to have an idea, at least you can start to verify your idea.

Based on the knowledge he had learned, Bai Ye separated artemisinin from its physical and chemical properties, and then purified and extracted it. This process is very basic.

Bai Ye worked on it for two days, and finally he was able to operate it perfectly.

In the following time, Bai Ye tried to add this molecule to artemisinin, but the two were not compatible at all. He consulted all the people in the first group, and they made many suggestions, such as considering using physical factors to fuse under the microscope. .

It's just...the requirements for the operator are too high, and it is very difficult for Bai Ye to meet them, so Bai Ye tests day and night.

Moreover, Bai Ye discovered that it is still difficult to achieve fusion of these two molecules, so...how can we achieve communion without affecting their molecular structure?
Bai Ye was very clever this time, and thought of the method of making traditional Chinese medicine.

As early as the Eastern Jin Dynasty, Ge Hong wrote in "Elbow Reserve Emergency Prescriptions": "Hold Artemisia annua, soak it in two liters of water, wring it out to get the juice, and take it as much as you want!"

Bai Ye was taken aback!
Instead of traditional boiling, we chose twisted juice. Is it because the high temperature will destroy the activity?
So when Bai Ye obtained artemisinin this time, he chose other methods.

Finally, on the sixth day, Bai Ye finally obtained the substance that co-existed with artemisinin.

Bai Ye named it: stable artemisinin complex.

That night, Bai Ye wrote the paper, retrospectively analyzing the data analysis and clinical efficacy of the stable artemisinin complex from 2001 to 2015.

The name of the title is: "A retrospective study on the efficacy and safety of stable artemisinin complexes".

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(End of this chapter)