The world's richest man started by developing gutter oil

Chapter 278 Chapter 268: Cut off Hu? Alpha 32 virus removal agent
The reason why Guoguo has not resumed negotiations with TSMC for so long is because Mr. Qiao suddenly suffered a stroke.

Cook was taking over the fruit company and had to postpone the progress of negotiations. In addition, the current situation of the fruit also made him very busy. What's more, the emergence of Deep Blue also took away a lot of the fruit market.

For Cook, his most important task now is to put things right and restore the fruit to its original appearance.

"Mr. Han, welcome to Wanwan." Zhang Mouzhong stood up from his seat and said with a smile.

I have to say that Zhang Mouzhong is really a cunning guy. He did not welcome Han Chen like others. Others welcomed Han Chen to their company, but Zhang Mouzhong welcomed Han Chen to Wanwan.

This opened up the whole situation at once, but don't be fooled by his appearance. This old guy is pro-American secretly, but it will be difficult for him to be pro-American in the future.

As long as he cooperates with Deep Blue Group, he will be firmly controlled by Deep Blue in the future.

why?
Because Deep Blue Group will definitely become TSMC’s largest customer. Once Deep Blue becomes TSMC’s largest customer, TSMC will definitely be included in the gray list. Once someone wants to take action against Deep Blue Group, TSMC will definitely be implicated by Deep Blue Group.

Even if TSMC flatters some people, it will be useless.

Because once TSMC loses Deep Blue as a customer, it will be equivalent to losing most of its revenue. It will be impossible for TSMC to find a manufacturer to replace Deep Blue in the short term.

"Hello, Mr. Zhang." Han Chen shook hands with Zhang Mouzhong and said with a smile.

"Mr. Han, I just made a pot of fine Tieguanyin, why don't we sit down and drink tea and chat." Zhang Mouzhong said with a smile.

"Okay." Han Chen smiled.

Then the two sat down, and Zhang Mouzhong poured Han Chen a cup of tea.

"Mr. Han, I heard that your company has a great demand for chip production capacity. Because of the large number of orders from major wafer factories, your company has not been able to get the production capacity it wants. Is Mr. Han coming to TSMC for this? About production capacity?" Zhang Mouzhong asked.

"Yes, in addition to producing mobile phone chips, our company now also produces routing chips and Bluetooth chips. The market demand for these two chips is also very large. As our mobile phone business expands, the production capacity of the chips will become more and more Big, so I want to find a manufacturer that can stably produce for Deep Blue." Han Chen said after picking up the tea cup and taking a sip.

"I wonder what your company's approximate monthly demand is?" Zhang Mouzhong asked.

"Based on current development trends, Deep Blue is expected to ship 8000 million mobile phones next year. With the popularization of Starlink and Listening technologies, Deep Blue Group's demand for chips will be around 1.8 million in the future," Han Chen said.

Zhang Mouzhong was shocked when he heard Han Chen's words. He didn't expect Deep Blue to have such a big demand for chips.

So did Zhang Mouzhong ever doubt what Han Chen said just now?

No.

Because he had already investigated Deep Blue Electronics before Han Chen arrived, and Deep Blue Electronics' shipments had been placed on his desk as early as this morning. It is very simple these days as long as you have money to investigate some data.

Since its launch, more than 1800 million DeepBlue mobile phones have been sold, which is only a little over a month ago.

Even if the shipments of Deep Blue Group show a month-on-month decline every month, Deep Blue Group’s mobile phone chips alone will be 1 million pieces in one year. In addition to mobile phones, Deep Blue also has two types of chips: routing and Bluetooth. Adding the two together in one year 1.8 million is also very normal.

Many new products now use Starlink and Listening technologies, which has also led to a shortage of routing and Bluetooth chips. User purchase orders have been scheduled until next year, and routing chip orders have already exceeded 2 million pieces.

"Mr. Han, in fact, we at TSMC cannot provide more production capacity to your company because we only have so many photolithography machines. Even if we give all our production capacity to your company, we will not be able to meet your company's requirements. The demand for production capacity, unless" Zhang Mouzhong took a sip of tea and stopped talking.

"Mr. Zhang hopes that we can sign a long-term cooperation agreement with your company." Han Chen said with a smile.

"Yes, if your company is willing to sign a long-term cooperation agreement with us, we can immediately purchase equipment and expand the factory. In addition, I also hope that your company can inject a sum of funds into TSMC, because TSMC currently reserves Funds are not very abundant.

The capital required to expand production is calculated in tens of billions. In order to complete the expansion task, we need to raise capital. Under the current situation, it is still difficult for TSMC to raise tens of billions. If Deep Blue Group is willing to inject part of the capital into TSMC , then TSMC’s financing situation will be much smoother. "Zhang Mouzhong said.

After all, Deep Blue Group is not a fruit company, and many capitals do not recognize Deep Blue Group. If TSMC wants to achieve Han Chen’s goal, it needs to invest at least 500 billion. If Deep Blue Group does not inject capital, TSMC may not be able to obtain that much financing.

You must know that the current TSMC is not the TSMC of later generations. TSMC only took off after getting orders for fruits.

If TSMC had not received the fruit order, TSMC would not have surpassed Shanxing.

"I wonder how much capital TSMC needs from DeepBlue?" Han Chen asked.

"At least 15 billion U.S. dollars, preferably 30 billion U.S. dollars." Zhang Mouzhong said.

"Yes, but I need TSMC to help Deep Blue Electronics develop the crooked mobile phone market." Han Chen said.

"The chairman of BayWan Mobile and the chairman of Chunghwa Telecom are very familiar with me. I can help Deep Blue contact them and let them introduce Deep Blue mobile phones." Zhang Mouzhong said with a smile.

Then the two talked about the details of the cooperation. This cooperation between the two parties was not a simple cooperation, and it involved many things.

In addition, once the two parties reach a cooperation, DeepBlue will become the top ten shareholders of TSMC. Han Chen will definitely make certain requirements to TSMC to ensure that his interests in TSMC are guaranteed.

Although Han Chen is not afraid that Wanwan will confiscate Shenlan's shares, he still has to fight for the rights and interests he strives for.

Han Chen’s first request is that TSMC must give all its existing production capacity to Deep Blue.

The second thing is that TSMC must expand production within one year.

The third thing is that TSMC must pay dividends every year since Deep Blue’s investment, and the annual dividend amount must not be less than 45% of profits.

The fourth thing is that when TSMC takes orders from some customers, Deep Blue has veto power as long as it does not affect TSMC's income.

The fifth thing is that TSMC must send employees to Shenzhen to jointly develop packaging processes with Deep Blue Semiconductor, and the patents developed will be distributed according to the investment ratio of both parties.

The sixth thing is that TSMC’s foundry price must be 3% lower than the market average price.

The seventh thing is that TSMC must look for financing in the mainland, and Deep Blue Capital will help TSMC take the lead. The reason why Han Chen requires TSMC to go to the mainland to find financing is because TSMC’s largest shareholder is Citibank of America. By then, the capital party led by Deep Blue Capital will become the largest shareholder of TSMC, and Deep Blue Group will have a certain say in TSMC. .

The reason why Han Chen did this was to focus on TSMC’s R&D capabilities.

At that time, even if Zhang Mouzhong wants to rebel, it will be very difficult. In addition, Citigroup will indirectly become an ally of Deep Blue. If something happens to TSMC, Citibank will not be in a better position.

If anything happens, Citibank will definitely secretly pass information to Deep Blue.

Of course there are many details besides these things.

The two talked all afternoon and ended at seven o'clock in the evening.

"Mr. Zhang, then we will leave the next thing to the people below. After the people below draft the contract, we will sign the contract. There will be no signing ceremony or anything like that. Our Deep Blue Group has always advocated low-key things. enterprise." Han Chen said.

"Mr. Han, it's getting late, why don't we have dinner together." Zhang Mouzhong said.

"Okay." Han Chen nodded.

Then Zhang Mouzhong took Han Chen to a nearby private restaurant for dinner.

September 2010, 9, China time.

While Han Chen was still sleeping, he was once again woken up by the system's weekly ringtone.

[This week’s special product: Alpha 32 virus removal potion, priced at 10 billion soft sister coins. 】

[Introduction: When your mother sees you, she won’t just remember your name but not your appearance. One bottle of refreshing, two bottles of refreshing, and three bottles of refreshing are not enough. It is best to drink seven more bottles to recover. 】

Han Chen was confused when he saw the introduction. He had never heard of the name Alpha 32 virus. The introduction of the system was confusing.

"What the hell is this?" Han Chen muttered.

If it weren't for the deep blue group's strong earning power, Han Chen would have been hesitant to buy it. However, it was certain that this thing was extraordinary, so Han Chen decided to spend 10 billion to buy it.

Then Han Chen got up and turned on his computer to submit the payment order, and sent a text message to the finance department for confirmation.

When the 10 billion money was transferred to the designated account, a USB flash drive appeared in front of Han Chen, and Han Chen inserted the USB flash drive into his laptop.

"It turns out that this thing is used to treat Alzheimer's disease." Han Chen was surprised after seeing the introduction in the document.

Seeing the introduction in the document, Han Chen remembered one thing. There had never been an effective treatment for Alzheimer's disease in his previous life. The reason why this happened was because of academic fraud. Everyone was accused of the "pioneer paper" of Alzheimer's disease. "Lied.

In 1906, the German pathologist Alois Alzheimer observed plaques and protein deposits in the brain when he dissected the brain of a patient with symptoms of dementia, and thus unveiled the molecular basis of AD molecular research. prelude.

In 1984, George Glenner, a pathologist at the University of California, San Diego, isolated these plaques and named them amyloid beta (Aβ).

In 1991, researchers found mutations in the precursor protein gene (APP) in patients with familial Alzheimer's disease and found that it was APP that was cleaved by proteases to produce this toxic Aβ.

These research findings indicate that Aβ is closely related to plaques in the brains of AD patients. From this, the hypothesis of amyloid-β protein, the causative mechanism of AD, has emerged. Clearing Aβ from the brain has become a reasonable therapeutic strategy for the prevention and treatment of AD.

Since then, the β-amyloid hypothesis has become popular, and the medical field has begun to focus on the research of Aβ. Pharmaceutical companies and research institutions have also carried out drug research and development around Aβ.

However, this research and development road is full of ups and downs. Whether it is immunotherapy dedicated to clearing Aβ or various therapies to reduce the production and aggregation of Aβ, they have fallen into the pit one after another. More and more voices have begun to question amyloid beta. hypothesis.

It was not until 2006 that the development of the Aβ hypothesis ushered in a turning point. A paper was published, which almost confirmed that Aβ is the fatal culprit of AD.

Sylvain Lesné, who was a graduate student at the University of Minnesota at the time, published an article in Nature titled "Specific β-amyloid protein in the brain impairs memory," pointing out that Aβ56, an oligomer of Aβ protein, can cause memory impairment.

Because of this research, Karen Ashe won the "Nobel Prize" in the field of AD - the Botan Gold Medal, the MetLife Foundation Alzheimer's Disease Research Award and other awards.

It was not until 2023 that this matter was noticed by a man named Schrag.

By chance, in order to prove that Cassava's research was fraudulent, Schrag logged on to PubPeer, an academic anti-fraud website.

When searching for "Alzheimer's disease" on PubPeer, posts about several papers in "The Journal of Neuroscience" caught Schrag's attention. Eventually Schrag accidentally discovered that Lesné's foundational paper also contained multiple tampering. image.

Schrag repeatedly processed the images through a technique called Western Blot, and found that specific protein bands involving the Aβ56 image had been cut, copied and pasted to fabricate the experimental results.

What actually causes memory impairment in humans is a virus called Alpha 32 virus.

It’s just that this virus is good at hiding and difficult to detect, and Karen Ashe is a faker, so this virus has not been discovered.

When Han Chen saw the main ingredient of the Alpha 32 virus elimination potion, he was a little bit speechless. The main ingredient of the Alpha 32 virus elimination potion turned out to be isatis root, which made Han Chen couldn't believe his eyes.

There is a substance in isatis root that can effectively kill the Alpha 32 virus. Of course, if you want to make the patient fully recover, it is not enough to rely on isatis root alone. You also need the combination of two traditional Chinese medicines: angelica and astragalus.

The anticoagulant, antithrombotic, and antioxidant effects of Angelica sinensis are very good. It has a protective effect on cerebral ischemic injury. Angelica sinensis can also delay muscle atrophy in the body, and it has a good effect on the recovery of myelin after sciatic nerve injury. ; Angelica sinensis has the functions of scavenging free radicals, protecting blood vessel nerve barriers, etc., and has a certain protective effect on ischemia-reperfusion injury of peripheral nerves. The trace elements contained in astragalus contribute to the repair and regeneration of nerve cells.

Another thing to mention is that the Alpha 32 virus-clearing drug is not taken orally, but is administered intravenously to treat Alzheimer's disease.

Injecting traditional Chinese medicine into the human body by injection can be said to be a very bold innovation. 99% of people have always believed that traditional Chinese medicine is used orally, but who has tried to inject traditional Chinese medicine into the human body through intravenous injection? Injected into the body to treat disease.

This treatment method can be said to be a very bold innovation, and it can also be said that it is the result of combining traditional Chinese and Western medicine.

To put it simply, there are many ways to do it, it just depends on whether you have thought of it or not.

(End of this chapter)